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Insomnia Burden among Informal Caregivers of Hospitalized Lung Cancer Patients and Its Influencing Factors

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Biomedical and Environmental Sciences 2023年第8期36卷 715-724页

作者： LI Chun Yan SONG Yu Jian ZHAO Lan DENG mu Hong LI rui Xin ZHANG xiao Ling LI Qiong Xuan SHI Ying LUAN Heng Yu SUN Yuan Yuan HU Yi SAI xiao Yong Department of Respiratory The First Medical Center of PLA General HospitalBeijing 100853China Department of Statistics and Epidemiology The Graduate School of the Chinese PLA General HospitalBeijing 100853China Department of Disease Prevention Marine Police HospitalJiaxing 314000ZhejiangChina Department of Internal Oncology The First Medical Center of PLA General HospitalBeijing 100853China

Objective This study aimed to reveal the insomnia burden and relevant influencing factors among informal caregivers(ICs)of hospitalized patients with lung *** A cross-sectional study on ICs of hospitalized patients with lung cancer was conducted from December 31,2020 to December 31,***’burden was assessed using the Caregiver Reaction Assessment(CRA),Hospital Anxiety and Depression Scale(HADS),and Insomnia Severity Index(ISI).Linear and logistic regression models were used to identify the influencing *** Among 289 ICs of hospitalized patients with lung cancer,83(28.72%),53(18.34%),and 14(4.84%)ICs experienced mild,moderate,and severe insomnia,*** scores concerning self-esteem,lack of family support,financial problems,disturbed schedule,and health problems were 4.32±0.53,2.24±0.79,2.84±1.14,3.63±0.77,and 2.44±0.95,*** with higher Activities of Daily Living Scale(ADLS)scores were associated with a lower risk of insomnia,with an odd ratio(OR)and 95%confidence interval(CI)of 0.940(0.898–0.983).Among the ICs,female gender(OR=2.597),alcohol consumption(OR=3.745),underlying medical conditions(OR=11.765),long-term caregiving experience(OR=37.037),and higher monthly expenses(OR=5.714)were associated with a high risk of *** Of the hospitalized patients with lung cancer,51.9%experienced ***’ADL,ICs gender,alcohol consumption,underlying medical conditions,caregiving duration,and monthly expenses were influencing ***,prompt screening and early intervention for ICs of patients with lung cancer is necessary.

关键词： Informal caregivers Insomnia Risk factors Cross-sectional study Lung cancer

Facile one-step synthesis of PdPb nanochains for high-performance electrocatalytic ethanol oxidation

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Rare Metals 2020年第7期39卷 792-799页

作者： Yong Zhang xiao-Lei Yuan Feng-Lei Lyu Xu-Chun Wang xiao-Jing Jiang mu-Han Cao Qiao Zhang Institute of Functional Nano and Soft Materials FUNSOM Jiangsu Key Laboratory for Carbon-Based Functional Materials and DevicesSoochow UniversitySuzhou 215123China School of Chemistry and Chemical Engineering Nantong UniversityNantong 226019China

The widespread application of direct ethanol fuel cells is hampered due to the low activity,high cost and poor operation durability of electrocatalysts for ethanol oxidation reaction(EOR).Herein,we report a one-pot synthetic method to synthesize PdPb3 nanochains with well-defined shape,size and composition via a solution-phase reduction *** morphology,composition distribution and structure characteristics of PdPb3 nanochains were investigated by transmission electron microscopy,X-ray photoelectron spectroscopy and X-ray *** to the unique structure,the as-obtained PdPb3 nanochains can manifest much higher mass activity(2523 mA·mg-1)and higher operation durability than commercial Pd/C(1272 mA·mg-1)during the EOR *** importantly,further CO-stripping measurements indicate that the incorporation of Pb species could favor the oxidative removal of CO intermediates on the Pd electrode at the negative potential and enhance the EOR activity and stability,making it possible to develop highly active and durable electrocatalysts.

关键词： PdPb Nanochains Ethanol oxidation reaction CO stripping Electrocatalysts

Histological Risk Factors for Lymph Node Metastasis in pT1 Colorectal Cancer:Does Submucosal Invasion Depth Really Matter?

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Current Medical Science 2024年第5期44卷 1026-1035页

作者： Bing YUE Mei JIA rui XU Guang-yong CHEN mu-lan JIN Department of Pathology Beijing Friendship HospitalCapital Medical UniversityBeijing100050China Department of Pathology Beijing Chaoyang HospitalCapital Medical UniversityBeijing100015China

