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数字新质生产力、现代产业体系构建与共同富裕

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工业技术经济 2024年第6期43卷 20-29页

作者：高小涵王立娟大连理工大学高等教育研究院大连116024 大连科技学院信息科学与技术学院大连116052

本文立足现代产业体系构建视角,在系统梳理数字新质生产力对共同富裕影响及作用机制的理论基础上,利用2012~2022年我国30个省级面板数据展开实证分析。研究表明:数字新质生产力可显著推动共同富裕,该结论经过诸多内生性及稳健性检验后... 详细信息

本文立足现代产业体系构建视角,在系统梳理数字新质生产力对共同富裕影响及作用机制的理论基础上,利用2012~2022年我国30个省级面板数据展开实证分析。研究表明:数字新质生产力可显著推动共同富裕,该结论经过诸多内生性及稳健性检验后依旧成立;作用机制分析发现,现代产业体系构建是数字新质生产力赋能共同富裕的重要中介渠道;异质性分析表明,在高科技创新水平地区和东部地区,数字新质生产力对共同富裕的推动作用更强。根植于此,提出应强化数字赋能,提升数字新质生产力水平;推动产业转型,加快构建现代产业体系;实施差异战略,加快缩小区域经济差距。

关键词：共同富裕数字新质生产力现代产业体系构建科技创新产业转型差异战略

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基于生命周期评价的秸秆发电供应链模式研究

河南农业大学学报 2024年第4期58卷 663-673页

作者：张红阳高小涵王恒王占武曲青青河南农业大学机电工程学院河南郑州450002 农产品冷链物流信息与装备技术河南省工程实验室河南郑州450002

【目的】评估不同秸秆发电供应链模式的碳减排潜力,探究影响碳减排能力的因素。【方法】采用生命周期评价方法,对秸秆发电不同阶段的污染物排放进行分析,并建立秸秆发电供应链系统的碳减排评估模型,计算不同模式下污染物的排放量和碳减... 详细信息

【目的】评估不同秸秆发电供应链模式的碳减排潜力,探究影响碳减排能力的因素。【方法】采用生命周期评价方法,对秸秆发电不同阶段的污染物排放进行分析,并建立秸秆发电供应链系统的碳减排评估模型,计算不同模式下污染物的排放量和碳减排量。【结果】秸秆发电供应链的运输和发电利用阶段是污染物的主要排放源,其中污染物PM10、SO_(2)、CH_(4)、CO主要来源于发电阶段,所占比例分别为97%、93%、98%和76%;CO_(2)主要来源于运输阶段,所占比例为80%。4种秸秆发电供应链模式的碳减排量分别为5995.16、6076.57、6121.73和6125.68 kg。【结论】秸秆发电供应链模式的选用对系统碳减排能力有较大影响,在不同背景下选择合适的供应链模式可以减少碳排放。通过对秸秆发电供应链碳排放结果的灵敏度分析可以发现,秸秆收集半径、运输工具油耗、化肥农药使用量和除尘技术等因素对碳排放有显著的影响。

关键词：秸秆发电生命周期评价供应链碳减排

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中医各家学说教学中以学生为中心的小组合作学习研究

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中国中医药现代远程教育 2024年第16期22卷 47-50页

作者：张俐敏高晓涵黄益清马丽山西中医药大学基础医学院山西晋中030619

中医各家学说是教育部高等学校中医学类专业教学指导委员会高等学校中医类专业核心课程之一,既是一门大学本科中医专业后期理论提高课,又是一门必修的临床基础课,在中医基础课程和临床课程知识综合准备应用于临床的能力培养中必不可少... 详细信息

中医各家学说是教育部高等学校中医学类专业教学指导委员会高等学校中医类专业核心课程之一,既是一门大学本科中医专业后期理论提高课,又是一门必修的临床基础课,在中医基础课程和临床课程知识综合准备应用于临床的能力培养中必不可少。文章基于传统课堂模式的不足和教学改革现状,提出以学生为中心的自主学习课程模式,并以分组学习为特色。教师按成绩水平分组,每组内包含好、中、差三等的学生,小组内接到任务后进行分组讨论学习,任务完成后让组内知识相对薄弱的学生汇报小组成果,所得成绩为组内所有成员的成绩,使得优等生更愿意帮助差等生学习,从而推动各层次学生中医经典著作的自主学习和中医临床思维能力的培养。

