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Risk factors and care of early surgical site infection after primary posterior lumbar interbody fusion

Frontiers of Nursing 2023年第2期10卷 203-211页

作者： xiao-lin zuo Yan Wen Orthopedic trauma Luohe Central Hospital(The First Affiliated Hospital of Luohe Medical College)LuoheHenan 462000China Department of Nursing Luohe Central Hospital(The First Affiliated Hospital of Luohe Medical College)LuoheHenan 462000China

Objectives:To explore the risk factors and nursing measures of early surgical site infection(SSI)after posterior lumbar interbody fusion(PLIF).Methods:A total of 468 patients who received PLIF in our hospital from January 2017 to June 2020 were enrolled into this *** to the occurrence of early SSI,the patients were divided into two groups,and the general data were analyzed by univariate *** logistic regression analysis was conducted with the dichotomous variable of whether early SSI occurred and other factors as independent variables to identify the risk factors of early SSI and put forward targeted prevention and nursing ***:Among 468 patients with PLIF,18 patients developed early SSI(3.85%).The proportion of female,age,diabetes mellitus and urinary tract infection(UTI),operation segment,operation time,post-operative drainage volume,and drainage time were significantly higher than those in the uninfected group,with statistical significance(P0.05).Logistic regression analysis showed that preoperative diabetes mellitus(OR=2.109,P=0.012)/UTI(OR=1.526,P=0.035),prolonged drainage time(OR=1.639,P=0.029)were risk factors for early ***(OR=0.736,P=0.027)and albumin level(OR=0.526,P=0.004)were protective factors in reducing early ***:Women,preoperative diabetes/UTI,hypoproteinemia,and prolonged drainage time are risk factors for early SSI after *** effective preventive measures should be taken in combination with targeted nursing intervention to reduce the risk of early SSI.

关键词： incisional infection nursing measures posterior lumbar interbody fusion risk factors multivariate regression analysis

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Monitoring glaciers in the Chenab basin with SBAS InSAR technology

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Journal of Mountain Science 2022年第9期19卷 2622-2633页

作者： DING Yue-kai LIU Rui FAN Yi-fei ZHOU ling-xiang JI Qin ZHANG Hong xiao zuo-lin The Key Laboratory of GIS Application Research School of Geography and TourismChongqing Normal UniversityChongqing 401331China

The Chenab basin is located in northwest India and eastern *** in Chenab basin,as local freshwater resources,are very important to the regional ecological environment and *** the same time,SBAS InSAR can monitor the deformation of the ground for a long time,the monitoring accuracy can reach mm level,and can obtain the time series change of deformation,whcih provides a new idea and method for glacier *** this study,the deformation from SBAS InSAR was combined with glacial area data to study the glacial changes in Chenab ***-1 and Landsat series images were used to obtain the deformation and change in the area of glaciers by SBAS InSAR and the semi-automated *** results showed that glaciers in the Chenab basin retreated rapidly,especially in the past ten *** glacier area decreased by 88.05 km^(2)in 1990~2000 and 118.86 km^(2) in 2000~2010,and the glacier area decreased by 236.01 km^(2) in 2010~2020,which was the largest rate of change of 9.49%.Moreover,glacial deformation decreased in 2020,and the deformation rate ranged from-146.3mm/a to 119.52 mm/*** glaciers had deformation rates between-50 mm/a and 50 mm/*** by precipitation and temperature,glacial deformation in the Chenab basin started to change in August,the maximum accumulation was 6,828.43mm,and the minimum ablation was-20,656.41 mm.

关键词： Glacier retreat SBAS-InSAR Climate change Chenab basin

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Characteristics and changes of the Himalayas glacial area in China during 1990-2015

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Journal of Mountain Science 2022年第7期19卷 1961-1973页

作者： SHI Shu-xian XING Li DING Yue-kai DONG Jun LIU Rui JI Qin xiao zuo-lin HUANG Xun The Key Laboratory of GIS Application Research School of Geography and TourismChongqing Normal UniversityChongqing401331China Key Laboratory of Geographic Information Science(Ministry of Education) East China Normal UniversityShanghai2002412China

