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Investigation of oil and water migrations in lacustrine oil shales using 20 MHz 2D NMR relaxometry techniques

Petroleum Science 2022年第3期19卷 1007-1018页

作者： Bo Liu xiao-wen jiang Long-Hui Bai Rong-Sheng Lu jiangsu Key Laboratory for Design and Manufacture of Micro-Nano Biomedical Instruments Southeast UniversityNanjingJiangsu 211189China State Key Laboratory Cultivation Base for Accumulation and Development of Unconventional Oil and Gas Northeast Petroleum UniversityDaqingHeilongjiang 163318China School of Mechanical Engineering Southeast UniversityNanjingJiangsu 211189China State Key Laboratory of Bioelectronics Southeast UniversityNanjingJiangsu 211189China

The behavior of oil and water in tight rocks can change the distribution of oil or water in pores,which affects the production of crude *** Magnetic Resonance(NMR)method is an effective and nondestructive tool for evaluating rocks with comparison and analysis both quantitatively and *** our study,20 MHz NMR Relaxometry is used as a key technique to study the changes of water and oil behaviors in Chinese lacustrine Qingshankou shales under different saturated states(imbibition and evaporation without pressure).The results show that variation in different proton populations(water,oil and organic)can be distinguished using 2D T_(1)-T_(2)*** comparison among T_(1)-T_(2)maps with different saturated states shows that different signal regions changed during oil and water migrations,which the 1D NMR Relaxometry may be not easy to *** with the pyrolysis analysis,T2 shift and differences of signal regions in T_(1)-T_(2)maps can reflect properties such as wettability and composition(organic matter,clay and magnetic minerals)to some *** study provides better insight into oil and water behaviors in lacustrine oil shales with further understanding of 20 MHz NMR 2D T_(1)-T_(2)maps both in qualitative and quantitative analysis.

关键词： NMR Relaxometry Lacustrine oil shales Oil and water migrations T_(1)-T_(2)map

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Acetyl-11-keto-β-boswellic acid extracted from Boswellia serrata promotes Schwann cell proliferation and sciatic nerve function recovery

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Neural Regeneration Research 2018年第3期13卷 484-491页

作者： xiao-wen jiang bin-qing zhang lu qiao lin liu xue-wei wang wen-hui yu Department of Veterinary Medicine Northeast Agricultural University Harbin Helongjiang Province China

Frankincense can promote blood circulation. Acetyl-11-keto-β-boswellic acid （AKBA） is a small molecule with anti-inflammatory properties that is derived from Boswellia serrata. Here, we hypothesized that it may promote regeneration of injured sciatic nerve. To address this hypothesis, we established a rat model of sciatic nerve injury using a nerve clamping method. Rats were administered AKBA once every 2 days at doses of 1.5, 3, and 6 mg/kg by intraperitoneal injection for 30 days from the 1st day after injury. Sciatic nerve function was evaluated using the sciatic functional index. Degree of muscle atrophy was measured using the triceps surae muscle Cuadros *** changes were observed by hematoxylin-eosin staining. Western blot analysis was used to detect expression of phospho-extracellular signal-regulated kinase 1 and 2 （p-ERK1/2） in injured nerve. S100 immunoreactivity in injured nerve was detected by immunohistochemistry. In vivo experiments showed that 3 and 6 mg/kg AKBA significantly increased sciatic nerve index, Cuadros index of triceps muscle, p-ERK1/2 expression, and S100 immunoreactivity in injured sciatic nerve of sciatic nerve injury model rats. Furthermore,for in vitro experiments, Schwann cells were treated with AKBA at 0–20 μg/mL. Proliferation of Schwann cells was detected by Cell Counting Kit-8 colorimetry assay. The results showed that 2 μg/mL AKBA is the optimal therapeutic concentration. In addition, ERK phosphorylation levels increased following 2 μg/mL AKBA treatment. In the presence of the ERK1/2 inhibitor, PD98059 （2.5 μL/mL）, the AKBA-induced increase in p-ERK1/2 protein expression was partially abrogated. In conclusion, our study shows that AKBA promotes peripheral nerve regeneration with ERK protein phosphorylation playing a key role in this process.