关键词：中医各家学说自主学习分组学习兵教兵临床思维能力培养

Recent advances for liquid metals:Synthesis,modification and bio-applications

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Journal of Materials Science & Technology 2023年第12期143卷 153-168页

作者： Zhenhu Guo xiaohan gao Jingsong Lu Wanling Xu Jielin Ye Ying Li Wensheng Xie Lingyun Zhao Key Laboratory of Advanced Materials Ministry of Education of ChinaSchool of Materials Science and EngineeringTsinghua UniversityBeijing 100084China State Key Laboratory of New Ceramics and Fine Processing School of Materials Science and EngineeringTsinghua UniversityBeijing 100084China School of Medicine Tsinghua UniversityBeijing 100084China Department of Neurosurgery Yuquan HospitalSchool of Clinical MedicineTsinghua UniversityBeijing 100084China The Key Laboratory of Bioorganic Phosphorus Chemistry&Chemical Biology(Ministry of Education) Department of ChemistryTsinghua UniversityBeijing 100084China

Considering the application requirements for modern biomedicine,research into novel biomaterials with unusual functions is highly *** an alternative,liquid metals(LMs),a nontraditional family of metal materials,have piqued the interest of biomedical researchers and made significant advances in biomed-ical areas,owing to their shape transformability,self-healing capability,excellent electrical,and thermal *** particular,many functionalized strategies for the preparation and modification of LMs or LMs-based composites to achieve extended biomedical applications have been investigated in recent *** findings provided inspiring while constructive reference for the fabrication and engineering of novel LMs-based ***,in this topic review,we elaborate on the recent advances of LMs-based functional materials,with particular focuses on the synthesis,modification,and bio-applications,especially in antitumor therapy,antibacterial,contrast agent for imaging,bone repair,electronic skin sen-sor,and nerve connection *** on,the current challenges and future prospects of LMs-based composites are carefully discussed.

关键词： Liquid metals Synthesis Composites Antitumor therapy Bio-application

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钒氧化物及金属钒酸盐在化学储能中的应用

石油学报（石油加工） 2024年第4期40卷 1061-1071页

作者：关尹宁高肖汉张晓帆李霞柯越张雅琦吕雪川辽宁石油化工大学石油化工学院辽宁抚顺113001 中国石油辽阳石化分公司辽宁辽阳111003

钒氧化物具有多变的配位数和氧化态、较低的成本、丰富的资源等优点,作为典型的过渡金属氧化物,其应用于锂离子电池电极材料时具有良好的锂离子存储能力和较强的循环能力。钒氧化物在超级电容器中表现出高功率密度、快速充放电率和优良... 详细信息

钒氧化物具有多变的配位数和氧化态、较低的成本、丰富的资源等优点,作为典型的过渡金属氧化物,其应用于锂离子电池电极材料时具有良好的锂离子存储能力和较强的循环能力。钒氧化物在超级电容器中表现出高功率密度、快速充放电率和优良的循环周期等特性,是一种理想的储能材料,而金属钒酸盐显示出良好的可逆性和循环性。构筑合理纳米结构是获得电化学性能优异钒氧化物电极材料的有效途径,是提高电极材料放电/充电效率的最有效方法之一。综述了钒氧化物和金属钒酸盐在锂离子电池中应用以及钒氧化物在超级电容器中应用的研究进展,讨论了结构、制备条件对钒氧化物及金属钒酸盐性能的影响,展望了钒氧化物及金属钒酸盐的应用前景。

关键词：锂离子电池超级电容器钒氧化物金属钒酸盐电化学性能化学储能钒基电极

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Milk fat globule membrane supplementation protects againstβ-lactoglobul-ininduced food allergy in mice via upregulation of regulatory T cells and enhancement of intestinal barrier in a microbiota-derived short-chain fatty acids manner

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Food Science and Human Wellness 2024年第1期13卷 124-136页

作者： Han Gong Tiange Li Dong Liang Jingxin gao xiaohan Liu Xueying Mao Key Laboratory of Functional Dairy Ministry of EducationCollege of Food Science and Nutritional EngineeringChina Agricultural UniversityBeijing 100083China Henan Engineering Technology Research Center of Food Processing and Circulation Safety Control College of Food Science and TechnologyHenan Agricultural UniversityZhengzhou 450002China Applied Nutrition I China National Center for Food Safety Risk AssessmentBeijing 100022China

