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Oncogenic osteomalacia caused by a phosphaturic mesenchymal tumor of the femur: A case report

World Journal of Clinical Cases 2019年第15期7卷 2081-2086页

作者： Dong Tang xiao-Man Wang Yong-Sheng Zhang xiao-xiao mi Department of Medical Imaging(Radiology) The Affiliated Hospital of Hangzhou Normal UniversityHangzhou 310015Zhejiang ProvinceChina Department of Ultrasound The Affiliated Hospital of Hangzhou Normal UniversityHangzhou 310015Zhejiang ProvinceChina Department of Radiology Hangzhou Hospital of Traditional MedicineHangzhou 310015Zhejiang ProvinceChina Department of Radiology The Second Affiliated Hospital of Zhejiang Chinese Medical UniversityHangzhou 310015Zhejiang ProvinceChina Institute of Translational Medicine The Affiliated Hospital of Hangzhou Normal UniversityHangzhou 310015Zhejiang ProvinceChina

BACKGROUND Oncogenic osteomalacia caused by phosphaturic mesenchymal tumors is very difficult to *** report a case of tumor-induced osteomalacia caused by a phosphaturic mesenchymal tumor of the left femur in a middle-aged woman after medical imaging and *** SUMMARY A 57-year-old woman presented with progressive bone pain for five *** was diagnosed with hypophosphatemic osteomalacia,as her laboratory data showed low serum phosphorus and low serum *** knee joint radiography revealed an osteolytic lesion of the left femur.A computed tomography scan showed mixed density shadows in the left *** resonance imaging of the left femur showed the presence of an oval area with a hypointense signal in T1-weighted magnetic resonance imaging(MRI)and highlow mixed signal in T2-weighted *** samples revealed the presence of short spindle cells,vascularization,and characteristics of phosphaturic mesenchymal *** resection was performed,and the clinical presentations and laboratory abnormalities were *** Diagnosis of oncogenic osteomalacia is difficult due to the varieties and localization of source tumors and absence of pathognomonic biomedical *** case highlights the importance of a combination of medical imaging and biopsy in the diagnosis of oncogenic osteomalacia caused by a phosphaturic mesenchymal tumor.

关键词： Oncogenic osteomalacia Phosphaturic mesenchymal tumor Hypophosphatemia Hypocalcemia Case report

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Hepatopulmonary metastases from papillary thyroid microcarcinoma:A case report

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World Journal of Clinical Cases 2022年第14期10卷 4661-4668页

作者： Chuan-Yu Yang Xuan-Wu Chen Dong Tang Wen-Jun Yang xiao-xiao mi Jun-Ping Shi Wei-Dong Du Department of Hepatobiliary Surgery The First Clinical Medical College of Zhejiang Chinese Medical UniversityHangzhou 310003Zhejiang ProvinceChina Department of Medical Imaging The Affiliated Hospital of Hangzhou Normal UniversityHangzhou 310015Zhejiang ProvinceChina Department of Pathology The Affiliated Hospital of Hangzhou Normal UniversityHangzhou 310015Zhejiang ProvinceChina Institute of Translational Medicine The Affiliated Hospital of Hangzhou Normal UniversityHangzhou 310015Zhejiang ProvinceChina

BACKGROUND Papillary thyroid carcinoma(PTC)is the most common endocrine *** thyroid microcarcinoma(PTMC)accounts for the majority of PTC ***,concurrent pulmonary and hepatic metastases of PTMC are rarely ***,we present a patient with coexisting liver and lung metastases from *** SUMMARY We describe a 26-year-old woman with PTMC with multiple concurrent *** 3 d of unexplained fever,she was admitted to our *** thyroid functional tests were *** positron emission tomography(PET)/magnetic resonance imaging(MRI)examination showed increased fluorodeoxyglucose(FDG)metabolism and space-occupying lesions in the left lobe of the ***,PET/MRI images revealed multiple nodules in the lung and liver with increased FDG *** computer tomography(CT)showed multiple pulmonary *** ultrasound and liver MRI showed multiple space-occupying lesions in the *** patient underwent total thyroidectomy and central lymph node *** pathological analysis showed a papillary microcarcinoma multiplex in the left lobe of the thyroid.A diagnosis of hepatopulmonary metastases from papillary thyroid microcarcinoma was *** patient was given iodine-131 treatment one year after the *** recovered well after the operation,and the incision healed *** discharge,she was treated with oral levothyroxine sodium tablets,and symptomatic and supportive treatments were also given to promote radioactive excretion and prevent bone marrow suppression by iodine-131 *** Since patients with thyroid cancer concurrent with hepatopulmonary metastases have rarely been reported,our case will highlight the clinical and pathological profiles of these patients.

关键词： Papillary thyroid microcarcinoma Distant metastasis Liver Lung Case report

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LJK-1 SPECIFICALLY INDUCES CANCER CELL APOPTOSIS BY GENERATING ROS AND CAUSING LONG-TERM TYROSINE PHOSPHORYLATION IMBALANCE

LJK-1 SPECIFICALLY INDUCES CANCER CELL APOPTOSIS BY GENERATI...

