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Expression and location of α-fetoprotein during rat colon development

World Journal of Gastroenterology 2009年第14期15卷 1738-1743页

作者： xiao-yan liu dan dong peng sun jun du luo gu ying-bin ge Department of Physiology Nanjing Medical University Nanjing 210029 Jiangsu Province China

AIM： To investigate the expression of α-fetoprotein （AFP）, a cancer-associated fetal glycoprotein, and its involvement during rat colon development. METHODS： Colons from Sprague-Dawley rat fetuses, young and adult （8 wk old） animals were used in this study. Expression levels of AFP in colons of different development stage were detected by reversetranscriptase PCR （RT-PCR） and Western blotting. To identify the cell location of AFP in the developing rat colons, double-immunofluorescent staining was performed using antibodies to specific cell markers and AFP, respectively. RESULTS： The highest levels of AFP mRNA were detected in colons of rats at embryonic day 18.5 （e18.5）. Compared to e18.5 d, the AFP expression was significantly decreased during rat development （85% for e20.5, P 〈 0.05, 58% for postnatal day 0.5 （P〈0.5）, P 〈 0.05, 37% for P7, P 〈 0.05, 24% for P14, P 〈 0.05, and 11% for P21, P 〈 0.05） and undetected in adult rats. Only the 72-kDa isoform of AFP was detected by Western blotting, the expression pattern was similar to AFP mRNA and conformed to the results of mRNA expression. The AFP positive staining was identical to different distribution patterns in fetuses, young and adult animals and positive staining for both AFP and vimentin was overlapped in mesenchymal cells at each stage tested. CONCLUSION： This study has for the first time demonstrated that AFP is localized in the mesenchyme of rat colon from the embryo to the weaning stage by immunofluorescence and presents 72-kDa isoform in the developing rat colons by Western blotting. The dynamic expression of AFP in the various developmental stages of the colon indicates that AFP might be involved in many aspects of colon development.

关键词： Alpha-fetoprotein Development Mesenchyme Colon Rat

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α-fetoprotein involvement during glucocorticoid-induced precocious maturation in rat colon

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World Journal of Gastroenterology 2011年第24期17卷 2933-2940页

作者： Min Chen peng sun xiao-yan liu dan dong jun du luo gu ying-bin ge Lian Yun Gang Higher Vocational Technical College of Traditional Chinese Medicine Lianyungang 222006 Jiangsu Province China Department of Physiology Nanjing Medical University Nanjing 210029 Jiangsu Province China The Laboratory Center for Basic Medical Sciences Nanjing Medical University Nanjing 210029 Jiangsu Province China

AIM： TO investigate the role of a-fetoprotein （AFP）, a cancer-associated fetal glycoprotein, in glucocorticoidinduced precocious maturation in rat colon. METHODS： Colons from suckling Sprague-Dawley rats were used in this study. Corticosterone acetate at a dose of 100 μg/g body weight was given to normal pups on days 7, 9 and 11 after birth to induce hypercorticoidism. Control animals were injected with identical volumes of normal saline. Some rats receiving corticosterone 7 d after birth were also treated with mifepristone （RU38486）, a glucocorticoid cytoplasm receptor antagonist to investigate the effects of glucocorticoids （GCs）. The morphological changes of the crypt depth and villous height of the villous zone in colon were observed as indicesof colon maturation. Expression levels of AFP in colons were detected by reverse transcriptase polymerase chain reaction and Western blotting. To identify the cellular lo- calization of AFP in developing rat colons, double-immu- nofluorescent staining was performed using antibodies to specific mesenchymal cell marker and AFP. RESULTS： Corticosterone increased the crypt depth and villous height in the colon of 8- and 10-d-old rats with hypercorticoidism compared with that in the control ani- mals （120% in 8-d-old rats and 118% in 10-d-old rats in villous height, P = 0.021; 145% in 8-d-old rats and 124% in 10-d-old rats in crypt depth, P = 0.017）. These increases were accompanied by an increase of AFP ex- pression in both mRNA and protein （2.5-folds in 8-d- old and 2.5-folds in 10-d-old rats higher than in control animals, P = 0.035; 1.8-folds in 8-d-old and 1.3-folds in 10-d-old rats higher than in control animals, P = 0.023）. Increased crypt depth and villous height and increased expression of AFP in the colon of rats with hypercorti- coidism were blocked by mifepristone. Both had positive staining for AFP or vimentin, and overlapped in mesen- chymal cells at each tested colon. CONCLUSION： GCs promote the development of ra

关键词： Glucocorticoids a-fetoprotein Precociousmaturation Colon Rat

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CEPC Technical Design Report

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Radiation Detection Technology and Methods 2024年第1期8卷 I0003-I0016,1-1091页