Milk fat globule membrane(MFGM),which contains abundant glycoproteins and phospholipids,exerts beneficial effects on intestinal health and *** aim of this study was to evaluate the protective effects and possible underlying mechanisms of MFGM on cow’s milk allergy(CMA)in aβ-lactoglobulin(BLG)-induced allergic mice *** was supplemented to allergic mice induced by BLG at a dose of 400 mg/kg body *** demonstrated that MFGM alleviated food allergy symptoms,decreased serum levels of lipopolysaccharide,pro-inflammatory cytokines,immunoglobulin(Ig)E,Ig G1,and Th2 cytokines including interleukin(IL)-4,while increased serum levels of Th1 cytokines including interferon-γand regulatory T cells(Tregs)cytokines including IL-10 and transforming growth factor-β.MFGM modulated gut microbiota and enhanced intestinal barrier of BLG-allergic mice,as evidenced by decreased relative abundance of Desulfobacterota,Rikenellaceae,Lachnospiraceae,and Desulfovibrionaceae,while increased relative abundance of Bacteroidetes,Lactobacillaceae and Muribaculaceae,and enhanced expressions of tight junction proteins including Occludin,Claudin-1 and zonula ***,MFGM increased fecal short-chain fatty acids(SCFAs)levels,which elevated G protein-coupled receptor(GPR)43 and GPR109A *** increased expressions of GPR43 and GPR109A induced CD103+dendritic cells accumulation and promoted Tregs differentiation in mesenteric lymph node to a certain *** summary,MFGM alleviated CMA in a BLG-induced allergic mice model through enhancing intestinal barrier and promoting Tregs differentiation,which may be correlated with SCFAs-mediated activation of *** findings suggest that MFGM may be useful as a promising functional ingredient against CMA.

关键词： Cow’s milk allergy Milk fat globule membrane Gut microbiota Short-chain fatty acid G protein-coupled receptor Regulatory T cell

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超大规格2024铝合金扁锭开裂行为研究

轻合金加工技术 2024年第5期52卷 7-16页

作者：韩再旭高晓晗刘学吴永福余康才王国军东北轻合金有限责任公司黑龙江哈尔滨150060 中铝材料应用研究院有限公司北京102209 北京科技大学北京100083

随着航空航天大型结构件尺寸的增大,高强铝合金铸锭的尺寸也要增大,铸锭成型难度也随之增大。通过铸造过程数值模拟研究了铸造速度和刮水器位置对500 mm×2300 mm和600 mm×2500 mm规格2024铝合金扁铸锭温度场及应力场的影响规律。结果... 详细信息

随着航空航天大型结构件尺寸的增大,高强铝合金铸锭的尺寸也要增大,铸锭成型难度也随之增大。通过铸造过程数值模拟研究了铸造速度和刮水器位置对500 mm×2300 mm和600 mm×2500 mm规格2024铝合金扁铸锭温度场及应力场的影响规律。结果表明,铸造速度对液穴深度影响最大,提升铸造速度能够大幅降低铸锭内应力,但是大幅增加了液穴深度,不利于减轻铸锭疏松和热裂;提升刮水器位置可以大幅降低铸锭的应力。提出了降低铸造速度的同时提升刮水器位置的工艺优化方向,该工艺可以制备超大规格2024铝合金扁铸锭。

关键词：铝合金半连续铸造热应力冷裂液穴深度

Structure and immunomodulatory activity of Lentinus edodes polysaccharides modified by probiotic fermentation

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Food Science and Human Wellness 2024年第1期13卷 421-433页

作者： Jingjing Liang Meina Zhang xiaohan Li Yuan Yue Xiaowei Wang Mengzhen Han Tianli Yue Zhouli Wang Zhenpeng gao College of Food Science and Engineering Northwest A&F UniversityYangling 712100China Xi'an gaoXin No.1 High School Xi'an 710065China

