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Function of c-Fos-like and c-jun-like Proteins on Trichostatin A-induced G2/M Arrest in Physarum polycephalum

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Acta Biochimica et Biophysica Sinica 2005年第11期37卷 767-772页

作者： xiao-Xue LI jun lu Yan-Mei ZHAO Bai-Qu HUANG Institute of Genetics and Cytology,Northeast Normal University,Changchun 130024,China Institute of Genetics and Cytology Northeast Normal UniversityChangchun 130024 China

The homologs of transcription factors c-Fos and c-jun have been detected in slime moldPhysarum polycephalum during progression of the synchronous cell *** we demonstrated that c-Fos-like and c-jun-like proteins participated in G2/M transition by the regulation of the level of Cyclin B1protein in *** study of antibody neutralization revealed that interruption of the functions ofc-Fos-like and c-jun-like proteins resulted in G2/M transition arrest,implicating their functional roles in cellcycle *** G2/M transition was blocked by histone deacetylase inhibitor trichostatin A,changes inc-Fos- and c-jun-like protein levels,and hyperacetylation of c-jun-like protein,were *** datasuggest that in ***,c-Fos- and c-jun-like proteins may be the key factors in the regulation ofhistone acetylation-related G2/M transition,involving the coordinated expression and hyperacetylation ofthese proteins.

关键词： c-Fos-like protein c-jun-like protein trichostatin A G2/M transition Physarum polycephalum

Bang Bang Control of Unified Chaotic System

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Wuhan University Journal of Natural Sciences 2003年第S1期8卷 311-315页

作者： Deng xiao-ming, lu jun-anSchool of Mathematics and Statistics,Wuhan University, Wuhan 430072,Hubei,China School of Mathematics and Statistics Wuhan University Wuhan Hubei China

The unified chaotic system contains the Lorenz system and the Chen system as two dual systems at the two extremes of its parameter spectrum. This paper presents the design of bang bang controller for unified system and multitude of numerical experiments under various control parameters. Numerical experiments meet the theoretic proof perfectly and convincingly demonstrated the controller can be effectively used for unified systems with uncertainty of the equilibrium points. The method enriches the applications of chaotic control.

关键词： chaotic control bang bang control unified system

Synchronization of Unified Chaotic System Using Occasional Driving

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Wuhan University Journal of Natural Sciences 2003年第03A期8卷 808-812页

作者： Wu xiao\|qun, lu jun\|an  School of Mathematics and Statistics, Wuhan University , Wuhan 430072, Hubei, China School of Mathematics and Statistics Wuhan University Wuhan Hubei China

The synchronization of the unified chaotic systems using occasional driving technique is studied. The relation among interim period T , sampling interval 2 ε , feedback gain r and the parameter α of the system is thoroughly investigated. Numerical results show that smaller interim period T and properly larger sampling interval 2 ε can accelerate the synchronizing pace. Furthermore, for a unified chaotic system in which α is given, we can achieve satisfying synchronizing results as long as T,ε and r are appropriately chosen. As we adopt the occasional driving method, we greatly reduce the control cost. Therefore with this method we can obtain the expecting goals with little control cost.

关键词： synchronization occasional drive unified chaotic system

Laparoscopic adrenocortical oncocytoma resection

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Chinese Medical Journal 2008年第9期121卷 862-864页

作者： TIAN xiao-jun HUANG Yi lu Jian MA lu-lin Depatment of Urology Peking University Third Hospital Beijing 100083 China

The term ＂oncocyte＂ was first used by Hamperl in 1950 to describe a kind of large, highly eosinophilic, granular tumour cell. Oncocytoma refers to the tumour that is composed of oncocytes. Oncocytoma can occur in various organs throughout the body, commonly salivary glands, thyroid or kidney and less commonly in lung, parathyroid gland, ovary or pituitary gland. Adrenocortical oncocytomas are rare： only 46 cases have been reported worldwide in the literature.2-6 Most of adrenal masses were resected by open operations.3-7 An oncocytoma of the adrenal gland was diagnosed and treated in our hospital recently. Retroperitoneal laparoscopy was performed to remove the mass. We report our recent case and review the literature.

关键词： adrenal glands adenoma oxyphilic laparoscopy

Pre-peritoneal laparoscopic partial cystectomy of the bladder pheochromocytoma

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Chinese Medical Journal 2009年第10期122卷 1234-1237页

作者： HUANG Yi TIAN xiao-jun MA lu-lin Department of Urology Peking University Third Hospital Beijing 100191 China

Pheochromocytoma （PCC） is a catecholamine producing tumor of neuroectodermal origin that is made up of chromaftin cells, anti it mostly arises from me adrenal medulla. Extra-adrenal pheochromocytomas occur in about ... 详细信息

关键词： pheochromocytoma laparoscopy partial cystectomy

Registering Different DBMSs to Panorama with CORBA

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Wuhan University Journal of Natural Sciences 2001年第Z1期6卷 423-431页

作者： Sarem Mudar, Li Rui\|xuan, xiao Wei\|jun, lu Zheng\|ding School of Computer Science, Huazhong University of Science and Technology,Wuhan 430074, China School of Computer Science Huazhong University of Science and Technology Wuhan China

Recently, there is an increasing use of CORBA implementation in developing multidatabase systems. MIND and Panorama are some of the examples of multidatabase prototypes that have been implemented on the top of CORBA compliant namely ObjectBroker and VisiBroker respectively. They both aim to achieve interoperability among Oracle, Sybase and other different DBMSs through the registration of these DBMSs to them using CORBA. This registration to a CORBA based multidatabase system offers an advanced way in achieving *** first introduce Panorama multidatabase system and discuss the basic implementation decisions in registering different DBMSs using the CORBA compliant ORB, namely VisiBroker to this system. Then, it aims to discuss the method we've used in registering different DBMSs to our designed multidatabase system Panorama. A detailed discussion about the registration of Oracle8 and Sybase is given. And finally, a conclusion and the future work for this system have been given.

