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Curve Shortening Flow in Arbitrary Dimensional Euclidian Space

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Acta Mathematica Sinica,English Series 2005年第4期21卷 715-722页

作者： Yun Yan YANG xiao xiang jiao School of Mathematical Sciences Peking University Beijing 100871 P. R. China Graduate School Chinese Academy of Sciences P. R. China

In this paper, curve shortening flow in Euclidian space R^n（n≥3） is studied, and S. Altschuler＇s results about flow for space curves are generalized. We prove that the curve shortening flow converges to a straight line in infinite time if the initial curve is a ramp. We also prove the planar phenomenon when the curve shortening flow blows up.

关键词： Curve shortening flow Singularity formation Blow up

Sulfuretin exerts diversified functions in the processing of amyloid precursor protein

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Genes & Diseases 2021年第6期8卷 867-881页

作者： Jian Chen Biao Luo Bi-Rou Zhong Kun-Yi Li Qi-Xin Wen Li Song xiao-jiao xiang Gui-Feng Zhou Li-Tian Hu xiao-Juan Deng Yuan-Lin Ma Guo-Jun Chen Department of Neurology The First Affiliated Hospital of Chongqing Medical UniversityChongqing Key Laboratory of Neurology1 Youyi RoadChongqing400016PR China Department of Neurology Nanchong Central HospitalThe Second Clinical College of North Sichuan Medical CollegeNanchongSichuan Province637000PR China

Sulfuretin is a flavonoid that protects cell from damage induced by reactive oxygen species and *** this study,we investigated the role of sulfuretin in the processing of amyloid precursor protein(APP),in association with the two catalytic enzymes the a-secretase a disintegrin and metalloproteinase(ADAM10),and the beta-site APP cleaving enzyme 1(BACE1)that play important roles in the generation of β amyloid protein(Aβ)in Alzheimer’s disease(AD).We found that sulfuretin increased the levels of the immature but not the mature form of ADAM10 *** enhanced ADAM10 transcription by sulfuretin was mediated by the nucleotides444 to300 in the promoter region,and was attenuated by silencing or mutation of transcription factor retinoid X receptor(RXR)and by GW6471,a specific inhibitor of peroxisome proliferator-activated receptor α(PPAR-α).We further found that sulfuretin preferentially increased protein levels of the immature form of APP(im-APP)but significantly reduced those of BACE1,sAPPβ and β-CTF,whereas Ab1-42 levels were slightly ***,the effect of sulfuretin on BACE1 and im-APP was selectively attenuated by the translation inhibitor cycloheximide and by lysosomal inhibitor chloroquine,*** together,(1)RXR/PPAR-α signaling was involved in sulfuretin-mediated ADAM10 transcription.(2)Alteration of Aβ protein level by sulfuretin was not consistent with that of ADAM10 and BACE1 protein levels,but was consistent with the elevated level of im-APP protein,suggesting that im-APP,an isoform mainly localized to trans-Golgi network,plays an important role in Ab generation.

关键词： Ab ADAM10 BACE1 Immature APP RXR/PPAR-a Sulfuretin Trans-Golgi network

Observation of acoustic hybrid topological phases induced by the p-d orbital interactions

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Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 132-139页

作者： xiao xiang Feng Gao Yu-Gui Peng Peng Wu Zong-Lin Li Xue-Feng Zhu School of Physics and Innovation Institute Huazhong University of Science and Technology

In spinless systems,growing attention has recently been attracted to synthetic gauge fields,which redefine the fundamental crystal symmetries by utilizing the projective algebraic ***,synthetic gauge fields have been commonly investigated in single orbital systems,and explorations on hybrid orbitals remain elusive in ***,we report the experimental observation of hybrid topological phases induced by hybrid synthetic gauge flux,which is formed by the interaction between p and d orbitals embedded in acoustic *** breaking the translation symmetries of Lxand/or Ly,we unambiguously demonstrate the first-order M?bius edge states and higher-order corner *** work establishes a platform for seeking exotic topological phases induced by hybrid-orbitals interactions and initializing the framework of hybrid-orbitalsrelated topological *** applications can be anticipated in scenarios such as high-quality sensing and robust wave trapping due to the stepwise energy distribution of the hybrid topological phase.

关键词： topological insulator synthetic gauge field projective symmetry corner states

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一种新的考虑应力敏感影响的三项式产能方程

天然气地球科学 2014年第5期25卷 767-770页

作者：肖香姣毕研鹏王小培高杰常志强张建业中国石油塔里木油田分公司勘探开发研究院新疆库尔勒841000 西南石油大学"油气藏地质及开发工程"国家重点实验室四川成都610500

低渗透气藏存在较强的应力敏感性,对大量岩石实验数据回归研究表明,幂函数渗透率应力敏感性经验方程相关性相对较好,但是利用该关系式来研究低渗透气藏气井产能的报道还较少。利用幂函数渗透率应力敏感性经验公式,综合考虑渗透率应力敏... 详细信息

