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Mesoporous TiO2 Nanofiber as Highly Efficient Sulfur Host for Advanced Lithium–Sulfur Batteries

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Chinese Journal of Mechanical Engineering 2019年第4期32卷 207-212页

作者： Xinyu shan Zuoxing guo Xu Zhang Jie Yang Lianfeng Duan Key Laboratory of Automobile Materials School of Materials Science and Engineering Jilin University Changchun 130025China Advanced Institute of Materials Science & Department of Materials Science and Engineering Changchun University of Technology Changchun 130012 China

Currently, lithium–sulfur batteries su er from several critical limitations that hinder their practical application, such as the large volumetric expansion of electrode, poor conductivity and lower sulfur utilization. In this work, TiO2 nanofibers with mesoporous structure have been synthesized by electrospinning and heat treating. As the host material of cathode for Li–S battery, the as prepared samples with novelty structure could enhance the conductivity of cathode composite, promote the utilization of sulfur, and relieve volume expansion for improving the electrochemical property. The initial discharge capacity of TiO2/S composite cathode is 703 mAh/g and the capacity remained at 652 mAh/g after 200 cycles at 0.1 C, whose the capacity retention remains is at 92.7%, demonstrating great prospect for application in high-performance Li–S batteries.

关键词： TiO2 nanofibers Mesoporous structure Lithium–sulfur batteries Cathode Electrochemical property

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适应新能源大基地的供气管网动态响应分析

油气与新能源 2025年第1期37卷 24-32页

作者：单蕾赵周丙郭杰肖勇王念榕史博会魏开华中国石油天然气股份有限公司规划总院北京100083 中国石油大学(北京)城市油气输配技术北京市重点实验室北京102249 中国石油天然气股份有限公司发展计划部北京100007

在全球能源转型和碳减排的背景下,新能源大基地发展迅速。由于风光发电具有间歇性强、波动性大、不稳定的特点,需要引入其他发电类型以平衡其波动性。天然气发电因其响应速度快、污染低,是平衡电网波动性的理想选择,但风、光发电不稳定... 详细信息

在全球能源转型和碳减排的背景下,新能源大基地发展迅速。由于风光发电具有间歇性强、波动性大、不稳定的特点,需要引入其他发电类型以平衡其波动性。天然气发电因其响应速度快、污染低,是平衡电网波动性的理想选择,但风、光发电不稳定性导致的气电用气需求的显著波动性也对供气管网的动态响应能力提出了新的挑战。基于天然气管网数值仿真软件TGNET(气体管道瞬态和稳态模拟计算软件),构建了新能源大基地在内的供气管网基础模型,探索了波动、平稳、限制等3种供气模式下,供气管网满足新能源大基地用气需求的瞬态响应能力。结果表明:波动供气模式下,跟随用气需求调整供气,会显著影响管网主干线的流量和压力,增加了压气站设备的负荷波动;平稳供气模式下,供气管网稳定性强,但供气余量大,需要新能源大基地具有较强的储气能力;限制供气模式下,需要联合末端管存,以满足新能源大基地的波动用气需求,但是应对临时大量用气需求能力较弱。因此,针对新能源大基地的用气需求,不仅需要供气管网具有较强的动态响应能力,还需要联合新能源大基地的储气能力进行综合分析,以确定合理的调度策略,并通过实时监控保障供气管网的稳定运行。

关键词： TGNET 天然气管网瞬态工况新能源大基地调峰

桦木醇-28-吲哚酯衍生物的设计合成及抗癌活性研究

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化学试剂 2025年第2期47卷 94-101页

作者：潘思文张英博张萌郭晓珊卜明王佳丰齐齐哈尔医学院病理学院黑龙江齐齐哈尔161006 齐齐哈尔医学院实验动物管理中心黑龙江齐齐哈尔161006 齐齐哈尔医学院护理学院黑龙江齐齐哈尔161006 齐齐哈尔医学院药学院黑龙江齐齐哈尔161006

