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Metabolic syndrome in patients with atrial fibrillation in the absence of structural heart disease from a tertiary hospital in China

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Chinese Medical Journal 2009年第22期122卷 2744-2747页

作者： TANG Ri-bo GAO Ling-yun DONG Jian-zeng liu xiao-hui liu Xing-peng WU Jia-hui LONG De-yong YU Rong-hui DU Xin MA Chang-sheng Department of Cardiology Beijing Anzhen Hospital Capital Medical University Beijing 100029 China

Background Metabolic syndrome （MetS） and atrial fibrillation （AF） are causally related. This study aimed to determine the prevalence of MetS in patients with AF in the absence of structural heart disease from a tertiary hospital in China. Methods In a single center, 741 inpatients with AF in the absence of structural heart disease prior to catheter ablation were retrospectively reviewed. Among them, 588 （79.4%） patients had paroxysmal AF. Subgroup analyses were performed in paroxysmal AF and persistent/permanent AF.Results MetS was found in 343 （46.3%） patients （200 males, 143 females）; 0, 1, 2, 3, 4, 5 components of the MetS were found in 59 （8.0%）, 140 （18.9%）, 199 （26.9%）, 203 （27.4%）, 103 （13.9%） and 37 （5.0%） patients, respectively. The prevalences of overweight/obesity, high blood pressure, high glucose level, high triglyceride level and low high density lipoproteins cholesterol level were 53.8%, 47.6%, 23.2%, 40.6% and 72.1%, respectively. The prevalence of MetS was not significantly different between the paroxysmal AF group and the persistent/permanent AF group （44.6% vs 52.9%, P=0.064）. The five components of MetS except overweight/obesity （69.3% vs 49.8%, P 〈0.001） were not significantly different between the aforementioned two groups. The left atrium diameter increased with the sum of the MetS components. The left atrium diameter in the MetS group was significantly higher than that in the non-MetS group both in patients with paroxysmal AF and in patients with persistent/permanent AF.Conclusions The prevalence of MetS in patients with AF prior to catheter ablation is high. Further study and prevention are needed.

关键词： metabolic syndrome atrial fibrillation catheter ablation

SYNTHESIS OF A KETAL BY USING HPA AS CATALYST

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Chinese Chemical Letters 1994年第10期5卷 821-,222页

作者： Wan Sheng YOU Yuan Peng GU xiao hui liu Xing TIAN (Department of Chemisty, Liaoning Normal University, Dalian, 116022)

The work herein reported is about a rapid and convenient synthetic method of a betal formed from ethylene glycol and cyclohexanone by using H3PW12O40(HPA)as catalyst. It has ben shown that the reaction, by using HPA as catalyst, can proceed at room temperature and have the high yield of 92% and the catalyst can be used again and again

关键词： HPA AS SYNTHESIS OF A KETAL BY USING HPA AS CATALYST

Modeling the Flexural Carrying Capacity of Corroded RC Beam

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Journal of Shanghai Jiaotong university(Science) 2008年第2期13卷 129-135页

作者：王小惠刘西拉 Department of Civil Engineering Shanghai Jiaotong University

Considering the change of bond strength between corroded steel and concrete,flexural carrying ca- pacity of corroded reinforced concrete (RC) beam was *** the basis of the condition of equilibrium of forces and compatibility of deformations for the whole beam,a model for the prediction of flexural carrying capacity of the corroded RC beam was *** of the model's predictions with the experimental results published in the literature shows the practicality of the proposed method.

关键词： bond strength flexural capacity mechanical behavior corroded reinforced concrete beam

Recent advances in nickel-based catalysts for electrochemical reduction of carbon dioxide

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Advanced Sensor and Energy Materials

Advanced Sensor and Energy Materials 2023年第3期2卷 47-67页

作者： xiao-hui liu xiao-Long Jia Ya-Ling Zhao Rui-Xue Zheng Qing-Lei Meng Chang-Peng liu Wei Xing Mei-Ling xiao State Key Laboratory of Electroanalytical Chemistry Changchun Institute of Applied ChemistryChinese Academy of SciencesChangchun 130022China School of Applied Chemistry and Engineering University of Science and Technology of ChinaHefei 230026China Laboratory of Advanced Power Sources Changchun Institute of Applied ChemistryChinese Academy of SciencesChangchun 130022China

