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Prevalence of Helicobacter pylori infection in Chinese military personnel:A cross-sectional,multicenter-based study

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World Journal of Gastroenterology 2025年第3期31卷 42-49页

作者： Han-Chen Min Chun-yan Zhang Fang-yu Wang xiao-Hui yu Shan-Hong Tang Hong-Wu Zhu Ya-Gang Zhao Ji-Luo Liu Jian Wang Jing-Han Guo xiao-Mei Zhang yun-Sheng yang Chinese People’s Liberation Army Medical School Chinese People’s Liberation Army General HospitalBeijing 100853China Department of Gastroenterology and Hepatology The First Medical CenterChinese People’s Liberation Army General HospitalBeijing 100853China Sixth Healthcare Department The Second Medical CenterChinese People’s Liberation Army General HospitalBeijing 100853China Department of Gastroenterology The 940th Hospital of Joint Logistic Support Force of Chinese People’s Liberation ArmyLanzhou 730050Gansu ProvinceChina Department of Gastroenterology General Hospital of Western Theater CommandChengdu 610011Sichuan ProvinceChina Department of Gastroenterology General Hospital of Southern Theater CommandGuangzhou 510010Guangdong ProvinceChina Department of Epidemiology Naval Medical UniversityShanghai 200433China School of Medicine Nankai UniversityTianjin 300071China National Clinical Research Center for Geriatric Diseases Chinese People’s Liberation Army General HospitalBeijing 100853China

BACKGROUND Helicobacter pylori(***)infection is a prevalent disease encountered in military internal medicine and recognized as the main cause of dyspepsia,gastritis,and peptic ulcer,which are common diseases in military *** guidelines in China state all patients with evidence of active infection with *** are offered ***,the prevalence of *** infection and its regional distribution in the military population remain unclear,which hinders effective prevention and treatment *** the prevalence of *** infection in the military population will aid in the development of customized strategies to better manage this infectious *** To investigate the prevalence of *** infection in the Chinese military population in different geographic *** This multicenter,retrospective study included 22421 individuals from five tertiary hospitals located in north,east,southwest,and northwest cities of *** infection was identified using the urea breath test,which had been performed between January 2020 and December *** Of the 22421 military service members,7416(33.1%)were urea breath *** highest prevalence of *** was in the 30-39 years age group for military personnel,with an infection rate of 34.9%.The majority of infected subjects were younger than 40-years-old,accounting for 70.4%of the infected *** individuals serviced in Lanzhou and Chengdu showed a higher infection prevalence than those in Beijing,Nanjing,and Guangzhou,with prevalence rates of 44.3%,37.9%,29.0%,31.1%,and 32.3%,*** *** infection remains a common infectious disease among military personnel in China and has a relatively high prevalence rate in northwest China.

关键词： Helicobacter pylori Prevalence Military personnel Urea breath test Multicenter study

Effects of keto acid supplements on Chinese patients receiving maintenance hemodialysis:a prospective,randomized,controlled,single-center clinical study

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Chinese Medical Journal 2020年第1期133卷 9-16页

作者： Hai-Long Li Hui Li Yi-Fu Cao yue Qi Wei-Qi Wang Shi-Qin Liu Chen-Die yang xiao-yan yu Tao Xu yan Zhu Wei Chen Jian-Ling Tao Xue-Wang Li Department of Clinical Nutrition Peking Union Medical College HospitalPeking Union Medical College&Chinese Academy of Medical SciencesBeijing 100730China Department of Nephrology Shanxi Medical College Affiliated First HospitalTaiyuanShanxi 030001China Department of Nephrology Shijiazhuang Third HospitalShijiazhuangHebei 050011China Department of Nephrology Shanxi Medical College Affiliated Second HospitalTaiyuanShanxi 030001China School of Medicine Stanford UniversityStanfordCA 94305USA Department of Nephrology Peking Union Medical College HospitalPeking Union Medical College&Chinese Academy of Medical SciencesBeijing 100730China Department of Cardiology Ruijin HospitalShanghai Jiao Tong University School of MedicineShanghai 200025China Department of Nephrology Qiqihar Medical College Affiliated Third HospitalQiqiharHeilongjiang 161000China Department of Statistics Institute of Basic Medical SciencesPeking Union Medical College&Chinese Academy of Medical SciencesBeijing 100730China