作者： Waleed Abdallah Tiago Carlos Adorno de Freitas Konstantin Afanaciev Shakeel Ahmad Ijaz Ahmed xiaocong Ai Abid Aleem Wolfgang Altmannshofer Fabio Alves Weiming An Rui An daniele Paolo Anderle Stefan Antusch Yasuo Arai Andrej Arbuzov Abdesslam Arhrib Mustafa Ashry Sha Bai Yu Bai yang Bai Vipul Bairathi Csaba Balazs Philip Bambade Yong Ban Tripamo Bandyopadhyay Shou-Shan Bao Desmond P.Barber Ayse Bat Varvara Batozskaya Subash Chandra Behera Alexander Belyaev Michele Bertucci xiao-jun Bi Yuanjie Bi Tianjian Bian Fabrizio Bianchi Thomas Biekotter Michela Biglietti Shalva Bilanishvili Deng binglin Denis Bodrov Anton Bogomyagkov Serge Bondarenko Stewart Boogert Maarten Boonekamp Marcello Borri Angelo Bosotti Vincent Boudry Mohammed Boukidi Igor Boyko Ivanka Bozovic Giuseppe Bozzi Jean-Claude Brient Anastasiia Budzinskaya Masroor Bukhari Vladimir Bytev Giacomo Cacciapaglia Hua Cai Wenyong Cai Wujun Cai Yijian Cai Yizhou Cai Yuchen Cai Haiying Cai Huacheng Cai Lorenzo Calibbi junsong Cang guofu Cao Jianshe Cao Antoine Chance Xuejun Chang Yue Chang Zhe Chang Xinyuan Chang Wei Chao Auttakit Chatrabhuti Yimin Che Yuzhi Che bin Chen danping Chen Fuqing Chen Fusan Chen Gang Chen guoming Chen Hua-Xing Chen Huirun Chen Jinhui Chen Ji-Yuan Chen Kai Chen Mali Chen Mingjun Chen Mingshui Chen Ning Chen Shanhong Chen Shanzhen Chen Shao-Long Chen Shaomin Chen Shiqiang Chen Tianlu Chen Wei Chen Xiang Chen xiaoyu Chen Xin Chen Xun Chen Xurong Chen Ye Chen ying Chen Yukai Chen Zelin Chen Zilin Chen Gang Chen Boping Chen Chunhui Chen Hok Chuen Cheng Huajie Cheng Shan Cheng Tongguang Cheng Yunlong Chi Pietro Chimenti Wen Han Chiu guk Cho Ming-Chung Chu xiaotong Chu Ziliang Chu guglielmo Coloretti Andreas Crivellin Hanhua Cui xiaohao Cui Zhaoyuan Cui Brunella D'Anzi Ling-Yun Dai Xinchen Dai Xuwen Dai Antonio De Maria Nicola De Filippis Christophe De La Taille Francesca De Mori Chiara De Sio Elisa Del Core Shuangxue Deng Wei-Tian Deng Zhi Deng Ziyan Deng Bhupal Dev Tang Dewen Biagio Di Micco Ran Ding Siqin Dingl Yadong Ding Haiyi dong Jianin AGH University of Science and Technology Faculty of Physics and Applied Computer ScienceKrakow Anhui University HefeiAnhui Applied Physics Department Federal Urdu University of ArtsScience and TechnologyIslamabad Banaras Hindu University Institute of ScienceVaranasi Bandirma Onyedi Eylul University Bandirma Beihang University Beijing Beijing Computational Science Research Center Beijing Beijing Conveyi LTD Beijing Beijing Glass Research Institute Co. LtdBeijing Beijing Institute of Technology Beijing Beijing Normal University Beijing Brown University ProvidenceRI Budker Institute of Nuclear Physics Novosibirsk Cadi Ayyad University Laboratory of Fundamental and Applied PhysicsPolydisciplinary FacultyMarrakech Cairo University Giza Center for Theory and Computation National Tsing Hua UniversityHsinchu Central China Normal University WuhanHubei Central South University ChangshaHunan Centro de Fisica Teorica de Particulas Universidade Tecnica de LisboaLisboa Chengdu KaitengSifang Digital Radio&TV Equipment Co. LtdChengduSichuan China academy of engineering physics MianyangSichuan China building materials academy Beijing China Center of Advanced Science and Technology Beijing China Institute of Atomic Energy Beijing China Jiliang University HangzhouZhejiang China Nuclear Instrument CO. LTDBeijing China University of geosciences Beijing China University of geosciences WuhanHubei China University of Mining and Technology XuzhouJiangsu China West Normal University NanchongSichuan Chongqing University Department of PhysicsChongqing Chulalongkorn University Bangkok City University of Hong Kong Department of PhysicsHong Kong Cockcroft Institute Daresbury Cornell University IthacaNY CPPM(AMU/IPhU&CNRS/INP) Marseille Dalian Minzu University DalianLiaoning Dalian University of Technology Department of PhysicsDalian Deutsches Elektronen-Synchrotron DESY Hamburg Dzhelepov Laboratory of Nuclear Problems of Joint Institute for Nuclear Research(DLNP JINR) Dubna East China University Of Science And Technol