关键词： heterogeneity CORBA interoperability multidatabase system

Moving Target Tracking Based on LogGabor Wavelet and Mean-shift Algorithm

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Semiconductor Photonics and Technology 2009年第2期15卷 81-85,96页

作者： DU Xian-yan HAN xiao-jun lu Wei-wei Department of Information and Communication Tianjin Polytechnic University Tianjin 300160 CHN

Tracking moving target from image or video sequence is a hot research topic in computer vision. An algorithm based on LogGabor wavelet and Mean-shift has been proposed for moving target tracking under fixed camera setting and complicated environment. Phase coherency of LogGabor wavelet facilitates to extract the edge of moving target and check noise. According to the edge detection,the starting location of Mean-shift can be estimated using the target center coordinate. Eventually,a real-time moving target can be extracted by doing iterative matching pursuit,and experimental results proved the effectiveness of the method proposed.

关键词： Mean-shift algorithm phase congruency LogGabor wavelet transformation target tracking

De novo synthesis of atropisomeric benzofurans via Cu/SPDO complex catalyzed asymmetric formal [3 + 2] annulation

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Science China Chemistry 2025年第1期68卷 174-180页

作者： Fan-xiao Meng Xing-Yu Wang Ka lu Ju-Song Yang Fu-Min Zhang Ai-jun Ma Bao Du Yong-Qiang Tu State Key Laboratory of Applied Organic Chemistry College of Chemistry and Chemical Engineering Lanzhou University School of Chemistry and Chemical Engineering Shanghai Jiao Tong University School of Biotechnology and Health Sciences Wuyi University

Herein, the de novo synthesis of atropisomeric benzofurans through the Cu/spirocyclic-pyrrolidine-oxazoline(SPDO) complex catalyze asymmetric formal [3 + 2] cycloaddition between quinones and ynamides is explored, producing a range of structurally diverse axially chiral benzofurans in satisfactory yields with good to excellent enantioselectivities. Furthermore, density functional theory calculations were applied to explain the possible reaction mechanism.

关键词： benzofuran atropisomers novel de novo synthetic strategy asymmetric formal [3 + 2] cycladdition Cu/SPDO complex DFT calculations

Serum vaspin level in relation to postprandial plasma glucose concentration in subjects with diabetes

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Chinese Medical Journal 2009年第21期122卷 2530-2533页

作者： YE Yin HOU Xu-hong PAN xiao-ping lu jun-xi JIA Wei-ping Department of Endocrinology and Metabolism Shanghai Clinical Center for Diabetes Shanghai Jiao Tong University Affiliated Sixth People's Hospital Shanghai Diabetes Institute Shanghai Key Laboratory of Diabetes Mellitus Shanghai 200233 China

Background Vaspin is a newly-identified adipocytokine related to obesity and insulin sensitivity. However, its pathophysiologic role in humans remains largely unknown. The aim of our study was to investigate the relationship between serum vaspin level and glucose metabolism or obesity in Chinese adults. Methods A total of 123 subjects, including 84 subjects with normal glucose tolerance （NGT） and 39 subjects with diabetes, were enrolled in this study. Anthropometric parameters, abdominal fat areas, plasma glucose concentration, serum insulin, lipids, and vaspin level were measured in each participant. Results Serum vaspin concentration was significantly higher in diabetic patients than that in NGT subjects （592 （438-695） pg/ml vs 380 （294-517） pg/ml, P=0.020） in women. In all participants, age, fasting plasma glucose concentration （FPG）, 2-hour post-load plasma glucose （PG2h）, hemoglobin Alc （HbAlc） and high-density lipoprotein cholesterol （HDL-c） significantly increased from the lower tertile to the higher tertile of vaspin. Univariate linear regression analyses revealed that vaspin level was only positively correlated with age （β=0.340, P=0.002） in NGT subjects. And vaspin was positively associated with FPG （β=0.365, P=0.023）, PG2h （β=0.526, P=0.001）, HbAlc （β=0.388, P=0.016）, and HDL-c （β=0.353, P=0.027）, while negatively with homeostasis model assessment of beta cell function （HOMA-β）（β=-0.361, P=-0.024） in diabetic patients. In stepwise multivariate regression analyses, age was independently associated with circulating vaspin in NGT subjects, whereas PG2h was an independent predictor of vaspin in diabetic patients. In addition, there was no significant difference of serum vaspin level between men and women. And no significant correlations between vaspin and body fat indexes were detected. Conclusions Serum vaspin level is higher in diabetic patients than that in NGT subjects in women. Age predicts serum vaspin level in NGT subjects, while PG2h is independently

关键词： vaspin protein, human blood glucose diabetes mellitus obesity