Background:The effects of keto acid(KA)supplements on Chinese patients receiving maintenance hemodialysis(MHD)are *** study aimed to evaluate the effects of KA supplementation on nutritional status,inflammatory markers,and bioelectric impedance analysis(BIA)parameters in a cohort of Chinese patients with MHD without ***:This was a prospective,randomized,controlled,single-center clinical study conducted in 2011 till ***-nine patients with MHD were randomly assigned to a control(n=14)or a KA(n=15)*** control group maintained a dietary protein intake of 0.9 g/kg/*** KA group received additional KA supplement(0.1 g/kg/day).BIA was used to determine the lean tissue mass,adipose tissue mass,and body cell *** patients,nutritional status,dialysis adequacy,and biochemical parameters were assessed at the ends of the third and sixth months with t test or Wilcoxon rank-sum ***:The daily total energy intake for both groups was about 28 kcal/kg/*** 6 months,the Kt/V(where K is the dialyzer clearance of urea,t is the dialysis time,and V is the volume of the distribution of urea)was 1.33±0.25 in KA group,and 1.34±0.25 in the control *** median triceps skin-fold thickness in KA group was 12.00 and 9.00 mm in the control *** addition,the median hand-grip strength in KA group was 21.10 and 25.65 kg in the control *** were no significant differences between the groups with respect to the anthropometry parameters,dialysis adequacy,serum calcium and phosphorus levels,inflammatory markers,and amino-acid profiles,or in relation to the parameters determined by *** groups achieved dialysis adequacy and maintained nutritional status during the ***:In this cohort of Chinese patients with MHD,the patients in the control group whose dietary protein intake was 0.9 g/kg/day and total energy intake was 28 kcal/kg/day,maintained well nutritional status during study *** KA supplement(0.1 g/kg/

关键词： Chinese Hemodialysis Keto acid Nutrition

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10kV配电网建设优化举措研究

华东电力 2008年第4期36卷 79-82页

作者：颜晓宇贺静上海市电力公司市南供电公司上海200233

现有配电网结构不尽合理和电源点建设相对不足对电网安全、可靠、经济运行产生了负面影响。以漕河泾开发区10 kV配电网为研究对象,对现有10 kV配网存在的问题及其原因进行了全面分析、查找与总结,并在此基础上提出10 kV配电网的规划方... 详细信息

现有配电网结构不尽合理和电源点建设相对不足对电网安全、可靠、经济运行产生了负面影响。以漕河泾开发区10 kV配电网为研究对象,对现有10 kV配网存在的问题及其原因进行了全面分析、查找与总结,并在此基础上提出10 kV配电网的规划方法和项目建设、工询设计、专业技能培养方面的优化措施。在对漕河泾开发区的10 kV配网建设优化的应用中,证实了上述方法和措施在解决10 kV配电网问题时的有效性。

关键词：配网规划项目库评价体系

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TD-ERCS混沌系统的差分分析

物理学报 2007年第1期56卷 78-83页

作者：盛利元闻姜曹莉凌肖燕予中南大学物理科学与技术学院长沙410083 湖南大学数学与计量经济学院长沙410082

基于差分分析基本原理和混沌系统“迭代”与分组密码“轮”的对应关系,提出了迭代差分分布和差分失效指数的概念,用于评估混沌系统抗差分分析的能力.将混沌系统置于“裸”状态,直接分析混沌系统的迭代差分分布,从而测出差分失效指数.研... 详细信息

基于差分分析基本原理和混沌系统“迭代”与分组密码“轮”的对应关系,提出了迭代差分分布和差分失效指数的概念,用于评估混沌系统抗差分分析的能力.将混沌系统置于“裸”状态,直接分析混沌系统的迭代差分分布,从而测出差分失效指数.研究混沌系统的安全性,差分失效指数是一个普适的可测的重要的系统特征指数.对TD-ERCS和Logistic混沌系统的测试结果表明,在90%的参数变化范围内,TD-ERCS的差分失效指数等于2(理论上的最小值),相比之下,Logistic的差分失效指数等于55;推知,TD-ERCS是一种能自动免疫差分分析的混沌系统.

关键词：混沌的安全性差分分析 TD—ERCS Logistic

Mechanism of exogenous nucleic acids and their precursors improving the repair of intestinal epithelium after 7-irradiation in mice

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World Journal of Gastroenterology 2000年第5期6卷 709-717页

作者： Da Xiang Cui~1 Guei Ying Zeng~2 Feng Wang~1 Jun Rong Xu~1 Dong Qing Ren~2 yan Hai Guo~1 Fu Rong Tian~2 xiao Jun yan~1 yu Hou~1 Cheng Zhi Su~1 1 Institute of Genetic Diagnosis of the Fourth Military Medical University,Xi’an 710032,China 2 Department of Irradiation Medicine of the Fourth Military Medical University,Xi’an 710032,China Da Xiang Cui Feng Wang Jun Rong Xu Yan Hai Guo Xiao Jun Yan Yu Hou Cheng Zhi Su Institute of Genetic Diagnosis of the Fourth Military Medical University Xi’an 710032 China Guei Ying Zeng Dong Qing Ren Fu Rong Tian Department of Irradiation Medicine of the Fourth Military Medical University Xi’an 710032 China

