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Plasma big endothelin-1 is an effective predictor for ventricular arrythmias and end-stage events in primary prevention implantable cardioverter-defibrillator indication patients

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Journal of Geriatric Cardiology 2020年第7期17卷 427-433页

作者： xiao-Yao LI Shuang ZHAO xiao-Han FAN Ke-Ping CHEN Wei HUA Zhi-Min LIU xiao-di xue Bin ZHOU Shu ZHANG Arrhythmia Center State Key Laboratory of Cardiovascular DiseaseFuwai HospitalNational Center for Cardiovascular DiseasesChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina

Objective To investigate whether plasma big endothelin-1(ET-1) predicts ventricular arrythmias(VAs) and end-stage events in primary prevention implantable cardioverter-defibrillator(ICD) indication patigents. Methods In total, 207 patients fulfilling the inclusion criteria from Fuwai Hospital between January 2013 and December 2015 were retrospectively analyzed. The cohort was divided into three groups according to baseline plasma big ET-1 tertiles: tertile 1( 0.7 pmol/L, n = 70). The primary endpoints were VAs. The secondary endpoints were end-stage events comprising all-cause mortality and heart transplantation. Results During a mean follow-up period of 25.6 ± 13.9 months, 38(18.4%) VAs and 78(37.7%) end-stage events occurred. Big ET-1 was positively correlated with NYHA class(r = 0.165, P = 0.018), serum creatinine concentration(Scr;r = 0.147, P = 0.034), high-sensitivity C-reactive protein(hs-CRP;r = 0.217, P = 0.002), Lg NT-pro BNP(r = 0.463, P diastolic diameter(LVEDD;r = 0.234, P = 0.039) and negatively correlated with left ventricular ejection fraction(LVEF;r =-0.181, P = 0.032). Kaplan-Meier analysis showed that elevated big ET-1 was associated with increased risk of VAs and end-stage events(P dication patients, plasma big ET-1 levels can predict VAs and end-stage events and may facilitate ICD-implantation risk stratification.

关键词： Big endothelin-1 End-stage events Implantable cardioverter-defibrillator implantation Primary prevention Ventricular arrythmias

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The Fragmentation of the Female Selfhood in The Flight From the Enchanter

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Journal of Literature and Art Studies 2014年第5期4卷 325-337页

作者： XU Ming-ying SUI xiao-di AN xue-hua Dalian University of Technology Dalian China

Iris Murdoch is a renowned female novelist and philosopher in the 20th century English literature. In her literary creation, she has a preference for male narration and holds a reserved attitude to women＇s movements with reluctance to be considered as a feminist writer, which permits her realistic depiction of female characters and dispassionate thought on women＇s problems. This paper, with the interpretation and redefinition of the concepts as consciousness, identity, and self in Murdoch＇s philosophy, analyzes the fragmented self of three female figures in The Flight from the Enchanter （1956） respectively from the perspectives of self-consciousness, identity, and self and reveals that the fragmentation of female selfhood is mainly due to the overwhelming male dominance in the gender relationship.

关键词： Iris Murdoch identity female selfhood fragmentation

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Spin Transport under In-plane Electric Fields with different Orientations in Undoped InGaAs/AlGaAs Multiple Quantum Wells

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Chinese Physics Letters 2019年第7期36卷 82-85页

作者： xiao-di xue Yu Liu Lai-pan Zhu Wei Huang Yang Zhang xiao-lin Zeng Jing Wu Bo Xu Zhan-guo Wang Yong-hai Chen Wei-feng Zhang Henan Key Laboratory of Photovoltaic Materials Henan University Kaifeng 475004 Key Laboratory of Semiconductor Materials Science Institute of Semiconductors Chinese Academy of Sciences Beijing Key Laboratory of Low Dimensional Semiconductor Materials and Devices Beijing 100083 Center of Materials Science and Optoelectronics Engineering University of Chinese Academy of Sciences Beijing 100049 Beijing Institute of Nanoenergy and Nanosystems Chinese Academy of Sciences Beijing 100083 Science and Technology on Monolithic Integrated Circuits and Modules Laboratory Nanjing Electronic Devices Institute Nanjing 210016

The spin-polarized photocurrent is used to study the in-plane electric field dependent spin transport in undoped InGaAs/AlGaAs multiple quantum wells. In the temperature range of 77–297 K, the spin-polarized photocurrent shows an anisotropic spin transport under different oriented in-plane electric fields. We ascribe this characteristic to two dominant mechanisms: the hot phonon effect and the Rashba spin-orbit effect which is influenced by the in-plane electric fields with different orientations. The formulas are proposed to fit our experiments, suggesting a guide of potential applications and devices.

