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Therapeutic effect and mechanism of breviscapine on cisplatin-induced nephrotoxicity in mice

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Asian Pacific Journal of Tropical Medicine 2015年第10期8卷 853-857页

作者： xiao-Yu Lou Jing-liang cheng Bo Zhang Department of Magnetic Resonance Imaging the First Affiliated Hospital of Zhengzhou University Department of Magnetic Resonance Imaging the First Affiliated Hospital of Luohe Medical College Department of Ultrasound in Medicine East HospitalTongji University School of Medicine

Objective:To observe the protective effect of breviscapineon mice with cisplatin-induced ***:Mice were given a single injection of cisplalin(8 mg/kg,up.);then,breviscapine was given to mice at 25 mg/kg and 50 mg/kg doses,respectively,once a day for seven *** tissue structure was observed after animals were *** urea nitrogen(BUN),serum creatinine(Scr),lipid peroxide(MDA) and superoxide dismutase(SOD) serum levels were detected;and MDA,glutathione peroxidase,and SOD levels in the renal cortex were ***:Compared with the blank control group(BCG),the kidney pathological damage of mice in the model control group(MCG) was more *** applying different doses of breviscapine,different degrees of renal injury improvement *** with the BCG,the serum levels of Scr and BUN in the MCG increased to(89.92±6.78) μmoL/L and(15.32±4.53) mmoL/*** differences were statistical significant(P<0.01).Compared with the MCG,the serum levels of Scr and BUN in the Bre low-dose groups and Bre high-dose groups decreased significantly(P<0.05).Compared with the BCG,the MDA levels in serum and in the renal cortex in the MCG significantly increased,while the SOD levels significantly *** the differences were statistically significant(P<0.01).In the Bre low-dose groups and Bre high-dose groups,MDA levels in serum and in the renal cortex significantly decreased,while SOD and glutathione peroxidase levels in the renal cortex significantly increased,compared with the MCG;and the differences were statistically significant(P<0.05).Conclusions:Breviscapine can reduce cisplatin induced renal toxicity in mice and it's possible through inhibition of renal tubule cell lipid peroxidation and reduces the nephrotoxicity of cisplatin.

关键词： Cisplatin Renal injury Breviscapine Protective eff

Equation based rate control scheme for video streaming over wireless channels with link level ARQ

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2006年第10期7卷 1702-1708页

作者： ZHU xiao-liang YANG Zong-kai DU Xu cheng Wen-qing Department of Electronics ＆ Information Engineering Huazhong University of Science ＆ Technology Wuhan 430074 China

Equation based TCP-friendly rate control (TFRC) protocol has been proposed to support video streaming applications. In order to improve TFRC performance in wireless channels, the link level automatic repeat request (ARQ) scheme is usually deployed. However, ARQ cannot ensure strict delay guarantees, especially over multihop links. This paper introduces a theoretical model to deduce an equation for packet size adjustment in transport layer to minimize retransmission delay by taking into con- sideration the causative reasons inducing retransmission in link layer. An enhanced TFRC (ETFRC) scheme is proposed inte- grating TFRC with variable packet size policy. Simulation results demonstrate that higher goodput, lower packet loss rate (PLR), lower frame transmission delay and jitter with good fairness can be achieved by our proposed mechanism.

关键词： TFRC Video streaming Wireless channels Automatic repeat request (ARQ) Rate control

Microstructure and properties after deformation and aging process of A286 superalloy

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Rare Metals 2019年第9期38卷 864-870页

作者： Si-cheng Liu Yun Gao Zhong-liang Lin Shuang-Shuang Guo xiao-Bin Zhang xiao-Jian Yin Research Institute of Aerospace Precision Products Co. Ltd

This study focuses on the effects of different cold-drawing deformations and aging treatments of solid solution A286 *** grain configuration,texture,precipitates and tensile strength of A286 superalloy after different deformations and aging treatments were investigated by optical microscopy(OM),field emission scanning electron microscopy(FESEM),electron back-scattered diffraction(EBSD)and mechanical testing *** grain size and configuration of A286 alloy can hardly be changed during aging *** initially equiaxial and twinned crystals are obvious when deformation is less than30%,while the grain boundaries become blurry and slip bands appear after 35% deformation or more.γ’ phase and Cr-rich carbide are the precipitates of A286 *** each deformation,γ’ phase plays a major role during aging and its amount increases gradually when the aging temperature changes from 650 to 680℃,and a maximum tensile strength appears when following two-stage *** deformation increasing,the amounts of γ’ phase and Crrich carbide increase in varying ***,thewire textures become more obvious,the tensile strength is enhanced and the kernel average misorientation(KAM)increases gradually;the higher KAM of crystal lattices diffuses from the grain boundary to the matrix gradually.