AIM To clone expressed genes associated withrepair of irradiation-damaged mice intestinalgland cells treated by small intestinal RNA,andto explore the molecular mechanism ofexogenous nucleic acids improving repair ofintestinal *** The animal mode of test group andcontrol group was established,forty-five micebeing irradiated by γ ray were treated with smallintestinal RNA as test group,forty mice beingirradiated by γ ray were treated withphysiological saline as control group,five micewithout irradiation were used as normal control,their jejunal specimens were collectedrespectively at 6h,12h,24h,4d and 8d *** by using LD-PCR based onsubtractive hybridization,these gene fragmentsdifferentially expressed between test group andcontrol group were obtained,and then werecloned into T vectors as well as *** sequences were ***,if being new sequences,they were submitted to *** Ninety clones were associated withrepair of irradiation-damaged intestinal glandcells treated by intestinal *** clonesfrom test group of 6h,12h,24h,4d and 8dwere respectively 18,22,25,13,*** screening against GeneBank,18 of which werenew sequences,the others were dramaticallysimilar to the known sequences,mainly similarto hsp,Nmi,Dutt1,alkaline phosphatase,homeobox,anti-CEA ScFv antibody,arginine/serine kinase and BMP-4,*** genefragments were new sequences,their acceptnumbers in GeneBank were *** Ninety clones were obtained tobe associated with repair of irradiation-damagedmice intestinal gland cells treated by smallintestinal RNA,which may be related toabnormal expression of genes and matchedproteins of hsp,Nmi,Duttl,Na,K-ATPase,alkalineph-osphatase,glkA,single strandedreplicative centromeric gene as well as 18 newsequences.

关键词： radiation ionizing intestine small/injuries RNA gene expression nucleic acids/therapeutic use polymerase chain reaction repair intestinal epithelium mice

风沙环境下混凝土路面受冲蚀形貌、损伤机理及工况预测

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中国公路学报 2017年第9期30卷 27-33,50页

作者：郝贠洪刘艳晨郭健何晓雁冯玉江江南内蒙古工业大学内蒙古自治区土木工程结构与力学重点实验室内蒙古呼和浩特010051 内蒙古工业大学土木工程学院内蒙古呼和浩特010051

为探究水泥混凝土路面长期遭受风沙环境下的冲蚀磨损损伤机理,根据中国西北地区风沙环境的特征,利用模拟风沙环境侵蚀试验系统研究水泥砂浆在风沙环境下的冲蚀磨损行为。通过冲蚀率来评价水泥砂浆受风沙冲蚀磨损程度,分析了不同冲蚀速... 详细信息

为探究水泥混凝土路面长期遭受风沙环境下的冲蚀磨损损伤机理,根据中国西北地区风沙环境的特征,利用模拟风沙环境侵蚀试验系统研究水泥砂浆在风沙环境下的冲蚀磨损行为。通过冲蚀率来评价水泥砂浆受风沙冲蚀磨损程度,分析了不同冲蚀速度、不同冲蚀角度下水泥砂浆冲蚀率的变化规律;采用扫描电子显微镜(SEM)和激光共聚焦扫描显微镜(LSCM)观测水泥砂浆受冲蚀损伤的表面微观形貌,研究水泥砂浆受冲蚀损伤机理;运用相似理论分析实际工况冲蚀时间和室内模拟冲蚀时间的对应转化关系。研究结果表明:冲蚀角度恒定时,冲蚀率随着冲蚀速度的增大而增大;下沙率恒定、冲蚀角度在30°~90°时,冲蚀率的增长比较明显,近似成正比例变化,90°时冲蚀率达到最大;冲蚀角度是影响冲蚀行为的重要因素,低角度冲蚀时水泥砂浆表现为塑性变形,主要由水平方向的沙粒切削作用导致变形,高角度冲蚀时水泥砂浆表现为脆性破坏,主要由沙粒垂直方向的冲击作用导致材料表面产生冲蚀坑;试验中下沙率越大,由计算结果推算的实际工况中冲蚀磨损时间越长;研究结果可为风沙环境下水泥混凝土路面受磨损损伤研究提供依据。

关键词：道路工程水泥砂浆损伤机理相似性分析冲蚀形貌风沙环境

Multiparameter magnetic resonance imaging-based radiomics model for the prediction of rectal cancer metachronous liver metastasis

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World Journal of Gastrointestinal Oncology 2025年第1期17卷 62-72页

作者： Zhi-Da Long xiao yu Zhi-Xiang Xing Rui Wang Department of Hepatobiliary and Pancreaticosplenic Surgery Jingzhou Hospital Affiliated to Yangtze UniversityJingzhou 434100Hubei ProvinceChina

