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Calculation of the energy dependence of fission fragments yields and kinetic energy distributions for neutron-induced ^(235)U fission

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Chinese Physics C 2024年第8期48卷 159-169页

作者： Ya-Ning Han Zheng Wei Yi-Xuan Wang dong-Ying Huo Peng-Qi Zhang Ming Li Jun Ma Kang Wu Yong-Guang Zheng Yuan He Zhi-Yong Deng Tian-Zhi Jiang Xiang-Lin Zhuo Jin Li Yun Zhang Yu Zhang Jun-Run Wang xiao-dong su Ze-En Yao School of Nuclear Science and Technology Lanzhou UniversityLanzhou 730000China Engineering Research Center for Neutron Application Technology Ministry of EducationLanzhou UniversityLanzhou 730000China MOE Frontiers Science Center for Rare Isotopes Lanzhou UniversityLanzhou 730000China School of Mathematics and Statistics Lanzhou UniversityLanzhou 730000China Nuclear Power Institute of China Chengdu 610000China

Fission fragments yields and average total kinetic energy are fundamental nuclear data for nuclear energy applications and the study of nuclear *** fission products,such as ^(95)Zr,^(99)Mo,^(140)Ba,^(144)Ce,and ^(147)Nd,serve as burnup monitors,assessing the number of fissions induced by neutrons on ^(235)***,current experimental data for these fission products worldwide are inconsistent,introducing significant uncertainty into related scientific *** this study,we employed the Potential-driving Model to calculate the independent yields of ^(235)U and evaluate its advantages in such ***,we investigated the energy dependence of independent yields to select important ***,we calculated the cumulative yields of ^(95)Zr,^(99)Mo,^(140)Ba,^(144)Ce,and ^(147)Nd,and compared them with existing literature data to explore the energy dependence of fission products for ^(235)*** the lack of fission product yield data above 14.8 MeV,we extended our calculated incident neutron energy to 20 MeV,aiming to support future scientific *** Geant4 physical model does not consider the influence of incident neutron energy on the average total kinetic energy of fission fragments;thus,we introduced the excitation function of the total kinetic energy of fission fragments recommended by Madland et al.,which effectively describes the experimental data of the average total kinetic energy of fragments formed in ^(235)U *** this paper,we comprehensively discuss the energy dependence of fission product yields and average total kinetic energy.

关键词： ^(235)U(n f) potential-driving model fission yields kinetic energies energy dependence

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Transcriptome analyses of insect cells to facilitate baculovirus-insect expression

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Protein & Cell 2016年第5期7卷 373-382页

作者： Kai Yu Yang Yu xiaoyan Tang Huimin Chen Junyu xiao xiao-dong su Biodynamic Optical Imaging Center School of Life Science Peking University Beijing 100871 China State Key Laboratory of Protein and Plant Gene Research Peking University Beijing 100871 China Peking-Tsinghua Center for Life Sciences Peking University Beijing 100871 China

The High Five cell line （BTI-TN-5B1-4） isolated from the cabbage looper, Trichoplusia ni is an insect cell line widely used for baculovirus-mediated recombinant protein expression. Despite its widespread application in industry and academic laboratories, the genomic background of this cell line remains unclear. Here we sequenced the transcriptome of High Five cells and assembled 25,234 transcripts. Codon usage analysis showed that High Five cells have a robust codon usage capacity and therefore suit for expressing proteins of both eukaryotic- and prokaryotic-origin. Genes involved in glycosylation were profiled in our study, providing guidance for engineering glycosylated proteins in the insect cells. We also predicted signal peptides for transcripts with high expression abundance in both High Five and Sf21 cell lines, and these results have important implications for optimizing the expression level of some secretory and membrane proteins.

关键词： High Five cell line baculovirus-insect cellsystem codon usage glycosylation signal peptide

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Crystal structures of N-terminal WRKY transcription factors and DNA complexes

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Protein & Cell 2020年第3期11卷 208-213页

作者： Yong-ping Xu Hua Xu Bo Wang xiao-dong su State Key Laboratory of Protein and Plant Gene Research and Biomedical Pioneering Innovation Center(BIOPIC)Peking UniversityBeijing 100871China

Dear Editor,Plant-specific WRKY transcription factors(TFs)are among the largest families of TFs in higher plants;they are also found in the unicellular eukaryote Giardia lamblia and the slime mold Dictyostelium discoideum(Ulker and Somssich,2004),but not in *** TFs participate in diverse developmental and physiological processes in plants,such as disease resistance,abiotic stress responses,senescence,seed and trichome development,as well as additional developmental and hormone-controlled processes(Agarwal et al.,2011).