In recent decades,the continuously changed glaciers in the Himalayas not only affected process of atmospheric flow and water cycle in the plateau but also increased the frequency of secondary disasters,such as ice collapse and outburst ***,the monitoring of Himalayas glacial change is of great significance in the aspects of climate change and disaster prevention and *** Himalayas glacier outlines in China were extracted by ratio threshold and visual interpretation based on the Landsat TM/ETM+/OLI data and glacier catalogue *** on the ASTER GDEM data,the distribution and change characteristics at different altitudes were studied,and the surface moraine was identified to study the influence of glacial area *** addition,Glaciers were divided into marine and continental glaciers in this study,and the distribution and changes of the two types of glaciers were ***,a comprehensive analysis of a long time series was *** results showed that:(1)From 1990 to 2015,the glaciers in the study area showed an overall trend of melting;the annual melting speed gradually accelerated from 0.48%/a to 0.75%/*** total melting glacial area was 828.16 km,and the melting rate of the glaciers in the western section was the highest,at 0.63%.(2)The total area of continental glaciers was larger than that of marine glaciers,and its reduction was relatively larger,too.(3)The average size of debris-covered glaciers was 10 times that of debris-free glaciers,but their rate of change(8.1%)was 1/2 of that of debrisfree glaciers(17.8%).(4)The number of glaciers gradually decreased as the size of glaciers *** glaciers with grades of>50 km,0.5~1 km,and 1~2 kmhad large change rates,which were 20.1%,19.1%,and 18.5%,*** summary,the Himalayas glaciers in China were melting at an accelerated rate and their numbers were gradually decreasing from 1990 to *** location,type,elevation,size and debris cover of a glacier are all i

关键词： Himalayas Glacial area Remote sensing Shrinkage and expansion area Debris-covered glaciers

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Metabolomic Analysis in Saliva and Different Brain Regions of Older Mice with Postoperative Delirium Behaviors

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Biomedical and Environmental Sciences 2024年第2期37卷 133-145页

作者： LIU xiao CAO Ying lin xiao Wan GAO Dan Yang MIAO Hui Hui LI Tian zuo Department of Anesthesiology Beijing Shijitan HospitalCapital Medical UniversityBeijing 100038China

Objective Postoperative delirium(POD)has become a critical challenge with severe consequences and increased incidences as the global population ***,the underlying mechanism is yet *** study aimed to explore the changes in metabolites in three specific brain regions and saliva of older mice with postoperative delirium behavior and to identify potential non-invasive *** Eighteen-month-old male C57/BL6 mice were randomly assigned to the anesthesia/surgery or control *** tests were conducted 24 h before surgery and 6,9,and 24 h after *** C3(C3)and S100 calcium-binding protein B protein(S100beta)levels were measured in the hippocampus,and a metabolomics analysis was performed on saliva,hippocampus,cortex,and amygdala *** In total,43,33,38,and 14 differential metabolites were detected in the saliva,hippocampus,cortex,and amygdala,respectively.“Pyruvate”“alpha-linolenic acid”and“2-oleoyl-1-palmitoy-snglycero-3-phosphocholine”are enriched in one common pathway and may be potential non-invasive biomarkers for *** changes were observed in the three brain regions,with the upregulation of 1-methylhistidine and downregulation of *** Dysfunctions in energy metabolism,oxidative stress,and neurotransmitter dysregulation are implicated in the development of *** identification of changes in the level of salivary metabolite biomarkers could aid in the development of noninvasive diagnostic methods for POD.

关键词： Metabolomic Postoperative delirium(POD) Mechanism Biological marker

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Study on the optimal incident proton energy of ^(7)Li(p,n)^(7)Be neutron source for boron neutron capture therapy

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Nuclear Science and Techniques 2024年第3期35卷 170-180页

作者： Yi-Nan Zhu zuo-Kang lin Hai-Yan Yu Ye Dai Zhi-Min Dai xiao-Han Yu Shanghai Institute of Applied Physics Chinese Academy of SciencesShanghai 201800China University of Chinese Academy of Science Beijing 100049China

Boron neutron capture therapy(BNCT)is recognized as a precise binary targeted radiotherapy technique that effectively eliminates tumors through the^(10)B(n,α)^(7)Li nuclear *** various neutron sources,accelerator-based sources have emerged as particularly promising for BNCT ***^(7)Li(p,n)^(7)Be reaction is highly regarded as a potential neutron source for BNCT,owing to its low threshold energy for the reaction,significant neutron yield,appropriate average neutron energy,and additional *** study utilized Monte Carlo simulations to model the physical interactions within a lithium target subjected to proton bombardment,including neutron moderation by an MgF_(2)moderator and subsequent BNCT dose analysis using a Snyder head *** study focused on calculating the yields of epithermal neutrons for various incident proton energies,finding an optimal energy at 2.7 ***,the Snyder head phantom was employed in dose simulations to validate the effectiveness of this specific incident energy when utilizing a^(7)Li(p,n)^(7)Be neutron source for BNCT purposes.

