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Risk factors and care of early surgical site infection after primary posterior lumbar interbody fusion

Frontiers of Nursing 2023年第2期10卷 203-211页

作者： xiao-lin zuo Yan Wen Orthopedic trauma Luohe Central Hospital(The First Affiliated Hospital of Luohe Medical College)LuoheHenan 462000China Department of Nursing Luohe Central Hospital(The First Affiliated Hospital of Luohe Medical College)LuoheHenan 462000China

Objectives:To explore the risk factors and nursing measures of early surgical site infection(SSI)after posterior lumbar interbody fusion(PLIF).Methods:A total of 468 patients who received PLIF in our hospital from January 2017 to June 2020 were enrolled into this *** to the occurrence of early SSI,the patients were divided into two groups,and the general data were analyzed by univariate *** logistic regression analysis was conducted with the dichotomous variable of whether early SSI occurred and other factors as independent variables to identify the risk factors of early SSI and put forward targeted prevention and nursing ***:Among 468 patients with PLIF,18 patients developed early SSI(3.85%).The proportion of female,age,diabetes mellitus and urinary tract infection(UTI),operation segment,operation time,post-operative drainage volume,and drainage time were significantly higher than those in the uninfected group,with statistical significance(P0.05).Logistic regression analysis showed that preoperative diabetes mellitus(OR=2.109,P=0.012)/UTI(OR=1.526,P=0.035),prolonged drainage time(OR=1.639,P=0.029)were risk factors for early ***(OR=0.736,P=0.027)and albumin level(OR=0.526,P=0.004)were protective factors in reducing early ***:Women,preoperative diabetes/UTI,hypoproteinemia,and prolonged drainage time are risk factors for early SSI after *** effective preventive measures should be taken in combination with targeted nursing intervention to reduce the risk of early SSI.

关键词： incisional infection nursing measures posterior lumbar interbody fusion risk factors multivariate regression analysis

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A care bundle for pressure ulcer treatment in intensive care units

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International Journal of Nursing Sciences 2015年第4期2卷 340-347页

作者： xiao-lin zuo Fan-Jie Meng Graduate School Tianjin University of Traditional Chinese MedicineTianjin 300193China School of Nursing Tianjin University of Traditional Chinese MedicineTianjin 300193China

Pressure ulcers(PUs)are localized injuries of the skin or underlying tissue caused by prolonged pressure,exposure to shear forces or *** represent a major concern for hospitalized patients and the health professionals responsible for their *** care init(ICU)patients are at high risk of PU development,and the development of PUs can significantly extend the length of time a patient must remain in the *** with PUs experience significantly increased morbidity,mortality and financial burden.A significant amount of evidence has accumulated indicating that PU prevention is an essential component of patient ***,standardized guidelines and protocols for PU prevention in ICUs have not been universally *** review aims to describe and analyze an optimized PU prevention care bundle based on the best available evidence and existing national *** distilled the available information into five main topics important for PU prevention:Risk Assessment,Skin Assessment,Support Surfaces,Nutrition and *** larger scale studies are needed to clinically verify the effectiveness of the care bundle.

关键词： Pressure ulcer Care bundle Intensive care unit

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Effects of yoga on negative emotions in patients with breast cancer:A meta-analysis of randomized controlled trials

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International Journal of Nursing Sciences 2016年第3期3卷 299-306页

作者： xiao-lin zuo Qi Li Fan Gao lin Yang Fan-Jie Meng Graduate College Tianjin University of Traditional Chinese MedicineTianjin 300193China General Department of Internal Medicine Tianjin HospitalTianjin 300211China School of Nursing Tianjin University of Traditional Chinese MedicineTianjin 300193China

Objective:The study aims to investigate the effectiveness of yoga on negative emotions in breast cancer ***:Pubmed,Elsevier,Web of Science,Cochrane Library,CBM,CNKI,Wanfang,and VIP databases were screened throughout October *** control trials(RCTs)examining the effects of yoga versus a non-exercise or waitlist control group on negative moods in breast cancer patients were *** methodological quality of included RCTs was evaluated by using the Cochrane Handbook 5.1,and data were analyzed using the Review Manager ***:A total of 21 RCTs with 1762 participants were *** found evidence for immediate effects on anxiety(p<0.00001),depression(p<0.00001),distress(p<0.00001),perceived stress(p<0.00001),and emotional well-being(p=0.0002).Sustained effects(3 months)were only found in depression(p=0.004)but not anxiety(p=0.43),and other outcomes were not synthesized because of heterogeneity and the limited number of ***:Yoga is valuable in improving negative moods in patients with breast *** also concluded five key mechanisms of yoga therapy in improving negative *** well-designed RCTs with large sample size and long-term follow-up are needed.