关键词： nerve regeneration acetyl-11-keto-β-boswellic acid peripheral nerve injury repair sciatic nerve crush injury Schwann cells cell proliferation ERK signaling pathway PD98059 neural regeneration

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Acetyl-11-keto-beta-boswellic acid promotes sciatic nerve repair after injury: molecular mechanism

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Neural Regeneration Research 2022年第12期17卷 2778-2784页

作者： Yao Wang Zong-Liang Xiong Xiang-Lin Ma Chong Zhou Mo-Han Huo xiao-wen jiang wen-Hui Yu Department of Veterinary Medicine Northeast Agricultural UniversityHarbinHeilongjiang ProvinceChina College of Life Sciences Northeast Agricultural UniversityHarbinHeilongjiang ProvinceChina Key Laboratory of Heilongjiang Education Department for Common Animal Disease Prevention and Treatment Northeast Agricultural UniversityHarbinHeilongjiang ProvinceChina Institute of Chinese Veterinary Medicine Northeast Agricultural UniversityHarbinHeilongjiang ProvinceChina

Previous studies showed that acetyl-11-keto-beta-boswellic acid(AKBA),the active ingredient in the natural Chinese medicine Boswellia,can stimulate sciatic nerve injury repair via promoting Schwann cell ***,the underlying molecular mechanism remains poorly *** this study,we performed genomic sequencing in a rat model of sciatic nerve crush injury after gastric AKBA administration for 30 *** found that the phagosome pathway was related to AKBA treatment,and brain-derived neurotrophic factor expression in the neurotrophic factor signaling pathway was also highly *** further investigated gene and protein expression changes in the phagosome pathway and neurotrophic factor signaling *** expression in the phagosome pathway was markedly decreased,and brain-derived neurotrophic factor,nerve growth factor,and nerve growth factor receptor expression levels in the neurotrophic factor signaling pathway were greatly ***,expression levels of the inflammatory factors CD68,interleukin-1β,pro-interleukin-1β,and tumor necrosis factor-αwere also *** basic protein-andβ3-tubulin-positive expression as well as the axon diameter-to-total nerve diameter ratio in the injured sciatic nerve were also *** findings suggest that,at the molecular level,AKBA can increase neurotrophic factor expression through inhibiting myeloperoxidase expression and reducing inflammatory reactions,which could promote myelin sheath and axon regeneration in the injured sciatic nerve.

关键词： AKBA axon genomics inflammatory injury and repair myelin sheath myeloperoxidase neurotrophic factor peripheral nerve phagosome pathway regeneration Sprague-Dawley rat

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Neuroprotective effects of kukoamine A on 6-OHDA-induced Parkinson’s model through apoptosis and iron accumulation inhibition

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Chinese Herbal Medicines 2021年第1期13卷 105-115页

作者： Xin Li xiao-wen jiang Hai-xiao Chu Qing-chun Zhao Huai-wei Ding Chao-hong Cai Department of Pharmacy General Hospital of Northern Theater CommandShenyang 110840China Key Laboratory of Structure-Based Drug Design and Discovery Ministry of EducationShenyang Pharmaceutical UniversityShenyang 110016China Department of Traditional Chinese Medicine Shenyang Pharmaceutical UniversityShenyang 110016China

Objective: Parkinson’s disease(PD) is characterized by the loss of dopaminergic neurons in substantia nigra(SN). Our previous study demonstrated kukoamine A(KuA) to exhibit strong neuroprotective effects through antioxidative stress, and autophagy in MPTP/MPP+-induced PD models in vivo and in vitro. It is necessary to evaluate the efficacy of the anti-PD effects under various ***: In the present study, total chemical synthesis was used to obtain KuA, which performed low content in Lycii Cortex. Then, 6-OHDA-induced PD model of PC12 cells was used to investigate the effects of KuA on ***: Our results demonstrated that KuA ameliorated cell loss and mitochondrial membrane potential(MMP) loss, and inhibited Bax/Bcl-2 ratio increase that were induced by 6-OHDA. Iron accumulation in SN is thought to participate in neuronal death in PD, which subsequently resulted in oxidative stress and overexpression of a-synuclein caused by iron metabolism protein disorder. In our study, KuA could chelate cellular iron content and decrease iron influx. Moreover, KuA could upregulate the expression of ferroportin1 and Hephaestin, downregulate the expression of DMT1, TfR, and Ferritin to maintain cellular iron homeostasis avoiding neuronal death from cellular iron deposition. Moreover, KuA could decrease the expression of a-synuclein in cells. All the results indicated that KuA protected against neurotoxininduced PD due to the apoptosis inhibition and iron homeostasis ***: KuA treatment might represent a neuroprotective treatment for PD.

