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JAPO: learning join and pushdown order for cloud-native join optimization

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Frontiers of Computer Science 2024年第6期18卷 186614-186614页

作者： YUAN Yuchen feng xiaoyue ZHANG Bo ZHANG Pengyi SONG Jie Software College Northeastern University

In this paper, we introduce JAPO which learn the join and pushdown order through DRL. The main idea is that the DRL agent learns better decisions based on the experiences by monitoring the rewards and latencies via trying different actions. The results show that our method can generate good plans both on join order and pushdown order. We also show that our method can select the well-performed distributed index placement via experiments. In the future, we plan to deploy JAPO to real systems execution and consider more factors in JAPO, such as different join types.

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SEOE: an option graph based semantically embedding method for prenatal depression detection

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Frontiers of Computer Science 2024年第6期18卷 186911-186911页

作者： HAN Xiaosong CAO Mengchen XU Dong feng xiaoyue LIANG Yanchun LANG Xiaoduo GUAN Renchu College of Computer Science and Technology Key Laboratory of Symbolic Computation and Knowledge Engineering of Ministry of Education Jilin University Department of Electrical Engineering and Computer Science and Christopher S. Bond Life Sciences Center University of Missour Department of Computer Science and Technology Zhuhai Laboratory of Key Laboratory of Symbolic Computation and Knowledge Engineering of Ministry of Education Zhuhai College of Science and Technology Jilin Provincial Institute of Population Science and Technology

Prenatal depression, which can affect pregnant women’s physical and psychological health and cause postpartum depression, is increasing dramatically. Therefore, it is essential to detect prenatal depression early and conduct an attribution analysis. Many studies have used questionnaires to screen for prenatal depression, but the existing methods lack attributability. To diagnose the early signs of prenatal depression and identify the key factors that may lead to prenatal depression from questionnaires, we present the semantically enhanced option embedding (SEOE) model to represent questionnaire options. It can quantitatively determine the relationship and patterns between options and depression. SEOE first quantifies options and resorts them, gathering options with little difference, since Word2Vec is highly dependent on context. The resort task is transformed into an optimization problem involving the traveling salesman problem. Moreover, all questionnaire samples are used to train the options’ vector using Word2Vec. Finally, an LSTM and GRU fused model incorporating the cycle learning rate is constructed to detect whether a pregnant woman is suffering from depression. To verify the model, we compare it with other deep learning and traditional machine learning methods. The experiment results show that our proposed model can accurately identify pregnant women with depression and reach an F1 score of 0.8. The most relevant factors of depression found by SEOE are also verified in the literature. In addition, our model is of low computational complexity and strong generalization, which can be widely applied to other questionnaire analyses of psychiatric disorders.

关键词： questionnaire analyses text classification graph representation learning traveling salesman problem prenatal depression

Mid-infrared SESAM mode-locked Er:CaF_(2)-SrF_(2)bulk laser at 2.73µm

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Chinese Optics Letters 2024年第5期22卷 85-88页

作者：刘晶晶唐琳萱冯潇玥宗梦雨仝鲁阳张振赵丽娜刘杰苏良碧 Shandong Provincial Engineering and Technical Center of Light Manipulations and Shandong Provincial Key Laboratory of Optics and Photonic Device School of Physics and ElectronicsShandong Normal UniversityJinan 250358China CAS Key Laboratory of Transparent and Opto-Functional Inorganic Materials Synthetic Single Crystal Research CenterShanghai Institute of CeramicsChinese Academy of SciencesShanghai 201899China State Key Laboratory of High Performance Ceramics and Superfine Microstructure Shanghai Institute of CeramicsChinese Academy of SciencesShanghai 201899China

To the best of our knowledge,this is the first time that a mid-infrared Er^(3+):CaF_(2)-SrF_(2) laser has achieved continuous-wave mode-locked operation by a semiconductor saturable absorber *** laser emits a maximum output power of 93 mW at 2.73μm with a repetition rate of approximately 69 MHz and demonstrates a high signal-to-noise ratio of around 71 *** addition,a MgF_(2) birefringent plate was utilized to enable wavelength tuning of the Er^(3+):CaF_(2)-SrF_(2) laser,resulting in operation at approximately 2.73μm,2.75μm,2.79μm,and 2.81μ*** results demonstrate that Er^(3+):CaF_(2)-SrF_(2) is a promising alternative for the generation of efficient diode-pumped mode-locked lasers around 2.8μm.