关键词： Breast cancer Yoga Meta-analysis Negative emotion

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Monitoring glaciers in the Chenab basin with SBAS InSAR technology

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Journal of Mountain Science 2022年第9期19卷 2622-2633页

作者： DING Yue-kai LIU Rui FAN Yi-fei ZHOU ling-xiang JI Qin ZHANG Hong xiao zuo-lin The Key Laboratory of GIS Application Research School of Geography and TourismChongqing Normal UniversityChongqing 401331China

The Chenab basin is located in northwest India and eastern *** in Chenab basin,as local freshwater resources,are very important to the regional ecological environment and *** the same time,SBAS InSAR can monitor the deformation of the ground for a long time,the monitoring accuracy can reach mm level,and can obtain the time series change of deformation,whcih provides a new idea and method for glacier *** this study,the deformation from SBAS InSAR was combined with glacial area data to study the glacial changes in Chenab ***-1 and Landsat series images were used to obtain the deformation and change in the area of glaciers by SBAS InSAR and the semi-automated *** results showed that glaciers in the Chenab basin retreated rapidly,especially in the past ten *** glacier area decreased by 88.05 km^(2)in 1990~2000 and 118.86 km^(2) in 2000~2010,and the glacier area decreased by 236.01 km^(2) in 2010~2020,which was the largest rate of change of 9.49%.Moreover,glacial deformation decreased in 2020,and the deformation rate ranged from-146.3mm/a to 119.52 mm/*** glaciers had deformation rates between-50 mm/a and 50 mm/*** by precipitation and temperature,glacial deformation in the Chenab basin started to change in August,the maximum accumulation was 6,828.43mm,and the minimum ablation was-20,656.41 mm.

关键词： Glacier retreat SBAS-InSAR Climate change Chenab basin

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Effectiveness of integrated nursing interventions for fatigue in patients with advanced cancer:a systematic review of randomized controlled trials

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Frontiers of Nursing 2019年第3期6卷 203-210页

作者： xiao-lin zuo Yan Wen Shang-Qun Gong Fan-Jie Meng Department of Nursing The Central Hospital of Luohe(the First Affiliated Hospital of Luohe Medical College)LuoheHenan 462000China Tianjin University of Traditional Chinese Medicine Tianjin 300193China

Objective:To evaluate the effectiveness of integrated nursing interventions for fatigue in patients with advanced ***:Medline,Pubmed,Embase,CINAHL,Web of Science,and the Cochrane Library were searched systematically till June 2017.A systematic review was conducted to collect randomized controlled trials(RCTs)reporting on the effect of nurse-driven interventions to improve fatigue in patients with advanced *** assessment was conducted using the Cochrane Collaboration’s risk of bias ***:Six RCTs involving 736 adult participants were *** fatigue intensity was improved significantly by nursing *** analyzed results revealed significant improvements in the intervention group:less than 3 months(standard mean difference[SMD]=?0.33,95%confidence interval[CI][?0.48,?0.19],P<0.01)and more than or equal to 3 months(SMD=?0.40,95%CI[?0.57,?0.24],P<0.01).Four studies with a moderate risk of bias were judged,and the remaining studies were at high risk of ***:The results indicate that integrated nursing interventions may relieve fatigue in patients with advanced ***,due to the high risk of bias in most of the included studies and the diversity of interventions,the results and implementation process should be carefully monitored.

关键词： fatigue neoplasms nurses palliative care advanced evidence-based nursing systematic review hospice and palliativecare nursing

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Characteristics and changes of the Himalayas glacial area in China during 1990-2015

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Journal of Mountain Science 2022年第7期19卷 1961-1973页

作者： SHI Shu-xian XING Li DING Yue-kai DONG Jun LIU Rui JI Qin xiao zuo-lin HUANG Xun The Key Laboratory of GIS Application Research School of Geography and TourismChongqing Normal UniversityChongqing401331China Key Laboratory of Geographic Information Science(Ministry of Education) East China Normal UniversityShanghai2002412China

