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A Simplified Nonlinear Model of Vertical Vortex-Induced Force on Box Decks for Predicting Stable Amplitudes of Vortex-Induced Vibrations

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Engineering 2017年第6期3卷 854-862页

作者： Le-Dong Zhu xiao-liang meng Lin-Qing Du Ming-Chang Ding State Key Laboratory of Disaster Reduction in Civil Engineering & Department of Bridge Engineering College of Civil Engineering & Key Laboratory for Wind Resistance Technology of Bridges of Ministry of Transport Tongji University Shanghai 200092 China Shanghai Urban Construction Municipal Engineering (Croup) Co. Ltd. Shanghai 200065 China Tongji Architectural Design (Group) Co. Ltd. Shanghai 200092 China Highway Planning Survey Design and Research Institute Sichuan Provincial Transport Department Chengdu 610041 China

Wind-tunnel tests of a large-scale sectional model with synchronous measurements of force and vibration responses were carried out to investigate the nonlinear behaviors of vertical vortex-induced forces （VIFs） on three typical box decks （i.e., fully closed box, centrally slotted box, and semi-closed box）. The mechanisms of the onset, development, and self-limiting phenomenon of the vertical vortex-induced vibration （VlV） were also explored by analyzing the energy evolution of different vertical VIF components and their contributions to the vertical VIV responses. The results show that the nonlinear components of the vertical VIF often differ from deck to deck; the most important components of the vertical VIF, governing the stable amplitudes of the vertical VIV responses, are the linear and cubic components of velocity contained in the self-excited aerodynamic damping forces. The former provides a constant negative damping ratio to the vibration system and is thus the essential power driving the development of the VIV amplitude, while the latter provides a positive damping ratio proportional to the square of the vibration velocity and is actually the inherent factor making the VIV amplitude self-limiting. On these bases, a universal simplified nonlinear mathematical model of the vertical VIF on box decks of bridges is presented and verified in this paper; it can be used to predict the stable amplitudes of the vertical VIV of long-span bridges with satisfactory accuracy.

关键词： Box deck of bridge Vertical vortex-induced vibration Vertical vortex-induced force Simplified nonlinear model Wind-tunnel test Large-scale sectional model Synchronous measurement of force and vibration

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Analysis of the urinary peptidome associated with Helicobacter pylori infection

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World Journal of Gastroenterology 2011年第5期17卷 618-624页

作者： Di xiao Fan-liang meng Li-Hua He Yi-Xin Gu Jian-Zhong Zhang National Institute for Communicable Disease Controland Prevention Chinese Center for Disease Control and Pre-vention Beijing 102206 China

AIM： To investigate the relationship between urinary peptide changes and Helicobacter pylori （H. pylorl） infection using urinary peptidome profiling. METHODS： The study was performed in volunteers （n = 137） who gave informed consent. Urinary peptides were enriched by magnetic beads based weak cation exchange chromatography＇and spectrums acquired by matrix-assisted laser desorption/ionization time-of-flight （MALDI-TOF） mass spectrometry （MS）. ClinProTools bioinformatics software was used for statistical analysis and the recognition of peptide patterns. The marker peptides were identified by LTQ Obitrap XL tandem MS. RESULTS： Approximately 50 proteins or peptides which loaded onto the magnetic beads were detected by MAL-DI-TOF MS. By optimizing the parameters of the model, the Genetic Algorithm model had good recognition capability （97%） and positive predictive value （94%）. Based on the model, 2 markers with molecular masses of 6788 and 1912 Da were found that differentiated between H. pylori positive and negative volunteers. The m/z 1912 sequence was parsed as SKQFTSSTSYN- RGDSTF. The peptide was identified as isoform 1 of the fibrinogen a chain precursor, whose concentration in urine was markedly higher in H. pylori infected volunteers than in H. pylori non-infected ones. CONCLUSION： The appearance of urinary fibrinogen degradation products is caused by an active H. pyloriinduced process.