关键词： mid-infrared laser mode-locked laser tunable wavelength

Multi-Agent Deep Reinforcement Learning for Efficient Computation Offloading in Mobile Edge Computing

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Computers, Materials & Continua 2023年第9期76卷 3585-3603页

作者： Tianzhe Jiao xiaoyue feng Chaopeng Guo Dongqi Wang Jie Song Department of Software Engineering Software CollegeNortheastern UniversityShenyang110819China

Mobile-edge computing(MEC)is a promising technology for the fifth-generation(5G)and sixth-generation(6G)architectures,which provides resourceful computing capabilities for Internet of Things(IoT)devices,such as virtual reality,mobile devices,and smart *** general,these IoT applications always bring higher energy consumption than traditional applications,which are usually *** provide persistent energy,many references have studied the offloading problem to save energy ***,the dynamic environment dramatically increases the optimization difficulty of the offloading *** this paper,we aim to minimize the energy consumption of the entireMECsystemunder the latency constraint by fully considering the dynamic *** games,we propose amulti-agent deep reinforcement learning approach based on the bi-level actorcritic learning structure to jointly optimize the offloading decision and resource allocation,which can solve the combinatorial optimization problem using an asymmetric method and compute the Stackelberg equilibrium as a better convergence point than Nash equilibrium in terms of Pareto *** method can better adapt to a dynamic environment during the data transmission than the single-agent strategy and can effectively tackle the coordination problem in the multi-agent *** simulation results show that the proposed method could decrease the total computational overhead by 17.8%compared to the actor-critic-based method and reduce the total computational overhead by 31.3%,36.5%,and 44.7%compared with randomoffloading,all local execution,and all offloading execution,respectively.

关键词： Computation offloading multi-agent deep reinforcement learning mobile-edge computing latency energy efficiency

High repetition rate passively Q-switched laser on Nd:SRA at 1049 nm with MXene Ti3C2Tx

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Chinese Optics Letters 2020年第4期18卷 17-20页

作者： Mengfei Zhao Zhongmian Zhang xiaoyue feng Mengyu Zong Jie Liu Xiaodong Xu Han Zhang Shandong Provincial Engineering and Technical Center of Light Manipulations&Shandong Provincial Key Laboratory of Optics and Photonic Device School of Physics and ElectronicsShandong Normal UniversityJinan 250358China Jiangsu Key Laboratory of Advanced Laser Materials and Devices School of Physics and Electronic EngineeringJiangsu Normal UniversityXuzhou 221116China Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province College of Electronic Science and Technology and College of Optoelectronics EngineeringShenzhen UniversityShenzhen 518060China

A new disordered crystal Nd:SrAl12O19(Nd:SRA)with an Nd3+doping concentration of 5%was successfully grown using the Czochralski method.A diode-pumped Nd:SRA Q-switched laser operating at 1049 nm was demonstrated for the first time,to the best of our *** on an MXene Ti3C2Tx sheet,a high repetition rate of 201 kHz and a Q-switched pulse width of 346 ns were obtained when the absorbed pump power was 2.8 *** peak power and single pulse energy were 1.87 W and 0.65μJ,respectively.

关键词： Nd:SrAl12O19 crystal MXene Ti3C2Tx disordered crystal passively Q-switched lasers

Ag-doped Ti_(3)C_(2)T_(x) sensor:A promising candidate for lowconcentration H_(2)S gas sensing

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High Voltage 2024年第3期9卷 537-545页

作者： Fuping Zeng Xiaoxuan feng xiaoyue Chen Hao Qiu Yiming Yan Qiang Yao Ju Tang School of Electrical Engineering and Automation Wuhan UniversityWuhanChina Hubei Key Laboratory of Power Equipment&System Security for Integrated Energy Resources WuhanChina State Grid Chengdu Electric Power Supply Company ChengduChina State Grid Chongqing Electric Power Research Institute ChongqingChina State Key Laboratory of Power Transmission Equipment&System Security and New Technology Chongqing UniversityChongqingChina