In recent decades,the continuously changed glaciers in the Himalayas not only affected process of atmospheric flow and water cycle in the plateau but also increased the frequency of secondary disasters,such as ice collapse and outburst ***,the monitoring of Himalayas glacial change is of great significance in the aspects of climate change and disaster prevention and *** Himalayas glacier outlines in China were extracted by ratio threshold and visual interpretation based on the Landsat TM/ETM+/OLI data and glacier catalogue *** on the ASTER GDEM data,the distribution and change characteristics at different altitudes were studied,and the surface moraine was identified to study the influence of glacial area *** addition,Glaciers were divided into marine and continental glaciers in this study,and the distribution and changes of the two types of glaciers were ***,a comprehensive analysis of a long time series was *** results showed that:(1)From 1990 to 2015,the glaciers in the study area showed an overall trend of melting;the annual melting speed gradually accelerated from 0.48%/a to 0.75%/*** total melting glacial area was 828.16 km,and the melting rate of the glaciers in the western section was the highest,at 0.63%.(2)The total area of continental glaciers was larger than that of marine glaciers,and its reduction was relatively larger,too.(3)The average size of debris-covered glaciers was 10 times that of debris-free glaciers,but their rate of change(8.1%)was 1/2 of that of debrisfree glaciers(17.8%).(4)The number of glaciers gradually decreased as the size of glaciers *** glaciers with grades of>50 km,0.5~1 km,and 1~2 kmhad large change rates,which were 20.1%,19.1%,and 18.5%,*** summary,the Himalayas glaciers in China were melting at an accelerated rate and their numbers were gradually decreasing from 1990 to *** location,type,elevation,size and debris cover of a glacier are all i

关键词： Himalayas Glacial area Remote sensing Shrinkage and expansion area Debris-covered glaciers

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Systematic evaluation of the clinical nursing pathway with the GRADE approach applied to functional exercise in patients with hip replacements before and after surgery

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Chinese Nursing Research 2016年第4期3卷 185-193页

作者： lin Yang Xin-Man Wang xiao-lin zuo Shang-Qun Gong Fan-Jie Meng Tianjin University of Traditional Chinese Medicine Tianjin 300193China North AnHui Health Vocational College SuzhouAnhui 234000China

Objective： To evaluate the effect of the clinical nursing pathway applied to functional exercise in patients with hip replacements before and after the operation. Methods： The China National Knowledge Infrastructure （CNKI）, WanFang Data, Chinese science and technology journal database （VIP）, PubMed, Web of Science, EMBASE, CBM and the Cochrane Library （2015-5） were searched for randomized controlled trials （RCTs） on clinical nursing pathways for func- tional exercise in patients with hip replacements before and after surgery from June 2015 to January 2010. The references included in the literature were also retrieved. To meet the literature standard, 2 reviewers independently selected and extracted data according to the inclusion criteria and assessed the risks of bias. RevMan 5.3 software was used in this meta-analysis. The quality of evidence was evaluated using grade profiler3.6 software, the level recommended for grading. Results： A total of 15 RCTs and 1248 patients were included. The meta-analysis showed that, in the clinical nursing path group, the Harris score of hip function [SMD = 3.35, 95%CI （2.53, 4.16）, P 〈 0.00001 ] and incidence of thrombosis embolism [RR - 0.28, 95%0 （0.15, 0.53）, P 〈 0.0001 ], pulmonary infection [RR = 0.33, 95%CI （0.14, 0.82）, P = 0.02], urinary retention [RR - 0.22, 95%CI （0.09, 0.52）, P = 0.0005], constipation [RR = 0.20, 95%0 （0.10, 0.40）, P 〈 0.00001 ], patients＇ satisfaction for nursing care [RR -- 1.26, 95%0 （1.17, 1.36）, P 〈 0.00001 ] and shortened hospitalization times [5MD = -1.91, 95%C! （ 2.39, -1.43）, P 〈 0.0001 ]were statistically significantly better than those in the control group. However, in reducing joint dislocations [Rig = 0.25, 95%C1 （0.05, 1.15）, P - 0.08], pressure ulcers [RR = 0.25, 95%0 （0.03, 2.19）, P = 0.21], and incidence of complications [RR = 0.42, 95%0 （0.15, 1.12）, P = 0.08], there was no statis- tically significant difference between the two groups. Funnel plot analysis of the average length of stay

关键词： Hip replacementFunctional exerciseClinical nursing pathwayRandomized controlled trial (RCT)System evaluationGRADE approach