关键词： complexes families Crystal

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ABCG2-overexpressing S1-M1-80 cell xenografts in nude mice keep original biochemistry and cell biological properties

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Chinese Journal of Cancer 2012年第3期31卷 150-158页

作者： Fang Wang Yong-Ju Liang Xing-Ping Wu xiao-dong su Li-Wu Fu State Key Laboratory of Oncology in South China Sun Yat-sen University Cancer CenterGuangzhouGuangdong 510060P.R.China

S1-M1-80 cells,derived from human colon carcinoma S1 cells,are mitoxantrone-selected ABCG2-overexpressing cells and are widely used in in vitro studies of multidrug resistance(MDR).In this study,S1-M1-80 cell xenografts were established to investigate whether the MDR phenotype and cell biological properties were maintained in *** results showed that the proliferation,cell cycle,and ABCG2 expression level in S1-M1-80 cells were similar to those in cells isolated from S1-M1-80 cell xenografts(named xS1-M1-80 cells).Consistently,xS1-M1-80 cells exhibited high levels of resistance to ABCG2 substrates such as mitoxantrone and topotecan,but remained sensitive to the non-ABCG2 substrate ***,the specific ABCG2 inhibitor Ko143 potently sensitized xS1-M1-80 cells to mitoxantrone and *** results suggest that S1-M1-80 cell xenografts in nude mice retain their original cytological characteristics at 9 ***,this model could serve as a good system for further investigation of ABCG2-mediated MDR.

关键词：细胞生物学特性细胞移植生物化学裸鼠米托蒽醌多药耐药细胞学特征细胞周期

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Improving the UV-light stability of silicon heterojunction solar cells through plasmon-enhanced luminescence downshifting of YVO_(4):Eu^(3+),Bi^(3+)nanophosphors decorated with Ag nanoparticles

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Journal of Energy Chemistry 2023年第6期81卷 212-220,I0007页

作者： Cheng-Kun Wu Shuai Zou Chen-Wei Peng Si-Wei Gu Meng-Fei Ni Yu-Lian Zeng Hua sun xiao-Hong Zhang xiao-dong su School of Physical Science and Technology and Jiangsu Key Laboratory of Thin FilmsSoochow UniversitySuzhou 215006JiangsuChina Institute of Functional Nano&Soft Materials(FUNSOM) Soochow UniversitySuzhou 215123JiangsuChina

The ultraviolet(UV)light stability of silicon heterojunction(SHJ)solar cells should be addressed before large-scale production and *** downshifting(DS)nanophosphors on top of solar cells that can convert UV light to visible light may reduce UV-induced degradation(UVID)without sacrificing the power conversion efficiency(PCE).Herein,a novel composite DS nanomaterial composed of YVO_(4):Eu^(3+),Bi^(3+)nanoparticles(NPs)and AgNPs was synthesized and introduced onto the incident light side of industrial SHJ solar cells to achieve UV *** YVO_(4):Eu^(3+),Bi^(3+)NPs and Ag NPs were synthesized via a sol-gel method and a wet chemical reduction method,***,a composite structure of the YVO_(4):Eu^(3+),Bi^(3+)NPs decorated with Ag NPs was synthesized by an ultrasonic *** emission intensities of the YVO_(4):Eu^(3+),Bi^(3+)nanophosphors were significantly enhanced upon decoration with an appropriate amount of~20 nm Ag NPs due to the localized surface plasmon resonance(LSPR)*** the introduction of LSPR-enhanced downshifting,the SHJ solar cells exhibited an~0.54%relative decrease in PCE degradation under UV irradiation with a cumulative dose of 45 k W h compared to their counterparts,suggesting excellent potential for application in UV-light stability enhancement of solar cells or modules.