关键词： Urinary peptidome profiling MB-matrix-assisted laser desorption/ionization time-of-flight massspectrometry Helicobacter pylori Fibrinogen degrada-tion products

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Treatment and Outcome of Epileptogenic Temporal Cavernous Malformations

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Chinese Medical Journal 2015年第7期128卷 909-913页

作者： Yong-Zhi Shan xiao-Tong Fan liang meng Yang An Jian-Kun Xu Guo-Guang Zhao Department of Neurosurgery Xuanwu Hospital Capital Medical University Beijing 100053 China

Background： The aim of this study is to explore the treatment and outcome ofepileptogenic temporal lobe cavernous malformations （CMs）. Methods： We analyzed retrospectively the profiles of 52 patients diagnosed as temporal lobe CMs associated with epilepsy. Among the 52 cases, 11 underwent a direct resection of CM along with the adjacent zone of hemosiderin rim without electrocorticogram （ECoG） monitoring while the other 41 cases had operations under the guidance of ECoG. Forty-six patients were treated by lesionectomy ＋ hemosiderin rim while the other six were treated by lesionectomy ＋ hemosiderin rim along with extended epileptogenic zone resection. The locations of lesions, the duration of illness, the manifestation, the excision ranges and the outcomes of postoperative follow-up were analyzed, respectively. Results： All of the 52 patients were treated by microsurgery. There was no neurological deficit through the long-term follow-up. Outcomes of seizure control are as follows： 42 patients （80.8%） belong to Engel Class I, 5 patients （9.6%） belong to Engel Class II, 3 patients （5.8%） belong to Engel Class Ill and 2 patients （3.8%） belong to Engel Class IV. Conclusion： Patients with epilepsy caused by temporal CMs should be treated as early as possible. Resection of the lesion and the surrounding hemosiderin zone is necessary. Moreover, an extended excision of epileptogenic cortex or cerebral lobes is needed to achieve a better prognosis if the ECoG indicates the existence of an extra epilepsy onset origin outside the lesion itself.

关键词： Cavernous Mallbrmation Electrocorticogram Epilepsy Surgery Temporal Lobe

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美国顶级高校智库的信息服务调查

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图书馆论坛 2017年第8期37卷 143-150页

作者：梁宵萌北京大学信息管理系

文章通过网站调研方式,从网络信息组织、信息公开、移动信息服务三个角度调查美国25家顶级高校智库的信息服务情况,总结出美国顶级高校智库的四大信息服务启示:依托图书馆资源开展信息服务;信息成果类型多元化;信息传播渠道社会媒体化;... 详细信息

文章通过网站调研方式,从网络信息组织、信息公开、移动信息服务三个角度调查美国25家顶级高校智库的信息服务情况,总结出美国顶级高校智库的四大信息服务启示:依托图书馆资源开展信息服务;信息成果类型多元化;信息传播渠道社会媒体化;信息服务订制化。

关键词：美国高校智库信息服务网络信息组织移动信息服务社会媒体订制

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脉冲电化学氧化降解亚甲基蓝

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中国环境科学 2018年第5期38卷 1767-1773页

作者：雷佳妮李晓良袁孟孟徐浩延卫西安交通大学环境科学与工程系陕西西安710049

为改善传统电化学氧化的缺陷,将脉冲式供电引入到电化学氧化中,利用Ti/Pb O_2-PVDF电极,对亚甲基蓝(MB)模拟染料废水进行电化学氧化降解处理,分析初始浓度、脉冲电压、脉冲频率、占空比和Na Cl浓度等因素对降解效果的影响.结果表明,当M... 详细信息

为改善传统电化学氧化的缺陷,将脉冲式供电引入到电化学氧化中,利用Ti/Pb O_2-PVDF电极,对亚甲基蓝(MB)模拟染料废水进行电化学氧化降解处理,分析初始浓度、脉冲电压、脉冲频率、占空比和Na Cl浓度等因素对降解效果的影响.结果表明,当MB初始浓度为100mg/L,脉冲电压为5.5V,脉冲频率为1500Hz,占空比为50%,Na Cl浓度为0.01mol/L时,降解效果最好.在相同条件下,比较脉冲与直流两种供电模式下的电化学氧化效果.结果表明脉冲模式下,90min内MB脱色率、COD去除率及电流效率分别为100%、94.5%和60.1%,均高于直流模式;脉冲模式下能耗为0.013k Wh/g COD,远小于直流模式的0.107k Wh/g COD.上述结果表明脉冲供电模式相比于直流供电模式具有明显优势.

