检索结果-南通市图书馆

在线全文

学校读者我要写书评

暂无评论

微生物水泥研究与应用进展

材料工程 2015年第8期43卷 92-103页

作者：钱春香王欣於孝牛东南大学材料科学与工程学院南京211189 东南大学绿色建材技术研究所南京211189

微生物诱导碳酸钙沉积(MICP),即利用微生物代谢活动中矿化行为,诱导形成碳酸钙沉淀,其具有特殊的胶结作用,可作为一种新颖的生物胶凝材料—微生物水泥。本文从MICP矿化机制、胶结机理以及微生物水泥在岩土工程中的应用等方面探讨了相应... 详细信息

微生物诱导碳酸钙沉积(MICP),即利用微生物代谢活动中矿化行为,诱导形成碳酸钙沉淀,其具有特殊的胶结作用,可作为一种新颖的生物胶凝材料—微生物水泥。本文从MICP矿化机制、胶结机理以及微生物水泥在岩土工程中的应用等方面探讨了相应的最新进展,分析了目前存在的问题,并对微生物水泥的进一步研究提出了思路和建议。

关键词： MICP 微生物灌浆砂土

Observation of acoustic hybrid topological phases induced by the p-d orbital interactions

在线全文

学校读者我要写书评

暂无评论

Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 132-139页

作者： xiao Xiang Feng Gao yu-Gui Peng Peng Wu Zong-Lin Li Xue-Feng Zhu School of Physics and Innovation Institute Huazhong University of Science and Technology

In spinless systems,growing attention has recently been attracted to synthetic gauge fields,which redefine the fundamental crystal symmetries by utilizing the projective algebraic ***,synthetic gauge fields have been commonly investigated in single orbital systems,and explorations on hybrid orbitals remain elusive in ***,we report the experimental observation of hybrid topological phases induced by hybrid synthetic gauge flux,which is formed by the interaction between p and d orbitals embedded in acoustic *** breaking the translation symmetries of Lxand/or Ly,we unambiguously demonstrate the first-order M?bius edge states and higher-order corner *** work establishes a platform for seeking exotic topological phases induced by hybrid-orbitals interactions and initializing the framework of hybrid-orbitalsrelated topological *** applications can be anticipated in scenarios such as high-quality sensing and robust wave trapping due to the stepwise energy distribution of the hybrid topological phase.

关键词： topological insulator synthetic gauge field projective symmetry corner states

生物黏附性环孢素纳米脂质载体的制备及其兔泪液消除动力学

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

中国新药与临床杂志 2011年第7期30卷 511-516页

作者：鲍晓肖衍宇牛江秀平其能中国药科大学药剂学教研室江苏南京210009

目的制备具有生物黏附性的环孢素纳米脂质载体(NLC)眼用制剂并考察其在家兔泪液中的消除情况。方法采用熔融-乳化法制备NLC,用生物黏附性材料普流罗尼F127(F127)调节制剂黏度,用Zetasizer纳米粒度仪测定纳米粒粒径,HPLC法考察制剂在家... 详细信息

目的制备具有生物黏附性的环孢素纳米脂质载体(NLC)眼用制剂并考察其在家兔泪液中的消除情况。方法采用熔融-乳化法制备NLC,用生物黏附性材料普流罗尼F127(F127)调节制剂黏度,用Zetasizer纳米粒度仪测定纳米粒粒径,HPLC法考察制剂在家兔泪液中不同时间点药物浓度,以未加入F127的NLC作对照,采用Kinetica4.4计算药动学参数。结果 NLC粒径(35.9±0.2)nm,F127-NLC粒径(41.2±0.2)nm。NLC中F127的含量影响制剂的稳定性,高浓度的F127(9.0%)降低NLC的稳定性,而低浓度的F127(≤6.0%)增加NLC的稳定性。含F127 1.7%、3.3%和6.0%的F127-NLC在兔眼部经6h的泪液消除动力学参数AUC分别为NLC的1.57、1.79和2.42倍,MRT分别为NLC的1.19、1.31和1.90倍。结论加入6.0%的F127制备的NLC可显著提高药物在泪液中的浓度,延长作用时间,减少刺激性。

