检索结果-南通市图书馆

Infliximab is effective in the treatment of ulcerative colitis with dermatomyositis:A case report

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2020年第46期26卷 7425-7435页

作者： Bin-Bin Huang Li-Chun Han Geng-Feng Liu xiao-dan lv Guang-Li Gu Shi-Quan Li Lan Chen Hui-Qin Wang Ling-Ling Zhan xiao-Ping lv Department of Gastroenterology The First Affiliated Hospital of Guangxi Medical UniversityNanning 530021Guangxi Zhuang Autonomous RegionChina Department of Clinical Laboratory The First Affiliated Hospital of Guangxi Medical UniversityNanning 530021Guangxi Zhuang Autonomous RegionChina

BACKGROUND Joint,skin,oral cavity,and eye lesions are the most common extraintestinal manifestations of ulcerative colitis that can occur before or after its *** cases of ulcerative colitis with dermatomyositis(DM)are *** this study,we report a rare case of ulcerative colitis with DM that was effectively treated with *** SUMMARY The patient was a 57-year-old female with a 2-year history of *** patient was admitted to hospital with abdominal pain,diarrhea,and blood in stool lasting for more than 2 *** revealed multiple erosions and ulcers in the entire colon and *** sections showed chronic inflammatory cell infiltration,especially neutrophil infiltration,in the colonic mucosa;therefore,the patient was diagnosed with ulcerative *** of 5-aminosalicylic acid was added to her treatment based on the original treatment for DM,but its effect was *** patient’s discomfort was relieved after infliximab *** Infliximab can improve DM in the treatment of ulcerative *** need to raise awareness about patients with inflammatory bowel disease who have rare extraintestinal manifestations.

关键词： Ulcerative colitis Dermatomyositis Extraintestinal manifestation Infliximab Mesalazine Case report

A Generalized MSST Algorithm for Counting Points of Elliptic Curves over F_(p)^(n)

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Systems Science & Complexity 2024年第4期37卷 1738-1754页

作者： LI xiao lv Chang PAN Zhizhong Key Laboratory of Cyberspace Security Defense Institute of Information EngineeringChinese Academy of SciencesBeijing 100085China School of Cyber Security University of Chinese Academy of SciencesBeijing 100085China Huawei Technologies Co. Ltd.Shenzhen 518129China

Elliptic curve cryptography is an important part of nowaday's public key *** points of elliptic curves over finite fields is of great significance to the selection of safety *** present,there are many p-adic algorithms,such as SST algorithm,generalized AGM algorithm,Kedlaya algorithm,etc.,which can deal with the situation of finite fields of small *** this paper,the authors generalize the MSST algorithm of characteristic 2 to general fields of odd characteristic,and propose the generalized MSST *** generalized MSST algorithm is achieved by combining the advantages of the SST algorithm and the generalized AGM *** the time complexity of the multiplication of two n-bit numbers is denoted as O((n)^(μ)),then the time complexity of the generalized MSST algorithm is O(n^(2μ+1/1+μ)),which is the same as the improved SST *** practical experiments,the running time of the generalized MSST algorithm is less than that of the improved SST algorithm.

关键词： Elliptic curve generalized AGM algorithm generalized MSST algorithm SST algorithm

Global outreach and networking promotion to accelerate tropical diseases elimination

在线全文

学校读者我要写书评

暂无评论

贫困所致传染病(英文) 2024年第3期13卷 1-5页

作者： lv Shan Zhou xiao-Nong National Institute of Parasitic Diseases at Chinese Center for Disease Control and Prevention (Chinese Center for Tropical Diseases Research) NHC Key Laboratory of Parasite and Vector Biology WHO Collaborating Centre for Tropical Diseases Shanghai People’s Republic of China School of Global Health Chinese Center for Tropical Diseases Research Shanghai Jiao Tong University School of Medicine Shanghai People’s Republic of China Institute of One Health Shanghai Jiao Tong University Shanghai People’s Republic of China Hainan Center for Tropical Diseases Research (Hainan Subcenter of Chinese Center for Tropical Diseases Research) Haikou People’s Republic of China

