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Etiology,diagnosis, management and outcomes of epiphora referrals to an oculoplastic practice

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International Journal of Ophthalmology(English edition) 2016年第12期9卷 1751-1755页

作者： Guang-Lin Shen John D.Ng xiao-ping ma Department of Ophthalmology Zhongshan Hospital of Fudan University Casey Eye Institute Oregon Health and Science University

AIM： To investigate the etiology, diagnosis, management and outcome of epiphora referrals to an oculoplastic ***： Retrospective chart review of patients referred for epiphora to an oculoplastic clinic between 2005 and 2009. Patient demographics, past history, ophthalmic examination, treatment and outcome were ***： There were 237 subjects with a primary complaint of epiphora. They included 130 （55%） females and 107 （45%） males with an average age of 55.9±25.9y. The most common cause of epiphora was lacrimal obstruction （46%）; followed by multifactorial epiphora （22%）, reflex tearing （22%） and eyelid malposition （11%）. Differences in prevalence of etiology were noted in terms of age and gender distribution. Of the 182 （77%） patients who returned for follow up, 41 （23%） reported a complete resolution and 102 （56%） reported a significant improvement in their ***： Epiphora is a common condition with many causes. A thorough history and examination are required to provide the appropriate treatment tailored to the underlying cause.

关键词： epiphora etiology lacrimal disease dry eye

Nanocavity-Mediated Fast magnetic Vortex Core In-Situ Switching by Local magnetic Field

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Chinese Physics Letters 2021年第12期38卷 76-79页

作者： xiao-ping ma Hongguo Yang Changfeng Li Cheng Song Hong-Guang Piao Hubei Engineering Research Center of Weak magnetic-Field Detection College of ScienceChina Three Gorges UniversityYichang 443002China Key Laboratory of Advanced materials(MOE) School of Materials Science and EngineeringTsinghua UniversityBeijing 100084China

Fast in situ switching of magnetic vortex core in a ferromagnetic nanodisk assisted by a nanocavity,with diameter comparable to the dimension of a vortex core,is systematically investigated by changing the strength as well as the diameter of the effective circular region of the applied magnetic *** applying a local magnetic field within a small area at the nanodisk center,fast switching time of about 35 ps is achieved with relatively low field strength(70 mT)which is beneficial for fast data reading and *** reason for this phenomenon is that the magnetic spins around the nanocavity is aligned along the cavity wall due to the shape anisotropy when the perpendicular field is applied,which deepens the dip around the vortex core,and thus facilitates the vortex core switching.

关键词： strength cavity vortex

Melatonin concentrations in serum of primary glaucoma patients

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International Journal of Ophthalmology(English edition) 2018年第8期11卷 1337-1341页

作者： xiao-ping ma man-Yi Shen Guang-Lin Shen Qiao-Ran Qi Xing-Huai Sun Department of Ophthalmology Zhongshan HospitalFudan University Department of Ophthalmology Eye & Ent Hospital of Fudan University

AIM： To determine whether glaucoma patients exhibit an abnormal melatonin concentration in serum and the effects of psychiatric disorders caused by glaucoma in melatonin ***： A sample of 80 primary angle-closure glaucoma（PACG） patients, 120 primary open angle glaucoma（POAG） patients, and 120 normal controls were enrolled in this study. All the participants were asked to complete the following questionnaires： Pittsburgh sleep quality index（PSQI）, self-rating anxiety scale（SAS）, and self-rating depression scale（SDS）. Variance analysis was used to compare the subscores between the groups. After that, we chose 58 patients with primary glaucoma and 20 nonglaucoma control patients to collect their serum samples at 7-10 a.m. Serum melatonin levels were measured using enzyme linked immunosorbent assay（ELISA）. RESULTS： Of all participants, the scores of PSQI, SAS, and SDS in PACG and POAG group were 9.38±0.40, 46.08±8.99, 51.11±10.72 and 7.43±0.35, 45.42±9.87, 49.04±12.24 respectively, significantly higher than those in control group（4.16±0.28, 35.49±9.18, 40.31±13.08）. The serum melatonin levels in PACG（37.29±2.99 pg/mL） and POAG（35.97±3.64 pg/mL） were significantly higher than the controls（29.96±3.94 pg/m L）（P〈0.001）. But no difference was found between the PACG and POAG（P=0.216）. Glaucoma patients with sleep disorders, anxiety and depression were more likely resulting in the increase of melatonin ***： There is a significant increase in serum melatonin levels in glaucoma patients compared to the controls especially in glaucoma patients with psychiatric disorders such as sleep disorders, anxiety and depression.