关键词：环孢菌素生物黏附性纳米结构药物载体普流罗尼F127 眼泪消除动力学

在线全文

学校读者我要写书评

暂无评论

浅论改性纤维-水泥基复合材料试验教学展望

教育现代化 2018年第31期5卷 241-244+248页

作者：高燕於孝牛东北师范大学继续教育学院温州大学建筑工程学院

纤维基水泥复合材料(ECC)以其诸多优点广泛应用于公路桥面板、铁路高架桥、公路隧道等工程领域,但纤维表面光滑,在水泥基材料中易拔出,导致ECC强度、韧性等性能下降。本文综述了国内外近年来工程用水泥基复合材料研究的相关文献,归纳了... 详细信息

纤维基水泥复合材料(ECC)以其诸多优点广泛应用于公路桥面板、铁路高架桥、公路隧道等工程领域,但纤维表面光滑,在水泥基材料中易拔出,导致ECC强度、韧性等性能下降。本文综述了国内外近年来工程用水泥基复合材料研究的相关文献,归纳了对纤维表面进行改性的方法,为试验教学提供理论指导。

关键词：工程用水泥基复合材料纤维强度韧性表面改性

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

养殖牡蛎的选择育种研究与实践

水产学报 2008年第2期32卷 287-295页

作者：肖述喻子牛中国科学院南海海洋研究所中国科学院南海海洋研究所中国科学院海洋生物资源可持续利用重点实验室广东省应用海洋生物学重点实验室广东广州510301

Oyster is one of the commercially important shellfish species in the world, and oyster cultivation has been one of the most prevalent shellfish aquaculture industries. Selective breeding researches and programs for several commercial oyster species are briefly reviewed and the progress made from these programs is summarized in this paper. Particularly, the achievement of genetic improvement for growth, yield and disease resistance in some economically important oysters (the Pacific oyster, American oyster, European oyster and Sydney rock oyster et al.) is outlined accordingly here. So far, some fast growth lines and disease resistant strains have already been created. Two strategies, mass selection or family selection, were employed in these selective researches and programs. Both of them have been proved effective and fruitful. The estimations of heritability for live weight and whole size were in the range of 0.25-0.69 and of 0.2-0.5, respectively. All these efforts and results clearly showed that the regular breeding theories and techniques were applicable to oysters. Hopefully, the developments of regular breeding technology and that of molecular biology technology are expected to create a new era for oyster breeding science and practices in the future.

关键词：牡蛎群体选育家系选育育种

浅论生物修复金属矿区土壤重金属污染研究进展

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

教育现代化 2018年第32期5卷 339-340+345页

作者：高燕於孝牛东北师范大学继续教育学院温州大学建筑工程学院

金属矿区土壤中游离重金属离子对环境造成严重污染。游离重金属离子污染可使生态系统退化、土壤质量下降,同时污染农作物,威胁到人类的健康。目前,修复重金属污染土壤的方法主要有三种:物理、化学和生物方法,其中生物修复方法在近年来... 详细信息

金属矿区土壤中游离重金属离子对环境造成严重污染。游离重金属离子污染可使生态系统退化、土壤质量下降,同时污染农作物,威胁到人类的健康。目前,修复重金属污染土壤的方法主要有三种:物理、化学和生物方法,其中生物修复方法在近年来得到了特别的重视。文章主要介绍了植物修复、微生物矿化修复以及植物-微生物-矿化修复,包括修复原理和优缺点等。矿山固体废物和酸性废水导致矿区土壤中富集大量重金属,结合目前生物修复技术及其应用,对金属矿山重金属污染土壤的整体修复提出设想,构建植物-微生物矿化修复体系。

关键词：金属矿区重金属土壤植物修复微生物矿化修复

应用微生物胶凝材料及脲酶水解机理的教学研讨

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

教育教学论坛 2019年第9期 173-177页

作者：於孝牛高燕温州大学建筑工程学院浙江温州325035 东北师范大学继续教育学院吉林长春130024

微生物矿化是基于微生物诱导矿化形成无机矿物。微生物矿化形成碳酸钙可以作为一类新型胶凝材料,并且可以固结松散的砂土颗粒,在地基加固、扬尘治理等领域具有广泛应用前景。本文主要概述了研究生物矿化方法和微生物碳酸水泥潜在应用砂... 详细信息

微生物矿化是基于微生物诱导矿化形成无机矿物。微生物矿化形成碳酸钙可以作为一类新型胶凝材料,并且可以固结松散的砂土颗粒,在地基加固、扬尘治理等领域具有广泛应用前景。本文主要概述了研究生物矿化方法和微生物碳酸水泥潜在应用砂土加固、水泥基材料裂缝自修复等,详细讨论分析了Bacillus pas-teurii中脲酶水解尿素机理,并指出脲酶水解尿素存在水解和消除竞争。当今研究微生物水泥也存在各个步骤的反应机理、产物晶型的影响机制、复合微生物对矿化晶形如何影响等问题,通过研讨展望指出进一步研究微生物水泥方案。