Cooperation and networking are powerful tools in the combating against tropical diseases. Cooperation on a global scale is essential due to the transboundary nature of tropical diseases. Networking plays a pivotal role in facilitating such cooperation. Both cooperation and networking can foster innovation in disease control programmes. Collaborative research can lead to the development of new drugs and vaccines, while shared surveillance data can enable the early detection and control of disease epidemics. Therefore, consensus of cooperation and networking has been reached during the 7th Symposium on Surveillance-Response Systems Leading to Tropical Diseases Elimination, which reflected in the two documents, i.e.,Consensus for Transboundary Tropical Diseases Control, andAction Consensus of the Network of WHO Collaborating Centres Related to NTDs. These documents will improve the efforts in the fighting against tropical diseases through collective actions to achieve the United Nations’ Sustainable Development Goals (SDGs).

关键词： Tropical diseases Cooperation Networking Elimination Sustainable development goals

同方期刊数据库

Equilibrium Reinsurance Strategy and Mean Residual Life Function

在线全文

学校读者我要写书评

暂无评论

Acta Mathematicae Applicatae Sinica 2024年第3期40卷 758-777页

作者： dan-ping LI lv CHEN Lin-yi QIAN Wei WANG School of Statistics Key Laboratory of Advanced Theory and Application in Statistics and Data Science-MOEEast China Normal UniversityShanghai 200062China Academy of Statistics and Interdisciplinary Sciences Key Laboratory of Advanced Theory and Application in Statistics and Data Science-MOEEast China Normal UniversityShanghai 200062China School of Mathematics and Statistics Ningbo UniversityNingbo 315211China

In this paper,we analyze the relationship between the equilibrium reinsurance strategy and the tail of the distribution of the *** Mean Residual Life(MRL)has a close relationship with the tail of the distribution,we consider two classes of risk distributions,Decreasing Mean Residual Life(DMRL)and Increasing Mean Residual Life(IMRL)distributions,which can be used to classify light-tailed and heavy-tailed distributions,*** assume that the underlying risk process is modelled by the classical CramérLundberg model *** the mean-variance criterion,by solving the extended Hamilton-Jacobi-Bellman equation,we derive the equilibrium reinsurance strategy for the insurer and the reinsurer under DMRL and IMRL,***,we analyze how to choose the reinsurance premium to make the insurer and the reinsurer agree with the same reinsurance *** find that under the case of DMRL,if the distribution and the risk aversions satisfy certain conditions,the insurer and the reinsurer can adopt a reinsurance premium to agree on a reinsurance strategy,and under the case of IMRL,the insurer and the reinsurer can only agree with each other that the insurer do not purchase the reinsurance.

关键词： mean residual life excess-of-loss reinsurance insurer reinsurer stochastic control

同方期刊数据库

Area Operators on Bergman Spaces

在线全文

学校读者我要写书评

暂无评论

Acta Mathematica Sinica,English Series 2024年第5期40卷 1161-1176页

作者： xiao Fen lv Jordi PAU Mao Fa WANG Department of Mathematics Huzhou UniversityHuzhou 313000P.R.China Departament de Matemàtiques i Informàtica Universitat de Barcelona08007 BarcelonaCataloniaSpain School of Mathematics and Statistics Wuhan UniversityWuhan 430072P.R.China

We completely characterize the boundedness of area operators from the Bergman spaces A_(α)^(p)(Bn)to the Lebesgue spaces L^(q)(S_(n))for all 0 详细信息

We completely characterize the boundedness of area operators from the Bergman spaces A_(α)^(p)(Bn)to the Lebesgue spaces L^(q)(S_(n))for all 0lve the cases left open there and extend the results to n-complex dimension.