低渗透气藏存在较强的应力敏感性,对大量岩石实验数据回归研究表明,幂函数渗透率应力敏感性经验方程相关性相对较好,但是利用该关系式来研究低渗透气藏气井产能的报道还较少。利用幂函数渗透率应力敏感性经验公式,综合考虑渗透率应力敏感效应、启动压力梯度、紊流效应和表皮系数,建立了一个新的适用于低渗透异常高压气井的三项式产能方程。不同参数组合情况下的气井流入动态曲线对比研究结果表明,应力敏感性、启动压力梯度和紊流效应对低渗透气藏气井产能的影响较大,在产能评价研究时必须予以考虑。

关键词：应力敏感启动压力梯度紊流效应产能方程流入动态曲线

Laparoscopic liver resection utilizing the ventral avascular area of the inferior vena cava:A retrospective cohort study

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World Journal of Gastroenterology 2025年第1期31卷 42-57页

作者： Kun Huang Zhu Chen Heng xiao Hai-Yang Hu Xing-Yu Chen Cheng-You Du xiang Lan Department of Hepatobiliary Surgery The First Affiliated Hospital of Chongqing Medical UniversityChongqing 400000China Department of General Surgery Mianyang Hospital of Traditional Chinese MedicineMianyang 621000Sichuan ProvinceChina

BACKGROUND Laparoscopic liver resection(LLR)can be challenging due to the difficulty of establishing a retrohepatic tunnel under *** the third hepatic hilum before parenchymal transection often leads to significant liver mobilization,tumor compression,and bleeding from the short hepatic veins(SHVs).This study introduces a novel technique utilizing the ventral avascular area of the inferior vena cava(IVC),allowing SHVs to be addressed after parenchymal transection,thereby reducing surgical complexity and improving outcomes in in situ *** To introduce and evaluate a novel LLR technique using the ventral avascular area of the IVC and compare its short-term outcomes with conventional *** The clinical cohort data of patients with pathologically confirmed hepatocellular carcinoma or intrahepatic cholangiocarcinoma who underwent conventional LLR and novel LLR between July 2021 and July 2023 at the First Affiliated Hospital of Chongqing Medical University were retrospectively *** novel LLR,we initially separated the caudate lobe from the IVC using dissecting forceps along the ventral avascular area of the ***,we transected the parenchyma of the left and right caudate lobes from the caudal side to the cephalic side using the avascular area as a ***,we addressed the SHVs and finally dissected the root of the right hepatic vein or left hepatic *** short-term postoperative outcomes and oncological results of the two approaches were evaluated and *** A total of 256 patients were included,with 150(58.59%)undergoing conventional LLR and 106(41.41%)undergoing novel *** novel technique resulted in significantly larger tumor resections(6.47±2.96 cm vs 4.01±2.33 cm,P<0.001),shorter operative times(199.57±60.37 minutes vs 262.33±83.90 minutes,P<0.001),less intraoperative blood loss(206.92±37.09 mL vs 363.34±131.27 mL,P<0.001),and greater resection volume(345.11±31.40 mL vs 264.38±31.98 mL,P<0.001)comp

关键词： Laparoscopic liver resection Inferior vena cava Retrohepatic tunnel Short hepatic veins Complex liver tumors Intraoperative bleeding control

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应用分子标记技术改良京作1号的稻瘟病抗性

植物遗传资源学报 2016年第4期17卷 773-780页

作者：向小娇张建郑天清徐建龙中国农业科学院作物科学研究所北京100081 中国农业科学院深圳农业基因组研究所广东深圳518120

稻瘟病是危害水稻产量的重要生物胁迫之一。实践证明,解决这一问题的最有效方法是培育具广谱、持久稻瘟病抗性的品种并推广种植。本研究以优质、高产、感稻瘟病的京作1号为轮回亲本,与稻瘟病抗性基因Pi9、Pigm和pi21的供体材料进行杂交... 详细信息

稻瘟病是危害水稻产量的重要生物胁迫之一。实践证明,解决这一问题的最有效方法是培育具广谱、持久稻瘟病抗性的品种并推广种植。本研究以优质、高产、感稻瘟病的京作1号为轮回亲本,与稻瘟病抗性基因Pi9、Pigm和pi21的供体材料进行杂交、回交和复交,结合分子标记辅助选择和农艺性状筛选,培育不同的单基因导入系和聚合系。苗期人工接种多个稻瘟病菌的结果显示,Pi9抗性改良系的抗性频率达到100%,Pigm抗性改良系平均为90%,均极显著高于轮回亲本京作1号的抗性频率,且农艺性状与京作1号基本一致。pi21抗性改良系的抗性水平与京作1号没有明显差异,单株产量极显著低于京作1号。与轮回亲本相比,Pi9和pi21聚合系的抗性频率极显著提高,达到93.33%,但单株产量明显降低。研究结果证实了Pi9和Pigm基因在大幅度提高抗瘟性的同时对主要农艺性状影响小,都具有较大的育种利用价值。基因pi21抗谱较窄,抗性不强,且可能存在对产量的负效应,不宜单独用来改良水稻品种的稻瘟病抗性,需要与抗性强的主基因聚合,通过多次回交和自交打破该基因与产量的不利连锁累赘。

