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Advances in the treatment of rhegmatogenous retinal detachment

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International Journal of Ophthalmology(English edition) 2019年第4期12卷 660-667页

作者： Li Liao xiao-hua zhu Department of Ophthalmology the Second Xiangya Hospital Central South University

The pathogenesis of rhegmatogenous retinal detachment depends on three factors, namely, retinal rupture, vitreous liquefaction and traction causing the retina to separate from the pigment epithelium, among which retinal rupture is the most important. Retinopathy is caused by a gap between the neurosensory retina and the retinal pigment epithelium, which severely damages the visual function of the patient. Therefore, early clinical discovery, prevention and selection of an appropriate treatment are important. This article reviews progress in the treatment of retinal detachment.

关键词： rhegmatogenous retinal detachment treatment progress sclera external-route surgery retinal laser photocoagulation pars plana vitrectomy

The rock breaking and ROP increase mechanisms for single-tooth torsional impact cutting using DEM

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Petroleum Science 2019年第5期16卷 1134-1147页

作者： xiao-hua zhu Yun-Xu Luo Wei-ji Liu School of Mechatronic Engineering Southwest Petroleum UniversityChengdu 610500China Postdoctoral Research Station for Oil and Gas Engineering Southwest Petroleum UniversityChengdu 610500China

Torsional impact drilling is a new technology which has the advantages of high rock-breaking efficiency and a high rate of penetration(ROP).So far,there is no in-depth understanding of the rock-breaking mechanism for the ROP increase from torsional impact ***,it has practical engineering significance to study the rock-breaking mechanism of torsional *** this paper,discrete element method(DEM)software(PFC2 D)is used to compare granite breaking under the steady and torsional impacting ***,the energy consumption to break rock,microscopic crushing process and chip characteristics as well as the relationship among these three factors for granite under different impacting frequencies and amplitudes are *** is found that the average cutting force is smaller in the case of torsional impact cutting(TIC)than that in the case of steady *** mechanical specific energy(MSE)and the ratio of brittle energy consumption to total energy are negatively correlated;rock-breaking efficiency is related to the mode of action between the cutting tooth and ***,the ROP increase mechanism of torsional impact drilling technology is that the ratio of brittle energy consumption under the TIC condition is larger than that under a steady load;the degree of repeated fragmentation of rock chips under the TIC condition is lower than that under the steady load,and the TIC load promotes the formation of a transverse cracking network near the free surface and inhibits the formation of a deep longitudinal cracking network.

关键词： Torsional impact rock breaking Mechanical specific energy Fractal dimension Microcrack DEM

Micro-macro fracture mechanism of heterogeneous granite in percussive drilling

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Petroleum Science 2023年第5期20卷 3131-3142页

作者： Wei-Ji Liu Yan-Fei Wang Zhao-Wang Dan xiao-hua zhu School of Mechatronic Engineering Southwest Petroleum UniversityChengdu610500SichuanChina Geothermal Energy Research Center Southwest Petroleum UniversityChengdu610500SichuanChina Powerchina Sinohydro Bureau 7 Co. LTDChengdu610500SichuanChina

The conventional rotary rock breaking method faces a technical bottleneck in improving the rate of penetration(ROP)in deep hard *** drilling is the most potential approach to increase rock-breaking efficiency and ***,the rock-breaking mechanism of percussive drilling is still unclear enough,especially the micro-fracture mechanism of rock under confining pressure(under lateral pressure and hydraulic pressure).In this paper,the impact rock breaking experiments by four kinds of Polycrystalline Diamond Compact(PDC)cutters are carried out using a drop-weight impact testing machine and an acoustic emission(AE)recording system,the influence of parameters such as cutter shape,rake angle,and impact energy on rock-breaking are systematically *** study includes a numerical simulation to examine the process of crack initiation,propagation,and cuttings formation during the impact process with the consideration of confining *** results show the conicalshaped cutter is the most aggressive with high breaking *** penetration depth of the cutter is mainly influenced by the impact energy and cutter shape than the rake angle of the *** exists critical impact energy makes the rock breaking efficiency the *** critical impact energy is about 40 J when using the conical-shaped cutter with a rake angle of 15°.The rock mainly failed in tensile mode,and the inter-grain crack is the main *** pressure can inhibit the formation of horizontal cracks,while lateral pressure can inhibit the formation of vertical cracks and reduce the proportion of tensile *** research results can provide some reference and basis for improving the rock-breaking efficiency in deep hard formations.