The Circular Electron Positron Collider(CEPC)is a large scientific project initiated and hosted by China,fostered through extensive collaboration with international *** complex comprises four accelerators:a 30 geV Linac,a 1.1 geV Damping Ring,a Booster capable of achieving energies up to 180 geV,and a Collider operating at varying energy modes(Z,W,H,and tt).The Linac and Damping Ring are situated on the surface,while the subterranean Booster and Collider are housed in a 100 km circumference underground tunnel,strategically accommodating future expansion with provisions for a potential Super Proton Proton Collider(SPPC).The CEPC primarily serves as a Higgs *** its baseline design with synchrotron radiation(SR)power of 30 MW per beam,it can achieve a luminosity of 5×10^(34)cm^(-2)s^(-1)per interaction point(IP),resulting in an integrated luminosity of 13 ab^(-1)for two IPs over a decade,producing 2.6 million Higgs *** the SR power to 50 MW per beam expands the CEPC's capability to generate 4.3 million Higgs bosons,facilitating precise measurements of Higgs coupling at sub-percent levels,exceeding the precision expected from the HL-LHC by an order of *** Technical Design Report(TDR)follows the Preliminary Conceptual Design Report(Pre-CDR,2015)and the Conceptual Design Report(CDR,2018),comprehensively detailing the machine's layout,performance metrics,physical design and analysis,technical systems design,R&D and prototyping efforts,and associated civil engineering ***,it includes a cost estimate and a preliminary construction timeline,establishing a framework for forthcoming engineering design phase and site selection *** is anticipated to begin around 2027-2028,pending government approval,with an estimated duration of 8 *** commencement of experiments and data collection could potentially be initiated in the mid-2030s.

关键词： initiated exceeding precise

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基于白光中子源的^(197)Au中子辐射俘获截面测量及共振参数分析

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物理学报 2024年第7期73卷 104-113页

作者：罗淏天张奇玮栾广源王晓宇邹翀任杰阮锡超贺国珠鲍杰孙琪黄翰雄王朝辉吴鸿毅顾旻皓余滔解立坤陈永浩安琪白怀勇鲍煜曹平陈昊磊陈琪萍陈裕凯陈朕崔增琪樊瑞睿封常青高可庆韩长材韩子杰何泳成洪杨黄蔚玲黄锡汝季筱璐吉旭阳蒋伟江浩雨姜智杰敬罕涛康玲康明涛李波李超李嘉雯李论李强李晓李样刘荣刘树彬刘星言穆奇丽宁常军齐斌斌任智洲宋英鹏宋朝晖孙虹孙康孙晓阳孙志嘉谭志新唐洪庆唐靖宇唐新懿田斌斌王丽娇王鹏程王琦王涛峰文杰温中伟吴青彪吴晓光吴煊羊奕伟易晗于莉于永积张国辉张林浩张显鹏张玉亮张志永赵豫斌周路平周祖英朱丹阳朱科军朱鹏朱兴华中国原子能科学研究院核数据重点实验室北京102413 中国科学院高能物理研究所北京100049 散裂中子源科学中心东莞523803 核探测与核电子学国家重点实验室北京100049 中国科学技术大学近代物理系核探测与核电子学国家重点实验室合肥230026 北京大学物理学院核物理与核技术国家重点实验室北京100871 中国工程物理研究院核物理与化学研究所绵阳621900 西北核技术研究院西安710024 中国科学院大学北京100049 中国科学技术大学工程与应用物理系合肥230026 北京航空航天大学物理学院北京100083 华能山东石岛湾核电有限公司荣成264312

中子辐射俘获反应在反应堆运行、核装置设计及核天体物理研究中起重要的作用.4πBaF_(2)探测装置有着高时间分辨能力、低中子灵敏度、高探测效率等优点,适合开展中子辐射俘获反应截面数据的测量.中国原子能科学研究院核数据重点实验室... 详细信息

中子辐射俘获反应在反应堆运行、核装置设计及核天体物理研究中起重要的作用.4πBaF_(2)探测装置有着高时间分辨能力、低中子灵敏度、高探测效率等优点,适合开展中子辐射俘获反应截面数据的测量.中国原子能科学研究院核数据重点实验室建立了伽马全吸收装置(Gamma total absorption facility,GTAF),该装置用28块六棱BaF_(2)晶体和12块五棱BaF_(2)晶体构成了外径25 cm,内径10 cm的球壳,覆盖了95.2%的立体角.利用GTAF在中国散裂中子源Back-n束线上,测量了197Au(n,γ)的反应截面数据.测量数据通过能量筛选、PSD方法、晶体多重性筛选进行了初步本底扣除,随后结合对^(nat)C及空样品的测量数据对本底进行了分析及扣除,获得了197Au俘获反应的产额,利用SAMMY程序拟合得到了^(197)Au在1—100 e V的共振能量、中子共振宽度和伽马共振宽度参数.实验测量结果与ENDF/B-VIII.0数据库符合良好,其共振参数存在一定差异,分析原因可能与GTAF能量分辨率、Back-n的中子能谱测量精度、以及实验本底扣除方法相关,这也是下一步工作的重点.

