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《温病条辨》咳痰喘证治辨析

中国中医药现代远程教育 2024年第14期22卷 60-62页

作者：王颖王玉光张晓雷北京中医医院怀柔医院呼吸科北京101400 北京中医医院呼吸科北京100010

咳、痰、喘是呼吸科常见临床表现,可见于多系统疾病,病因广泛。特殊疾病的喘咳治疗较困难,如感冒后咳嗽、肺间质纤维化等。文章对《温病条辨》相关条文进行了梳理,发现其主要从风温、肺热、痰饮水湿、肺燥、津伤、肝肾阴亏、败血冲肺七... 详细信息

咳、痰、喘是呼吸科常见临床表现,可见于多系统疾病,病因广泛。特殊疾病的喘咳治疗较困难,如感冒后咳嗽、肺间质纤维化等。文章对《温病条辨》相关条文进行了梳理,发现其主要从风温、肺热、痰饮水湿、肺燥、津伤、肝肾阴亏、败血冲肺七个方面对外感温热病相关喘咳进行论述;历代对于湿证之喘咳论述较少,由于温病多夹杂痰湿,因此吴氏论述详细,补充了喘咳的证治范围。吴氏治疗喘咳并非单纯针对喘咳症状,而是针对其证候,或配伍理气止咳平喘药物如杏仁、旋覆花、桔梗、郁金、滑石等,证候解除则喘咳自止。临床内伤之人多有外感迁延不愈,外感之人多有内伤基础,因此《温病条辨》虽然为外感温热病之著作,但对于外感、内伤之喘咳均有一定借鉴意义。

关键词：咳痰喘胸闷咳嗽《温病条辨》

鄂尔多斯盆地东南部韩城地区延长组碎屑锆石U-Pb年代学特征及物源指示意义

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西北大学学报（自然科学版） 2024年第4期54卷 741-754页

作者：刘旭东张忠义彭恒刘江燕丰孝林张晓磊王建强西北大学大陆动力学国家重点实验室/地质学系/赵文智院士工作室陕西西安710069 低渗透油气田勘探开发国家工程实验室陕西西安710018 中国石油长庆油田分公司勘探开发研究院陕西西安710018

围绕鄂尔多斯盆地东南部中晚三叠世延长组物源演化,以盆地东南部韩城薛峰川地区延长组剖面为研究对象,运用碎屑锆石U-Pb年代学探讨了韩城地区延长期的物源特征。结果表明,韩城薛峰川地区延长组自下而上不同层段碎屑锆石U-Pb年龄谱峰特... 详细信息

围绕鄂尔多斯盆地东南部中晚三叠世延长组物源演化,以盆地东南部韩城薛峰川地区延长组剖面为研究对象,运用碎屑锆石U-Pb年代学探讨了韩城地区延长期的物源特征。结果表明,韩城薛峰川地区延长组自下而上不同层段碎屑锆石U-Pb年龄谱峰特征基本一致,峰值段主要集中在晚古生代晚期(250~263 Ma)、古元古宙晚期(1 689~1 774 Ma, 1 867~1 885 Ma)和古元古宙早期(2 490~2 560 Ma),太古宙年龄仅零星分布,而中新元古宙和早古生代年龄均缺失。综合物源对比认为,韩城地区延长期盆地物源主要来自于其东北部的华北克拉通内部及阴山造山带地区,而华北板块南缘及秦岭地区的南部物源特征不明显。这种物源特征与盆地西南部延长期物源复杂多变的特点形成了鲜明对比,表明鄂尔多斯盆地东南部延长期具有稳定的东北物源特征,推测其南地区在延长期仍存在分隔南部物源的深湖相沉积,该认识对探讨延长期湖盆演化具有重要意义。

关键词：鄂尔多斯盆地延长组碎屑锆石U-Pb年代学物源特征

Seedling growth and metal accumulation of selected woody species in copper and lead/zinc mine tailings

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Journal of Environmental Sciences 2011年第2期23卷 266-274页

作者： Xiang Shi xiaolei zhang Guangcai Chen Yitai Chen Ling Wang Xiaoquan Shan Research Institute of Subtropical Forestry Chinese Academy of Forestry Fuyang 311400 China College of Forestry Shandong Agricultural University Taian 271018 China College of Agronomy and Biotechnology Yunnan Agricultural University Kunming 650201 China State Key Laboratory of Environmental Chemistry and Ecotoxicology Research Center for Econvironmental Sciences Chinese Academy of Sciences Beijing 100085 China