Trace hydrogen sulphide(H_(2)S)could reflect the severity of insulation faults in gas-insulated switchgear(GIS),therefore,accurate and fast detection of low-concentration H_(2)S is important for on-line monitoring,fault diagnosis,and state evaluation in ***-Ti_(3)C_(2)T_(x) chemiresistive-type sensors were fabricated via drop-coating with self-reduction synthesised Ag-doped Ti_(3)C_(2)T_(x).The as-prepared sensors exhibited an excel-lent sensitivity and selectivity to H_(2)S with an extremely low detection of limit of 18.57 parts per billion(ppb)at 25℃(room temperature).The response of Ag-Ti_(3)C_(2)T_(x) sensor to 10 parts per million(ppm)H_(2)S was enhanced~12 times than that of the pristine Ti_(3)C_(2)T_(x) *** compositing of Ti_(3)C_(2)T_(x) with Ag nanoparticles(NPs)enabled the fast response/recovery time for H_(2)S *** analysis found that the enhanced H_(2)S sensing performances could be attributed to chemical sensitisation,adsorbed oxygen species regulation and high Brunauer–Emmett–Teller(BET)surface *** study paves the way for Ag-Ti_(3)C_(2)T_(x) as room-temperature sensing materials to detect low-concentration H_(2)S in GIS.

关键词： insulation diagnosis attributed

Bone marrow mesenchymal stem cell-induced autophagy ameliorates TNBS-induced experimental colitis by downregulating the NLRP3 inflammasome

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BIOCELL 2023年第12期47卷 2627-2639页

作者： JINJIN FU xiaoyue feng JUAN WEI XIANG GENG YU GONG fengDONG LI SHAOHUA ZHUANG JIN HUANG FANGYU WANG Department of Gastroenterology The Affiliated Changzhou No.2 People’s HospitalNanjing Medical UniversityChangzhouChina Department of Gastroenterology Jinling HospitalNanjing Medical UniversityNanjingChina

This study aimed to elucidate the potential mechanisms through which bone marrow-derived mesenchymal stem cells(BM-MSCs)may be effective in alleviating experimental colitis induced by treatment with 2,4,6-trinitrobenzene-sulfonate acid(TNBS),specifically through autophagy ***:BM-MSCs were collected from BALB/c mice for subsequent *** study employed cell counting kits(CCK-8)to investigate the impact of the MSC-conditioned medium(M medium)on the proliferation of RAW264.7 *** GFP-mRFP-LC3 adenovirus was transfected into RAW264.7 to detect autophagic *** gene expression of cytokines was assessed through quantitative reverse transcription polymerase chain reaction(qRT-PCR).Western blot analysis was employed to determine the presence of a binding interaction between NOD-like receptor protein 3(NLRP3)and ***,a colitis mouse model was established by TNBS *** disease activity score was assessed regularly,and histological and morphometric analyses were performed on colonic *** serum cytokines were identified using an enzyme-linked immunosorbent ***:BM-MSCs significantly promoted the proliferation of *** vitro lipopolysaccharide(LPS)-stimulated RAW264.7 cells,treated with BM-MSCs,triggered autophagy and inhibited cytokine mRNA ***,in LPS-induced RAW264.7,BM-MSCs enhanced the Beclin1 protein expression and the microtubule-associated protein 1 light chain 3(LC3)-II to LC3-I ratio while suppressing the protein levels of NLRP3 and apoptosis-associated speck-like protein(ASC).Nevertheless,3-methyladenine(3-MA),an inhibitor of autophagy,prevented the impact of BM-MSCs by reducing the levels of NLRP3 and ASC proteins,suggesting that autophagy triggered the inhibition of the NLRP3 *** comparison to the mice in the TNBS group,the mice in the TNBS+MSC group displayed a more acute form of colitis,and the IL1βand IL18 cytokines in their serum were

关键词： RAW264.7 3-Methyladenine(3-MA) IL1β IL18

CT引导下脉冲射频联合臭氧注射治疗带状疱疹相关性疼痛患者的疗效及安全性

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中华疼痛学杂志 2024年第2期20卷 223-230页

作者：王祥霍建忠王奇冯晓月张文静赵一帆陈建平山西医科大学第三医院山西白求恩医院疼痛科太原市030032 山西医科大学附属太原中心医院太原市中心医院骨科太原市030006

目的评价CT引导下脉冲射频联合臭氧注射治疗带状疱疹相关性疼痛的临床疗效及安全性。方法回顾性分析2019年1月1日至2021年12月30日,在山西白求恩医院疼痛科行脉冲射频联合臭氧注射治疗的带状疱疹相关性疼痛患者84例,性别、年龄不限。根... 详细信息