为了寻找结构新颖、抗癌活性显著的先导化合物,以桦木醇为原料,设计并合成了一系列桦木醇-28-吲哚酯衍生物,并对合成产物进行了抗增殖活性测试、靶点预测和分子对接研究。结果表明,所有衍生物对3种癌细胞的抑制作用均优于桦木醇。其中,... 详细信息

为了寻找结构新颖、抗癌活性显著的先导化合物,以桦木醇为原料,设计并合成了一系列桦木醇-28-吲哚酯衍生物,并对合成产物进行了抗增殖活性测试、靶点预测和分子对接研究。结果表明,所有衍生物对3种癌细胞的抑制作用均优于桦木醇。其中,桦木醇-28-((6-氟)吲哚-3-)乙酸酯对3种癌细胞均表现出了低微摩尔级别的抗增殖活性(IC 50<10.00μmol/L),其对A549细胞的作用最强(IC 50=7.25μmol/L),是桦木醇的4.15倍。作用机制研究表明,上述化合物可能通过抑制PI3K-Akt通路发挥抗癌作用。总之,该化合物是一种具有良好抗癌活性的先导化合物,对其进一步的结构修饰和药理研究具有重要的意义。

关键词：桦木醇吲哚结构修饰抗癌活性 PI3K-Akt通路

Organic photodiodes:device engineering and applications

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Frontiers of Optoelectronics 2022年第4期15卷 91-123页

作者： Tong shan xiao Hou xiaokuan Yin xiaojun guo School of Electronic Information and Electrical Engineering Shanghai Jiao Tong UniversityShanghai 200240China

Organic photodiodes(OPDs)have shown great promise for potential applications in optical imaging,sensing,and communication due to their wide-range tunable photoelectrical properties,low-temperature facile processes,and excellent mechanical *** research work has been carried out on exploring materials,device structures,physical mechanisms,and processing approaches to improve the performance of OPDs to the level of their inorganic *** addition,various system prototypes have been built based on the exhibited and attractive features of *** is vital to link the device optimal design and engineering to the system requirements and examine the existing defciencies of OPDs towards practical applications,so this review starts from discussions on the required key performance metrics for diferent envisioned *** the fundamentals of the OPD device structures and operation mechanisms are briefy introduced,and the latest development of OPDs for improving the key performance merits is ***,the trials of OPDs for various applications including wearable medical diagnostics,optical imagers,spectrometers,and light communications are reviewed,and both the promises and challenges are revealed.

关键词： Organic photodiodes Wearable electronics Photoplethysmography Optical imagers Spectrometers Optical communications

柴芍开郁汤通过补体C3/C3aR通路改善抑郁模型大鼠海马神经炎症的研究

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中国中药杂志 2025年第1期50卷 1-9页

作者：唐璎娟郭海鹏邹蔓姝韩远山刘峻呈王宇红湖南中医药大学科技创新中心湖南长沙410208 湖南中医药大学第一附属医院湖南长沙410007 抑郁类疾病中医药防治湖南省重点实验室湖南长沙410208 彭州市中医医院四川成都611930

基于补体C3(C3)/补体成分C3受体(C3aR),探讨柴芍开郁汤改善抑郁模型大鼠海马神经炎症的作用机制。SD大鼠60只,随机分为空白组,模型组,柴芍开郁汤高、中、低剂量组,阳性药组,每组10只,除空白组外,其余各组采用慢性不可预知应激(CUMS)法... 详细信息