A greenhouse pot experiment was conducted to evaluate the potential of selected woody plants for revegetation in copper （Cu） and lead/zinc （Pb/Zn） mine tailing areas. Five woody species （Amorpha fruticosa Linn, Vitex trifolia Linn. var. simplicifolia Chum, Glochidion puberum （Linn.） Hutch, Broussonetia papyrifera, and Styrax tonkinensis） and one herbaceous species （ Sesbania cannabina Pets） were planted in Cu and Pb/Zn tailings to assess their growth, root morphology, nutrition uptake, metal accumulation, and translocation in plants. Amorpha fruticosa maintained normal growth, while the other species demonstrated stress related growth and root development. Sesbania cannabina showed the highest biomass among the plants, although it decreased by 30% in Cu tailings and 40% in Pb/Zn railings. Calculated tolerance index （TI） values suggested that A. fruticosa, an N-fixing shrub, was the most tolerant species to both tailings （TI values 0.92-1.01）, while S. cannabina had a moderate TI of 0.65-0.81 and B. papyrifera was the most sensitive species, especially to Pb/Zn tailings （TI values 0.15-0.19）. Despite the high concentrations of heavy metals in the mine tailings and plants roots, only a small transfer of these elements to the aboveground parts of the woody plants was evident from the low translocation factor （TF） values. Among the woody plants, V. trifolia var. simplicifolia had the highest TF values for Zn （1.32）, Cu （0.78）, and Pb/Zn （0.78）. The results suggested that A. fruticosa and S. cannabina, which have the highest tolerance and biomass production, respectively, demonstrated the potential for tailings revegetation in southern China.

关键词： woody plants mine tailing tolerance revegetation root

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人文视域下的医学影像诊断学教学改革探索

中华诊断学电子杂志 2024年第3期12卷 188-192页

作者：林盼盼张晓磊吴仁华泉州医学高等专科学校临床医学院 362000 汕头大学医学院第二附属医院放射科 515041

目的将人文教学模式融入医学影像诊断学课程的教学中,探索人文教学模式的构建和应用效果。方法选择2022级泉州医学高等专科学校医学影像技术专业100名学生,采用抽签分组法,分为实验组(n=48)和对照组(n=52),实验组采用人文教学模式授课,... 详细信息

目的将人文教学模式融入医学影像诊断学课程的教学中,探索人文教学模式的构建和应用效果。方法选择2022级泉州医学高等专科学校医学影像技术专业100名学生,采用抽签分组法,分为实验组(n=48)和对照组(n=52),实验组采用人文教学模式授课,对照组采用传统教学模式授课。比较两组学生的理论考核成绩和学生互评分数,对实验组学生进行问卷调查并分析满意度。结果实验组学生的理论成绩[(81.73±3.19)分]高于对照组[(75.54±2.68)分],实验组学生的互评分数[(89.19±2.67)]分高于对照组[(74.02±8.21)分],均差异有统计学意义(t=5.25,7.41;均P<0.01)。问卷调查结果显示,83.33%(40/48)的学生对人文元素能够入脑入心的教学效果表示满意,97.92%(47/48)的学生对人文教学模式增强团队合作意识的教学效果表示满意。结论实施具有人文关怀特征的医学影像诊断学课程人文教学模式,可以提升医学生的学习效果和人文素养,值得进一步推广。

关键词：人文主义教育影像学学生,医科人文科学教学

Influence of tourist disturbance on soil properties, plant communities, and surface water quality in the Tianchi scenic area of Xinjiang, China

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Journal of Arid Land 2016年第2期8卷 304-313页

作者： WEN Bin zhang xiaolei YANG Zhaoping XIONG Heigang QIU Yang Xinjiang Institute of Ecology and Geography Chinese Academy of SciencesUrumqi 830011China College of Resource and Environment Sciences Xinjiang UniversityUrumqi 830046China University of Chinese Academy of Sciences Beijing 100049China Department of Economic Management Huanghuai UniversityZhumadian 463000China Cold and Arid Regions Environmental and Engineering Research Institute Chinese Academy of Sciences Lanzhou 730000China

The impact of tourist disturbance on the environment has become a focal issue of environmental science, ecology, and travel management studies. To assess the influence of tourist disturbance on soils and plants in the Tianchi scenic area of Xinjiang, China, we compared soil properties and plant community characteristics at 0, 5, 10, and 20 m from the tourist trail within areas at three different altitudes, where the intensities of tourist disturbance are distinct. Surface water quality was also studied at three different levels relative to the Tianchi Lake. The results showed that tourist disturbance significantly increased soil pH within 10 m from the trail and soil bulk density on the edge of the trail, but significantly reduced soil organic matter and total nitrogen contents within 5 m from the trail. The number of tree seedlings on the edge of the trail and the shrub coverage and height of herbaceous plants within 5 m from the trail significantly decreased due to tourist disturbance. Changes in herbaceous plant diversity differed by soil zones. In the high altitude region, tourist disturbance led to a remarkable increase in the herbaceous plant diversity on the edge of the trail, while in the low altitude region, tourist disturbance had a low impact on the diversity of herbaceous plants. In addition, tourist activities polluted the surface water, significantly reducing water quality. Thus, current tourist activities have a significant negative impact on the ecological environment in the Tianchi scenic area.