关键词： 6-OHDA iron chelation iron homeostasis kukoamine A neuroprotection Parkinson’s disease

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A Model of Competition with Environmental Taxes and Regulation Under Conditions of Oligopoly

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Systems Science and Systems Engineering 2002年第3期11卷 275-279页

作者： xiao jiang-wen, LUO Yun-feng, ZHAO Yong, YUE Chao-yuanInstitute of Systems Engineering, Huazhong University of Science and Technology, Wuhan 430074, China Institute of Systems Engineering Huazhong University of Science and Technology Wuhan 430074 China

The Cournot static game with complete information is reviewed. A model of competition with environmental taxes under conditions of oligopoly is built based on the Cournot game, and some helpful conclusions are drawn from the model. A game model with regulation of government is also established. Finally the optimization problem of market structure is discussed.

关键词： game theory Cournot model oligopoly tax regulation

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环形直流微电网的二次控制与稳定性分析

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控制理论与应用 2021年第7期38卷 979-987页

作者：刘骁康王燕舞肖江文华中科技大学人工智能与自动化学院湖北武汉430074 华中科学大学图像信息处理与智能控制教育部重点实验室湖北武汉430074

本文阐述了一种环形直流微电网系统分布式二次控制的稳定性分析方法,实现了微网系统的电压调控和电流分配.首先,借助多智能体系统的一致性算法,设计了局部观测器来估计所有分布式能源节点的平均电压.然后,基于观测器状态和邻居节点的电... 详细信息

本文阐述了一种环形直流微电网系统分布式二次控制的稳定性分析方法,实现了微网系统的电压调控和电流分配.首先,借助多智能体系统的一致性算法,设计了局部观测器来估计所有分布式能源节点的平均电压.然后,基于观测器状态和邻居节点的电流信息设计了融合误差和动态反馈控制器,并通过解耦潮流代数方程得到了关于融合误差的闭环系统.进一步基于图论、线性系统理论和矩阵特征值扰动分析方法,得到了闭环系统的稳定性条件.最后,在环形直流微电网的仿真平台上验证了该方法的有效性.

关键词：微电网分布式控制电压调控多智能体系统二次控制

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Antibiotic prophylaxis in third molar surgery:a systematic review and meta-analysis

Antibiotic prophylaxis in third molar surgery:a systematic r...

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中华口腔医学会第14次全国口腔医学学术会议（2012年会）

作者： College of Stomatology,Shanghai Jiao Tong University(Shanghai 200011,China) wen xiao,Wei-wen jiang

Background:The use of antibiotic prophylaxis in third molar surgery is still under *** aim of this meta-analysis was to assess the effect of antibiotic prophylaxis in patients undergoing third molar extraction with respect to incidence of postoperative infection. Methods:A literature search was conducted in databases of MEDLINE,EMBASE, and Cochrane Central Register of Controlled *** selection,data extraction, quality assessment,and meta-analysis were conducted according to the recommendations by Cochrane collaboration. Results:Ten randomized controlled trials were *** infection occurred in 108/1,402(7.7%)patients in the treatment group and in 155/991(15.6%) patients in the control *** antibiotic therapy was effective in reducing the risk of postoperative infection(odds ratio,0.29;95%confidence interval,0.21-0.41;P<0.001). Conclusions:Antibiotics prophylaxis reduced the risk of postoperative *** patients with the systemic disease were recommended to have evaluation of basic health status before third molar surgery.