基于补体C3(C3)/补体成分C3受体(C3aR),探讨柴芍开郁汤改善抑郁模型大鼠海马神经炎症的作用机制。SD大鼠60只,随机分为空白组,模型组,柴芍开郁汤高、中、低剂量组,阳性药组,每组10只,除空白组外,其余各组采用慢性不可预知应激(CUMS)法构建抑郁模型。以蔗糖偏嗜度、旷场实验、强迫游泳实验、水迷宫实验检测各组大鼠抑郁样行为变化。以酶联免疫吸附测定法(ELISA)检测大鼠血清炎症因子水平;苏木素-伊红(HE)染色和Nissl染色观察海马神经元病理损伤;高尔基染色观察海马神经元树突棘损伤情况;免疫荧光、Western blot检测小胶质细胞标记物离子钙结合衔接分子1(Iba-1)及大鼠海马中C3/C3aR蛋白的表达情况。行为学结果显示,与模型组比较,柴芍开郁汤能显著提高抑郁大鼠糖水偏嗜度,增加自主活动距离和活动次数,缩短强迫游泳的不动时间和定位航行的成功潜伏期,延长空间探索在目标象限停留的时间;ELISA结果显示,抑郁模型大鼠海马中炎症因子含量明显高于空白组,经柴芍开郁汤干预后,炎症因子含量明显降低;此外,柴芍开郁汤还能缓解海马组织胞体肿胀、排列松散等病理损伤;在Western blot实验中,模型组的C3、C3aR蛋白表达水平相较于空白组有所升高,而柴芍开郁汤能下调C3、C3aR的表达;免疫荧光结果显示,与模型组比较,经柴芍开郁汤和阳性药干预后小胶质细胞标记物Iba-1的荧光强度明显降低。柴芍开郁汤的抗抑郁作用可能与其下调C3/C3aR信号通路相关蛋白,进而缓解海马炎症反应有关。

关键词：抑郁症海马神经炎性损伤 C3/C3aR 柴芍开郁汤

A new energy efficient management approach for wireless sensor networks in target tracking

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Defence Technology（防务技术） 2021年第3期17卷 932-947页

作者： Ce Pang Gong-guo Xu Gan-lin shan Yun-pu Zhang Army Engineering University Hebei Shijiazhuang050003China

This paper mainly studied the problem of energy conserving in wireless sensor networks for target tracking in defensing combats. Firstly, the structures of wireless sensor nodes and networks were illustrated;Secondly, the analysis of existing energy consuming in the sensing layer and its calculation method were provided to build the energy conserving objective function;What’s more, the other two indicators in target tracking, including target detection probability and tracking accuracy, were combined to be regarded as the constraints of the energy conserving objective function. Fourthly, the three energy conserving approaches, containing optimizing the management scheme, prolonging the time interval between two adjacent observations, and transmitting the observations selectively, were introduced;In addition, the improved lion algorithm combined with the Logistic chaos sequence was proposed to obtain sensor management schemes. Finally, simulations had been made to prove the effectiveness of the proposed methods and algorithm.

关键词： Wireless sensor networks Target searching Target tracking Energy efficiency Lion algorithm

Using MALDI-TOF MS coupled with a high-mass detector to directly analyze intact proteins in thyroid tissues

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Science China Chemistry 2018年第7期61卷 871-878页

作者： shan-shan Wang Yun-Jun Wang Jing Zhang Jun Xiang Tuan-Qi Sun Yin-Long guo State Key Laboratory of Organometallic Chemistry and National Center for Organic Mass Spectrometry in shanghai Center for Excellence in Molecular Synthesis Shanghai Institute of Organic Chemistry University of Chinese Academy of Sciences Chinese Academy of Sciences Department of Head and Neck Surgery Fudan University Shanghai Cancer Center Department of Oncology Shanghai Medical College Fudan University

