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Interleukin-10 and chronic liver disease

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World Journal of Gastroenterology 2006年第11期12卷 1681-1685页

作者： Li-juan Zhang xiao-Zhong wang Department of Gastroenterology Union Hospital of Fujian Medical University Fuzhou 350001 Fujian Province China

Interleukin （IL）-10 is an important immunoregulatory cytokine produced by many cell populations. Numerous investigations suggest that IL-10 plays a major role in chronic liver diseases. IL-10 gene polymorphisms are possibly assodated with liver disease susceptibility or se-verity. Recombinant human IL-10 has been produced and is currently tested in clinical trials. These trials may give new insights into the immunobiology of IL-10 and suggest that the IL-10/IL-10 receptor system may become a new therapeutic target.

关键词： Interleukin (IL)-10 Cytokine Chronic liver diseases Polymorphisms

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XRF法测定绿泥石岩型滑石中10元素分析

化学工程师 2017年第8期31卷 24-26页

作者：肖娟王洪桂和莉蔚志毅青海省有色矿勘院测试中心青海西宁810007

绿泥石岩型滑石主要成分是斜绿泥石,因镁和铝的含量相对较高,测试过程中干扰较大,为消除基体效应所带来的影响,故采用混合熔剂高温熔融制样和X射线荧光光谱法同时测定绿泥石岩型滑石中的多元素分析,本法不仅可以测定地质样品绿泥石岩型... 详细信息

绿泥石岩型滑石主要成分是斜绿泥石,因镁和铝的含量相对较高,测试过程中干扰较大,为消除基体效应所带来的影响,故采用混合熔剂高温熔融制样和X射线荧光光谱法同时测定绿泥石岩型滑石中的多元素分析,本法不仅可以测定地质样品绿泥石岩型滑石中多元素,而且测试周期短,实验流程简单,样品用料少,可测定不同地质样品中的化探样品和化学样品,经实验测试结果的比对,结果准确,可靠,而且测量结果的精密度好,准确度高,数据和化学法的结果基本一致,但比化学法成本低,流程短,适用于绿泥石岩型滑石中各主要元素的分析。

关键词：绿泥石岩型滑石基体效应高温熔融 X射线荧光光谱仪

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新西兰麻组培技术初探

福建林业科技 2016年第3期43卷 178-182页

作者：毕玮吴涛耿云芬原晓龙王娟云南省林业科学院云南昆明650201 国家林业局重点开放性实验室云南珍稀濒特森林植物保护和繁育实验室云南省森林植物培育与开发利用重点实验室中国-新西兰森林植物培育与开发利用联合实验室云南昆明650201

以新西兰麻种子为外植体材料,进行组培试验,建立离体培养技术体系。结果表明,以75%酒精消毒60 s,再用0.1%Hg Cl2消毒5 min的效果最好;丛生芽增殖的适宜培养基为MS+6-BA 2 mg·L^(-1)+KT 0.4 mg·L^(-1);诱导不定根的适宜培养基为MS+IBA ... 详细信息

以新西兰麻种子为外植体材料,进行组培试验,建立离体培养技术体系。结果表明,以75%酒精消毒60 s,再用0.1%Hg Cl2消毒5 min的效果最好;丛生芽增殖的适宜培养基为MS+6-BA 2 mg·L^(-1)+KT 0.4 mg·L^(-1);诱导不定根的适宜培养基为MS+IBA 1 mg·L^(-1)+NAA 0.5 mg·L^(-1);生根组培苗炼苗移栽30 d后,成活率达84%以上。

关键词：新西兰麻组织培养消毒方法培养基

Static load test and load transfer mechanism study of squeezed branch and plate pile in collapsible loess foundation

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2007年第7期8卷 1110-1117页

作者： GAO xiao-juan wang Jin-chang ZHU Xiang-rong College of Civil Engineering and Architecture Zhejiang University Hangzhou 310027 China Institute of Architecture Engineering Henan University of Science and Technology Luoyang 471003 China Ningbo Institute of Technology Zhejiang University Ningbo 315005 China

As a special geological phenomenon, the character of collapsible loess foundation is collapsible when penetrated by water. This character leads to the soil losing load bearing capacity largely and may lead to foundation failure. Pile is a popular foundation used in collapsible loess. The squeezed branch and plate pile is a new type of pile developed in recent years and has not be used in a project before. In this paper three squeezed branch and plate piles are tested in collapsible loess after immersion processing. The results may be used for reference in similar construction project, and to provide theoretical references for de- signing of the squeezed branch and plate piles in engineering practice.