关键词：中子辐射俘获截面共振参数白光中子源伽马全吸收装置

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Prevalence and clinical characteristics of autoimmune liver disease in hospitalized patients with cirrhosis and acute decompensation in China

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World Journal of Gastroenterology 2022年第31期28卷 4417-4430页

作者： Zi-Xuan Shen dan-dan Wu Jie Xia Xian-Bo Wang Xin Zheng yan Huang Bei-Ling Li Zhong-Ji Meng yan-Hang Gao Zhi-Ping Qian Feng liu xiao-Bo Lu Jia Shang Hua-dong yan Yu-Bao Zheng Wen-Yi gu yan Zhang Jian-Yi Wei Wen-Ting Tan Yi-Xin Hou Qun Zhang yan Xiong Cong-Cong Zou jun Chen Ze-bing Huang Xiu-Hua Jiang Sen luo Yuan-Yuan Chen Na Gao Chun-yan liu Wei Yuan Xue Mei Jing Li Tao Li Xin-Yi Zhou guo-Hong Deng Jin-jun Chen Xiong Ma Hai Li Department of Gastroenterology Renji HospitalSchool of MedicineShanghai Jiao Tong UniversityShanghai 200127China Shanghai Institute of Digestive Disease Key Laboratory of Gastroenterology and HepatologyChinese Ministry of HealthShanghai Jiao Tong UniversityShanghai 200001China Department of Infectious Diseases Southwest HospitalThe Third Military Medical University(Army Medical University)Chongqing 400038China Center of Integrative Medicine Beijing Ditan HospitalCapital Medical UniversityBeijing 100102China Department of Infectious Diseases Institute of Infection and ImmunologyUnion HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430022Hubei ProvinceChina Department of Infectious Diseases Hunan Key Laboratory of Viral HepatitisXiangya HospitalCentral South UniversityChangsha 410008Hunan ProvinceChina Hepatology Unit Department of Infectious DiseasesNanfang HospitalSouthern Medical UniversityGuangzhou 510515Guangdong ProvinceChina Department of Infectious Disease Taihe HospitalHubei University of MedicineShiyan 430418Hubei ProvinceChina Department of Hepatology The First Hospital of Jilin UniversityChangchun 130031Jilin ProvinceChina Department of Liver Intensive Care Unit Shanghai Public Health Clinical CentreFudan UniversityShanghai 201508China Tianjin Institute of Hepatology Nankai University Second People’s HospitalTianjin 300102China Department of Infectious Diseases and Hepatology The Second Hospital of Shandong UniversityJinan 250033Shandong ProvinceChina Infectious Disease Center The First Affiliated Hospital of Xinjiang Medical UniversityUrumqi 830054XinjiangChina Department of Infectious Diseases Henan Provincial People’s HospitalZhengzhou 450003Henan ProvinceChina Department of Infectious Diseases Hwamei HospitalThe Second Hospital of NingboUniversity of Chinese Academy of SciencesNingbo 315153Zhejiang ProvinceChina Department of Infectious Diseases The Third Affiliated Hospital of Sun Yat-sen UniversityGuangzhou 5

BACKGROUND Autoimmune liver disease(AILD)has been considered a relatively uncommon disease in China,epidemiological data for AILD in patients with cirrhosis and acute decompensation(AD)is *** To investigate the prevalence,outcome and risk factors for AILD in cirrhotic patients complicated with AD in *** We collected data from patients with cirrhosis and AD from two prospective,multicenter cohorts in hepatitis B virus endemic *** were regularly followed up at the end of 28-d,90-d and 365-d,or until death or liver transplantation(LT).The primary outcome in this study was 90-d LTfree ***-on-chronic liver failure(ACLF)was assessed on admission and during 28-d hospitalization,according to the diagnostic criteria of the European Association for the Study of the Liver(EASL).Risk factors for death were analyzed with logistic regression *** In patients with cirrhosis and AD,the overall prevalence of AILD was 9.3%(242/2597).Prevalence of ACLF was significantly lower in AILD cases(14%)than those with all etiology groups with cirrhosis and AD(22.8%)(Pbin(TB),hepatic encephalopathy(HE)and blood urea nitrogen(BUN)were independent risk factors for 90-d LT-free mortality in multivariate *** development of ACLF during hospitalization only independently correlated to TB and international normalized *** AILD was not rare in hospitalized patients with cirrhosis and AD in China,among which PBC was the m

关键词： Prevalence Autoimmune liver disease Cirrhosis and acute decompensation Mortality Acuteon-chronic liver failure

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Expert consensus on clinical standardized application of high-flow nasal cannula oxygen therapy in adults

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Chinese Medical Journal 2020年第11期133卷 1322-1324页