关键词： tourist disturbance soil properties plant communities water quality Tianchi scenic area

电针对帕金森病模型小鼠运动功能的影响及相关分子机制探讨

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北京中医药大学学报 2024年第5期47卷 721-728页

作者：祁羚李亚楠汪瑶张小蕾胡梦妮李含章肖蝶荣臻马骏湖北中医药大学针灸骨伤学院武汉430060 湖北时珍实验室

目的探究电针对帕金森病(PD)模型小鼠运动功能及中脑黑质NOD样受体热蛋白结构域相关蛋白3(NLRP3)炎性小体相关蛋白的影响。方法按照随机数字表法将C57BL/6小鼠分成对照组、模型组、电针组,每组12只。鱼藤酮溶液10 mg/(kg·d)灌胃小鼠... 详细信息

目的探究电针对帕金森病(PD)模型小鼠运动功能及中脑黑质NOD样受体热蛋白结构域相关蛋白3(NLRP3)炎性小体相关蛋白的影响。方法按照随机数字表法将C57BL/6小鼠分成对照组、模型组、电针组,每组12只。鱼藤酮溶液10 mg/(kg·d)灌胃小鼠模拟PD模型。造模后,电针组选取“风府”“太冲”“足三里”电针刺激,治疗2周;对照组和模型组为控制变量采取同一时间同步固定操作。采用行为学评分并运用旷场实验检测各组小鼠运动能力,免疫组化方法检测各组小鼠中脑黑质酪氨酸羟化酶(TH)和α-突触核蛋白(α-syn)表达,蛋白质印迹法检测小鼠中脑黑质NLRP3、胱天蛋白酶-1(Caspase-1)蛋白表达水平,酶联免疫吸附测定法检测各组小鼠中脑黑质白细胞介素-1β(IL-1β)含量。结果与对照组比较,模型组小鼠行为学评分升高(P200 mm/s)状态时间比降低(P<0.01);与模型组比较,电针组小鼠相对静止状态时间比降低(P<0.01),运动缓慢状态、快速运动状态时间比升高(P<0.01),运动速率提高。与对照组比较,模型组中脑黑质TH表达水平降低(P<0.01),α-syn表达水平升高(P<0.01);与模型组比较,电针组TH表达水平增加(P<0.05),α-syn表达水平降低(P<0.05)。与对照组比较,模型组中脑黑质NLRP3、Caspase-1蛋白表达增多(P<0.01);与模型组比较,电针组小鼠中脑黑质NLRP3、Caspase-1表达量减少(P<0.01)。与对照组比较,模型组小鼠中脑黑质IL-1β含量升高(P<0.01);与模型组比较,电针组IL-1β含量降低(P<0.05)。结论电针刺激“风府”“太冲”“足三里”能够有效减少PD标志物α-syn的异常聚集,增加TH表达量,改善PD模型小鼠的运动功能障碍,其分子机制可能与调控炎症小体相关通路NLRP3、Caspase-1、IL-1β表达有关。

关键词：帕金森病电针运动功能障碍风府太冲足三里小鼠

鄂尔多斯盆地马岭—乔川地区长6油层组油藏分布特征及控制因素

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成都理工大学学报（自然科学版） 2024年第3期51卷 379-391页

作者：刘志涛张晓磊田亚铭郭懿萱齐诗苇邵晓州成都理工大学地球与行星科学学院成都610059 中国石油长庆油田分公司勘探开发研究院西安710018 低渗透油气田勘探开发国家工程实验室西安710018

基于岩心观察、测井解释及开采数据分析,结合流体包裹体等测试,对马岭—乔川地区长6油层组的油藏分布特征及控制因素开展研究。研究结果表明,研究区油藏纵向上主要分布在长63油层段,长62、长61油层段含油性显著变差;平面上,长63油层段以... 详细信息

