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Brain-derived neurotrophic factor protects against acrylamide-induced neuronal and synaptic injury via the TrkB-MAPK-Erk1/2 pathway

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Neural Regeneration Research 2021年第1期16卷 150-157页

作者： xiao Chen Jing-Wei xiao Peng cao Yi Zhang Wen-jian Cai Jia-Yang Song Wei-Min Gao Bin Li Department of Toxicology Key Lab of Chemical Safety and HealthNational Institute of Occupational Health and Poison ControlChinese Center for Disease Control and PreventionBeijingChina Department of Occupational and Environmental Health Sciences School of Public HealthWest Virginia UniversityMorgantownWVUSA

Acrylamide has been shown to be ***-derived neurotrophic factor(BDNF)can alleviate acrylamide-induced synaptic injury;however,the underlying mechanism remains *** this study,dibutyryl-cyclic adenosine monophosphate-induced mature human neuroblastoma(NB-1)cells were exposed with 0–100μg/mL acrylamide for 24–72 *** decreased cell viability and destroyed *** of co-cultured NB-1 cells and Schwann cells to 0–100μg/mL acrylamide for 48 hours resulted in upregulated expression of synapsin I and BDNF,suggesting that Schwann cells can activate self-protection of *** co-culture conditions,activation of the downstream TrkB-MAPK-Erk1/2 pathway strengthened the protective *** BDNF can increase expression of TrkB,Erk1/2,and synapsin I,while exogenous BDNF or the TrkB inhibitor K252a could inhibit these *** together,Schwann cells may act through the BDNF-TrkB-MAPK-Erk1/2 signaling pathway,indicating that BDNF plays an important role in this ***,exogenous BDNF may be an effective treatment strategy for acrylamide-induced nerve *** study was approved by the Laboratory Animal Welfare and Ethics Committee of the National Institute of Occupational Health and Poison Control,a division of the Chinese Center for Disease Control and Prevention(approval ***-2017-008)on May 29,2017.

关键词： factor injury pathway peripheral nerve protection protein regeneration repair

Electrochemical Behavior of CoSb_3-based Electrodes Using Binary PAni/PVDF Binder

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Journal of Materials Science & Technology 2007年第1期23卷 142-144页

作者： jian XIE Xinbing ZHAO Gaoshao cao Department of Materials Science and Engineering Zhejiang University Hangzhou 310027 China

The polyaniline （PAni）/polyvinylidene fluoride （PVDF） hybrid was served as a novel binder for CoSb3-based alloy electrode. The effect of PAni content on the electrochemical performances of the alloy electrode was investigated. It was found that the CoSb3 electrode using the binary PAni/PVDF binder exhibits higher reversible capacity than that using the single PVDF binder, especially in the initial cycles. As a result, the PAni/PVDF hybrid could be a promising binder for the alloy electrode.

关键词： PAni/PVDF binder CoSb3 electrode Electrochemical behavior Lithium ion batteries

SAR image denoising based on wavelet-fractal analysis

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Journal of Systems Engineering and Electronics 2007年第1期18卷 45-48页

作者： Zhao jian cao Zhengwen Zhou Mingquan School of Electronics and Information Northwestern Polytechnical Univ. Xi'an 710072 E R. China School of Information Science and Technology Northwest Univ. Xi'an 710069 E R. China

Wavelet-fractal based SAR （synthetic aperture radar） image processing is one of the advanced technologies in image processing. The main concept of analysis is that after wavelet transformation, multifractal spectrum of the signal is different from that of noise. This difference is used to alleviate the noise produced by SAR *** method to denoise SAR image using the process based on wavelet-fractai analysis is discussed in detail. Essentially, the present method focuses on adjusting the Hoelder exponent α of multifractal spectrum. After simulation, α should be adjusted to 1.72-1.73. The more the value of α exceeds 1.73, the less distinctive the edges of SAR image become. According to the authors denoising is optimal at α=1.72-1.73. In other words, when α =1.72-1.73, a smooth and denoised SAR image is produced.

关键词： Synthetic aperture radar image Wavelet Multifractal analysis Denoising Hoelder exponent

Hydrogen-bonded organic framework core–shell composite for synergistic antimicrobial therapy

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Aggregate 2024年第2期5卷 457-462页

作者： jian xiao Acharya Ramachandra Mahammed Shaheer Chen Liu Tian-Fu Liu Rong cao State Key Laboratory of Structural Chemistry Fujian Institute of Research on the Structure of MatterChinese Academy of SciencesFuzhouChina School of Physical Science and Technology ShanghaiTech UniversityShanghaiChina University of Chinese Academy of Sciences BeijingChina

Hydrogen-bonded organic frameworks(HOFs)are crystalline porous materials with permanent voids formed via self-assembly of organic molecules through hydrogen bonding and intermolecular *** combination of HOFs with functional material would broaden their application horizon but were less explored in existing ***,a highly porous and photosensitive HOF was successfully coated onto upconversion nanoparticles(UCNPs)to construct a core-shell structure named UNCPs@*** enhance spectral overlap and maximize energy conversion efficiency,this study utilized the Er and Tm co-doped UCNPs,which can effectively convert infrared light into visible light emission thereby exciting the porphyrin *** investigation reveals that the composite exhibits significant photodynamic and photothermal effects under infrared *** by its noticeable photoactivity,UCNPs@PFC-73-Ni was evaluated as an antibacterial agent against Escherichia ***,significant antibacterial efficacy was observed,highlighting the potential of UCNPs@PFC-73-Ni as an effective antibacterial agent under infrared light irradiation.