关键词： glaucoma melatonin circadian rhythm sleepdisorder anxiety depression

Accelerated oxygen evolution kinetics on Ir-doped SrTiO_(3) perovskite by NH_(3) plasma treatment

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Chinese Physics B 2022年第11期31卷 611-618页

作者： Li-Li Deng xiao-ping ma man-Ting Lu Yi He Rong-Lei Fan Yu Xin School of Physical Science and Technology Jiangsu Key Laboratory of Thin FilmsSoochow UniversitySuzhou 215006China

Exploring low-cost and high-performance catalysts for oxygen evolution reaction(OER)remains to be a great ***-based perovskite oxide has large potential in OER because of its intrinsic activity and outstanding physicochemical *** this study,iridium-doped strontium titanate(Ir-STO)solution is brushed on a Ti sheet by the traditional method to obtain the Ir-STO/Ti electrodes after being calcined at a high *** microstructure and electrocatalysis properties of the Ir-STO are further modified by a facile and scalable NH_(3)-plasma *** addition to the doping of Ir,the NH_(3) plasma treatment further results in N-doping into Ir-STO,which enriches active species and causes oxygen vacancies near doped *** resulting N,Ir-STO/Ti electrode reveals excellent acidic OER activity with the lowest overpotential of 390 m V at 10 m A/cm^(2) and the smallest Tafel slope of 140 mV/dec after 10-min plasma ***,the great potential of activated N,Ir-STO/Ti is regarded as a catalyst for the OER,and thus making a new opportunity for developing other perovskite catalysts via NH_(3) plasma treatment.

关键词： electrocatalysts NH_(3)plasma oxygen vacancies N doping

Asymmetric dynamic behaviors of magnetic domain wall in trapezoid-cross-section nanostrip

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Chinese Physics B 2020年第9期29卷 518-522页

作者： xiao-ping ma Hong-Guang Piao Lei Yang Dong-Hyun Kim Chun-Yeol You Liqing Pan Research Institute for magnetoelectric&Weak magnetic-field Detection College of ScienceChina Three Gorges UniversityYichang 443002China Department of Physics Chungbuk National UniversityCheongju 28644ChungbukRepublic of Korea Department of Emerging materials Science Daegu Gyeongbuk Institute of Science and Technology(DGIST)Daegu 42988Republic of Korea

Field-driven magnetic domain wall propagation in ferromagnetic nanostrips with trapezoidal cross section has been systematically investigated by means of micromagnetic simulation. Asymmetric dynamic behaviors of domain wall, depending on the propagation direction, were observed under an external magnetic field. When the domain walls propagate in the opposite direction along the long axis of the nanostrip, the Walker breakdown fields as well as the average velocities are different. The asymmetric landscape of demagnetization energies, which arises from the trapezoidal geometry, is the main origin of the asymmetric propagation behavior. Furthermore, a trapezoid-cross-section nanostrip will become a nanotube if it is rolled artificially along its long axis, and thus a two-dimensional transverse domain wall will become a three-dimensional one. Interestingly, it is found that the asymmetric behaviors observed in two-dimensional nanostrips with trapezoidal cross section are similar with some dynamic properties occurring in three-dimensional nanotubes.

关键词： ferromagnetic nanowire magnetic domain wall geometric effect asymmetric Walker breakdown

Polarity-controllable magnetic skyrmion filter

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Chinese Physics B 2024年第10期33卷 400-404页

作者： xiao-Lin Ai Hui-Ting Li Xue-Feng Zhang Chang-Feng Li Je-Ho Shim xiao-ping ma Hong-Guang Piao Hubei Engineering Research Center of Weak magnetic-Field Detection College of ScienceChina Three Gorges UniversityYichang 443002China Department of Physics College of ScienceYanbian UniversityYanji 133002China

The skyrmion generator is one of the indispensable components for the future functional skyrmion devices,but the process of generating skyrmion cannot avoid mixing with other magnetic textures,such as skyrmionium and nested skyrmion *** mixed magnetic textures will inevitably lead to the blockage of skyrmion transport and even the distortion of data ***,the design of an efficient skyrmion filter is of great significance for the development of skyrmion-based spintronic *** this work,a skyrmion filter scheme is proposed,and the high-efficiency filtering function is demonstrated by micromagnetic *** results show that the filtering effect of the scheme depends on the structure geometry and the spin current density that drives the *** on this scheme,the polarity of the filtered skyrmion can be controlled by switching the magnetization state at the output end,and the“cloning”of the skyrmion can be realized by geometric optimization of the *** believe that in the near future,the skyrmion filter will become one of the important components of skyrmion-based spintronic devices in the future.