关键词：染料废水二氧化铅电化学氧化脉冲供电模式亚甲基蓝

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我国科研人员对图书馆开展出版服务的认知及需求调查

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图书馆论坛 2017年第4期37卷 23-31页

作者：刘兹恒苗美娟梁宵萌北京大学信息管理系

文章利用问卷形式调研我国科研人员对学术图书馆出版服务的认知及需求情况。调查发现:我国科研人员对图书馆出版服务的认识不足,但需求明显;学科及内部因素是影响科研人员选择图书馆出版的重要因素;科研人员对出版类型和出版服务需求多... 详细信息

文章利用问卷形式调研我国科研人员对学术图书馆出版服务的认知及需求情况。调查发现:我国科研人员对图书馆出版服务的认识不足,但需求明显;学科及内部因素是影响科研人员选择图书馆出版的重要因素;科研人员对出版类型和出版服务需求多样,各有侧重;科研人员在服务收费上存在较为明显的差异。文章认为学术图书馆参与出版服务有其必要性、重要性和有利条件,学术图书馆应将自身定位为辅助传统学术出版,着眼于学术作品的公开传播、共享及永久保存,主动提供学术出版服务。

关键词：图书馆出版服务科研人员

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防城港某市政道路裂缝成因及处理

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企业科技与发展 2010年第16期 205-206页

作者：梁小萌广西玉林水利电力勘测设计研究院

文章介绍了广西防城港某市政道路工程的基本情况,分析了路面结构早期损坏的特点和原因,沥青道路路面裂缝的形成、危害、种类及产生原因,提出了对裂缝进行预防和处理的措施,并介绍了路面材料养护技术的应用,对新材料、新工艺在沥青路面... 详细信息

文章介绍了广西防城港某市政道路工程的基本情况,分析了路面结构早期损坏的特点和原因,沥青道路路面裂缝的形成、危害、种类及产生原因,提出了对裂缝进行预防和处理的措施,并介绍了路面材料养护技术的应用,对新材料、新工艺在沥青路面裂缝修复中的应用研究具有一定的参考价值。

关键词：沥青混凝土路面裂缝预防措施

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Effects of aggregate size distribution and carbon nanotubes on the mechanical properties of cemented gangue backfill samples under true triaxial compression

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International Journal of Minerals,Metallurgy and Materials 2025年第2期32卷 311-324页

作者： Qian Yin Fan Wen Zhigang Tao Hai Pu Tianci Deng Yaoyao meng Qingbin meng Hongwen Jing Bo meng Jiangyu Wu State Key Laboratory of Intelligent Construction and Healthy Operation and Maintenance of Deep Underground Engineering China University of Mining and TechnologyXuzhou 221116China State Key Laboratory of Mining Response and Disaster Prevention and Control in Deep Coal Mines Anhui University of Science and TechnologyHuainan 232001China State Key Laboratory for Geomechanics&Deep Underground Engineering China University of Mining and Technology(Beijing)Beijing 100083China Key Laboratory of Xinjiang Coal Resources Green Mining Ministry of EducationXinjiang Institute of EngineeringUrumqi 830023China