关键词： A286 alloy Deformation Aging Precipitate Texture Tensile strength

Reduced delay in diagnosis of odontogenic keratocysts with malignant transformation:A case report

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World Journal of Clinical Cases 2020年第11期8卷 2374-2379页

作者： xiao-Juan Luo Ming-liang cheng Chun-Ming Huang xiao-Ping Zhao Center of Stomatology Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030Hubei ProvinceChina

BACKGROUND In rare cases,odontogenic keratocysts(ODs)transform into squamous cell *** between the first attendance of a patient and the diagnosis of OD with malignant transformation vary from weeks to *** this article,we report a case of malignancy derived from OD with a five-day delay in *** SUMMARY A 54-year-old woman was referred to Tongji Hospital in Wuhan,China with complaints of moderate pain,recurrent swelling,and pus discharge around her left maxillary lateral incisor for over 10 *** examination revealed a fistula at the palatine-side mucoperiosteum of the left maxillary lateral incisor and enlarged lymph node in the left *** beam computed tomography revealed a cystic lesion with massive bone destruction from the left maxillary central incisor to the left secondary maxillary premolar and local bony destruction in the left first mandibular *** patient was clinically diagnosed with *** rather than marsupialization was performed given the risk factors of long history,recent aggravated pain,and massive bony *** transformation of OD was confirmed by pathologists 3 d after the *** surgery was performed,and lymph node metastasis was *** patient was subjected to postoperative radiotherapy and synchronous chemotherapy,and no local recurrence or distant metastasis was noted at one-year *** Our case suggests that clinicians should be aware of the malignant transformation of OD,especially when patients present with a long history,massive cyst,chronic inflammation,recent persistent infections,aggravated pain,numbness around the cystic lesion,and lymph node enlargement.

关键词： Odontogenic keratocysts Malignant transformation Primary intraosseous squamous cell carcinoma Delay in diagnosis Enucleation Case report

Element doping induced microstructural engineering enhancing the lithium storage performance of high-nickel layered cathodes

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Journal of Energy Chemistry 2023年第2期77卷 461-468,I0012页

作者： Zhizhan Li xiao Huang Jianing liang Jinlei Qin Rui Wang Jinguo cheng Deli Wang Key Laboratory of Material Chemistry for Energy Conversion and Storage(Huazhong University of Science and Technology) Ministry of EducationHubei Key Laboratory of Material Chemistry and Service FailureSchool of Chemistry and Chemical EngineeringHuazhong University of Science and TechnologyWuhan 430074HuibeiChina

The high-nickel layered cathodes Li[Ni_(x)Co_(y)Mn_(1-x-y)]O_(2)(x≥0.8)with high specific capacity and long cycle life are considered as prospective cathodes for lithium-ion ***,the microcrack formation and poor structural stability give rise to inferior rate performance and undesirable cycling ***,we propose a dual modification strategy combining primary particle structure design and element doping to modify Li[Ni_(0.95)Co_(0.025)Mn_(0.025)]O_(2) cathode by tungsten and fluorine co-doped(W-F-NCM95).The doping of W can convert the microstructure of primary particles to the unique rod-like shape,which is beneficial to enhance the reversibility of phase transition and alleviate the generation of microcracks.F doping is conducive to alleviating the surface side ***,due to the synergistic effect of W,F codoping,the obtained W-F-NCM95 cathodes deliver a high initial capacity of 236.1 mA h g^(-1) at 0.1 C and superior capacity retention of 88.7%over 100 cycles at 0.5 ***,the capacity still maintains73.8%after 500 cycles at 0.5 C and the texture of primary particle is *** work provides an available strategy by W and F co-doping to enhance the electrochemistry performance of high-nickel cathodes for practical application.

关键词： High-nickel cathodes Multi-strategy Cation-anion co-doping Particle structure design Synergistic effect

甲酸钙对水泥浆体抗压强度、水化及孔结构的影响

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安徽建筑工业学院学报（自然科学版） 2013年第6期21卷 54-58页

作者：孙道胜许炜王爱国梁晓晨朱曼丽安徽建筑大学先进建筑材料安徽省重点实验室安徽合肥230022

研究了甲酸钙对普通硅酸盐水泥浆体和硅酸盐水泥浆体抗压强度的影响,采用XRD、压汞法和灼烧法,测试了甲酸钙对水泥浆体水化产物组成、孔结构及化学结合水的影响。结果表明:甲酸钙能加速水泥的水化,促进Ca(OH)2的生成,提高水泥浆体的水... 详细信息

研究了甲酸钙对普通硅酸盐水泥浆体和硅酸盐水泥浆体抗压强度的影响,采用XRD、压汞法和灼烧法,测试了甲酸钙对水泥浆体水化产物组成、孔结构及化学结合水的影响。结果表明:甲酸钙能加速水泥的水化,促进Ca(OH)2的生成,提高水泥浆体的水化程度;甲酸钙能明显改善水泥浆体的孔结构,减少孔隙率和细化孔径;甲酸钙对P·O 42.5普通硅酸盐水泥浆体早期强度的提升要比对P·Ⅱ52.5硅酸盐水泥的效果好。