Objective After endoscopic resection of colorectal cancer with submucosal invasion(pT1 CRC),additional surgical treatment is recommended if deep submucosal invasion(DSI)is *** study aimed to further elucidate the risk factors for lymph node metastasis(LNM)in patients with pT1 CRC,especially the effect of DSI on *** Patients with pT1 CRC who underwent lymph node dissection were *** Chi-square test and multivariate logistic regression were used to analyze the relationship between clinicopathological characteristics and *** submucosal invasion depth(SID)was measured via 4 methods and analyzed with 3 cut-off *** Twenty-eight of the 239 patients presented with LNM(11.7%),and the independent risk factors for LNM included high histological grade(P=0.003),lymphovascular invasion(LVI)(P=0.004),intermediate to high budding(Bd 2/3)(P=0.008),and cancer gland rupture(CGR)(P=0.008).Moreover,the SID,width of submucosal invasion(WSI),and area of submucosal invasion(ASI)were not significantly *** one,two,three or more risk factors were identified,the LNM rates were 1.1%(1/95),12.5%(7/56),and 48.8%(20/41),*** Indicators such as the SID,WSI,and ASI are not risk factors for LNM and are subjective in their measurement,which renders them relatively inconvenient to apply in clinical *** contrast,histological grade,LVI,tumor budding and CGR are relatively straightforward to identify and have been demonstrated to be statistically *** would be prudent to focus on these histological factors rather than subjective measurements.

关键词： lymph node metastasis early colorectal cancer lymph node dissection submucosal invasion depth tumor budding cancer gland rupture

Cobalt-loaded carbon nanotubes boosted aerobic ciprofloxacin transformation driven by sulfide:A comprehensive mechanism investigation

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Chinese Chemical Letters 2024年第3期35卷 127-134页

作者： Han-Qing Zhao Peili Lu Fei Chen Chen-Xuan Li rui Yan Yang mu State Key Laboratory of Coal Mine Disaster Dynamics and Control Chongqing UniversityChongqing 400044China CAS Key Laboratory of Urban Pollutant Conversion Department of Environmental Science and EngineeringUniversity of Science and Technology of ChinaHefei 230026China Key Laboratory of the Three Gorges Reservoir Region's Eco-Environment College of Environment and EcologyChongqing UniversityChongqing 400045China College of Resources and Environmental Engineering Hefei University of TechnologyHefei 230009China

Sulfide oxidation under aerobic conditions can produce active oxygen for the transformation of organic pollutants in aquatic ***,the catalytic performance of transition metal-supported carbon material on this process is poor *** study found that Co-loaded carbon nanotubes(CNTs)was able to realize the efficient aerobic transformation of antibiotic ciprofloxacin(CIP)by sulfide,with the pseudo-first order reaction rate constant improved from 0.013 h^(-1)without catalyst to 0.44–0.71 h^(-1)with 100 mg/L Co-loaded *** oxygen(^(1)O_(2))was the main active specie playing key roles in the process of CIP aerobic transformation with presence of Co-loaded *** studies indicated that the excellent electron transfer ability of Co-loaded CNTs might play an important role to promote the electron transfer and facilitate the formation of intermediate H_(2)O_(2)and^(1)O_(2).Additionally,the Co-loaded CNTs/sulfide system effectively reduced the acute toxicity of organic pollutant,and Co-loaded CNTs showed remarkable cycling stability and negligible *** study gives a better understanding for the Co-loaded CNTs mediated aerobic antibiotics transformation by sulfide,and provide a reference for the application of Co-loaded carbon materials on organics aerobic transformation by sulfide.

关键词： Ciprofloxacin Aerobic transformation Co-loaded carbon nanotubes Sulfide Singlet oxygen

Enhancement of ductility and improvement of abnormal Goss grain growth of magnetostrictive Fe–Ga rolled alloys

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International Journal of Minerals,Metallurgy and Materials 2018年第4期25卷 444-452页

作者： Ji-heng Li Chao Yuan Xing mu xiao-qian Bao Xue-xu Gao State Key Laboratory for Advanced Metals and Materials University of Science and Technology Beijing

The influences of initial microstructures on the mechanical properties and the recrystallization texture of magnetostrictive 0.1 at% Nb C-doped Fe83 Ga17 alloys were investigated. The directionally solidified columnar-grained structure substantially enhanced the tensile elongation at intermediate temperatures by suppressing fracture along the transverse boundaries. Compared with tensile elongations of 1.0% at 300℃ and 12.0% at 500℃ of the hot-forged equiaxed-grained alloys, the columnar-grained alloys exhibited substantially increased tensile elongations of 21.6% at 300℃ and 46.6% at 500℃. In the slabs for rolling, the introduction of 〈001〉-oriented columnar grains also promotes the secondary recrystallization of Goss grains in the finally annealed sheets, resulting in an improvement of the saturation magnetostriction. For the columnar-grained specimens, the inhomogeneous microstructure and disadvantage in number and size of Goss grains are improved in the primarily annealed sheets, which is beneficial to the abnormal growth of Goss grains during the final annealing process.