关键词： The spin-polarized photocurrent dependent spin transport applications and devices

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Observation of acoustic hybrid topological phases induced by the p-d orbital interactions

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Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 132-139页

作者： xiao Xiang Feng Gao Yu-Gui Peng Peng Wu Zong-Lin Li xue-Feng Zhu School of Physics and Innovation Institute Huazhong University of Science and Technology

In spinless systems,growing attention has recently been attracted to synthetic gauge fields,which redefine the fundamental crystal symmetries by utilizing the projective algebraic ***,synthetic gauge fields have been commonly investigated in single orbital systems,and explorations on hybrid orbitals remain elusive in ***,we report the experimental observation of hybrid topological phases induced by hybrid synthetic gauge flux,which is formed by the interaction between p and d orbitals embedded in acoustic *** breaking the translation symmetries of Lxand/or Ly,we unambiguously demonstrate the first-order M?bius edge states and higher-order corner *** work establishes a platform for seeking exotic topological phases induced by hybrid-orbitals interactions and initializing the framework of hybrid-orbitalsrelated topological *** applications can be anticipated in scenarios such as high-quality sensing and robust wave trapping due to the stepwise energy distribution of the hybrid topological phase.

关键词： topological insulator synthetic gauge field projective symmetry corner states

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Spontaneous Orientation Polarization of Anisotropic Equivalent dipoles Harnessed by Entropy Engineering for Ultra‑Thin Electromagnetic Wave Absorber

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Nano-Micro Letters 2025年第1期17卷 424-438页

作者： Honghan Wang Xinyu xiao Shangru Zhai Chuang xue Guangping Zheng Deqing Zhang Renchao Che Junye Cheng Liaoning Key Lab of Lignocellulose Chemistry and BioMaterials Liaoning Collaborative Innovation Center for Lignocellulosic BiorefinerySchool of Light Industry and Chemical EngineeringDalian Polytechnic UniversityDalian 116034People’s Republic of China School of Life Science and Biotechnology Dalian University of TechnologyDalian 116024People’s Republic of China Department of Mechanical Engineering Hong Kong Polytechnic UniversityHung HomKowloonHong Kong 999077People’s Republic of China School of Materials Science and Engineering Qiqihar UniversityQiqihar 161006People’s Republic of China Laboratory of Advanced Materials Shanghai Key Lab of Molecular Catalysis and Innovative MaterialsAcademy for Engineering&TechnologyFudan UniversityShanghai 200438People’s Republic of China Department of Materials Science Shenzhen MSU-BIT UniversityShenzhen 517182People’s Republic of China

The synthesis of carbon supporter/nanoscale high-entropy alloys(HEAs)electromagnetic response composites by carbothermal shock method has been identified as an advanced strategy for the collaborative competition engineering of conductive/dielectric *** migration modes within HEAs as manipulated by the electronegativity,valence electron configurations and molar proportions of constituent elements determine the steady state and efficiency of equivalent ***,enlightened by skin-like effect,a reformative carbothermal shock method using carbonized cellulose paper(CCP)as carbon supporter is used to preserve the oxygencontaining functional groups(O·)of carbonized cellulose fibers(CCF).Nucleation of HEAs and construction of emblematic shell-core CCF/HEAs heterointerfaces are inextricably linked to carbon metabolism induced by O·.Meanwhile,the electron migration mode of switchable electronrich sites promotes the orientation polarization of anisotropic equivalent *** virtue of the reinforcement strategy,CCP/HEAs composite prepared by 35%molar ratio of Mn element(CCP/HEAs-Mn_(2.15))achieves efficient electromagnetic wave(EMW)absorption of−51.35 dB at an ultra-thin thickness of 1.03 *** mechanisms of the resulting dielectric properties of HEAs-based EMW absorbing materials are elucidated by combining theoretical calculations with experimental characterizations,which provide theoretical bases and feasible strategies for the simulation and practical application of electromagnetic functional devices(e.g.,ultra-wideband bandpass filter).

关键词： High-entropy alloys Carbothermal shock Switchable electron migration modes Emblematic shell-core heterointerfaces Ultra-thin thickness

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慢性胃炎用调气活血法治疗后的胃动力变化——附86例患者胃排空功能疗效分析

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上海中医药杂志 2001年第7期35卷 18-19页

作者：张亚声刘小弟翁雪松上海市第一人民医院上海200080

为探讨调气活血法治疗慢性胃炎胃排空功能的作用机制 ,以SPECT法对照研究 5 0例慢性萎缩性胃炎 ,3 6例慢性浅表性胃炎患者胃排空功能变化及治疗前后疗效分析。结果 :慢性萎缩性胃炎组胃固体食物的排空功能明显低于正常组及浅表性胃炎组 ... 详细信息

为探讨调气活血法治疗慢性胃炎胃排空功能的作用机制 ,以SPECT法对照研究 5 0例慢性萎缩性胃炎 ,3 6例慢性浅表性胃炎患者胃排空功能变化及治疗前后疗效分析。结果 :慢性萎缩性胃炎组胃固体食物的排空功能明显低于正常组及浅表性胃炎组 ,治疗后胃动力明显提高 (P <0 0 5 )。提示调气活血法对慢性萎缩性胃炎者胃排空功能延迟。

关键词：调气活血法胃排空萎缩性胃炎双同位素标记试餐单光子发射断层扫描 SPECT 胃动力

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Modular assembly of complex C-alkyl glycoside enabled via cooperative NHC and photoredox catalysis

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Science China Chemistry 2025年