关键词： Collapsible loess foundation Squeezed branch and plate pile Immersion processing Full-scale static load test

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兔慢性高眼压模型的眼部表现

国际眼科杂志 2007年第4期7卷 948-950页

作者：杨新光于敬妮王晓娟中国陕西省西安市第四医院眼科 710004

目的:观察慢性高眼压状态对兔眼及其视盘的影响。方法:新西兰白兔,10眼前房内抽出0.2mL房水后注射0.2mL复方卡波姆溶液,使眼压慢性升高,10眼为对照组。每天测眼压1次,4wk后,眼底照相,并取出视盘周围视网膜及球后视神经制片,镜下观察。结... 详细信息

目的:观察慢性高眼压状态对兔眼及其视盘的影响。方法:新西兰白兔,10眼前房内抽出0.2mL房水后注射0.2mL复方卡波姆溶液,使眼压慢性升高,10眼为对照组。每天测眼压1次,4wk后,眼底照相,并取出视盘周围视网膜及球后视神经制片,镜下观察。结果:对照组眼前节、视盘、筛板等正常;高眼压组眼部有明显的变化,视盘加深、筛板处形态显著凹陷。结论:高眼压模型眼部改变明显,尤其是视盘筛板更接近临床慢性青光眼的改变。

关键词：慢性高眼压视盘筛板

Adaptive dynamic programming for linear impulse systems

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Journal of Zhejiang University-Science C(Computers and Electronics) 2014年第1期15卷 43-50页

作者： xiao-hua wang juan-juan YU Yao HUANG Hua wang Zhong-hua MIAO School of Mechatronics Engineering and Automation Shanghai University Shanghai Key Laboratory of Power Station Automation Technology Shanghai University

We investigate the optimization of linear impulse systems with the reinforcement learning based adaptive dynamic programming(ADP)*** linear impulse systems,the optimal objective function is shown to be a quadric form of the pre-impulse *** ADP method provides solutions that iteratively converge to the optimal objective *** an initial guess of the pre-impulse objective function is selected as a quadratic form of the pre-impulse states,the objective function iteratively converges to the optimal one through *** direct use of the quadratic objective function of the states within the ADP method is theoretically possible,the numerical singularity problem may occur due to the matrix inversion therein when the system dimensionality increases.A neural network based ADP method can circumvent this problem.A neural network with polynomial activation functions is selected to approximate the pre-impulse objective function and trained iteratively using the ADP method to achieve optimal *** a successful training,optimal impulse control can be *** are presented for illustrative purposes.

关键词： Adaptive dynamic programming(ADP) Impulse system Optimal control Neural network

Impact of two types of La Nia on boreal autumn rainfall around Southeast Asia and Australia

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Atmospheric and Oceanic Science Letters 2018年第1期11卷 1-6页

作者： FENG juan wang xiao-Cong Center for Monsoon System Research Institute of Atmospheric PhysicsChinese Academy of SciencesBeijingChina State Key Laboratory of Numerical Modeling for Atmospheric Sciences and Geophysical Fluid Dynamics Institute of Atmospheric PhysicsChinese Academy of SciencesBeijingChina

The distinct influences of eastern Pacific （EP） and central Pacific （CP） La Nina on rainfall anomalies over Southeast Asia and Australia in boreal autumn （September to November） are explored in this study. Composite results reveal that CP La Nina gives rise to significant and severe flooding over Southeast Asia and Australia, whereas EP La Nina fails to exert any evident impacts on rainfall over this region. This difference can be attributed to the distinct features of cooling sea surface temperature anomalies （SSTAs） between EP and CP La Nina. With a more westward location and stronger intensity of the negative SSTAs during CP La Nina autumn, the highest and lowest SLP anomalies are substantially enhanced and shift westwards too, further causing intense easterly winds over the western Pacific and westerly anomalies over the Indian Ocean driven by this SLP gradient. Subsequently, robust low-level convergence and high-level divergence is observed over the Maritime Continent and Australia, resulting in significant above-normal rainfall anomalies in those regions. In contrast, weak and eastern Pacific-confined cooling SSTAs during EP La Nina produce correspondingly weak low-level convergence over the Maritime Continent conditions that make it hard for significant rainfall anomalies to arise.

