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Correlation of Microstructure Feature with Impact Fracture Behavior in a TMCP Processed High Strength Low Alloy Construction Steel

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Acta Metallurgica Sinica(English Letters) 2022年第4期35卷 527-536页

作者： Wen-Ting zhu Jun-Jun Cui Zhen-Ye Chen Yang Zhao li-Qing Chen State Key Laboratory of Rolling and Automation Northeastern UniversityShenyang 110819China Key Laboratory of Nuclear Materials and Safety Assessment Institute of Metal ResearchChinese Academy of SciencesShenyang 110016China User Technology Department Technology Research Institute of HBISShijiazhuang 050000China School of Materials Science and Engineering Northeastern UniversityShenyang 110819China

The present article aims at elucidating the effect of thermo-mechanical controlled processing(TMCP), especially the finish cooling temperature, on microstructure and mechanical properties of high strength low alloy steels for developing superior low temperature toughness construction steel. The microstructural features were characterized by scanning electron microscope equipped with electron backscatter diffraction, and the mechanical behaviors in terms of tensile properties and impact toughness were analyzed in correlation with microstructural evolution. The results showed that the lower finish cooling temperature could lead to a considerable increase in impact toughness for this steel. A mixed microstructure was obtained by TMCP at lower finish cooling temperature, which contained much fine lath-like bainite with dot-shaped M/A constituent and less granular bainite and bainite ferrite. In this case, this steel possesses yield and ultimate tensile strengths of ~ 885 MPa and 1089 MPa, respectively, and a total elongation of ~ 15.3%, while it has a lower yield ratio of ~ 0.81. The superior impact toughness of ~ 89 J at-20 °C was obtained, and this was resulted from the multi-phase microstructure including grain refinement, preferred grain boundaries misorientation, fine lath-like bainite with dot-shaped M/A constituent.

关键词： High strength low alloy steel Thermo-mechanical controlled processing(TMCP) Finish cooling temperature Microstructure Mechanical properties Impact toughness

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Protein Phosphatase 2C of Toxoplasma Gondii Interacts with Human SSRP1 and Negatively Regulates Cell Apoptosis

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Biomedical and Environmental Sciences 2014年第11期27卷 883-893页

作者： GAO Xue Juan FENG Jun Xia zhu Sen liU xiao Hui TARDIEUX Isabelle liU Lang Xia Key Laboratory of Functional Protein Research of Guangdong Higher Education Institutes Institute of Life and Health EngineeringJinan University Institut Cochin Université DescartesTeam FRM ‘Barriers and Pathogens’22 Rue Méchain

Objective The protozoan Toxoplasma gondii expresses large amounts of a 37 kDa Type 2C serine-threonine phosphatase,the so-called TgPP2 C which has been suggested to contribute to parasite growth *** expression in mammalian cells also indicated that the enzyme could regulate growth and *** this study,we aimed to investigate the interaction of TgPP2 C with human SSRP1（structure-specific recognition protein 1） and the effects of TgPP2 C on cell *** The yeast two hybrid system,His-tag pull-down and co-immunoprecipitation assays were used to confirm the interaction of TgPP2 C with SSRP1 and determine the binding domain on *** evaluation of cell apoptosis was performed using cleaved caspase-3 antibody and Annexin-V/PI kit combined with flow *** We identified human SSRP1 as an interacting partner of TgPP2 *** C-terminal region of SSRP1 including the amino acids 471 to 538 was specifically mapped as the region responsible for interaction with TgPP2 *** overexpression of TgPP2 C down-regulated cell apoptosis and negatively regulated apoptosis induced by DRB,casein kinase II（CKII） inhibitor,through enhanced interaction with *** TgPP2 C may be a parasitic factor capable of promoting cell survival through interaction with the host protein SSRP1,thereby creating a favorable environment for parasite growth.

关键词： Apoptosis SSRP1 TgPP2C Toxoplasma gondii

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Diastereoselective Construction of α-Fluoroalkyl Cycloalkanols via Radical Alkylation of α-Fluoroalkyl Ketones

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Chinese Journal of Chemistry 2023年第23期41卷 3275-3280页

作者： Yi liu Ji li Yulu Zhou Hanliang Zheng Zhenlu Shen Gangguo zhu Key Laboratory of the Ministry of Education for Advanced Catalysis Materials Department of ChemistryZhejiang Normal University688 Yingbin RoadJinhuaZhejiang321004 China College of Chemical Engineering Zhejiang University of TechnologyHangzhouZhejiang310032 China