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2011医学科学前沿论坛第十二届全国肿瘤药理与化疗学术会议

作者： xiao-xiao Sun,mi-dan Ai,Ying Wang,Qiang Yu Departments of Pharmacology,Shanghai Institute of Materia Medica, Chinese Academy of Sciences,Shanghai,People’ s Republic of China

Introduction Diminishing ability of cells to undergo apoptosis is one of the major changes contributing to cancer development.(1 ) So,facilitating apoptosis in neoplastic cells has always been suggested as an important goal of anticancer drug development.(2;3) The aim of this study was to investigate the mechanisms of a small molecule compound LJK-1 in induction of tumor cell apoptosis.

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微Ti处理对低碳钢平面各向异性及织构的影响

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材料热处理学报 2002年第3期23卷 35-37页

作者：朱晓东宓小川俞宁峰宝山钢铁股份有限公司技术中心上海201900

研究了一定工艺条件下微Ti处理对冷轧退火钢板平面各向异性的影响 ,发现控制Ti含量可以改善钢板的平面各向异性。通过对Ti含量不同的钢板织构的比较 ,分析了Ti影响平面各向异性的机理。

关键词：微合金化平面各向异性织构钛低碳钢

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国家黑河流域综合治理工程生态成效科学评估

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中国科学院院刊 2017年第1期32卷 45-54页

作者：肖生春肖洪浪米丽娜李丽莉陆志翔彭小梅中国科学院西北生态环境资源研究院内陆河流域生态水文重点实验室兰州730000

黑河是我国西北地区第二大内陆河,2001年国家实施了该流域的综合治理工程。文章基于近10年来对黑河流域自然-经济系统水循环、水过程和生态与环境变化研究成果和阶段认识,对生态治理效果及其生态环境影响进行了科学评估。整体上,黑河流... 详细信息

黑河是我国西北地区第二大内陆河,2001年国家实施了该流域的综合治理工程。文章基于近10年来对黑河流域自然-经济系统水循环、水过程和生态与环境变化研究成果和阶段认识,对生态治理效果及其生态环境影响进行了科学评估。整体上,黑河流域水资源主要受西风带影响,主要产流区为中高山区。近10年和百年是流域器测记录以来和千年尺度上的丰水期,这为流域分水和综合治理提供了有力的水资源保障,而持续增长的社会经济系统水资源需求压力是导致流域中下游和经济发展-生态用水之间矛盾的主要根源。在中游地表水利用量得到有效控制的情况下,中游地区社会经济系统用水结构产生显著变化,但地表水资源限制和中游耕地面积持续增加导致局地地下水水位及储量呈减少趋势,且面临枯水期水资源严重超载问题。进入下游的水量接近规划要求,下游水系统和生态环境恶化趋势得到有效遏制,但还未全面恢复,并存在较大空间异质性;持续增加的由河岸林地开垦而来的耕地,对下游生态与生产用水分配带来更大的压力,下游需要更为精细的水资源时空管理和调控措施。在未来可能面临的枯水期,流域社会-经济-生态可持续发展目标下的水资源管理将面临更大的挑战。

关键词：黑河流域流域综合治理生态成效科学评估问题与对策

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Effect of Seed Layer on the Orientation of Zinc Oxide Film on Silicon Substrate

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Journal of Materials Science & Technology 2005年第6期21卷 887-890页

作者： mi xiao Makoto KUWABARA School of Electronic Information Engineering Tianjin University Tianjin 300072 China Department of Materials Science Tokyo University Tokyo Japan

The effect of seed layer on the orientation of ZnO film was investigated. Before the preparation of ZnO film using sol-gel method, seed layer of ZnO was prepared in a similar way using the precursor at a rather low concentration. Experiments show that the existence of seed layer can improve the orientation of the finally prepared ZnO film, while baking temperature, baking time and precursor concentration all have effects on the final results.

关键词： ZnO film Sol-gel Seed layer

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Hygrothermal ageing characterisation of epoxy resin based on transmission characteristics of microwave resonator with interdigital‐capacitor‐shaped defected ground structure

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High Voltage 2023年第6期8卷 1188-1195页

作者： mi xiao Wei Zhang Xuguang Wang Key Laboratory of the ministry of Education on Smart Power Grids School of Electrical and Information EngineeringTianjin UniversityTianjinChina

In this article,a method is proposed for the characterisation of epoxy resin thermal and hygrothermal ageing based on microwave resonator with interdigital‐capacitor‐shaped defected ground structure(IDCS‐DGS),which can realise rapid and simple non‐destructive testing of the ageing degree of epoxy resin *** resonant frequency of IDCS‐DGS was proved to decrease with the increase of dielectric constant of the around material by means of *** breakdown test at high voltage showed the deterio-ration of epoxy resin after hygrothermal ageing,which is caused by moisture absorption and hydrolysis *** addition,thermal ageing also caused a decline in the insulation per-formance of epoxy resin *** oxidation of epoxy resin samples at high temperatures produces polar molecules that increase the dielectric constant of the *** for the hygrothermal ageing samples,the entrance of polar water molecules will increase the dielectric constant of epoxy resin,and thus make an effect on the resonant frequency of IDCS‐*** tests of transmission performance show that after the hygrothermally aged epoxy resin samples were put on the microwave sensor,the resonant frequency decreased continuously with hygrothermal ageing time,and the deviations of resonant frequency are highly consistent with the weight variation rate of the samples.