关键词： magnetostriction iron-gallium alloys columnar grain ductility abnormal grain growth

Efficacy and safety of S-1 maintenance therapy in advanced nonsmall- cell lung cancer patients

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World Journal of Clinical Cases 2020年第21期8卷 5172-5179页

作者： xiao-Wei Cheng Wen-Hua Leng Chun-Ling mu Department of Respiratory and Critical Care Medicine Panzhihua Central HospitalPanzhihua 617067Sichuan ProvinceChina Department of Ultrasound Panzhihua Central HospitalPanzhihua 617067Sichuan ProvinceChina

BACKGROUND Previous reports have demonstrated that S-1 has remarkable effects in the maintenance treatment of advanced non-small-cell lung cancer(NSCLC),and has less toxic and side effects than conventional *** To investigate the efficacy and safety of S-1 maintenance therapy in patients with advanced *** Ninety-four patients with NSCLC admitted to our hospital from September 2015 to April 2018 were included in the study and divided into the S-1 group(47 cases)and the gemcitabine group(47 cases)by random digital table *** S-1 group was treated with S-1,while the gemcitabine group received gemcitabine *** clinical efficacy and quality of life of the patients after treatment in the two groups were *** There was no significant difference in the total effectiveness rate between the two groups(P=0.519).The quality-of-life scores indicated that there was no significant difference between the two groups in terms of four dimensions of the GQOLI-74 questionnaire(P=0.518,0.094,0.338,0.418).The incidence of nausea and vomiting,granulocytopenia and diarrhea in the S-1 group was significantly lower than that in the gemcitabine group(P=0.001,0.001 and 0.001,respectively).There was no significant difference in the incidence of thrombocytopenia(P=0.366),the progression-free survival(P=0.064),and the survival between the two groups(P=0.050).CONCLUSION S-1 maintenance therapy shows a significant therapeutic effect in patients with advanced *** has the same clinical efficacy as gemcitabine,but with less toxic and side effects than conventional drugs.

关键词： Advanced non-small cell lung cancer Maintenance therapy S-1 Gemcitabine Efficacy Toxic and side effects

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轨道交通钢混组合连续梁及剪力件设计探讨

价值工程 2025年第1期44卷 71-73页

作者：李牧中铁上海设计院集团有限公司上海200040

由于钢混组合梁结构可以充分发挥混凝土和钢结构的性能优势,因此在轨道交通桥梁设计中逐步得到推广。目前对于轨道交通组合梁上部结构构造设计及计算参考较少,不同设计标准、规范针对剪力件的计算仍存在区别,因此有必要对上述问题进行... 详细信息

由于钢混组合梁结构可以充分发挥混凝土和钢结构的性能优势,因此在轨道交通桥梁设计中逐步得到推广。目前对于轨道交通组合梁上部结构构造设计及计算参考较少,不同设计标准、规范针对剪力件的计算仍存在区别,因此有必要对上述问题进行分析探讨。本文结合国内某轨道交通项目(45+70+45)m钢混组合连续梁的设计,通过有限元软件建模计算,分析钢混组合梁的受力特点,并针对国内外不同规范对于钢混组合梁剪力件的抗剪承载力计算公式进行比较及探讨,以期为同类型桥梁设计计算提供一定参考。

关键词：轨道交通桥梁钢混组合连续梁剪力连接件焊钉结构分析

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Current Sheet Formation in Weakly Ionized Plasmas

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Chinese Physics Letters 2001年第6期18卷 788-789页

作者： JI Hai-Sheng LI xiao-Qing SONG mu-Tao Purple Mountain Observatory Chinese Academy of ScienceNanjing 210008 Department of Physics Nanjing Normal UniversityNanjing 210087 National Astronomical Observatories Chinese Academy of SciencesBeijing 100080

Using the two fluid model,the problem of two-dimensional steady-state magnetic reconnection in incompressible resistive weakly ionized plasmas is *** the strong-coupling condition such as in the Sun's photosphere,it allows us to express the current sheet *** this case the current sheet scales as η^(1/2).Then this model is used to understand magnetic flux cancellation which is observed in the Sun's *** account for a canceling flux of 1 × 10^(18)Max in a time interval of 77 min,the width of the current sheet is about ten kilometers.

关键词： weakly Weakly coupling

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数值模拟技术在阜新地区地下水变幅中的应用

水利技术监督 2025年第1期 208-211,218页

作者：张目辽宁省辽河防洪工程有限责任公司辽宁沈阳110000

本研究运用地下水数值模拟技术,对位于辽宁省的阜新市地区实施不同地下水抽取方案所引发的水位波动进行了定量分析。模拟结果显示,在设定条件下,即当地浅层地下水年抽取量介于135万~152万m^(3)之间,深层地下水年抽取量介于26万~65万m^(3... 详细信息

本研究运用地下水数值模拟技术,对位于辽宁省的阜新市地区实施不同地下水抽取方案所引发的水位波动进行了定量分析。模拟结果显示,在设定条件下,即当地浅层地下水年抽取量介于135万~152万m^(3)之间,深层地下水年抽取量介于26万~65万m^(3)之间时,预测该区域地下水位波动幅度相对较小。据此,地下水位埋藏深度得以维持在约1.5~3.5m的范围内,从而确保了该地区地下水资源的可持续利用,满足区域内的开采需求。

关键词：数值模拟地下水开采方案地下水位变幅阜新