关键词： Area operator Bergman space tent space area formula

Odorant receptor orthologues from moths display conserved responses to cis-jasmone

在线全文

学校读者我要写书评

暂无评论

Insect Science 2024年第4期31卷 1107-1120页

作者： xiao-Qing Hou Zhongqiang Jia dan-dan Zhang Guirong Wang Shenzhen Branch Guangdong Laboratory for Lingnan Modern AgricultureSynthetic Biology Laboratory of the Ministry of Agriculture and Rural AffairsAgricultural Genomics Institute at ShenzhenChinese Academy of Agricultural SciencesShenzhenGuangdong ProvinceChina State Key Laboratory for Biology of Plant Diseases and Insect Pests Institute of Plant ProtectionChinese Academy of Agricultural SciencesBeijingChina Department of Biology Lund UniversityLundSweden

In insects,the odorant receptor(OR)multigene family evolves by the birth-and-death evolutionary model,according to which the OR repertoire of each species has undergone specific gene gains and losses depending on their chemical environment,resulting in taxon-specific OR lineage radiations with different sizes in the phylogenetic *** the general divergence in the gene family across different insect orders,the ORs in moths seem to be genetically conserved across species,clustered into 23 major clades containing multiple orthologous groups with single-copy gene from each *** hypothesized that ORs in these orthologous groups are tuned to ecologically important compounds and functionally ***-Jasmone is one of the compounds that not only primes the plant defense of neighboring receiver plants,but also functions as a behavior regulator to various *** test our hypothesis,using Xenopus oocyte recordings,we functionally assayed the orthologues of BmorOR56,which has been characterized as a specific receptor for *** results showed highly conserved response specificity of the BmorOR56 orthologues,with all receptors within this group exclusively responding to *** is supported by the dN/dS analysis,showing that strong purifying selection is acting on this ***,molecular docking showed that the ligand binding pockets of BmorOR56 orthologues to cis-jasmone are *** together,our results suggest the high conservation of OR for ecologically important compounds across Heterocera.

关键词： cis-jasmone evolutionary conservation functional characterization molec-ular docking moths purifying selection

Energy consumption optimization for edge computing-supported cellular networks based on optimal transport theory

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Science China(Information Sciences) 2024年第2期67卷 201-218页

作者： Xiangyu lv xiaohu GE Yi ZHONG Qiang LI Yong xiao School of Electronic Information and Communications Huazhong University of Science and Technology

With advancements in mobile communication technologies, there have been multiple user device(UD) connections to cellular networks. Because of changes in the spatial distribution of UDs and application requirements, the traditional offloading mechanism based on the nearest distance will result in heavy loads for some base stations(BSs). Because there is a high-order relationship between the energy consumption of the BS processing tasks and the number of computing tasks, the traditional offloading mechanism will result in high energy consumption, and UD’s offloading decision must be dynamically adjusted. The offloading decision of UDs is optimized based on detailed information about various parameters associated with a network from the standpoint of distribution. This information includes details regarding the spatial distribution of UDs,application requirements, and the offloading period of computing tasks. Based on optimal transport theory,an energy consumption optimization algorithm is suggested to lower the total amount of energy consumed by the offloading process of UDs’ computing tasks by reasonably planning the offloading BSs of the UDs in the networks. The simulation results show that the proposed offloading mechanism based on energy consumption optimization reduces the total energy consumption of the offloading process by 28.09% when compared to the traditional offloading mechanism, and the traffic managed by each BS is balanced.

关键词： optimal transport theory edge computing energy consumption reduction dynamic voltage frequency scaling

A micro-crosslinked amphoteric hydrophobic association copolymer as high temperature-and salt-resistance fluid loss reducer for water-based drilling fluids

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Petroleum Science 2024年第3期21卷 1980-1991页

作者： Jian Li Yu-Xi Ji xiao-xiao Ni Kai-He lv Xian-Bin Huang Jin-Sheng Sun School of Petroleum Engineering China University of Petroleum(East China)Qingdao266580ShandongChina Key Laboratory of Unconventional Oil&Gas Development China University of Petroleum(East China)Qingdao26650ShandongChina Inspection and Testing Center of Huabei Oil Field Company PetroChinaRenqiu062552HebeiChina Drilling Fluid Research Institute CNPC Engineering Technology R&D Company LimitedBeijing102206China