关键词： Boron neutron capture therapy ^(7)Li(p,n)7Be neutron source Incident proton energy Monte Carlo simulation

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Impact wear properties of dissimilar joints between bainitic frogs and pearlite rails

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Journal of Iron and Steel Research(International) 2024年第1期31卷 275-287页

作者： Pin-yong Zeng Chun-guang zuo xiao-yu Zhang Wei Li Tribology Research Institute Southwest Jiaotong UniversityChengdu610031SichuanChina

The impact wear behavior and damage mechanism of dissimilar welded joints between U26Mn frog and U75 V rail before and after normalizing treatment were studied by cyclic impact *** experiment indicated that the impact wear volume of the joints increased with the increasing number of impact *** main wear mechanisms include pitting wear,mild fatigue wear,delamination wear,and fatigue wear,and plastic deformation was the primary impact wear *** them,fatigue wear had the greatest influence on wear volume,while other wear mechanisms had limited *** impact wear resistance of the base material was better than that of the heat-affected *** treatment was beneficial to improving the impact wear resistance of welded joints owing to its effect to promote pearlite recovery,grain refinement,and uniform distribution of *** martensite generated in the rail welded joints aggravated the impact wear damage to the materials,which should be avoided.

关键词： Dissimilar welded joint Impact wear Bainitic steel Damage mechanism Wear rate

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Amplification effect of intra-seasonal variability of soil moisture on heat extremes over Eurasia

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Advances in Climate Change Research 2024年第1期15卷 1-8页

作者： Yi-Nuo WANG Zhi-Yan zuo Liang QIAO Kai-Wen ZHANG Mei-Yu CHANG Dong xiao Zou-Xing lin Huan WANG Department of Atmospheric and Oceanic Sciences Institute of Atmospheric SciencesFudan UniversityShanghai 200438China CMA-FDU Joint Laboratory of Marine Meteorology Shanghai 200438China Key Laboratory of Cites Mitigation and Adaptation to Climate Change in Shanghai China Meteorological AdministrationShanghai 200030China Collaborative Innovation Centeron Forecast and Evaluation of Meteorological Disasters Nanjing University of Information Science and TechnologyNanjing 211800China Shanghai Frontiers Science Center of Atmosphere-Ocean Interaction Shanghai 200123China College of Geography and Resources Science Sichuan Normal UniversityChengdu 610101China National Observations and Research Station for Wetland Ecosystems of the Yangtze Estuary Shanghai 202183China Chinese Academy of Meteorological Sciences China Meteorological AdministrationBeijing 100081China

Drying soil has been conducive to a high frequency of extreme high-temperature events over many regions worldwide in recent ***,changes in the intraseasonal variability of soil moisture can also influence the likelihood of extremely high *** previous investigators have examined the association between extremely high temperatures and large-scale atmospheric circulation variability,the role of land-atmosphere coupling dominated by soil moisture variability in extremely high temperatures,particularly over the Eurasian continent,is not well *** this study,on the basis of the Land Surface,Snow,and Soil Moisture Model Intercomparison Project,we found that land-atmosphere feedback amplified the variability of soil moisture in most regions of Eurasia during summer from 1980 to *** amplification of soil moisture variability is closely correlated with more intensive intraseasonal variability of surface air temperature and more frequent occurrences of extreme high-temperature events,particularly in Europe,Siberia,Northeast Asia,and the Indochina *** correlation implies that increasing the intraseasonal variability of soil moisture results in a high likelihood of heat extremes during summer in most parts of Eurasia except Asian desert *** the intraseasonal timescale,the land-atmosphere coupling increases the variability of surface sensible heat flux and net long-wave radiation heating the atmosphere by intensifying the soil moisture variability,thus amplifying the variability of surface air temperature and enhancing the extreme high-temperature *** finding demonstrates the importance of changes in intraseasonal soil moisture variability for the increasing likelihood of heat extremes in summer.