关键词：微生物矿化胶凝材料砂土颗粒研讨脲酶水解尿素机理

miRNA-21-5p is an important contributor to the promotion of injured peripheral nerve regeneration using hypoxia-pretreated bone marrow-derived neural crest cells

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第1期20卷 277-290页

作者： Meng Cong Jing-Jing Hu Yan yu xiao-Li Li xiao-Ting Sun Li-Ting Wang Xia Wu Ling-Jie Zhu xiao-Jia Yang Qian-Ru He Fei Ding Hai-Yan Shi School of Medicine Nantong UniversityNantongJiangsu ProvinceChina Key Laboratory of Neuroregeneration of Jiangsu and Ministry of Education and Coinnovation Center of Neuroregeneration Nantong UniversityNantongJiangsu ProvinceChina Department of Physiology Jiangsu Health Vocational CollegeNanjingJiangsu ProvinceChina Department of Pathology Affiliated Hospital of Nantong UniversityNantongJiangsu ProvinceChina Jiangsu Clinical Medicine Center of Tissue Engineering and Nerve Injury Repair Affiliated Hospital of Nantong UniversityNantongJiangsu ProvinceChina

Our previous study found that rat bone marrow–derived neural crest cells(acting as Schwann cell progenitors)have the potential to promote long-distance nerve ***-based therapy can enhance peripheral nerve repair and regeneration through paracrine bioactive factors and intercellular ***,the complex contributions of various types of soluble cytokines and extracellular vesicle cargos to the secretome remain *** investigate the role of the secretome and extracellular vesicles in repairing damaged peripheral nerves,we collected conditioned culture medium from hypoxia-pretreated neural crest cells,and found that it significantly promoted the repair of sensory neurons damaged by oxygen-glucose *** mRNA expression of trophic factors was highly expressed in hypoxia-pretreated neural crest *** performed RNA sequencing and bioinformatics analysis and found that miR-21-5p was enriched in hypoxia-pretreated extracellular vesicles of neural crest ***,to further clarify the role of hypoxia-pretreated neural crest cell extracellular vesicles rich in miR-21-5p in axonal growth and regeneration of sensory neurons,we used a microfluidic axonal dissociation model of sensory neurons in vitro,and found that hypoxia-pretreated neural crest cell extracellular vesicles promoted axonal growth and regeneration of sensory neurons,which was greatly dependent on loaded ***,we constructed a miR-21-5p-loaded neural conduit to repair the sciatic nerve defect in rats and found that the motor and sensory functions of injured rat hind limb,as well as muscle tissue morphology of the hind limbs,were obviously *** findings suggest that hypoxia-pretreated neural crest extracellular vesicles are natural nanoparticles rich in ***-21-5p is one of the main contributors to promoting nerve regeneration by the neural crest cell *** helps to explain the mechanism of action of the secretome and e

关键词： axotomy cell-free therapy conditioned medium extracellular vesicles hypoxic preconditioning microRNA oxygen-glucose deprivation peripheral nerve injury Schwann cell precursors

在线全文

学校读者我要写书评

暂无评论

超短超细钢纤维混凝土弯曲性能研究

武汉理工大学学报 2016年第7期38卷 63-68页

作者：孙林柱路鹏飞杨芳赵俊亮於孝牛温州大学建筑工程学院温州325035

为研究钢纤维混凝土(SFRC)的弯曲性能,对不同强度等级(普通混凝土-NC、高强混凝土-HSC)、不同纤维体积掺量和不同纤维长度的钢纤维混凝土梁进行四点弯曲试验。结果表明:纤维长径比越大纤维体积掺量越多,SFRC的极限承载力越大,荷载-挠度... 详细信息

为研究钢纤维混凝土(SFRC)的弯曲性能,对不同强度等级(普通混凝土-NC、高强混凝土-HSC)、不同纤维体积掺量和不同纤维长度的钢纤维混凝土梁进行四点弯曲试验。结果表明:纤维长径比越大纤维体积掺量越多,SFRC的极限承载力越大,荷载-挠度曲线也越饱满;增加纤维掺量可以提高SFRC的抗折初裂强度,且抗折初裂强度随纤维体积掺量的增加线性增加;HSC表现出很好的韧性,但HSC的弯曲韧度比却小于NC。

关键词：钢纤维混凝土钢纤维弯曲韧性长径比