α-Fluoroalkyl (Rf) alcohols are privileged motifs in drugs and pharmaceutically active *** such,it is highly desirable to develop efficient methods for assembling these ***,a visible-light-induced cascade radical cyclization of alkenyl fluoroalkyl ketones is developed,producing a variety of decorate α-Rf cycloalkanols in promising yields with up to >20 : 1 dr selectivity.A radical chain mechanism involving an intramolecular radical addition to the α-Rf carbonyl group and a subsequent intermolecular hydrogen atom transfer (HAT) has been *** functional theory (DFT) calculations indicate that a fluorine effect contributes to the radical addition to carbonyls by lowering the π* (C=O) orbital energy of CORf and energy barrier of the HAT between alkoxy radicals and THF,which may be valuable for controllable transformations of fluorinated molecules.

关键词： Radical reactions Cyclization Alkylation α-Fluoroalkyl ketones Fluorine effect Alcohols

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Stochastic properties of tumor growth with coupling between non-Gaussian and Gaussian noise terms

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Chinese Physics B 2012年第9期21卷 120-127页

作者：蒋莉莉罗晓琴吴丹朱士群 School of Physical Science and Technology Soochow University

Dynamical behavior of a tumor-growth model with coupling between non-Gaussian and Gaussian noise terms is investigated. The departure from the Gaussian noise can not only reduce the probability of tumor cells in the active state, induce the minimum of the average tumor-cell population to move toward a smaller non-Gaussian noise, but also decrease the mean first-passage time. The increase of white-noise intensity can increase the tumor-cell population and shorten the mean first-passage time, while the coupling strength between noise terms has opposite effects, and the noise correlation time has a very small effect.

关键词： tumor growth stochastic property non-Gaussian noise Gaussian noise

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Ferroptosis contributes to JEV-induced neuronal damage and neuroinflammation

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Virologica Sinica 2024年第1期39卷 144-155页

作者： Wenjing zhu Qi li Yong Yin Huanchun Chen Youhui Si Bibo zhu Shengbo Cao Zikai Zhao Jing Ye National Key Laboratory of Agricultural Microbiology Huazhong Agricultural UniversityWuhan430070China Frontiers Science Center for Animal Breeding and Sustainable Production Huazhong Agricultural UniversityWuhan430070China The Cooperative Innovation Center for Sustainable Pig Production Huazhong Agricultural UniversityWuhan430070China Hubei Hongshan Laboratory Wuhan430070China

Ferroptosis is a newly discovered prototype of programmed cell death (PCD) driven by iron-dependent phospholipid peroxidation accumulation, and it has been linked to numerous organ injuries and degenerative pathologies. Although studies have shown that a variety of cell death processes contribute to JEV-induced neuroinflammation and neuronal injury, there is currently limited research on the specific involvement of ferroptosis. In this study, we explored the neuronal ferroptosis induced by JEV infection in vitro and in vivo. Our results indicated that JEV infection induces neuronal ferroptosis through inhibiting the function of the antioxidant system mediated by glutathione (GSH)/glutathione peroxidase 4 (GPX4), as well as by promoting lipid peroxidation mediated by yes-associated protein 1 (YAP1)/long-chain acyl-CoA synthetase 4 (ACSL4). Further analyses revealed that JEV E and prM proteins function as agonists, inducing ferroptosis. Moreover, we found that treatment with a ferroptosis inhibitor in JEV-infected mice reduces the viral titers and inflammation in the mouse brains, ultimately improving the survival rate of infected mice. In conclusion, our study unveils a critical role of ferroptosis in the pathogenesis of JEV, providing new ideas for the prevention and treatment of viral encephalitis.

关键词： Japanese encephalitisvirus(JEV) Ferroptosis Neuron lipid peroxidation Inflammatory response

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Alkyl chain modulation of asymmetric hexacyclic fused acceptor synergistically with wide bandgap third component for high efficiency ternary organic solar cells

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International Journal of Minerals,Metallurgy and Materials 2024年第7期31卷 1713-1719页

作者： Shufang li Huilan Guan Can zhu Chaoyuan Sun Qingya Wei Jun Yuan Yingping Zou College of Chemistry and Chemical Engineering Central South UniversityChangsha 410083China Beijing National Laboratory for Molecular Sciences CAS Key Laboratory of Organic SolidsInstitute of ChemistryChinese Academy of SciencesBeijing 100190China Institute of Carbon Neutrality and New Energy School of Electronics and InformationHangzhou Dianzi UniversityHangzhou 310018China