关键词： Downshifting Silver nanoparticles Localized surface plasmon resonance UV-light stability Silicon heterojunction solar cells

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Research on the Dynamic Compressibility of Polyurethane Microcellular Elastomer and its Application for Impact Resistance

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Chinese Journal of Polymer Science 2024年第8期42卷 1185-1197页

作者： Zhi-Ying Zhao Hao Jiang xiao-dong Li Xu-dong Zhang Xing su Mei-Shuai Zou School of Materials Science and Engineering Beijing Institute of TechnologyBeijing 100081China

The packaging materials with cushioning performance are used to prevent the internal contents from being damaged by the impact and vibration of external *** polyurethane microcellular elastomers(PUMEs)can absorb energy through cell collapse and molecular chain *** this study,PUMEs with different densities were investigated by scanning electron microscopy,dynamic mechanical analysis and dynamic compression *** exhibited significant im pact resistance and the maximum peak stress attenuation ratio reached 73.33%.The protective equipment was made by PUME with the optimal density of 600 kg/m^(3),and then the acceleration sensing device installed with the same protective equipment fell from a height of 3,5 and 10 m to evaluate the energy-absorbing property and reusability of *** results showed that PUMEs equipment reduced the peak acceleration of the device by 93.84%,with a maximum deviation of 9%between actual test and simulation,and shortened the impact time of first landing by 57.39%.In addition,the equipment PUMEs equipment could effectively reduce the stress on the protected items.

关键词： Polyurethane microcellular elastomer Impact velocity Stress attenuation ratio Impact resistance

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Arabidopsis transcription factor TCP4 represses chlorophyll biosynthesis to prevent petal greening

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Plant Communications 2022年第4期3卷 124-136页

作者： Xinhui Zheng Jingqiu Lan Hao Yu Jingzhe Zhang Yi Zhang Yongmei Qin xiao-dong su Genji Qin State Key Laboratory of Protein and Plant Gene Research School of Life SciencesPeking UniversityBeijing 100871People’s Republic of China

Green petals pose a challenge for pollinators to distinguish flowers from leaves,but they are valuable as a specialty flower ***,little is understood about the molecular mechanisms that underlie the development of green ***,we report that CINCINNATA(CIN)-like TEOSINTE BRANCHED 1/CYCLOIDEA/PCF(TCP)proteins play key roles in the control of petal *** septuple tcp2/3/4/5/10/13/17 mutant produced flowers with green petals due to chlorophyll *** of TCP4 complemented the petal phenotype of tcp2/3/4/5/10/13/*** found that chloroplasts were converted into leucoplasts in the distal parts of wild-type petals but not in the proximal parts during flower development,whereas plastid conversion was compromised in the distal parts of tcp2/3/4/5/10/13/17 ***4 and most CIN-like TCPs were predominantly expressed in distal petal regions,consistent with the green–white pattern in wild-type petals and the petal greening observed in the distal parts of tcp2/3/4/5/10/13/17 ***-sequencing data revealed that most chlorophyll biosynthesis genes were downregulated in the white distal parts of wild-type petals,but these genes had elevated expression in the distal green parts of tcp2/3/4/5/10/13/17 petals and the green proximal parts of wild-type *** revealed that TCP4 repressed chlorophyll biosynthesis by directly binding to the promoters of PROTOCHLOROPHYLLIDE REDUCTASE(PORB),DIVINYL REDUCTASE(DVR),and suPPRESSOR OF OVEREXPRESSION OF CO 1(SOC1),which are known to promote petal *** found that the conversion of chloroplasts to leucoplasts and the green coloration in the proximal parts of petals appeared to be conserved among plant *** findings uncover a major molecular mechanism that underpins the formation of petal color patterns and provide a foundation for the breeding of plants with green flowers.

关键词： flower development petal greening plastid conversion chlorophyll biosynthesis TCP transcription factors

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Computational simulations reveal the binding dynamics between human ACE2 and the receptor binding domain of SARS-CoV-2 spike protein

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Quantitative Biology 2021年第1期9卷 61-72页

作者： Cecylia SLupala Xuanxuan Li Jian Lei Hong Chen Jianxun Qi Haiguang Liu xiao-dong su Complex Systems Division Beijing Computational Science Research CenterBeijing 100193China Engingeering Physics Department Tsinghua UniversityBeijing 100084China State Key Laboratory of Biotherapy and Cancer Center National Clinical Research Center for GeriatricsWest China HospitalSichuan UniversityChengdu 610041China School of Life Sciences State Key Laboratory of Protein and Plant Gene Research and Biomedical Pioneering Innovation Center(BIOPIC)Peking UniversityBeijing 100871China CAS Key Laboratory of Pathogenic Microbiology and Immunology Institute of MicrobiologyChinese Academy of SciencesBeijing 100101China Physics Department Beijing Normal UniversityBeijing 100875China