关键词： Soil moisture Intraseasonal variability Land-atmosphere coupling Heat extremes

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Switchable Multicomponent Cyclization Reactions to Access Fluoroalkylated Dihydropyrimidines and Pyrimidines under Solvent-Free Conditions

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Chinese Journal of Chemistry 2024年第12期42卷 1394-1398页

作者： Wanqing zuo Zhizhen Zhu Yu Cheng lingling zuo xiao Geng Zhifang Li Lei Wang College of Material Chemistry and Chemical Engineering Key Laboratory of Organosilicon Chemistry and Material TechnologyMinistryof EducationHangzhouNormal UniversityHangzhouZhejiang311121China Advanced Research Institute and School of Pharmaceutical Sciences Taizhou UniversityJiaojiangZhejiang 318000China state Key Laboratory of Organometallic Chemistry Shanghai Institute of Organic ChemistryChinese Academy of SciencesShanghai200032China

Comprehensive Summary The development of switchable solvent-free multicomponent reactions to build high-value-added products is an important demand for organic ***,we detailed the successful implementation of a switchable strategy for the construction of diverse 4-fluoroalkyl-1,4-dihydropyrimidines and 4-fluoroalkyl-pyrimidines via a solvent/additive-free[3+2+1]annulation,starting from readily available enamines,trifluoroacetaldehyde hydrate or 1-ethoxy-2,2-difluoroethanol and amidines *** reaction conforms to the concept of green synthesis,and provides a new avenue to access valuable fluorinated heterocycles.

关键词： Fluorine chemistry Multicomponent reactions Environmental chemistry Heterocycles Enaminones Amidines

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A care bundle for pressure ulcer treatment in intensive care units

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International Journal of Nursing Sciences 2015年第4期2卷 340-347页

作者： xiao-lin zuo Fan-Jie Meng Graduate School Tianjin University of Traditional Chinese MedicineTianjin 300193China School of Nursing Tianjin University of Traditional Chinese MedicineTianjin 300193China

Pressure ulcers(PUs)are localized injuries of the skin or underlying tissue caused by prolonged pressure,exposure to shear forces or *** represent a major concern for hospitalized patients and the health professionals responsible for their *** care init(ICU)patients are at high risk of PU development,and the development of PUs can significantly extend the length of time a patient must remain in the *** with PUs experience significantly increased morbidity,mortality and financial burden.A significant amount of evidence has accumulated indicating that PU prevention is an essential component of patient ***,standardized guidelines and protocols for PU prevention in ICUs have not been universally *** review aims to describe and analyze an optimized PU prevention care bundle based on the best available evidence and existing national *** distilled the available information into five main topics important for PU prevention:Risk Assessment,Skin Assessment,Support Surfaces,Nutrition and *** larger scale studies are needed to clinically verify the effectiveness of the care bundle.

关键词： Pressure ulcer Care bundle Intensive care unit

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Wireless electrical stimulation generated by piezoelectric nanomaterial promotes the dental pulp regeneration via regulating mitochondrial Ca^(2+)/PKA signaling pathway

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Journal of Materials Science & Technology 2024年第1期168卷 24-34页

作者： Jianmao Zheng Jiyuan zuo Cairong xiao Qining Guo xiaobin Fu Chengyun Ning Peng Yu Guangdong Provincial Key Laboratory of Stomatology Hospital of StomatologySun Yat-Sen UniversityGuangzhou 510080China School of Materials Science and Engineering National Engineering Research Center for Tissue Restoration and ReconstructionSouth China University of TechnologyGuangzhou 510641China

The induction of dental pulp stem cells(DPSCs)into odontogenic differentiation is a cutting-edge method of dental pulp regeneration ***,it remains a challenge to develop biomaterials and ther-apies that can induce odontogenic ***,we propose a wireless electrical stimulation strat-egy to induce DPSCs odontogenic differentiation via K_(0.5)Na_(0.5)NbO_(3)piezoelectric nanoparticles(KNN)and polarized KNN(PKNN),which can be endocytosed by *** vitro,several odontogenic differentiation indexes were also increased in DPSCs treated with KNN and PKNN,and the increase was more obvious in the PKNN *** wireless electrical field promoted mitochondrial calcium concentration via mitochondrial calcium unidirectional transporter(MCU),increased the production of adenosine triphos-phate(ATP),and induced odontogenic differentiation through the activation of the cAMP-PKA signaling *** vivo,dental pulp-like tissue was induced by electrical stimulation wirelessly with KNN and PKNN,which was more clinically friendly compared with the wired device,and the induction was more obvious in the PKNN group consistent with in vitro *** conclusion,this work demonstrates the potential of PKNN as an effective stimulus that can induce odontogenic differentiation of DPSCs and be applied to dental pulp regeneration treatment.

关键词： Piezoelectric nanoparticles Dental pulp stem cells Odontogenic differentiation

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