The mechanical behavior of cemented gangue backfill materials(CGBMs)is closely related to particle size distribution(PSD)of aggregates and properties of cementitious ***,the true triaxial compression tests,CT scanning,SEM,and EDS tests were conducted on cemented gangue backfill samples(CGBSs)with various carbon nanotube concentrations(P_(CNT))that satisfied fractal theory for the PSD of *** mechanical properties,energy dissipations,and failure mechanisms of the CGBSs under true triaxial compression were systematically *** results indicate that appropriate carbon nanotubes(CNTs)effectively enhance the mechanical properties and energy dissipations of CGBSs through micropore filling and microcrack bridging,and the optimal effect appears at P_(CNT)of 0.08wt%.Taking PSD fractal dimension(D)of 2.500 as an example,compared to that of CGBS without CNT,the peak strength(σ_(p)),axial peak strain(ε_(1,p)),elastic strain energy(Ue),and dissipated energy(U_(d))increased by 12.76%,29.60%,19.05%,and90.39%,***,excessive CNTs can reduce the mechanical properties of CGBSs due to CNT agglomeration,manifesting a decrease inρ_(p),ε_(1,p),and the volumetric strain increment(Δε_(v))when P_(CNT)increases from 0.08wt%to 0.12wt%.Moreover,the addition of CNTs improved the integrity of CGBS after macroscopic failure,and crack extension in CGBSs appeared in two modes:detour and pass through the ***σ_(p)and U_(d)firstly increase and then decrease with increasing D,and porosity shows the opposite ***ε_(1,p)andΔε_(v)are negatively correlated with D,and CGBS with D=2.150 has the maximum deformation parameters(ε_(1,p)=0.05079,Δε_(v)=0.01990)due to the frictional slip effect caused by coarse *** increasing D,the failure modes of CGBSs are sequentially manifested as oblique shear failure,"Y-shaped"shear failure,and conjugate shear failure.

关键词： cemented gangue backfill materials particle size distribution true triaxial compression test carbon nanotubes mechanical properties failure modes

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多聚腺苷二磷酸核糖聚合酶及其抑制剂与炎症治疗的研究进展

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国际药学研究杂志 2013年第1期40卷 85-89页

作者：肖梦良王晓奎郑志兵李松孟艳秋军事医学科学院毒物药物研究所药物合成研究室北京100850 沈阳化工大学制药工程教研室沈阳110142

多聚腺苷二磷酸核糖聚合酶(PARP)是近年发现的治疗炎性疾病的一个新靶点,其过度活化能在基因水平调节炎症相关因子,如核因子-κB、诱导型一氧化氮合酶、激活蛋白-1、热休克蛋白1等的表达,从而导致细胞变性坏死,引起炎症反应。因此PARP... 详细信息

多聚腺苷二磷酸核糖聚合酶(PARP)是近年发现的治疗炎性疾病的一个新靶点,其过度活化能在基因水平调节炎症相关因子,如核因子-κB、诱导型一氧化氮合酶、激活蛋白-1、热休克蛋白1等的表达,从而导致细胞变性坏死,引起炎症反应。因此PARP被认为是炎性疾病发病的诱因之一,抑制PARP的活性将为治疗炎性疾病带来新的希望。本文就PARP的蛋白结构和功能及其在炎症中的作用机制,以及PARP抑制剂在炎性疾病治疗中的应用研究作一综述。

关键词：多聚腺苷二磷酸核糖聚合酶,抑制剂炎症

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Biomass materials for zinc-based sustainable and green energy storage devices:Strategy and mechanism

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Nano Research 2025年第1期18卷 294-314页

作者： xiaotong Yang xiaoxin Nie Chenke Tang Yiyang xiao Qiongguang Li Du Yuan meng Yao College of Materials Science and Engineering Changsha University of Science and TechnologyChangsha 410004China College of Materials Science and Engineering Sichuan UniversityChengdu 610065China Anhui Province International Research Center on Advanced Building Materials School of Materials and Chemical EngineeringAnhui Jianzhu UniversityHefei 230601China

As next-generation rechargeable alternatives,zincbased energy storage devices(ZESs)are being intensely explored due to their merits of abundant resource,low cost,safety and environmental ***,ZESs face a succession of critical challenges on pursuing advancing performance,including the stability and kinetics of cathode,stability and transport of zinc electrolyte,reversibility and deep utilization of metallic Zn ***,possessing unique molecular structures with abundant functionals groups,motivates the interdisciplinary field emerging from biomass and aqueous rechargeable *** its high compatibility with ZES design,we here summarize the application of biomass materials in ZESs from the aspects of cathode,electrolyte,membrane/separator and Zn anode,with their corresponding operational mechanisms and attractive functionalities from polymeric ***,the outlooks and perspectives are provided,regarding current challenges and future *** anticipate our minireview paves way on exploring the roles of biomass in aqueous rechargeable batteries.

关键词： zinc biomass materials skeleton/host coating solid-electrolyte interphase(SEI)

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