Herein,two asymmetric hexacyclic fused small molecule acceptors(SMAs),namely BP4F-HU and BP4F-UU,were *** elongated outside chains in the BP4F-UU molecule played a crucial role in optimizing the morphology of blend film,thereby improving charge mobility and reducing energy loss within the corresponding ***,the PM6:BP4F-UU device exhibited a higher open-circuit voltage(V_(oc))of 0.878 V compared to the PM6:BP4F-HU device with a V_(oc)of 0.863 ***,a new wide bandgap SMA named BTP-TA was designed and synthesized as the third component to the PM6:BP4F-UU host binary devices,which showed an ideal complementary absorption spectrum in PM6:BP4F-UU *** addition,BTP-TA can achieve efficient intermolecular energy transfer to BP4F-UU by fluorescence resonance energy transfer(FRET)pathway,due to the good overlap between the photoluminescence(PL)spectrum of BTP-TA and the absorption region of ***,ternary devices with 15wt%BTP-TA exhibits broader photon utilization,optimal blend morphology,and reduced charge recombination compared to the corresponding binary ***,PM6:BP4F-UU:BTP-TA ternary device achieved an optimal power conversion efficiency(PCE)of 17.83%with simultaneously increased V_(oc)of 0.905 V,short-circuit current density(J_(sc))of 26.14 mA/cm^(2),and fill factor(FF)of 75.38%.

关键词： asymmetric hexacyclic acceptor outside chain wide bandgap acceptor ternary organic solar cells

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Optimization of Gas Production from Hydrate-Bearing Sediments with Fluctuation Characteristics

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Journal of Ocean University of China 2024年第3期23卷 618-632页

作者： li Yaobin XU Tianfu XIN Xin YU Han YUAN Yilong zhu Huixing Key Laboratory of Groundwater Resources and Environment Ministry of EducationJilin UniversityChangchun 130021China Jilin Provincial Key Laboratory of Water Resources and Environment Jilin UniversityChangchun 130021China

As an important source of low-carbon,clean fossil energy,natural gas hydrate plays an important role in improving the global energy consumption *** the hydrate industry in the South China Sea is important to achieving‘carbon peak and carbon neutrality’goals as soon as ***-water areas subjected to the action of long-term stress and tectonic movement have developed complex and volatile terrains,and as such,the morphologies of hydrate-bearing sediments(HBSs)fluctuate *** key to numerically simulating HBS morphologies is the establishment of the conceptual model,which represents the objective and real description of the actual geological ***,current numerical simulation models have characterized HBSs into horizontal strata without considering the fluctuation *** representing the HBS as a horizontal element reduces simulation ***,the commonly used horizontal HBS model and a model considering the HBS’s fluctuation characteristics with the data of the SH2 site in the Shenhu Sea area were first constructed in this ***,their production behaviors were compared,and the huge impact of the fluctuation characteristics on HBS production was *** this basis,the key parameters affecting the depressurization production of the fluctuating HBSs were studied and *** research results show that the fluctuation characteristics have an obvious influence on the hydrate production of HBSs by affecting their temperatures and pressure distributions,as well as the transmission of the pressure drop and methane gas ***,the results show that the gas productivity of fluctuating HBSs was about 5%less than that of horizontal *** optimizing the depressurization amplitude,well length,and layout location of vertical wells,the productivity of fluctuating HBSs increased by about 56.6%.

关键词： natural gas hydrate numerical simulation fluctuation characteristics depressurization production production well optimization

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Effect of CaF_(2) and CaO/Al_(2)O_(3) on viscosity and structure of TiO_(2)-bearing slag for electroslag remelting

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Journal of Iron and Steel Research International 2021年第12期28卷 1541-1550页

作者： Jian-tao Ju Kang-shuai Yang Zhi-hong zhu Yue Gu li-zhong Chang School of Metallurgical Engineering Xi’an University of Architecture and TechnologyXi’an710055ShaanxiChina Shaanxi Engineering Research Center of Metallurgical Xi’an710055ShaanxiChina School of Metallurgy Engineering Anhui University of TechnologyMa’anshan243002AnhuiChina