目的评价CT引导下脉冲射频联合臭氧注射治疗带状疱疹相关性疼痛的临床疗效及安全性。方法回顾性分析2019年1月1日至2021年12月30日,在山西白求恩医院疼痛科行脉冲射频联合臭氧注射治疗的带状疱疹相关性疼痛患者84例,性别、年龄不限。根据病程持续时间不同将患者分为3组:急性带状疱疹性神经痛组(AHN组,≤30 d,28例)、亚急性带状疱疹性神经痛组(SHN组,>30~90 d,32例)、带状疱疹后神经痛组(PHN组,>90 d,24例)。比较3组患者基线资料,收集并比较患者治疗前、治疗后当日及治疗后1、3、6和12个月的视觉模拟评分(VAS)、匹兹堡睡眠质量指数(PSQI)及普瑞巴林日用量。比较3组患者治疗后1、3、6和12个月时药物补救使用率、治疗无效率及不良反应情况。结果3组患者一般资料中病程比较差异有统计学意义(P0.05)。与治疗前比较,3组患者治疗后各时点VAS、PSQI评分及普瑞巴林日用量均降低(P均<0.05)。与PHN组比较,AHN组和SHN组患者治疗后各时点VAS、PSQI评分及普瑞巴林日用量更低(P均<0.05)。AHN组和SHN组患者治疗后1、3、6、12个月时药物补救使用率比PHN组更低[(14.3%、14.3%、10.7%、3.6%)和(15.6%、15.6%、12.5%、6.3%)比(45.8%、41.7%、37.5%、25.0%),χ^(2)组间=9.04,P组间<0.001]。AHN组和SHN组患者治疗后1、3、6、12个月时无效率比PHN组更低[(7.1%、7.1%、7.1%、7.1%)和(6.3%、9.4%、9.4%、9.4%)比(29.2%、33.3%、29.2%、29.2%),χ^(2)组间=23.59,P组间=0.011]。3组患者均无严重不良反应发生。结论CT引导下脉冲射频联合臭氧注射治疗带状疱疹相关性疼痛患者安全有效,近期和远期疗效显著,但早期脉冲射频联合臭氧注射临床效果更佳。

关键词：臭氧射频疗法带状疱疹相关性疼痛疗效

STAT3 ameliorates truncated tau-induced cognitive deficits

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Neural Regeneration Research 2024年第4期19卷 915-922页

作者： Bingge Zhang Huali Wan Maimaitijiang Maierwufu Qian Liu Ting Li Ye He Xin Wang Gongping Liu xiaoyue Hong Qiong feng Department of Pathophysiology School of Basic Medicine and the Collaborative Innovation Center for Brain ScienceKey Laboratory of Ministry of Education of China and Hubei Province for Neurological DisordersTongji Medical CollegeHuazhong University of Science and Technology Department of Laboratory Medicine Guangdong ProvincialPeople's Hospital(Guangdong Academy of Medical Sciences)Southern Medical University Department of Laboratory Medicine Zhongnan Hospital of Wuhan University Department of Pathology Wuhan Children's HospitalTongji Medical CollegeHuazhong University of Science and Technology

Proteolytic cleavage of tau by asparagine endopeptidase(AEP)creates tau-N368 fragments,which may drive the pathophysiology associated with synaptic dysfunction and memory deterioration in the brain of Alzheimer’s disease ***,the molecular mechanisms of truncated tau-induced cognitive deficits remain *** suggests that signal transduction and activator of transcription-3(STAT3)is associated with modulating synaptic plasticity,cell apoptosis,and cognitive *** luciferase reporter assays,electrophoretic mobility shift assays,western blotting,and immunofluorescence,we found that human tau-N368 accumulation inhibited STAT3 activity by suppressing STAT3 translocation into the *** of STAT3 improved tau-N368-induced synaptic deficits and reduced neuronal loss,thereby improving the cognitive deficits in tau-N368 ***,in tau-N368 mice,activation of STAT3 increased N-methyl-D-aspartic acid receptor levels,decreased Bcl-2 levels,reversed synaptic damage and neuronal loss,and thereby alleviated cognitive deficits caused by *** together,STAT3 plays a critical role in truncated tau-related neuropathological *** indicates a new mechanism behind the effect of tau-N368 on synapses and memory ***3 can be used as a new molecular target to treat tau-N368-induced protein pathology.

关键词： Alzheimer’s disease apoptosis cognitive deficit memory neurodegenerative disease neuron loss N-methyl-D-aspartic acid receptor STAT3 synapse tau-N368