关键词： antibiotic prophylaxis third molar surgery meta-analysis

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安庆长江铁路大桥4号墩斜拉索挂设施工

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桥梁建设 2013年第5期43卷 18-22页

作者：童林鸿肖江文王林中铁大桥局宁安铁路安庆长江大桥工程指挥部安徽安庆246008 中铁大桥局集团第二工程有限公司江苏南京210015

安庆长江铁路大桥主桥为(101.5+188.5+580+217.5+159.5+116)m双塔三索面钢桁梁斜拉桥,该桥斜拉索采用热挤聚乙烯7mm热镀锌钢丝拉索,斜拉索最长301.750m,单根索最重37.3t。由于该桥4号墩需部分采用塔梁同步施工,为实现快速、安全挂设... 详细信息

安庆长江铁路大桥主桥为(101.5+188.5+580+217.5+159.5+116)m双塔三索面钢桁梁斜拉桥,该桥斜拉索采用热挤聚乙烯7mm热镀锌钢丝拉索,斜拉索最长301.750m,单根索最重37.3t。由于该桥4号墩需部分采用塔梁同步施工,为实现快速、安全挂设斜拉索,成盘索采用塔吊及架梁吊机提升上桥;在主边跨上桁面设置展索通道,通过塔吊、塔顶吊架2种起吊方式完成塔端提升挂设;索体脱空后在上桁面展索,短索、中索利用导向系统与卷扬机配合完成梁端安装,长索利用导向系统、卷扬机牵引系统及软牵引系统配合完成梁端安装;同步对称分级完成塔端1组(6根)斜拉索的张拉施工。目前,该桥4号墩斜拉索已全部挂设并初步张拉完成。

关键词：铁路桥,斜拉桥斜拉索施工技术桥梁施工

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实施最优排污权配置

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系统工程理论与实践 2010年第12期30卷 2151-2156页

作者：刘昌臣肖江文罗云峰华中科技大学系统工程研究所武汉430074

对不完全信息下的最优排污权配置问题进行研究,设计了相应的实施机制——修改的Duggan机制.研究表明:该机制不仅实施了排污权的最优配置,而且在均衡路径上厂商缴纳的排污税总额等于排污造成的社会成本,达到预算平衡.此外,讨论了社会成... 详细信息

对不完全信息下的最优排污权配置问题进行研究,设计了相应的实施机制——修改的Duggan机制.研究表明:该机制不仅实施了排污权的最优配置,而且在均衡路径上厂商缴纳的排污税总额等于排污造成的社会成本,达到预算平衡.此外,讨论了社会成本函数不可微、排污权最优配置为非内点解以及厂商地位不平等的情况下,排污权的最优配置实施机制.

关键词：最优排污权配置实施机制设计

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社区产消者能量分享研究综述

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控制与决策 2020年第10期35卷 2305-2318页

作者：王燕舞崔世常肖江文施阳华中科技大学人工智能与自动化学院武汉430074 华中科技大学图像信息处理与智能控制.教育部重点实验室武汉430074 维多利亚大学机械工程系维多利亚市V8W3P6

随着可再生能源和智能电网技术的发展,能源产消者作为一类新型终端用户,已在能源优化与管理方面表现出更为主动灵活的作用,对提高社区能源效率、提升能源经济性和改善本地配电网稳定性具有重要影响.首先,总结了常见的社区能源产消者类... 详细信息

随着可再生能源和智能电网技术的发展,能源产消者作为一类新型终端用户,已在能源优化与管理方面表现出更为主动灵活的作用,对提高社区能源效率、提升能源经济性和改善本地配电网稳定性具有重要影响.首先,总结了常见的社区能源产消者类型及其特点,指出其在智能电网需求侧实现能源优化的灵活性和潜在价值;其次,剖析了社区能量分享的典型模式,归纳了各自的基本特征、优势与局限性;然后,在此基础上探讨了社区产消者能量分享涉及的能源数据预测方法、博弈问题均衡分析及分布式优化算法;最后,对社区产消者能量分享的前瞻性难点问题进行了展望,以期为相关研究提供参考.

关键词：能源产消者能量分享模式设计博弈优化预测

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