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重庆低山区SOCD空间格局变异特征及影响因子分析

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价值工程 2020年第31期39卷 230-232页

作者：肖作林重庆师范大学地理与旅游学院重庆401331

采用经典统计和地统计学相结合的方法研究低山区农耕地土壤有机碳空间分布特征及其与海拔、土壤类型、成土母质和种植制度之间的关系。结果表明,研究区20cm深度耕地土壤有机碳密度(SOCD)均值2.65kg/m2,低于全国平均水平(3.00kg/m2)。随... 详细信息

采用经典统计和地统计学相结合的方法研究低山区农耕地土壤有机碳空间分布特征及其与海拔、土壤类型、成土母质和种植制度之间的关系。结果表明,研究区20cm深度耕地土壤有机碳密度(SOCD)均值2.65kg/m2,低于全国平均水平(3.00kg/m2)。随着高程的增加,土壤有机碳密度呈增加趋势。各土壤类型土壤有机碳密度由大到小依次是石灰岩土>山地黄壤>冲积土>水稻土>紫色土。石灰岩风化物和白云岩风化物分布区更有利于土壤有机碳的积累。不同种植制度下土壤有机碳密度表现为:麦-玉-薯轮作>油-稻轮作>麦-玉轮作>玉米、水稻单一种植。土壤有机碳密度空间分布表现为带状各向异性,南北方向为主要变异方向。海拔、土壤类型、成土母质和种植制度共同决定了研究区耕地土壤有机碳的空间分布格局。

关键词：土壤有机碳密度地统计学各向异性

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Identification of a dual functional betulinic acid analog for the treatment of osteoarthritis by phenotypic screening

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Science China Life Sciences 2025年第1期 300-302页

作者： Ze-Min lin Mai Xiang Wen-Hui Wei Shu-Hui Fan Li Chen Jie Wang xiao-Qian Yang Chun-Hao Yang Shi-Jun He Jian-Ping zuo Laboratory of Immunopharmacology State Key Laboratory of Drug ResearchShanghai Institute of Materia MedicaChinese Academy of Sciences School of Pharmacy University of Chinese Academy of Sciences School of Pharmacy Nanjing University of Chinese Medicine State Key Laboratory of Drug Research Department of Medicinal ChemistryShanghai Institute of Materia MedicaChinese Academy of Sciences Innovation Research Institute of Traditional Chinese Medicine Shanghai University of Traditional Chinese Medicine Experiment Center for Science and Technology Shanghai University of Traditional Chinese Medicine

Dear Editor, Phenotypic drug discovery, which observes compound effects on physiology,has given way to targeting specific molecules, but has revived by using modern methods to find drugs based on therapeutic outcomes in disease models(Vincent et al., 2022). Osteoarthritis(OA) is a prevalent chronic joint disorder, primarily affecting knee joints, with osteoclast activation due to low-grade inflammation resulting in increased bone resorption and structural changes in the joint(Katz et al.,2021).

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Establishment of a modified high resolution melting assay based on allele-specific-extension to determine single nucleotide polymorphism

Establishment of a modified high resolution melting assay ba...

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中国神经科学学会第九届全国学术会议暨第五次会员代表大会

作者： Yan-Peng YUAN,Qing-ling lin,xiao-Hong zuo,Yan-Ning CAI Department of Neurobiology,Being Institute of Geriatric,Xuanwu Hospital,Capital Medical University,Beijing 100053,China

＜正＞Objective To establish a modified high resolution melting assay based on allele-specific-extension （ASE-HRM）to determine single nucleotide polymorphisms（SNP）.Methods The established ASE-HRM was designed as asymmetric polymerase chain reaction and melting curve *** allele-specific-extension（ASE） primer which ends at the SNP site and matches one of the allele was added to the reaction ***,asymmetric PCR Was performed with undergoing additional thermal steps in order to get allele-specific-extension.A total of 194 human genomic DNA samples were genotyped with the developed assay and by direct *** Heterozygotes could be discriminated from homozygotes according to their lower and broader melting *** different types of homozygote could be separated according to the presence or absence of an extension *** primers 11-13 bases long worked efficiently in an allele specific *** of the limiting amplification primer with locked nucleic acid increased the Tm difference between extension and amplification peaks and facilitated subsequent *** 194 human genomic DNA samples were genotyped with the developed assay and by direct sequencing,with the different methods providing identical genotyping *** ASE-HRM is a simple,inexpensive,closed-tube genotyping method that can be used to examine all types of SNP.

关键词： single nucleotide polymorphism high resolution melting curve analysis allele-specific-extension base-pair neutral variant

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