关键词： hydrogen-bonded organic frameworks photodynamic therapy photothermal therapy upconversion nanoparticles

Effects of source facies and maturity on individual carbon isotopic compositions of oil

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Geoscience Frontiers 2024年第5期15卷 210-221页

作者： Jingkun Zhang jian cao Baoli Xiang State Key Laboratory of Palaeobiology and Stratigraphy Nanjing Institute of Geology and PalaeontologyChinese Academy of SciencesNanjing 210008China MOE Key Laboratory of Surficial Geochemistry School of Earth Sciences and EngineeringNanjing UniversityNanjing 210023China Research Institute of Experiment and Testing PetroChina Xinjiang Oilfield CompanyKaramayXinjiang 834000China

Carbon isotopes have been used extensively in tracing the sources of ***,primary source facies and secondary alteration controls on oil isotopic compositions have not been well resolved,resulting in application uncertainties.A case study was undertaken for an alkaline lacustrine oil system in a lower Permian formation in the Junggar Basin,NW *** indicate that increasing maturity causes the carbon isotopic composition to become heavier for only short–middle-chain compounds,whereas source facies-related carbon assimilation controls the compositions of short-,middle-,and long-chain *** particular,light-carbon assimilation during organic-matter degradation makes the isotopic composition lighter,whereas heavy carbon from the water mass makes it ***,oils in this study area were divided into Type U and Type N oils based on individual compound carbon isotopic compositions,reflecting the difference in source facies in a highly saline and reducing stratified water *** results provide a better understanding of the controls on carbon isotopes in oil in sedimentary basins,reducing the uncertainty in oil–source correlation and addressing the origin of oil.

关键词： Carbon assimilation Water stratification Carbon isotopes Alkaline lacustrine Junggar Basin

A Thermo-Tunable Metamaterial as an Actively Controlled Broadband Absorber

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Engineering 2023年第1期20卷 143-152页

作者： xiao-Chang Xing Yang cao xiao-Yong Tian Lingling Wu State Key Laboratory for Manufacturing Systems Engineering Xi’an Jiaotong UniversityXi’an 710049China

Metamaterials have attracted increasing attention in recent years due to their powerful abilities in manipulating electromagnetic (EM) waves. However, most previously reported metamaterials are unable to actively control full-band EM waves. In this paper, we propose a thermo-tunable broadband metamaterial (T-TBM) using paraffin-based composites (PD-Cs) with different phase transition temperatures. Active control of the T-TBM reflection loss peaks from low to high frequency is realized by manipulating the solid–liquid state of the PD-Cs at different phase transition temperatures. The absorption peak bandwidth (where the reflection loss value is less than −30 dB) can be changed, while the broad bandwidth absorption (where the reflection loss value is less than −10 dB) is satisfied by adjusting the temperature of the T-TBM. It is shown that the stagnation of the phase transition temperature of the PD-Cs in the T-TBM provides a time window for actively controlling the EM wave absorption response under different thermal conditions. The device has a broad application prospect in the fields of EM absorption, intelligent metamaterials, multifunctional structural devices, and more.

关键词： Metamaterials Active control Thermally tunable Br oadband absorption

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Finite NPDM-groups

Acta Mathematica Sinica,English Series 2021年第2期37卷 306-314页

作者： jian Ji cao Xiu Yun GUO School of Applied Mathematics Shanxi University of Finance and EconomicsTaiyuan 030006P.R.China Department of Mathematics Shanghai UniversityShanghai 200444P.R.China

In this paper the classification is given for finite groups in which the normalizer of every non-normal cyclic subgroup of order divided by the minimal prime of |G| is a maximal subgroup.

关键词： Normalizer cyclic subgroup maximal subgroup

Direct numerical simulation of shock wave/boundary layer interaction controlled by steady microjet in a compression ramp

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Chinese Journal of Aeronautics 2024年第10期37卷 83-102页

作者： Ruoye xiao Dong SUN jian YU School of Aeronautic Science and Engineering Beihang UniversityBeijing 100191China State Key Laboratory of Aerodynamics Mianyang 621000China

Shock wave/boundary layer interaction in a 24°turning angle of the compression ramp at Mach number 2.9 controlled by steady microjet is investigated using direct numerical *** different jet spacings which are termed as sparse,moderate and dense are considered,and the induced vortex system and shock structures are compared.A moderate jet spacing configuration is found to generate counter-rotating vortex pairs that transport high-momentum fluid towards the vicinity of wall and strengthen the boundary layer to resist separation,reducing the separation *** dense jet spacing configuration creates a larger momentum deficit region,reducing the friction downstream of the *** of pressure and pressure gradient reveals that dense jet spacing configuration reduces the intensity of separation *** impact of varying jet spacings on the turbulent kinetic energy transport mechanism is also investigated by decomposing the budget terms in the transport ***,the spectral characteristics of the separation region are studied using power spectral density and dynamic mode decomposition methods,revealing that moderate jet spacing configuration suppresses low-frequency fluctuations in the separation region.

关键词： Shock wave/boundary layer interaction Compression ramp Steady microjet Different jet spacings Direct numerical simulation

Brill-Noether Theory for Rank Two Vector Bundles Generated by Their Sections

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Acta Mathematica Sinica,English Series 2008年第12期24卷 1995-2010页

作者： jian Do xiao xiao jiang TAN School of Mathematical Sciences Peking University Beijing 100871 P. R. China School of Mathematics Southwest Jiaotong University Chengdu 611756 P. R. China LMAM and School of Mathematical Sciences Peking University Beijing 100871 P. R. China

We here study the Brill-Noether theory for rank two vector bundles generated by their sections. We generalize the vanishing theorem, the Clifford theorem and the existence theorem to such bundles.

关键词： rank two vector bundle vanishing theorem Clifford theorem existence theorem