作者： Jian-Qiao Xu Long-Xiang Su peng yan Xing-Shuo Hu Ruo-Xuan Wen Kun xiao Hong-jun gu Jin-gen Xia bing sun Qing-Tao Zhou Yu-Chao dong Jia-Lin liu Pin-Hua Pan Hong luo Qi Li Li-Qiang Song Si-Cheng Xu yan-Ming Li Dao-Xin Wang dan Li Qing-Yuan Zhan Li-Xin Xie 无 Departm ent of Pulmonary&Critical Care Medicine Chinese People Liberation Army(PLA)General HospitalBeijing 100853China Department of Critical Care Medicine Peking Union Medical College HospitalBeijing 100005China Department of Pulmonary&Critical Care Medicine China and Japan Friendship HospitalBeijing 100029China Department of Pulmonary&Critical Care Medicine Beijing Chaoyang Hospital affiliated to Capital Medical UniversityBeijing 100020China Department of Pulmonary&Critical Care Medicine Peking University Third HospitalBeijing 100191China Department of Respiratory Medicine Changhai HospitalShanghai 200433China Department of Respiratory Medicine Ruijin Hospital Affiliated to the Shanghai Jiao Tong University Medical SchoolShanghai 200025China Department of Respiratory Medicine XiangYa HospitalCentral South UniversityChangshaHunan 410008China Department of Pulmonary&Critical Care Medicine XiangYa Second Hospital of Central South UniversityChangshaHunan 410011China Department of Pulmonary&Critical Care Medicine Xinqiao Hospital of the Third Military Medical UniversityChongqing 400037China Department of Pulmonary&Critical Care Medicine Xijing Hospital of Fourth Military Medical UniversityXi'anShaanxi 710032China Department of Respiratory Medicine The First Affiliated Hospital of Xinjiang Medical UniversityUrumqiXinjiang 830000China Department of Pulmonary&Critical Care Medicine Beijing HospitalBeijing 100730China Department of Respiratory Medicine The Second Affiliated Hospital of Chongqing Medical UniversityChongqing 400010China Department of Respiratory Medicine The First Bethune Hospital of Jilin UniversityChangchunJilin 130021China Pulmonary&Critical Care Medicine Group of Chinese Thoracic Society/Pulmonary&Critical Care Medicine Committee of Chinese Association of Chest Physician

High-flow nasal cannula oxygen therapy(HFNC)is a novel respiratory support technology and has been extensively applied in clinics in recent *** therapeutic equipment mainly includes an air-oxygen blender,an active humidifier,a high-flow nasal cannula,and a connecting inspiratory *** provides patients a humidified high-flow gas(8-80 L/min)with relatively stable oxygen concentration(21-100%),temperature(31-37℃)and performs oxygen therapy via a nasal cannula,which is very comfortable.

关键词： flow connecting high

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Panda X-III： Searching for neutrinoless double beta decay with high pressure ^(136)Xe gas time projection chambers

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Science China(Physics,Mechanics & Astronomy) 2017年第6期60卷 8-47页

作者： Xun Chen Chang Bo Fu Javier Galan Karl Giboni Franco Giuliani Ling Hui gu Ke Han Xiang dong Ji Heng Lin Jiang Lai liu Kai Xiang Ni Hiroki Kusano Xiang Xiang Ren Shao Bo Wang Yong yang dan Zhang Tao Zhang Li Zhao Xiang Ming sun Shou yang Hu Si Yu Jian Xing Long Li xiao Mei Li Hao Liang Huan Qiao Zhang Ming Rui Zhao Jing Zhou Ya jun Mao Hao Qiao Si guang Wang ying Yuan Meng Wang Amir N.Khan Neill Raper Jian Tang Wei Wang Jia Ning dong Chang Qing Feng Cheng Li Jian Bei liu Shu bin liu xiao Lian Wang dan yang Zhu Juan F.Castel Susana Cebri'an Theopisti Dafni Javier G.Garza Igor G.Irastorza Francisco J.Iguaz Gloria Luz ′on Hector Mirallas Stephan Aune Eric Berthoumieux yann Bedfer Denis Calvet Nicole d'Hose Alain Delbart Maria Diakaki Esther Ferrer-Ribas Andrea Ferrero Fabienne Kunne Damien Neyret Thomas Papaevangelou Franck Sabatie Maxence Vanderbroucke AnDi Tan Wick Haxton Yuan Mei Chinorat Kobdaj Yu-peng yan NPAC and Department of Physics and Astronomy Shanghai Jiao Tong University Shanghai Laboratory for Particle Physics and Cosmology Shanghai 200240 China College of Physical Science and Technology Central China Normal University Wuhan 430079 China China Institute of Atomic Energy Beijing 102413 China School of Physics Peking University Beijing 100871 China School of Physics and Key Laboratory of Particle Physics and Particle Irradiation (MOE) Shandong University Jinan 250100 China School of Physics and Engineering Sun Yat-Sen University Guangzhou 510275 China Department of Modern Physics University of Science and Technology of China Hefei 230026 China State Key Laboratory of Particle Detection and Electronics University of Science and Technology of China Hefei 230026 China University ofZaragoza C/P Cerbuna 12 50009 Zaragoza Spain IRFU CEA Universite Paris-Saclay F-91191 Gif-sur-Yvette France Department of Physics University of Maryland College Park MD 20742 USA Nuclear Science Division Lawrence Berkeley National Laboratory Berkeley CA 94720 USA Center for Excellence in High Energy Physics and Astrophysics Suranaree University of Technology Nakhon Ratchasima 30000 Thailand