Protein analysis is vital for biological and clinical research, but the measurement of unseparated, intact and high-mass proteins is also a challenging task by mass spectrometry-based methods. Here, we present a protocol for rapid and high-throughput analysis of intact proteins in tissue samples using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry（MALDITOF MS） combined with a high-mass detector platform. The method involves tissue specimens that undergo a simple protein extraction before MALDI-MS analysis. Using this method, the high abundance proteins in human thyroid carcinoma and paracarcinoma tissues were successfully investigated, and the mass spectra of the tissues of the 30 illustrated thyroid cancers showed remarkable differences. The peak intensity revealed a significant increase in human albumin in thyroid carcinoma tissues（p＆lt;0.05）. To validate the feasibility and credibility of this method, label-free proteomics quantitative analysis and Western blotting were used to relatively quantify the proteins in these tissues. Those results demonstrated a nearly 3-fold difference in human albumin levels between thyroid carcinoma and para-carcinoma tissues, which were consistent with the results of our method. The advantages of our method are easy sample handling, remarkable reproducibility and the ability to analyze high-mass proteins without digestion, which make them have the potential to be used in biological research and in clinical practice.

关键词： matrix-assisted laser desorption ionization time of flight mass spectrometry intact proteins analysis thyroid carcinoma high-mass detector

Cryptic diversity and rampant hybridization in annual gentians on the Qinghai-Tibet Plateau revealed by population genomic analysis

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Plant Diversity 2024年第2期46卷 194-205页

作者： Peng-Cheng Fu Qiao-Qiao guo Di Chang Qing-Bo Gao shan-shan Sun School of Life Science Luoyang Normal UniversityLuoyang 471934PR China Key Laboratory of Adaptation and Evolution of Plateau Biota Northwest Institute of Plateau BiologyChinese Academy of SciencesXining 810001PR China

Understanding the evolutionary and ecological processes involved in population differentiation and speciation provides critical insights into biodiversity formation. In this study, we employed 29,865 single nucleotide polymorphisms(SNPs) and complete plastomes to examine genomic divergence and hybridization in Gentiana aristata, which is endemic to the Qinghai-Tibet Plateau(QTP) region. Genetic clustering revealed that G. aristata is characterized by geographic genetic structures with five clusters(West, East, Central, South and North). The West cluster has a specific morphological character(i.e., blue corolla) and higher values of FSTcompared to the remaining clusters, likely the result of the geological barrier formed by the Yangtze River. The West cluster diverged from the other clusters in the Early Pliocene;these remaining clusters diverged from one another in the Early Quaternary. Phylogenetic reconstructions based on SNPs and plastid data revealed substantial cyto-nuclear conflicts. Genetic clustering and D-statistics demonstrated rampant hybridization between the Central and North clusters,along the Bayankala Mountains, which form the geological barrier between the Central and North clusters. Species distribution modeling demonstrated the range of G. aristata expanded since the Last Interglacial period. Our findings provide genetic and morphological evidence of cryptic diversity in G. aristata, and identified rampant hybridization between genetic clusters along a geological *** findings suggest that geological barriers and climatic fluctuations have an important role in triggering diversification as well as hybridization, indicating that cryptic diversity and hybridization are essential factors in biodiversity formation within the QTP region.

关键词： Gentiana aristata Hybrid zone Qinghai-Tibet Plateau Plastome Nuclear SNPs

Sensor radiation interception risk control in target tracking

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Defence Technology（防务技术） 2020年第3期16卷 695-704页

作者： Ce Pang Gan-lin shan Wei-ning Ma Gong-guo Xu Army Engineering University Shijiazhuang CampusShijiazhuangHebei050003China

This paper is mainly on the problem of radiation interception risk control in sensor network for target ***,the sensor radiation interception risk is defined as the product of the interception probability and the cost caused by the ***,the radiation interception probability model and cost model are established,based on which the calculation method of interception risk can be ***,a sensor scheduling model of radiation risk control is established,taking the minimum interception risk as the objective *** the Hungarian algorithm is proposed to obtain sensor scheduling ***,simulation experiments are mad to prove the effectiveness of the methods proposed in this paper,which shows that compared with the sensor radiation interception probability control method,the interception risk control method can keep the sensor scheduling scheme in low risk as well as protect sensors of importance in the sensor network.

关键词： Radio frequency stealth Target tracking Interception probability Interception risk Hungary algorithm