基于岩心观察、测井解释及开采数据分析,结合流体包裹体等测试,对马岭—乔川地区长6油层组的油藏分布特征及控制因素开展研究。研究结果表明,研究区油藏纵向上主要分布在长63油层段,长62、长61油层段含油性显著变差;平面上,长63油层段以L125,B452和L411井区为中心,油藏团块状分布,呈两条带沿北西南东向延伸,油层厚度主要在5~20 m之间,长62、长61油层呈孤立土豆疙瘩状分布,分布规模小。长6油层组油藏以岩性油藏为主,包裹体均一温度集中在70~90℃,荧光以黄褐色为主,结合区域埋藏史分析显示该区油藏充注为晚侏罗世和中-晚白垩世,表现为早期充注。长6油层组烃源岩厚度、距离,砂体砂质碎屑流砂体性质、物性和叠置类型是其形成油气藏的重要影响因素;长63油层段相比长62和长61油层段具有更靠近烃源岩,砂质碎屑流成因砂体分布广、孔渗条件好、叠置厚层砂体类型发育等优势。研究区最为有利油藏的勘探目标为长63油层段Y470,L374,B452等井区附近,有利勘探区面积达到517.28 km 2。

关键词：马岭—乔川地区长6油层组油藏分布控制因素有利区预测

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基于扰动观测的小型反作用飞轮高精度控制

电子技术应用 2024年第7期50卷 65-70页

作者：沈莹张晓磊孔令波胡慧莹长光卫星技术股份有限公司吉林长春130000

反作用飞轮是卫星姿态控制系统的关键部件,其性能指标直接关系到光学遥感卫星的控制精度。为了实现高精度的反作用飞轮转速控制,提出了一种基于扰动观测器的非线性控制方法。首先,建立了基于无刷直流电机的反作用飞轮数学模型,分析了影... 详细信息

反作用飞轮是卫星姿态控制系统的关键部件,其性能指标直接关系到光学遥感卫星的控制精度。为了实现高精度的反作用飞轮转速控制,提出了一种基于扰动观测器的非线性控制方法。首先,建立了基于无刷直流电机的反作用飞轮数学模型,分析了影响转速控制精度的因素,并构建了用于控制器设计的非线性模型。然后,结合扰动观测器和非线性控制理论设计了基于扰动观测的非线性控制器,并利用李雅普诺夫理论证明了控制方法的稳定性。最后,通过数值仿真证明飞轮转速可以平稳达到控制目标值,精度优于传统的PI控制方法,并在飞轮实体上验证了本文方法的有效性。

关键词：反作用飞轮无刷直流电机干扰观测器非线性控制器

Temporal and spatial responses of ecological resilience to climate change and human activities in the economic belt on the northern slope of the Tianshan Mountains, China

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干旱区科学:英文版 2023年第10期15卷 1245-1268页

作者： zhang Shubao LEI Jun TONG Yanjun zhang xiaolei LU Danni FAN Liqin DUAN Zuliang State Key Laboratory of Desert and Oasis Ecology/Key Laboratory of Ecological Safety and Sustainable Development in Arid Lands Xinjiang Institute of Ecology and GeographyChinese Academy of SciencesUrumqi 830011China University of Chinese Academy of Sciences Beijing 100049China Institute of Geology and Geophysics Chinese Academy of SciencesBeijing 100029China

In the Anthropocene era,human activities have become increasingly complex and *** natural ecosystems need higher ecological resilience to ensure regional sustainable development due to rapid urbanization and industrialization as well as other intensified human activities,especially in arid and semi-arid *** the study,we chose the economic belt on the northern slope of the Tianshan Mountains(EBNSTM)in Xinjiang Uygur Autonomous Region of China as a case *** collecting geographic data and statistical data from 2010 and 2020,we constructed an ecological resilience assessment model based on the ecosystem habitat quality(EHQ),ecosystem landscape stability(ELS),and ecosystem service value(ESV).Further,we analyzed the temporal and spatial variation characteristics of ecological resilience in the EBNSTM from 2010 to 2020 by spatial autocorrelation analysis,and explored its responses to climate change and human activities using the geographically weighted regression(GWR)*** results showed that the ecological resilience of the EBNSTM was at a low level and increased from 0.2732 to 0.2773 during 2010–*** spatial autocorrelation analysis of ecological resilience exhibited a spatial heterogeneity characteristic of"high in the western region and low in the eastern region",and the spatial clustering trend was enhanced during the study ***,Gobi and rapidly urbanized areas showed low level of ecological resilience,and oasis and mountain areas exhibited high level of ecological *** factors had an important impact on ecological ***,average annual temperature and annual precipitation were the key climate factors that improved ecological resilience,while average annual evapotranspiration was the main factor that blocked ecological *** the human activity factors,the distance from the main road showed a negative correlation with ecological *** night light index and PM2.5 concentration wer

关键词： ecological resilience ecosystem habitat quality ecosystem landscape stability ecosystem service value spatial autocorrelation analysis geographically weighted regression model economic belt on the northern slope of the Tianshan Mountains