Searching for the neutrinoless double beta decay(NLDBD)is now regarded as the topmost promising technique to explore the nature of neutrinos after the discovery of neutrino masses in oscillation *** X-III(particle and astrophysical xenon experiment III)will search for the NLDBD of136Xe at the China Jin Ping Underground Laboratory(CJPL).In the first phase of the experiment,a high pressure gas Time Projection Chamber(TPC)will contain 200 kg,90%136Xe enriched gas operated at10 *** pitch micro-pattern gas detector(Microbulk Micromegas)will be used at both ends of the TPC for the charge readout with a cathode in the *** signals can be used to reconstruct the electron tracks of the NLDBD events and provide good energy and spatial *** detector will be immersed in a large water tank to ensure～5 m of water shielding in all *** second phase,a ton-scale experiment,will consist of five TPCs in the same water tank,with improved energy resolution and better control over backgrounds.

关键词： neutrinoless double beta decay lepton number violation underground experiment TPC Micromegas

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Timing analysis of the black hole candidate EXO 1846–031 with Insight-HXMT monitoring

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Research in Astronomy and Astrophysics 2021年第3期21卷 193-204页

作者： He-Xin liu Yue Huang guang-Cheng xiao Qing-Cui Bu Jin-Lu Qu Shu Zhang Shuang-Nan Zhang Shu-Mei Jia Fang-jun Lu Xiang Ma Lian Tao Wei Zhang Li Chen Li-Ming Song Ti-Pei Li Yu-peng Xu Xue-Lei Cao Yong Chen Cong-Zhan liu Ce Cai Zhi Chang Gang Chen Tian-Xiang Chen Yi-Bao Chen Yu-peng Chen Wei Cui Wei-Wei Cui Jing-Kang Deng Yong-Wei dong Yuan-Yuan du Min-Xue Fu guan-Hua Gao He Gao Min Gao Ming-Yu ge Yu-dong gu Ju guan Cheng-Cheng guo Da-Wei Han Jia Huo Lu-Hua Jiang Wei-Chun Jiang Jing Jin Yong-Jie Jin Ling-Da Kong bing Li Cheng-Kui Li Gang Li Mao-Shun Li Wei Li Xian Li xiao-Bo Li Xu-Fang Li yang-guo Li Zheng-Wei Li xiao-Hua Liang Jing-Yuan Liao Bai-Sheng liu guo-Qing liu Hong-Wei liu xiao-Jing liu Yi-Nong liu Bo Lu Xue-Feng Lu Qi luo Tao luo bin Meng Yi Nang Jian-Yin Nie ge Ou Na Sai Ren-Cheng Shang Xin-ying Song Liang sun ying Tan You-Li Tuo Chen Wang guo-Feng Wang Juan Wang Ling-jun Wang Weng-Shuai Wang Yu-Sa Wang Xiang-yang Wen Bai-yang Wu Bo-bing Wu Mei Wu Shuo xiao Shao-Lin Xiong He Xu Jia-Wei yang Sheng yang yan-Ji yang Yi-jung yang Qi-bin Yi Qian-Qing Yin Yuan You Ai-Mei Zhang Cheng-Mo Zhang Fan Zhang Hong-Mei Zhang Juan Zhang Tong Zhang Wan-Chang Zhang Wen-Zhao Zhang Yi Zhang Yi-Fei Zhang Yong-Jie Zhang Yuan-Hang Zhang Yue Zhang Zhao Zhang Zhi Zhang Zi-Liang Zhang Hai-Sheng Zhao xiao-Fan Zhao Shi-Jie Zheng Yao-guang Zheng Deng-Ke Zhou Jian-Feng Zhou Yu-Xuan Zhu Ren-Lin Zhuang Yue Zhu Key Laboratory of Particle Astrophysics Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China University of Chinese Academy of Sciences Chinese Academy of SciencesBeijing 100049China Institut fur Astronomie und Astrophysik Kepler Center for Astro and Particle PhysicsEberhard Karls Universität72076 TubingenGermany Department of Astronomy Beijing Normal UniversityBeijing 100088China Department of Astronomy Tsinghua UniversityBeijing 100084China Department of Physics Tsinghua UniversityBeijing 100084China Department of Engineering Physics Tsinghua UniversityBeijing 100084China Key Laboratory of Space Astronomy and Technology National Astronomical ObservatoriesChinese Academy of SciencesBeijing 100101China College of Physics Sciences&Technology Hebei UniversityBaoding 071002Hebei ProvinceChina

We present the observational results from a detailed timing analysis of the black hole candidate EXO 1846-031 during its outburst in 2019 with the observations of Insight-HXMT,NICER and *** outburst can be classified roughly into four different ***-C quasi-periodic oscillations(QPOs)observed by NICER(about 0.1-6 Hz)and Insight-HXMT(about 0.7-8 Hz)are also reported in this ***,we study various physical quantities related to QPO *** QPO rms-frequency relationship in the energy band 1-10 keV indicates that there is a turning pointing in frequency around2 Hz,which is similar to that of GRS 1915+105.A possible hypothesis for the relationship above may be related to the inclination of the source,which may require a high inclination to explain *** relationships between QPO frequency and QPO rms,hardness,total fractional rms and count rate have also been found in other transient sources,which can indicate that the origin of type-C QPOs is non-thermal.