作者： Rui-Qiang Jiao Ming Li Xi Chen Mei-Ze Xu Tian ding xiao-Ping Gong Zhuo-Mei Li xue-Yuan Liu Yong-Min Liang State Key Laboratory of Applied Organic Chemistry Lanzhou University College of Chemistry and Chemical Engineering Northwest Normal University

C-Alkyl glycosides are found in natural products and are indispensable in drug development programs,owing to their diverse range of medicinal ***-component reactions involving glycosyl radical addition are well documented and proved efficient for the C-alkyl glycosides ***,multicomponent reactions for the rapid and controllable construction of structurally diversified C-alkyl glycosides in a single step remains a significant challenge due to the issues associated with balancing reactivity,compatibility,and ***,we report an NHC and photoredox co-catalyzed three-component method to access complex and valuable C-alkyl *** protocol exhibits broad substrate scope and excellent chemoand ***,nine types of sugars are compatible with this *** addition,the generality of this catalytic strategy was further highlighted by the potential for scalable production,the feasibility of further modifications of the products and its successful application in the late-stage functionalization of pharmaceutical skeletons.

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Role of nutrition in diabetes mellitus and infections

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World Journal of Clinical Cases 2025年第3期13卷 1-8页

作者： xue-Lu Yu Li-Yun Zhou xiao Huang Xin-Yue Li Ming-Ke Wang Ji-Shun Yang Naval Medical Center of PLA Naval Medical UniversityShanghai 200052China

In this editorial,we have commented on the article that has been published in the recent issue of World Journal of Clinical *** authors have described a case of unilateral thyroid cyst and have opined that the acute onset of infection may be linked to diabetes mellitus(DM).We have focused on the role of nutrition in the association between DM and *** with DM are at a high risk of infection,which could also be attributed to nutrition-related *** interventions for patients with diabetes are mainly based on a low-calorie diet,which can be achieved by adhering to a low-carbohydrate ***,dietary fiber supplementation is recommended to maintain the diversity of the gut ***,high-quality protein can prevent the increased risk of infection due to *** of vitamins C,vitamins A,vitamins D,and folic acid improves blood sugar control and facilitates immune *** deficiencies augment the risk of infection,but the relationship with diabetes is mostly U-shaped and a good intake should be maintained.

关键词： diabetes mellitus Infection Macronutrients Vitamins Minerals

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流动注射分析法测定生活饮用水中挥发酚

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疾病预防控制通报 2020年第6期35卷 68-70页

作者：朱亚娟李红叶左迪晓雪新疆生产建设兵团疾病预防控制中心乌鲁木齐830002

目的建立高效、方便、快捷的生活饮用水中挥发酚的测定方法。方法按照《生活饮用水标准检验方法水样的采集与保存》GB/T 5750-2006采集样品,采用全自动流动注射分析仪分析水中挥发酚;用挥发酚质控样做参照,比较流动注射分析法与4-氨基... 详细信息

目的建立高效、方便、快捷的生活饮用水中挥发酚的测定方法。方法按照《生活饮用水标准检验方法水样的采集与保存》GB/T 5750-2006采集样品,采用全自动流动注射分析仪分析水中挥发酚;用挥发酚质控样做参照,比较流动注射分析法与4-氨基安替比林三氯甲烷萃取分光光度法两种方法的优劣。结果流动注射分析法检测结果的线性范围为2~50μg/L,r=0.9996,低、中、高3个不同加标浓度,回收率为98.0%~102.0%,检出限0.80μg/L,准确度和精密度较好,满足实验要求;两种方法测定挥发酚质控样结果无明显差异。结论该方法具有样品量少、操作简便、安全可靠、检出限低、效率高的特点,适用于测定生活饮用水中挥发酚及大批量样品。

关键词：流动注射分析法生活饮用水挥发酚

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综合护理干预对中老年肝硬化合并上消化道出血患者的效果观察

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实用临床医药杂志 2017年第8期21卷 62-64页

作者：许宏赵郡刘洪严晓谢娣姜雪四川省绵阳市中心医院四川绵阳621000

目的探讨综合护理干预对中老年肝硬化合并上消化道出血患者的效果。方法选择本院收治的肝硬化合并消化道出血的中老年患者85例,按照住院期间护理方式不同,分为对照组以及观察组,分别实施常规护理及综合护理干预。观察2组患者在住院期间... 详细信息

目的探讨综合护理干预对中老年肝硬化合并上消化道出血患者的效果。方法选择本院收治的肝硬化合并消化道出血的中老年患者85例,按照住院期间护理方式不同,分为对照组以及观察组,分别实施常规护理及综合护理干预。观察2组患者在住院期间的心理状况、护理效果以及护理满意度等情况。结果观察组患者的SAS评分及SDS评分均显著低于对照组(P<0.05)。观察组24 h住院例数显著低于对照组(P<0.05)。观察组住院天数显著少于对照组(P<0.05)。观察组的治疗有效例数、护理满意度显著高于对照组(P<0.05)。结论中老年肝硬化合并上消化道出血患者实施综合护理干预,能有效的降低患者焦虑及抑郁心理,提高治疗的有效率及降低再出血率,提高护理满意度。

关键词：综合护理肝硬化上消化道出血

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