The carbon dioxide electroreduction reaction(CO_(2)RR)represents a sustainable way to store intermittent renewable energy in a manner that generates virtually zero net emissions,yet the energy efficiency remains a significant bottleneck due to its sluggish kinetics and complex reaction *** is a strong demand for highly efficient electrocatalysts that can achieve high energy and Faradaic efficiency,as well as rapid *** various developed CO_(2)RR catalysts,nickel-based materials have garnered increasing attention due to their outstanding performance and low *** this review,the relevant CO_(2)RR mechanisms are firstly discussed in *** this,several typical Ni-based catalysts including Ni-based complexes catalysts,nanoparticles and alloys,Ni-based compounds,and atomically dispersed Ni catalysts are *** preparation strategies for industrial level electrocatalysts are also highlighted in this ***,the opportunities,challenges and future outlooks of CO_(2)RR technology are *** review introduces the recent advances and frontiers of nickel-based CO_(2)RR catalysts,which enlightens the path for further exploration of highly efficient CO_(2)RR electrocatalysts.

关键词： nickel dioxide summarized

Rapamycin and 3-methyladenine regulate apoptosis and autophagy in bone-derived endothelial progenitor cells

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Chinese Medical Journal 2012年第22期125卷 4076-4082页

作者： LEI Feng-rui LI xiao-qiang liu hui ZttU Ren-da MENG Qing-you RONG Jian-jie Soochow Univ Dept Vasc Surg Affiliated Hosp 2 Suzhou 215004 Jiangsu Peoples R China First Peoples Hosp Wuxi Dept Gengral Surg Wuxi 214002 Jiangsu Peoples R China Peoples Hosp Haining Dept Gengral Surg Haining 314400 Zhejiang Peoples R China

Background Mammalian target of rapamycin （mTOR） is involved in a caspase independent form of programmed cell death called autophagy. The aim of this research was to investigate the effects of rapamycin and 3-methyladenine （3-MA） on autophagy, proliferation, apoptosis, and cell-cycle parameters of rat bone marrow-derived endothelial progenitor cells （EPCs）. Methods Mononuclear cells isolated from rat bone marrow were treated with rapamycin （0.01, 0.1, 1, or 10 pg/L） or 3-MA （1.25, 2.5, 5, or 10 mmol/L） for 24 hours. Expression of the autophagy marker protein LC3-11 was analyzed by Western blotting. Apoptosis and cell-cycle progression were analyzed by flow cytometry. Cell proliferation was measured using the MTT assay. Results Rapamycin treatment of EPCs induced apoptosis and autophagy and inhibited proliferation and cell-cycle progression in a dose-dependent manner. Treatment with 5 mmol/L 3-MA promoted cell proliferation; in contrast, treatment with 10 mmol/L 3-MA promoted apoptosis and induced S-phase arrest. Conclusions Rapamycin treatment of EPCs induced apoptosis and autophagy. Low concentrations of 3-MA had no significant effect on the proliferation and apoptosis of EPCs; The 5 mmol/L group promoted cell proliferation, but had no effect on the apoptosis; the 10 mmol/L group inhibited the proliferation and promoted apoptosis through the cell cycle.

关键词： apoptosis autophagy endothelialprogenitor cells rapamycin 3-methyladenine

Syntheses of Tripod-Ligands-Based MOFs for Electrocatalytic Water Splitting

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Syntheses of Tripod-Ligands-Based MOFs for Electrocatalytic ...