关键词： spintronics skyrmions skyrmion filter skyrmion polarity skyrmion clone

Effects of Bifidobacterium lactis BLa80 on fecal and mucosal flora and stem cell factor/c-kit signaling pathway in simulated microgravity rats

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World Journal of Gastroenterology 2025年第1期31卷 93-109页

作者： ping Zhang Ying Zhu Pu Chen Tong Zhou Zhe-Yi Han Jun xiao Jian-Feng ma Wen ma Peng Zang Ying Chen Graduate School Hebei North UniversityZhangjiakou 075000Hebei ProvinceChina Key Laboratory of Aerospace Nutrition and Food Engineering China Astronaut Research and Training CenterBeijing 100094China Department of Gastroenterology The Air Force Medical CenterBeijing 100142China Department of Blood Transfusion Air Force Medical CenterBeijing 100142China

BACKGROUND Simulated microgravity environment can lead to gastrointestinal motility *** pathogenesis of gastrointestinal motility disorders is closely related to the stem cell factor(SCF)/c-kit signaling pathway associated with intestinal flora and Cajal stromal ***,intestinal flora can also affect the regulation of SCF/c-kit signaling pathway,thus affecting the expression of Cajal stromal *** cells are the pacemakers of gastrointestinal *** To investigate the effects of Bifidobacterium lactis(***)BLa80 on the intestinal flora of rats in simulated microgravity and on the gastrointestinal motility-related SCF/c-kit *** The internationally recognized tail suspension animal model was used to simulate the microgravity environment,and 30 rats were randomly divided into control group,tail suspension group and drug administration tail suspension group with 10 rats in each group for a total of 28 *** tail group was given *** BLa80 by intragastric administration,and the other two groups were given water intragastric administration,the concentration of intragastric administration was 0.1 g/mL,and each rat was 1 mL/***&eosin staining was used to observe the histopathological changes in each segment of the intestine of each group,and the expression levels of SCF,c-kit,extracellular signal-regulated kinase(ERK)and p-ERK in the gastric antrum of each group were detected by Western blotting and *** fecal flora and mucosal flora of rats in each group were detected by 16S *** Simulated microgravity resulted in severe exfoliation of villi of duodenum,jejunum and ileum in rats,marked damage,increased space between villi,loose arrangement,shortened columnar epithelium of colon,less folds,narrower mucosal thickness,reduced goblet cell number and crypts,and significant improvement after probiotic *** microgravity reduced the expressions of SCF and c-kit,and increased the express

关键词： Simulated microgravity Rat Intestinal flora Gastrointestinal motility Stem cell factor/c-kit signaling pathway

Multiple magnetic Phase Transitions and Critical Behavior in Single-Crystal SmMn_(2)Ge_(2)

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Chinese Physics Letters 2023年第6期40卷 77-83页

作者：王小艳林浚发曾祥雨王欢马小平王乙婷韩坤夏天龙 Department of Physics Renmin University of ChinaBeijing 100872China Beijing Key Laboratory of Opto-electronic Functional materials&Micro-nano Devices Renmin University of ChinaBeijing 100872China Key Laboratory of Quantum State Construction and manipulation(Ministry of Education) Renmin University of ChinaBeijing 100872China Laboratory for Neutron Scattering Renmin University of ChinaBeijing 100872China

magnetic materials with noncollinear spin configurations have engendered significant interest in condensed matter physics due to their intriguing physical *** direct our attention towards the magnetic properties and critical behavior of single-crystal SmMn_(2)Ge_(2),an itinerant magnet with numerous temperature-dependent magnetic phase ***,SmMn_(2)Ge_(2)displays significant magnetic anisotropy with easy magnetization direction switching from the c axis to the ab plane as temperature *** critical behavior of the ferromagnetic transition occurring above room temperature is thoroughly *** and self-consistent critical exponents,includingβ=0.292(2),γ=0.924(8),andδ=4.164(6),along with the Curie temperature T_c=347 K,are extracted through various methods,which provide evidence for the coexistence of multiple magnetic interactions in SmMn_(2)Ge_(2).Further analysis reveals that the magnetic interaction of SmMn_(2)Ge_(2)is a long-range type with the interaction distance decaying as J(r)~r^(-4.35).

关键词： critical Transition interaction

Asymmetric scattering behaviors of spin wave dependent on magnetic vortex chirality

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Chinese Physics B 2023年第10期32卷 635-640页

作者：张雪枫沈帝虎马晓萍宋成于海明朴红光 Hubei Engineering Research Center of Weak magnetic-Field Detection China Three Gorges UniversityYichang 443002China Department of Physics College of ScienceYanbian UniversityYanji 133002China Key Laboratory of Advanced materials(MOE) School of Materials Science and EngineeringTsinghua UniversityBeijing 100084China Fert Beijing Institute School of Integrated Circuit Science and EngineeringBeijing Advanced Innovation Center for Big Data and Brain ComputingBeihang UniversityBeijing 100191China

We investigate asymmetric spin wave scattering behaviors caused by vortex chirality in a cross-shaped ferromagnetic system by using the micromagnetic *** the system,four scattering behaviors are found:(i)asymmetric skew scattering,depending on the polarity of vortex core,(ii)back scattering(reflection),depending on the vortex core stiffness,(iii)side deflection scattering,depending on structural symmetry of the vortex circulation,and(iv)geometrical scattering,depending on waveguide *** first and second scattering behaviors are attributed to nonlinear topological magnon spin Hall effect related to magnon spin-transfer torque effect,which has value for magnonic exploration and application.

关键词： magnonics magnetic vortex spin wave magnetic chirality