关键词： X-ray binaries black hole candidate QPO EXO 1846–031

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The first data release(DR1) of the LAMOST regular survey

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Research in Astronomy and Astrophysics 2015年第8期15卷 1095-1124页

作者： A-Li luo Yong-Heng Zhao Gang Zhao Li-Cai Deng xiao-Wei liu Yi-peng Jing Gang Wang Hao-Tong Zhang Jian-Rong Shi Xiang-Qun Cui Yao-Quan Chu guo-Ping Li Zhong-Rui Bai Yue Wu yan Cai Shu-Yun Cao Zi-Huang Cao Jeffrey L.Carlin Hai-Yuan Chen Jian-jun Chen Kun-Xin Chen Li Chen Xue-Lei Chen xiao-yan Chen ying Chen Norbert Christlieb Jia-Ru Chu Chen-Zhou Cui Yi-Qiao dong bing du dong-Wei Fan Lei Feng Jian-Ning Fu peng Gao Xue-Fei Gong Bo-Zhong gu yan-Xin guo Zhan-Wen Han Bo-Liang He Jin-Liang Hou Yong-Hui Hou Wen Hou Hong-Zhuan Hu Ning-Sheng Hu Zhong-Wen Hu Zhi-ying Huo Lei Jia Fang-Hua Jiang Xiang Jiang Zhi-Bo Jiang ge Jin xiao Kong Xu Kong Ya-Juan Lei Ai-Hua Li Chang-Hua Li guang-Wei Li Hai-Ning Li Jian Li Qi Li Shuang Li Sha-Sha Li Xin-Nan Li yan Li Yin-Bi Li Ye-Ping Li Yuan Liang Chien-Cheng Lin Chao liu gen-Rong liu guan-Qun liu Zhi-Gang liu Wen-Zhi Lu Yu luo Yin-dun Mao Heidi Newberg Ji-jun Ni Zhao-Xiang Qi Yong-jun Qi Shi-Yin Shen Huo-Ming Shi Jing Song Yi-Han Song Ding-Qiang Su Hong-jun Su Zheng-Hong Tang Qing-Sheng Tao Yuan Tian dan Wang Da-Qi Wang Feng-Fei Wang guo-Min Wang Hai Wang Hong-Chi Wang Jian Wang Jia-Ning Wang Jian-Ling Wang Jian-Ping Wang jun-Xian Wang Lei Wang Meng-Xin Wang Shou-guan Wang Shu-Qing Wang Xia Wang Ya-Nan Wang You Wang Yue-Fei Wang You-Fen Wang peng Wei Ming-Zhi Wei Hong Wu Ke-Fei Wu Xue-bing Wu Yu-Zhong Wu xiao-Zheng Xing Ling-Zhe Xu Xin-Qi Xu yan Xu Tai-Sheng yan De-Hua yang Hai-Feng yang Hui-Qin yang Ming yang Zheng-Qiu Yao Yong Yu Hui Yuan Hai-Bo Yuan Hai-Long Yuan Wei-Min Yuan Chao Zhai En-peng Zhang Hua-Wei Zhang Jian-Nan Zhang Li-Pin Zhang Wei Zhang Yong Zhang yan-Xia Zhang Zheng-Chao Zhang Ming Zhao Fang Zhou Xu Zhou Jie Zhu Yong-Tian Zhu Si-Cheng Zou Fang Zuo National Astronomical Observatories Chinese Academy of Sciences Department of Astronomy Peking University Shanghai Astronomical Observatory Chinese Academy of Sciences Nanjing Institute of Astronomical Optics & Technology National Astronomical ObservatoriesChinese Academy of Sciences University of Science and Technology of China Department of Physics Applied Physics and AstronomyRensselaer Polytechnic InstituteTroyNY 12180USA Department of Physics and Astronomy Earlham CollegeRichmondIN 47374USA Universitt Heidelberg Zentrum für AstronomieLandessternwarteKnigstuhl 1269117 HeidelbergGermany Department of Astronomy Beijing Normal University Yunnan Observatories Chinese Academy of Sciences Purple Mountain Observatory Chinese Academy of Sciences