Plant-based fermentations provide an untapped source for novel biotechnological *** this study,a probiotic named Lactobacillus fermentum 21828 was introduced to ferment Lentinus *** were extracted from fermented and non-fermented *** and purified via DEAE-52 and Sephadex *** components designated F-LEP-2a and NF-LEP-2a were analyzed by FT-IR,HPGPC,HPAEC,SEM,GC-MS and *** results revealed that probiotic fermentation increased the molecular weight from 1.16×10^(4) Da to 1.87×10^(4) Da and altered the proportions of glucose,galactose and mannose,in which glucose increased from 45.94%to 48.16%.Methylation analysis and NMR spectra indicated that F-LEP-2a and NF-LEP-2a had similar linkage ***,their immunomodulatory activities were evaluated with immunosuppressive ***-LEP and F-LEP improved immune organ indices,immunoglobulin(Ig G and Ig M)and cytokines concentrations;restored the antioxidation capacity of liver;and maintained the balance of gut microbiota.F-LEP displayed better moderating effects on the spleen index,immunoglobulin,cytokines and the diversity of gut microbiota than NF-LEP(200,400 mg/kg).Our study provides an efficient and environment-friendly way for the structural modification of polysaccharides,which helps to enhance their biological activity and promote their wide application in food,medicine and other fields.

关键词： Lentinus edodes polysaccharide Lactobacillus fermentum fermentation Structural analysis Immunoregulatory activity Nuclear magnetic resonance

Crosstalk between PC 12 cells and endothelial cells in an artificial neurovascular niche constructed by a dual-functionalized selfassembling peptide nanofiber hydrogel

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Nano Research 2022年第2期15卷 1433-1445页

作者： Zhe Zhang Yi Chai He Zhao Shuhui Yang Wei Liu Zihui Yang Weilong Ye Chenlong Wang xiaohan gao Xiangdong Kong Xiaodan Sun Lingyun Zhao Tuoyu Chen Yuqi Zhang Jiaju Lu Xiumei Wang State Key Laboratory of New Ceramics and Fine Processing School of Materials Science and EngineeringTsinghua UniversityBeijing 100084China Department of Neurosurgery Yuquan HospitalSchool of Clinical MedicineTsinghua UniversityBeijing 100084China Institute of Smart Biomedical Materials School of Materials Science and EngineeringZhejiang Sci-Tech UniversityHangzhou 310018China Department of orthopedics Dongzhimen hospitalBeijing University of Chinese MedicineBeijing 100700China Department of Neurosurgery The First Hospital of Hebei Medical UniversityShijiazhuang 050000China Department of Obstetrics and Gynecology Beijing Tsinghua Changgung HospitalBeijing 102218China Department of Chemistry Tsinghua UniversityBeijing 100084China

The coordination between neurogenesis and angiogenesis plays an important role in nerve tissue development and ***,using bioactive materials to drive neurogenic and angiogenic responses has gained increasing *** the neurovascular link between regulatory cues offers valuable insight into the mechanisms underlying nerve regeneration and the design of new bioactive *** this study,we utilized a dual-functionalized peptide nanofiber hydrogel presenting the brain-derived neurotrophic factor and vascular endothelial growth factor mimetic peptides RGIDKRHWNSQ(RGI)and KLTWQELYQLKYKGI(KLT)to construct an artificial neurovascular *** dual-functionalized peptide nanofiber hydrogel enhanced the neurite outgrowth of pheochromocytoma(PC12)cells and tube-like structures formation of human umbilical vein endothelial cells(HUVECs)in vitro,and promoted rapid lesion infiltration of neural and vascular cells in a rat brain injury *** indirect co-culture models,we found that the dual-functionalized peptide hydrogel effectively mediated neurovascular crosstalk by regulating secretion of paracrine factors from PC12 cells and *** the two cells types were directly co-cultured on the dua卜functionalized peptide hydrogel,the efficiency of cell-cell communication was enhanced,which further accelerated the differentiation and maturation of PC12 cells with an increased number of pseudopodia and spread morphology,and HUVECs tube-like structure *** summary,the dual-functionalized peptide nanofiber hydrogel successfully formed an artificial neurovascular niche to directly regulate the behaviors of neural and vascular cells and promote their neurovascular crosstalk through paracrine signaling and direct cell-cell contact.

关键词： neurovascular microenvironment self-assembling peptide co-culture nanofiber hydrogel brain injury