During ultradeep oil and gas drilling,fluid loss reducers are highly important for water-based drilling fluids,while preparing high temperature-and salt-resistance fluid loss reducers with excellent rheology and filtration performance remains a ***,a micro-crosslinked amphoteric hydrophobic association copolymer(i.e.,DADC)was synthesized using N,N-dimethyl acrylamide,diallyl dimethyl ammonium chloride,2-acrylamido-2-methylpropane sulfonic acid,hydrophobic monomer,and pentaerythritol triallyl ether *** to the synergistic effects of hydrogen bonds,electrostatic interaction,hydrophobic association,and micro-crosslinking,the DADC copolymer exhibited outstanding temperature-and *** rheological experiments have shown that the DADC copolymer had excellent shear dilution performance and a certain degree of salt-responsive viscosity-increasing *** DADC copolymer could effectively adsorb on the surface of bentonite particles through electrostatic interaction and hydrogen bonds,which bring more negative charge to the bentonite,thus improving the hydration and dispersion of bentonite particles as well as the colloidal stability of the drilling ***,the drilling fluids constructed based on the DADC copolymer exhibited satisfactory rheological and filtration properties(FLHTHP=12 m L)after aging at high temperatures(up to200℃)and high salinity(saturated salt)***,this work provided new insights into designing and fabricating high-performance drilling fluid treatment agents,demonstrating good potential applications in deep and ultradeep drilling engineering.

关键词： Fluid loss reducer Temperature-and salt-resistance Hydrophobic association Amphoteric Micro-crosslinking

RARRES2 regulates lipid metabolic reprogramming to mediate the development of brain metastasis in triple negative breast cancer

在线全文

学校读者我要写书评

暂无评论

Military Medical Research 2024年第1期11卷 34-49页

作者： Yi-Qun Li Fang-Zhou Sun Chun-xiao Li Hong-Nan Mo Yan-Tong Zhou dan lv Jing-Tong Zhai Hai-Li Qian Fei Ma Department of Medical Oncology National Cancer Center/National Clinical Research Center for Cancer/Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100021China State Key Laboratory of Molecular Oncology National Cancer Center/National Clinical Research Center for Cancer/Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100021China

Background Triple negative breast cancer(TNBC),the most aggressive subtype of breast cancer,is characterized by a high incidence of brain metastasis(BrM)and a poor *** the most lethal form of breast cancer,BrM remains a major clinical challenge due to its rising incidence and lack of effective treatment *** evidence suggested a potential role of lipid metabolic reprogramming in breast cancer brain metastasis(BCBrM),but the underlying mechanisms are far from being fully *** Through analysis of BCBrM transcriptome data from mice and patients,and immunohistochemical validation on patient tissues,we identified and verified the specific down-regulation of retinoic acid receptor responder 2(RARRES2),a multifunctional adipokine and chemokine,in BrM of *** investigated the effect of aberrant RARRES2 expression of BrM in both in vitro and in vivo *** signaling pathway components were evaluated using multi-omics *** were performed to elucidate the regulation of lipid metabolic reprogramming of *** We found that downregulation of RARRES2 is specifically associated with BCBrM,and that RARRES2 deficiency promoted BCBrM through lipid metabolic ***,reduced expression of RARRES2 in brain metastatic potential TNBC cells resulted in increased levels of glycerophospholipid and decreased levels of triacylglycerols by regulating phosphatase and tensin homologue(PTEN)-mammalian target of rapamycin(mTOR)-sterol regulatory element-binding protein 1(SREBP1)signaling pathway to facilitate the survival of breast cancer cells in the unique brain *** Our work uncovers an essential role of RARRES2 in linking lipid metabolic reprogramming and the development of ***2-dependent metabolic functions may serve as potential biomarkers or therapeutic targets for BCBrM.

关键词： RARRES2 Lipid metabolic reprogramming Brain metastasis(BrM) Breast cancer