The relationship between the viscosity and structure of CaF_(2)-CaO-Al_(2)O_(3)-MgO-TiO_(2)slag with different CaF_(2)contents and CaO/Al_(2)O_(3)ratios was studied using the rotating cylinder method,Fourier transform infrared spectroscopy,and Raman *** activity coefficients of CaF_(2)and the CaO/Al_(2)O_(3)ratio were determined to understand the correlation between viscosity and structure of the *** results suggest that the slag viscosity reduces gradually with an increase in CaF_(2)content from 14.1 to 28.1 wt.%or CaO/Al_(2)O_(3)ratio from 0.9 to 1.5,and correspondingly apparent activation energy for viscous flow *** addition of CaF_(2)does not change the structure of the molten slag;however,the relaxation effect of the anionic species and the hindrance effect of the cationic species are promoted by substituting part of the non-bridging oxygens(NBO)with F−ions from CaF_(2),which is attributed to the formation of NBO-Ca^(2+)-F−and NBO-Ca^(2+)-NBO,***,as the CaO/Al_(2)O_(3)ratio increases,some of the Q4 units in the aluminate structure are depolymerized into Q2 units,so that the relative strength of the Al-O-Al linkage decreases,and the relative fraction of Ti2O64−chains increases,whereas that of O-Ti-O chains decreases slightly,resulting in depolymerization on the slag ***,the effect of the CaO/Al_(2)O_(3)ratio on the structure was greater than that of CaF_(2)because of the greater depolymerization *** variation in the activity can indirectly explain the relationship between the viscosity and structure of the aluminate structural units based on thermodynamic analysis.

关键词： Viscosity TiO_(2)-bearing slag Fourier transform infrared spectroscopy Raman spectrum Thermodynamic

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Laser ablation mechanism and performance of glass fiber-reinforced phenolic composites:An experimental study and dual-scale modelling

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Chinese Journal of Aeronautics 2024年第8期37卷 470-485页

作者： Ran BI Pengfei SHEN Longyu zhu Zhengzheng MA Chuyang LUO Yongfeng li lijian PAN Shanghai Key Laboratory of lightweight Composite Donghua UniversityShanghai 201620China Shanghai High Performance Fibers and Composites Center(Province-Ministry Joint) Center for Civil Aviation CompositesDonghua UniversityShanghai 201620China AVIC Composite Corporation Ltd Beijing 101300China

Both experimental and simulation approaches were employed to investigate the laser ablation mechanism and performances of Glass Fiber Reinforced Phenolic Composites(GFRP).During the ablation process,the difference in thermal conductivities of the glass fibers and the resin matrix as well as their discrepant physical and chemical reactions form a conical ablation *** formation of a residual carbon layer effectively mitigates the ablation rate in the thickness direction.A higher power density results in a faster ablation rate,while a longer irradiation time leads to a larger ablation pit *** account for the variation in thermal conductivity between the fiber and resin,a macro-mesoscale model was developed to differentiate the matrix from the fiber *** element analysis revealed that laser irradiation leads to phenolic decomposition,glass fiber melting vaporization,and residual carbon skeleton *** dual-scale model exhibits precise prediction capabilities concerning the laser ablation process of GFRP,and its accuracy is confirmed through the comparison of simulation and experimental results for the GFRP laser ablation *** model provides a feasible method for performance evaluation and lifetime prediction of GFRP subjected to continuous wave laser irradiation.

关键词： Polymer-matrix composites Continuous-wave laser Microstructural analysis Ablation mechanism Finite element method

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RNN-Based Demand Awareness in Smart library Using CRFID

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China Communications 2020年第5期17卷 284-294页

作者： Ruiqin Bai Jumin Zhao Dengao li xiaoyu Lv Qiang Wang Biaokai zhu College of Information and Computer Taiyuan University of TechnologyJinzhong 030600China College of Data Science Taiyuan University of TechnologyJinzhong 030600China Technology Research Center of Spatial Information Network Engineering of Shanxi Jinzhong 030600China

To provide more intelligence service in the smart library, we need to better perceive the reader’s preferences. In addition to perceiving online records based on readers’ search history and borrowing records, advanced information technologies give us more chance to perceive the behavior of readers in the actual reading process and further discover the need for reading. In this paper, we use CRFID and RNN deep learning network to recognize book motions in the reading process, so as to judge readers’ need degree for the book, which can provide a basis for library book purchases and readers personalized service. In order to improve the recognition accuracy, we use the RSS as well as acceleration magnitude gathered from CRFID as the input data for RNN, and design a new encoding scheme. We trained and tested the deep learning network using real-world data, recorded during actual reading in our lab environment which mimics a typical reading room, from the experimental results, we conclude that our approach is feasible to recognize different reading phase to perceiving the needs of the readers.

关键词： demand awareness detection of phases CRFID RNN smart library

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