MicroPath-A pathway-based pipeline for the comparison of multiple gene expression profiles to identify common biological signatures

河南省化学会2018年学术年会

作者： xiao-hui liu Zhen Jin Di-ming Chen Chun-shen liu Department of Material and Chemical Engineering Zhengzhou University of Light Industry

Metal–Organic Frameworks(MOFs)is an organic–inorganic hybrid crystalline material composed of organic ligands and inorganic metal *** a new kind of porous crystalline materials,MOFs display well–defined molecular structure and adjustable functional *** gas storage,heterogeneous catalysis and drug transport and other fields show good application *** main work of this thesis is to design and synthesize porous MOFs materials and apply them to the study of electrocatalytic dehydrogenation and oxygen *** specific research contents are as follows:using tripod ligand NTB NTB–3F and Co(NO)6HO CuCl 2HO under different solvent conditions(DMA CHCN mixed solvent and DMF CHCN and HO mixed solvent),two cases of porous MOFs material Co–NTB and Cu–NTB–3F were designed and synthesized by hydrothermal *** samples were characterized by X–ray powder diffraction(XRD),Infrared Spectroscopy(IR),UV–Vis–IR,fluorescence spectrum(FL)and thermogravimetric analysis(TG).To explore its electrocatalytic hydrogen release,oxygen release performance.

关键词： metal–organic framework electrocatalysis water splitting solvothermal reaction

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Journal of Biomedical Science and Engineering 2009年第2期2卷 106-116页

作者： Mohsin Khan Chandrasekhar Babu Gorle Ping Wang xiao-hui liu Su-Ling Li Immunology Group Institute of Cell and Molecular Sciences Barts and London School of Medicine London UK. Intelligent Data Analysis Group Department of Information Systems and Computing Molecular Immunology & bioinformatics Group Microarray Facility Division of Bio-Sciences Brunel University Uxbridge UB8 3PH UK

High throughput gene expression analysis is swiftly becoming the focal point for deciphering molecular mechanisms underlying various dif-ferent biological questions. Testament to this is the fact that vast volumes of expression profiles are being generated rapidly by scientists worldwide and subsequently stored in publicly available data repositories such as ArrayEx-press and the Gene Expression Omnibus (GEO). Such wealth of biological data has motivated biologists to compare expression profiles gen-erated from biologically-related microarray ex-periments in order to unravel biological mecha-nisms underlying various states of diseases. However, without the availability of appropriate software and tools, they are compelled to use manual or labour-intensive methods of com-parisons. A scrutiny of current literature makes it apparent that there is a soaring need for such bioinformatics tools that cater for the multiple analyses of expression profiles. In order to contribute towards this need, we have developed an efficient software pipeline for the analysis of multiple gene expression data-sets, called Micropath, which implements three principal functions;1) it searches for common genes amongst n number of datasets using a number crunching method of comparison as well as applying the principle of permutations and combinations in the form of a search strat-egy, 2) it extracts gene expression patterns both graphically and statistically, and 3) it streams co-expressed genes to all molecular pathways belonging to KEGG in a live fashion. We sub-jected MicroPath to several expression datasets generated from our tolerance-related in-house microarray experiments as well as published data and identified a set of 31 candidate genes that were found to be co-expressed across all interesting datasets. Pathway analysis revealed their putative roles in regulating immune toler-ance. MicroPath is freely available to download from: ***/micropath.

关键词： Co-Expression Analysis Microarray Permutations and Combinations Multiple Gene Expression Analysis

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偏态自适型投影深度

数学学报（中文版） 2015年第3期58卷 507-520页

作者：刘小惠罗世华江西财经大学统计学院南昌330013 江西财经大学应用统计研究中心南昌330013

对常规投影深度进行了改进,得到了一类新的可自适应反映多元数据云偏态的统计投影深度.新的深度函数仍然具有凸的深度域,满足一般统计深度函数所应具备的全部基本特点.此外,还考虑了新投影深度函数的计算问题,证得在任意维空间里,它及... 详细信息

对常规投影深度进行了改进,得到了一类新的可自适应反映多元数据云偏态的统计投影深度.新的深度函数仍然具有凸的深度域,满足一般统计深度函数所应具备的全部基本特点.此外,还考虑了新投影深度函数的计算问题,证得在任意维空间里,它及由它诱导的深度域均是可以精确计算的,从技术角度讲,其处理比常规投影深度更加简便.最后,提供了一些数据示例用以展示此偏态自适型投影深度的有限样本性质.

关键词：偏态自适型投影深度深度域有偏数据

Sentiment Analysis Across Languages Based on Domain-Specific Emotional Dictionary

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Sentiment Analysis Across Languages Based on Domain-Specific...