关键词：品种改良稻瘟病抗性分子标记辅助选择抗谱抗性水平

利用水平井提高凝析气藏原油采收率(为庆祝塔里木油田石油会战20周年而作)

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新疆石油地质 2009年第2期30卷 238-240页

作者：昌伦杰肖香姣卞万江林娜中国石油塔里木油田分公司勘探开发研究院新疆库尔勒841000

采用水平井可以有效提高凝析气藏原油的采收率;利用水平井开发井网,先期开采底油、适时上返采气,可在不影响天然气采收率的前提下有效提高原油采收率;对英买7凝析气藏而言,将水平井部署在油气界面之上1～2m处、水平段长度300m、采油速... 详细信息

采用水平井可以有效提高凝析气藏原油的采收率;利用水平井开发井网,先期开采底油、适时上返采气,可在不影响天然气采收率的前提下有效提高原油采收率;对英买7凝析气藏而言,将水平井部署在油气界面之上1～2m处、水平段长度300m、采油速度控制在2.5%以下进行开发,既不影响天然气采收率,又可以提高原油采收率。

关键词：凝析气藏底油水平井提高采收率

塔里木盆地克拉2气田断裂地质力学活动性对水侵的影响

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天然气地球科学 2017年第11期28卷 1735-1744页

作者：江同文张辉王海应尹国庆肖香姣中国石油塔里木油田分公司新疆库尔勒841000

中国陆相最大天然气田——克拉2气田经过10余年的高速开发后,目前面临气井快速见水和气水界面非均匀抬升等问题。为进一步明确复杂构造背景下的高压气田水侵机理,开展了气田内部基于断裂的地质力学活动性及其与气井见水之间的关联性研... 详细信息

中国陆相最大天然气田——克拉2气田经过10余年的高速开发后,目前面临气井快速见水和气水界面非均匀抬升等问题。为进一步明确复杂构造背景下的高压气田水侵机理,开展了气田内部基于断裂的地质力学活动性及其与气井见水之间的关联性研究。将气田四维地应力场建模和三维断裂力学分析相结合,建立了随气田开发的断裂力学活动性预测模型,研究了断裂活动性对气田水侵的影响。结果表明:(1)气井见水与井旁断裂力学特征变化有较好的关联性,随着气藏开采及现今地应力场的动态变化,断裂面受力状态也随之改变,从而使断裂带内部渗透性变强或变弱。(2)随气藏地层压力的下降,若井旁断层和裂缝活动性增加或保持较好,则气井见水较早,气水界面抬升较快。(3)由于气田内部应力场和断裂分布均较复杂,因此不同构造部位的断裂活动性差异较大,从而造成不同位置气水界面抬升不均匀且相差较大。研究进一步明确了克拉2气田的水侵机理,并利用断裂地质力学活动性指数将气藏划分为3个见水风险区,为气田开发方案优化提供依据。

关键词：克拉2气田断裂地质力学活动性地应力场水侵

Unlocking the stable interface in aqueous zinc-ion battery with multifunctional xylose-based electrolyte additives

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Journal of Energy Chemistry 2025年第1期100卷 770-778页

作者： xiaoqin Li Jian xiang Lu Qiu xiaohan Chen Yinkun Zhao Yujue Wang Qu Yue Taotao Gao Wenlong Liu Dan xiao Zhaoyu Jin Panpan Li Institute for Advanced Study Chengdu University School of Mechanical Engineering Chengdu University College of Food and Biological Engineering Chengdu University Institute of Fundamental and Frontier Sciences University of Electronic Science and Technology of China College of Materials Science and Engineering Sichuan University

The growth of dendrites and the side reactions occurring at the Zn anode pose significant challenges to the commercialization of aqueous Zn-ion batteries（AZIBs）. These challenges arise from the inherent conflict between mass transfer and electrochemical kinetics. In this study, we propose the use of a multifunctional electrolyte additive based on the xylose（Xylo） molecule to address these issues by modulating the solvation structure and electrode/electrolyte interface, thereby stabilizing the Zn anode. The introduction of the additive alters the solvation structure, creating steric hindrance that impedes charge transfer and then reduces electrochemical kinetics. Furthermore, in-situ analyses demonstrate that the reconstructed electrode/electrolyte interface facilitates stable and rapid Zn2+ion migration and suppresses corrosion and hydrogen evolution reactions. As a result, symmetric cells incorporating the Xylo additive exhibit significantly enhanced reversibility during the Zn plating/stripping process, with an impressively long lifespan of up to 1986 h, compared to cells using pure ZnSO4electrolyte. When combined with a polyaniline cathode, the full cells demonstrate improved capacity and long-term cyclic stability. This work offers an effective direction for improving the stability of Zn anode via electrolyte design, as well as highperformance AZIBs.

关键词： Solvation