关键词： EP La Nina CP La Nina Southeast Asian rainfall Australian rainfall

Hydrogen sulfide enhances adult neurogenesis in a mouse model of Parkinson's disease

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Neural Regeneration Research 2021年第7期16卷 1353-1358页

作者： Min wang juan-juan Tang Lin-xiao wang Jun Yu Li Zhang Chen Qiao Department of Clinical Pharmacy The Affiliated Hospital of Jiangsu UniversityJiangsu UniversityZhenjiangJiangsu ProvinceChina Department of Geriatrics Affiliated Brain Hospital of Nanjing Medical UniversityNanjingJiangsu ProvinceChina School of Medicine&Holistic Integrative Medicine Nanjing University of Chinese MedicineNanjingJiangsu ProvinceChina Laboratory of Neurological Diseases Department of Neurologythe Affiliated Changzhou No.2 People’s Hospital of Nanjing Medical UniversityChangzhouJiangsu ProvinceChina Laboratory of Reproductive Medicine The Affiliated Hospital of Jiangsu UniversityJiangsu UniversityZhenjiangJiangsu ProvinceChina

Hydrogen sulfide(H_2S) is regarded to be a protectant against diseases of the central nervous system and cardiovascular ***, the mechanism by which H_2S elicits neuroprotective effects in the progression of Parkinson's disease(PD) remains *** investigate the role of H_2S in delaying the pathological process of PD, we used the most common sodium hydrosulfide(Na HS) as an H_2S donor and established a mouse model of PD induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine/probenecid(MPTP/p) in the present *** results show that H_2S reduced neuronal loss during the progression of ***, we found that H_2S exhibited protective effects on dopaminergic ***, H_2S also increased the proliferation of neural stem cells in the subventricular ***, we evaluated whether the neuroprotective effects of H_2S on dopaminergic neurons in PD are dependent on adult nerve regeneration by treating primary adult neural stem cells cultured ex vivo with *** results show that H_2S could prevent nerve injury induced by 1-methyl-4-phenylpyridine, promote the growth of neurospheres, and promote neurogenesis by regulating Akt/glycogen synthase kinase-3β/β-catenin pathways in adult neural stem *** findings confirm that H_2S can increase neurogenesis in an adult mouse model of PD by regulating the Akt/glycogen synthase kinase-3β/β-catenin signaling *** study was approved by the Animal Care and Use Committee of Nanjing Medical University, China(IACUC Approval No.1601153-3).

关键词： factor hydrogen sulfide medical gas neural stem cells neurogenesis neuroprotection Parkinson's disease pathways

Role of nutrition in diabetes mellitus and infections

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World Journal of Clinical Cases 2025年第3期13卷 1-8页

作者： Xue-Lu Yu Li-Yun Zhou xiao Huang Xin-Yue Li Ming-Ke wang Ji-Shun Yang Naval Medical Center of PLA Naval Medical UniversityShanghai 200052China

In this editorial,we have commented on the article that has been published in the recent issue of World Journal of Clinical *** authors have described a case of unilateral thyroid cyst and have opined that the acute onset of infection may be linked to diabetes mellitus(DM).We have focused on the role of nutrition in the association between DM and *** with DM are at a high risk of infection,which could also be attributed to nutrition-related *** interventions for patients with diabetes are mainly based on a low-calorie diet,which can be achieved by adhering to a low-carbohydrate ***,dietary fiber supplementation is recommended to maintain the diversity of the gut ***,high-quality protein can prevent the increased risk of infection due to *** of vitamins C,vitamins A,vitamins D,and folic acid improves blood sugar control and facilitates immune *** deficiencies augment the risk of infection,but the relationship with diabetes is mostly U-shaped and a good intake should be maintained.

关键词： Diabetes mellitus Infection Macronutrients Vitamins Minerals