关键词：甲酸钙水泥浆体抗压强度化学结合水孔结构

PSO Optimal Control of Model-free Adaptive Control for PVC Polymerization Process

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International Journal of Automation and computing 2018年第4期15卷 482-491页

作者： Shu-Zhi Gao xiao-Feng Wu liang-liang Luan Jie-Sheng Wang Gui-cheng Wang School of Electronic and Information Engineering Shenyang University of Chemical Technology University of Science and Technology Liaoning National Financial Security and System Equipment Engineering Research Center

Polyvinyl chloride （PVC） polymerizing process is a typical complicated industrial process with the characteristics of large inertia, big time delay and nonlinearity. Firstly, for the general nonlinear and discrete time system, a design scheme of model-free adaptive （MFA） controller is given. Then, particle swarm optimization （PSO） algorithm is applied to optimizing and setting the key parameters for controller tuning. After that, the MFA controller is used to control the system of polymerizing temperature. Finally, simulation results are given to show that the MAC strategy based on PSO obtains a good controlling performance index.

关键词： Polyvinyl chloride(PVC) polymerization temperature model-free adaptive control particle swarm optimization(PSO)algorithm.

Identifying the dynamic behaviors in complete reconstruction of Co-based complex precatalysts during electrocatalytic oxygen evolution

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Journal of Energy Chemistry 2025年第1期100卷 226-233页

作者： Jingfang Zhang Danyang Wu Linke Cai Youluan Lu Fanpeng cheng Lijuan Shi Qun Yi Yao Liu Yi Huang Key Laboratory of Green Chemical Engineering Process of Ministry of Education Engineering Research Center of Phosphorus Resources Development and Utilization of Ministry of Education Hubei Key Laboratory of Novel Reactor and Green Chemical Technology School of Chemical Engineering & Pharmacy Wuhan Institute of Technology Key Laboratory of Pesticide & Chemical Biology of Ministry of Education Engineering Research Center of Photoenergy Utilization for Pollution Control and Carbon Reduction of Ministry of Education College of Chemistry Central China Normal University College of Materials Science and Engineering Fuzhou University

Transition metal-based nanomaterials have emerged as promising electrocatalysts for oxygen evolution reaction（OER）. Considerable research efforts have shown that self-reconstruction occurs on these nanomaterials under operating conditions of OER process. However, most of them undergo incomplete reconstruction with limited thickness of reconstruction layer, leading to low component utilization and arduous exploration of real catalytic mechanism. Herein, we identify the dynamic behaviors in complete reconstruction of Co-based complexes during OER. The hollow phytic acid（PA） cross-linked CoFe-based complex nanoboxes with porous nanowalls are designed because of their good electrolyte penetration and mass transport ability, in favor of the fast and complete reconstruction. A series of experiment characterizations demonstrate that the reconstruction process includes the fast substitution of PA by OH-to form Co（Fe）(OH)xand subsequent potential-driven oxidation to Co（Fe）OOH. The obtained CoFeOOH delivers a low overpotential of 290 mV at a current density of 10 mA cm-2and a long-term *** experiment results together with theory calculations reveal that the Fe incorporation can result in the electron rearrangement of reconstructed CoFeOOH and optimization of their electronic structure,accounting for the enhanced OER activity. The work provides new insights into complete reconstruction of metal-based complexes during OER and offers guidelines for rational design of high-performance electrocatalysts.

关键词： Complete reconstruction Co-based complex Precatalysts Oxygen evolution reaction

Radiomics and molecular analysis:Bridging the gap for predicting hepatocellular carcinoma prognosis

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World Journal of Clinical Cases 2025年第4期13卷 56-60页

作者： Chun-Han cheng Wen-Rui Hao Tzu-Hurng cheng Department of Medical Education Linkou Chang Gung Memorial HospitalTaoyuan 33305TaiwanChina Division of Cardiology Department of Internal MedicineShuang Ho HospitalMinistry of Health and WelfareTaipei Medical UniversityNew Taipei 23561TaiwanChina Division of Cardiology Department of Internal MedicineSchool of MedicineCollege of MedicineTaipei Medical UniversityTaipei 11002TaiwanChina Department of Biochemistry School of MedicineCollege of MedicineChina Medical UniversityTaichung 404333TaiwanChina

This editorial examines a recent study that used radiomics based on computed tomography(CT)to predict the expression of the fibroblast-related gene enhancer of zeste homolog 2(EZH2)and its correlation with the survival of patients with hepatocellular carcinoma(HCC).By integrating radiomics with molecular analysis,the study presented a strategy for accurately predicting the expression of EZH2 from CT *** findings demonstrated a strong link between the radiomics model,EZH2 expression,and patient *** noninvasive approach provides valuable insights into the therapeutic management of HCC.

关键词： Hepatocellular carcinoma Computed tomography Radiomics Enhancer of zeste homologue 2 expression Non-invasive imaging