BACKGROUND The liver,as the main target organ for hematogenous metastasis of colorectal cancer,early and accurate prediction of liver metastasis is crucial for the diagnosis and treatment of ***,this study aims to investigate the application value of a combined machine learning(ML)based model based on the multiparameter magnetic resonance imaging for prediction of rectal metachronous liver metastasis(MLM).AIM To investigate the efficacy of radiomics based on multiparametric magnetic resonance imaging images of preoperative first diagnosed rectal cancer in predicting MLM from rectal *** We retrospectively analyzed 301 patients with rectal cancer confirmed by surgical pathology at Jingzhou Central Hospital from January 2017 to December *** participants were randomly assigned to the training or validation queue in a 7:3 *** first apply generalized linear regression model(GLRM)and random forest model(RFM)algorithm to construct an MLM prediction model in the training queue,and evaluate the discriminative power of the MLM prediction model using area under curve(AUC)and decision curve analysis(DCA).Then,the robustness and generalizability of the MLM prediction model were evaluated based on the internal validation set between the validation queue *** Among the 301 patients included in the study,16.28%were ultimately diagnosed with MLM through pathological *** analysis showed that carcinoembryonic antigen,and magnetic resonance imaging radiomics were independent predictors of ***,the GLRM prediction model was developed with a comprehensive nomogram to achieve satisfactory *** prediction performance of GLRM in the training and validation queue was 0.765[95%confidence interval(CI):0.710-0.820]and 0.767(95%CI:0.712-0.822),*** with GLRM,RFM achieved superior performance with AUC of 0.919(95%CI:0.868-0.970)and 0.901(95%CI:0.850-0.952)in the training and validation queue,respect

关键词： Rectal cancer Metachronous liver metastases Magnetic resonance imaging Radiomics Machine learning

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盐酸青藤碱缓释组合微丸系统的研究

中国药科大学学报 2009年第3期40卷 222-226页

作者：邓艳平肖衍宇平其能顾晓震包全英中国药科大学药剂学教研室南京210009

目的:建立线性叠加组合微丸释药模型,以盐酸青藤碱为模型药,进行模型验证和预测。方法:采用挤出滚圆法制备速释丸,流化床底喷包衣制备肠溶和缓释微丸。根据各种微丸的释药机制选择适宜的释放模型,利用Matlab的曲线拟合工具箱进行拟合... 详细信息

目的:建立线性叠加组合微丸释药模型,以盐酸青藤碱为模型药,进行模型验证和预测。方法:采用挤出滚圆法制备速释丸,流化床底喷包衣制备肠溶和缓释微丸。根据各种微丸的释药机制选择适宜的释放模型,利用Matlab的曲线拟合工具箱进行拟合,根据相关统计参数选择最佳拟合方程,将各种微丸释药方程进行线性叠加,得到组合微丸理论释药方程。根据预期的24h释放要求,利用Matlab解析线性不等式或线性方程组,预测各种微丸所需用量并实际组合,将释放试验结果与预测值进行对比验证。结果:对组合系统释药行为的数学解析结果显示,预测值(组合微丸理论释药方程)与实测值较接近,说明组合系统的释药行为是可控的,能较好地预测组合各种微丸所需的用量以满足不同释放行为的需要。结论:有预见性地组合不同的微丸或为不同组合比例提供了一种设计缓释系统的新方法。

关键词：盐酸青藤碱速释丸肠溶微丸缓释微丸组合释药 Matlab

GS-ASTFA方法及其在滚动轴承寿命预测中的应用

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振动与冲击 2017年第11期36卷 14-19页

作者：欧龙辉彭晓燕杨宇程军圣湖南大学汽车车身先进设计制造国家重点实验室长沙410082

自适应最稀疏时频分析(Adaptive and Sparsest Time-Frequency Analysis,ASTFA)方法是一种新的信号分解方法,该方法将信号分解问题转化为优化问题,以得到信号的最稀疏解。优化过程采用高斯-牛顿迭代算法,但高斯-牛顿迭代算法对初值依赖... 详细信息

自适应最稀疏时频分析(Adaptive and Sparsest Time-Frequency Analysis,ASTFA)方法是一种新的信号分解方法,该方法将信号分解问题转化为优化问题,以得到信号的最稀疏解。优化过程采用高斯-牛顿迭代算法,但高斯-牛顿迭代算法对初值依赖性高,采用黄金分割法(Golden Section,GS)对ASTFA方法进行初值搜索,提出了基于黄金分割搜索初值的ASTFA方法(GS-ASTFA),仿真信号的分析结果验证了改进方法的有效性。继而采用该方法提取了滚动轴承故障特征值,并成功地进行了故障特征值趋势分析和寿命预测。

关键词：自适应最稀疏时频分析黄金分割法趋势分析寿命预测