Background:A novel coronavirus(the SARS-CoV-2)has been identified in January 2020 as the causal pathogen for COVID-19,a pandemic started near the end of *** Angiotensin converting enzyme 2 protein(ACE2)utilized by the SARS-CoV as a receptor was found to facilitate the infection of SARS-CoV-2,initiated by the binding of the spike protein to human ***:Using homology modeling and molecular dynamics(MD)simulation methods,we report here the detailed structure and dynamics of the ACE2 in complex with the receptor binding domain(RBD)of the SARS-CoV-2 spike ***:The predicted model is highly consistent with the experimentally determined structures,validating the homology modeling *** the binding interface reported in the crystal structures,novel binding poses are revealed from all-atom MD *** simulation data are used to identify critical residues at the complex interface and provide more details about the interactions between the SARS-CoV-2 RBD and human ***:Simulations reveal that RBD binds to both open and closed state of *** human ACE2 mutants and rat ACE2 are modeled to study the mutation effects on RBD binding to *** simulations show that the N-terminal helix and the K353 are very important for the tight binding of the complex,the mutants are found to alter the binding modes of the CoV2-RBD to ACE2.

关键词： SARS-CoV-2 COVID-19 ACE2 mutation molecular dynamics simulations

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High plasma fibrinogen concentration and platelet count unfavorably impact survival in non–small cell lung cancer patients with brain metastases

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Chinese Journal of Cancer 2014年第2期33卷 96-104页

作者： Jian-Fei Zhu Ling Cai Xue-Wen Zhang Yin-Sheng Wen xiao-dong su Tie-Hua Rong Lan-Jun Zhang State Key Laboratory of Oncology in South China Department of Thoracic surgery Sun Yat-sen University Cancer Center Department of Radiation Oncology Sun Yat-sen University Cancer Center Guangzhou Medical University

High expression of fibrinogen and platelets are often observed in non–small cell lung cancer(NSCLC) patients with local regional or distant metastasis. However, the role of these factors remains unclear. The aims of this study were to evaluate the prognostic significance of plasma fibrinogen concentration and platelet count, as well as to determine the overall survival of NSCLC patients with brain metastases. A total of 275 NSCLC patients with brain metastasis were enrolled into this study. Univariate analysis showed that high plasma fibrinogen concentration was associated with age ≥ 65 years(P = 0.011), smoking status(P = 0.009), intracranial symptoms(P = 0.022), clinical T category(P = 0.010), clinical N category(P = 0.003), increased partial thromboplastin time(P survival compared with those with high plasma fibrinogen concentration(median, 17.3 months versus 11.1 months; P ≤ 0.001). A similar result was observed for platelet counts(median, 16.3 months versus 11.4 months; P = 0.004). Multivariate analysis showed that both plasma fibrinogen concentration and platelet count were independent prognostic factors for NSCLC with brain metastases(R2 = 1.698, P sults suggest that high plasma fibrinogen concentration and platelet count indicate poor prognosis for NSCLC patients with brain metastases. Thus, these two biomarkers might be independent prognostic predictors for this subgroup of NSCLC patients.

关键词：血浆纤维蛋白原非小细胞肺癌血小板计数生存期患者浓度脑单因素分析

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Sensitivity impacts owing to the variations in the type of zero-range pairing forces on the fission properties using the density functional theory

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Nuclear Science and Techniques 2024年第3期35卷 198-207页

作者： Yang su Ze-Yu Li Li-Le Liu Guo-Xiang dong xiao-Bao Wang Yong-Jing Chen China Nuclear Data Center China Institute of Atomic EnergyBeijing 102413China School of Science Huzhou UniversityHuzhou 313000China

Using the Skyrme density functional theory,potential energy surfaces of^(240)Pu with constraints on the axial quadrupole and octupole deformations(q_(20)and q_(30))were *** volume-like and surface-like pairing forces,as well as a combination of these two forces,were used for the Hartree–Fock–Bogoliubov *** in the least-energy fission path,fission barrier,pairing energy,total kinetic energy,scission line,and mass distribution of the fission fragments based on the different forms of the pairing forces were analyzed and *** fission dynamics were studied based on the timedependent generator coordinate method plus the Gaussian overlap *** results demonstrated a sensitivity of the mass and charge distributions of the fission fragments on the form of the pairing *** on the investigation of the neutron-induced fission of^(239)Pu,among the volume,mixed,and surface pairing forces,the mixed pairing force presented a good reproduction of the experimental data.

关键词： Nuclear fission Density functional theory Pairing force Potential energy surfaces Fission fragment distribution

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