The Large sky Area Multi-Object Fiber Spectroscopic Telescope（LAMOST） general survey is a spectroscopic survey that will eventually cover approximately half of the celestial sphere and collect 10 million spectra of stars, galaxies and QSOs. Objects in both the pilot survey and the first year regular survey are included in the LAMOST DR1. The pilot survey started in October 2011 and ended in june 2012, and the data have been released to the public as the LAMOST Pilot Data Release in August 2012. The regular survey started in September 2012, and completed its first year of operation in june 2013. The LAMOST DR1 includes a total of 1202 plates containing 2 955 336 spectra, of which 1 790 879 spectra have observed signalto-noise ratio（SNR） ≥ 10. All data with SNR ≥ 2 are formally released as LAMOST DR1 under the LAMOST data policy. This data release contains a total of 2 204 696 spectra, of which 1 944 329 are stellar spectra, 12 082 are galaxy spectra and 5017 are quasars. The DR1 not only includes spectra, but also three stellar catalogs with measured parameters： late A,FGK-type stars with high quality spectra（1 061 918 entries）, A-type stars（100 073 entries）, and M-type stars（121 522 entries）. This paper introduces the survey design, the observational and instrumental limitations, data reduction and analysis, and some caveats. A description of the FITS structure of spectral files and parameter catalogs is also provided.

关键词： techniques: spectroscopic survey—data release—catalog

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Consensus statement on layout and delivery of automatic external defibrillator in China

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Journal of Hainan Medical University 2020年第15期26卷 18-23页

作者： Yu Cao Song Chen yan-Fen Chai xiao-Hui Chen Yu-guo Chen Shao-Wen Cheng Wen-Wei Cheng Bang-Han Ding yang Deng Jie Fu Bang-Jiang Fang Mai-ying Fan Li gui Ping Gong Wei guo Shu-bin guo Liang Huang Ji-Yuan Han Zhong Ji Xian-Fei Ji Xin-Cai Ji Hong-Xu Jin Xin-jun Jiang Wang-Xiang Jiang Jia-Liang liu xiao-Ran liu Zhi liu Chuan-Zhu Lv Feng Lu Tan-Shi Li Xin Li Yong Li Shang-Lun Li Shuang-Ming Li xiao-Gang Li Bao-jun Li Pei-Wu Li Chun-Sheng Li Zhi-jun Li Chang-luo Li Xiang-Min Li Yin-Ping Li Zong-jun Lu Zu-Xun Lu Zhong-Qiu Lu Zhi-Qian luo xiao-Xing Liao Jian-Bo Lei Tao Ma Yu Ma Yue-Feng Ma Qing-Bian Ma Lin-Hao Ma jun-Qi Ma Shi-Nan Nie Jie-Miao Ou-yang peng peng Qiao Pei Shu-Ming Pan guo-Zhong Qing Li-Jie Qin Wu-ying Qiao Fei Shao Wei Song Xing-Yue Song Zhen-Ju Song Rong-Ju sun De-Ya Shang du-Juan Sha gui-Lan Tao guo-Gang Tian ying-Ping Tian Jian-guang Tian Chao-yang Tong Zi-Ren Tang Meng-Xiong Tang guo-Ping Wu Zhi Wan Tao Wang Xin Wang peng Wang Zhong Wang Tong Wang Ri-Xing Wang Yi-Xin Wang xiao-dan Wang Ling Wu Wei Wei Hua Xiang Feng Xu jun Xu Jie Xu Miao-Rong Xie Shuo-gui Xu Tie Xu Feng Yu Wen Yi Li-Shan yang Shi-Jiao yan Jin-Jian Yao Shou-Chun yan Xue-Zhong Yu Xian-Zhi Ye Xian-Liang yan Fu-bing Zhou Rong-bin Zhou Ming Zhou Qiang Zhou Jin Zhou Ping Zhou Chang-Ju Zhu Hua-dong Zhu Ji-Hong Zhu Hong Zhang Mao Zhang Hua Zhang Na Zhang guo-Qiang Zhang guo-Xiu Zhang Jin-Song Zhang Wen-Wu Zhang Wen-Zhong Zhang Jian-Feng Zhang Yi-Min Zhu jun Zeng Yuan Zheng Zhi-Jie Zheng Shen Zhao yan Zhao Min Zhao bin Zhao xiao-dong Zhao xiao-Jing Zhao Hong-Ke Zeng Sheng-Qiang Zou The Chinese Society of Emergency Medicine Research Unit of Island Emergency Medicine Chinese Academy of Medical SciencesHainan Medical University Key Laboratory of Emergency and Trauma of Ministry of Education Hainan Medical UniversityHaikouHainanChina Emergency and Trauma College Hainan Medical UniversityHaikouHainanChina Department of Emergency Hainan Clinical Research Center for Acute and Critical DiseasesThe Second Affiliated Hospital of Hainan Medical UniversityHaikouHainanChina Key Laboratory of Hainan Trauma and Disaster Rescue Key Laboratory of Trauma of Hainan Medical University

*** Sudden cardiac death(SCD)refers to sudden death due to a variety of cardiac *** is manifested as a sudden loss of consciousness,cardiac arrest,and respiratory arrest and generally shows early symptoms that are atypical and not easily detected[1].According to a recent study,nearly 544000 patients suffer from SCD every year in China[2].

关键词： cardiac death respiratory

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