关键词： resin thermal microwave

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Fatal risk in hysteroscopic surgery that should not be overlooked:Uterine artery pseudoaneurysm

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World Journal of Clinical Cases 2025年第8期13卷 53-56页

作者： mi-Si He Ke-xiao Yu Chen Wang Department of Gynecologic Oncology Chongqing University Cancer Hospital and Chongqing Cancer Institute and Chongqing Cancer HospitalChongqing 400030China Department of Orthopedics Chongqing Hospital of Traditional Chinese MedicineChongqing 400021China

This article provides a detailed account of the diagnosis and treatment of a case involving a uterine artery pseudoaneurysm(UAP),as well as an analysis of UAP *** finding emphasizes that UAP should be considered in patients presenting with abnormal genital bleeding after hysteroscopy and offers valuable insights and lessons for gynecologists in hysteroscopic *** patient underwent timely relevant examinations to confirm the diagnosis,allowing for crucial time required for her *** this study,the primary cause of UAP formation in the patient was attributed to a prior hysteroscopic surgical procedure conducted at another medical facility,suggesting that the selection and imple-mentation of dilatation catheters are some of the predisposing factors for *** conclusion,this case study offers a comprehensive analysis of the etiology of UAP and effectively provides timely diagnosis and treatment,offering valuable in-sights for the clinical diagnosis and management of UAP.

关键词： Editorial Uterine artery pseudoaneurysm Case report Hysteroscopic surgery Uterine arteriovenous malformations

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A Comprehensive Review of Isogeometric Topology Optimization:Methods,Applications and Prospects

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Chinese Journal of Mechanical Engineering 2020年第6期33卷 24-37页

作者： Jie Gao mi xiao Yan Zhang Liang Gao Department of Engineering Mechanics School of Aerospace EngineeringHuazhong University of Science and TechnologyWuhan430074China Hubei Key Laboratory for Engineering Structural Analysis and Safety Assessment Huazhong University of Science and TechnologyWuhan430074China The State Key Lab of Digital Manufacturing Equipment and Technology Huazhong University of Science and TechnologyWuhan430074China School of Machinery and Automation Wuhan University of Science and TechnologyWuhan430081China

Topology Optimization(TO)is a powerful numerical technique to determine the optimal material layout in a design domain,which has accepted considerable developments in recent *** classic Finite Element Method(FEM)is applied to compute the unknown structural responses in ***,several numerical deficiencies of the FEM significantly influence the effectiveness and efficiency of *** order to eliminate the negative influence of the FEM on TO,IsoGeometric Analysis(IGA)has become a promising alternative due to its unique feature that the Computer-Aided Design(CAD)model and Computer-Aided Engineering(CAE)model can be unified into a same mathematical *** the paper,the main intention is to provide a comprehensive overview for the developments of Isogeometric Topology Optimization(ITO)in methods and ***,some prospects for the developments of ITO in the future are also presented.

关键词： Topology optimization Isogeometric analysis CAD CAE

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Integrating MODIS LST and Sentinel-1 InSAR to monitor frozen soil deformation in the Qumalai-Zhiduo area, Qinghai-Tibet Plateau .

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International Journal of Digital Earth 2023年第1期16卷 1923-1943页

作者： Wenyan Yu mi Jiang xiao Cheng School of Geospatial Engineering and Science Sun Yat-sen UniversitySouthern Marine Science and Engineering Guangdong Laboratory(Zhuhai)ZhuhaiPeople’s Republic of China Key Laboratory of Comprehensive Observation of Polar Environment(Sun Yat-sen University) Ministry of EducationZhuhaiPeople’s Republic of China

Owing to continuous global warming,frozen soil degradation has become a universal phenomenon,leading to large-scale ground deformation that affects engineering construction and the fragile ecological *** observations,especially temporal InSAR,can quantify ground ***,the accuracy of InSAR modelling in capturing the spatial–temporal variability of the freeze–thaw process depends on the spatial resolution of temperature *** paper proposes a freeze–thaw amplitude model incorporating MODIS LST based on a single-master InSAR time-series deformation to calculate frozen soil *** applied this model to the Qumalai-Zhiduo area of the Qinghai-Tibet Plateau and compared its results with those of the model using weather station temperature in terms of frozen soil deformation parameters,RSME,and characteristic *** study found that the model incorporating MODIS LST performed better in areas far from weather stations,while both models produced similar results in areas of close ***,we evaluated another commonly used method for calculating frozen soil deformation parameters and found that the method incorporating MODIS LST based on a single-master time-series deformation is more accurate and precise than the method based on a multi-master SBAS network.

关键词： InSAR deformation monitoring Qinghai Tibet plateau MODIS LST frozen soil

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