关键词： Percussive drilling PFC Rock fragmentation characteristics Rock breaking efficiency

Real-Time Characterization of Fibrinogen Interaction with Modified Titanium Dioxide Film by Quartz Crystal Microbalance with Dissipation

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Chinese Journal of Chemical Physics 2014年第3期27卷 355-360页

作者： An-sha Zhao Zhao Wang xiao-hua zhu Manfred F. Maitz Nan huang Key Laboratory of Advanced Materials Technology of Ministry of:Education Department of Materials Science and Engineering Southwest Jiaotong University Chengdu 510031 China Leibniz Institute of Polymer Research Dresden Max Bergmann Center of Biomaterials Dresden Dresden Germany

The adsorption of fibrinogen can be used as a quick indicator of surface haemocompatibility because of its prominent role in coagulation and platelet adhesion. In this work the molecular interaction between fibrinogen and a modified titanium oxide surface/platelet has been studied by quartz crystal microbalanee with dissipation （QCM-D） in situ. In order to further characterize the conformation of adsorbed fibrinogen, αC and γ-chain antibody were used to check the orientation and denaturation of fibrinogen on solid surface. QCM-D investiga- tions revealed the fibrinogen have the trend to adsorb on hydropllilic surface in a side-on orientation by positively charged αC domains, which would reduce the exposure of platelet bonding site on γ chain and enable less platelet adhesion and be activated. These obser- vations suggest that certain conformations of adsorbed fibrinogen are less platelet adhesive than others, which opens a possibility for creating a non-platelet adhesive substrates.

关键词： Quartz crystal microbalance with dissipation Fibrinogen adsorption Confor- mation change Blood platelet

Diagnosis and treatment of myopic traction maculopathy

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International Journal of Ophthalmology(English edition) 2012年第6期5卷 754-758页

作者： Ping-Bo Ouyang Xuan-Chu Duan xiao-hua zhu Department of Ophthalmology the Second Xiangya Hospital of Central South University

In recent years, the broad application of optical coherence tomography and vitrectomy, combined with research efforts in maculopathy in high myopia have provided many achievements, such as the new classification of myopic traction maculopathy (MTM). Here, we review the latest developments in the diagnosis and treatment of MTM, including its conception, clinical characteristics, pathogenesis, clinical stages, and the options for surgical treatment.

关键词： myopic traction maculopathy optical coherence tomography high myopia vitrectomy

Clinical observations of acute onset of myopic optic neuropathy in a real-world setting

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International Journal of Ophthalmology(English edition) 2021年第3期14卷 461-467页

作者： Li Liao Rui Fang Fang Fang xiao-hua zhu Department of Ophthalmology the Second Xiangya HospitalCentral South UniversityChangsha 410011Hunan ProvinceChina Changsha Aier Eye Hospital Changsha 410015Hunan ProvinceChina Department of Orthopedics the Second Xiangya HospitalCentral South UniversityChangsha 410011Hunan ProvinceChina

AIM: To describe the clinical features of acute myopic onset of optic neuropathy and observe the effects of retrobulbar and systemic glucocorticoid therapy in a realworld ***: A retrospective observational case series included 18 patients with a clinical diagnosis of acute onset of myopic optic neuropathy in a real-world setting. While the patients were using retrobulbar and systemic glucocorticoid therapy, various imaging examination data were analysed, and the clinical features of myopic optic neuropathy were summarized for 6 mo to 2 y. RESULTS: The included group of patients with acute onset of myopic optic neuropathy consisted mostly of females(n=11). The visual field(VF) showed abnormalities in bilateral eyes, including the spread of physiological blind spots, central and paracentral dark spots, and centripetal peripheral VF reduction;but central vision with no subjective changes. The visual evoked potential(VEP) was abnormal in all eyes with vision loss. The best corrected visual acuity(BCVA) was improved from 1.04±0.63 to 0.47±0.57(log MAR) af ter glucocor ticoid treatment(P0.05). There was no recurrence during long-term followup ***: The acute onset of myopic optic neuropathy is characterized by BCVA and VF abnormalities in bilateral eyes. Retrobulbar and systemic glucocorticoid therapy is effective.

关键词： acute onset of myopic optic neuropathy glucocorticoid visual field

Rhegmatogenous retinal detachment associated with massive spontaneous suprachoroidal hemorrhage and prognosis of pars plana vitrectomy

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International Journal of Ophthalmology(English edition) 2014年第5期7卷 850-854页

作者： Jie Zhang xiao-hua zhu Luo-Sheng Tang Department of Ophthalmology the Second Xiangya HospitalCentral South University

AIM:To describe the clinical characters of rhegmatogenous retinal detachment(RRD) associated with massive spontaneous suprachoroidal hemorrhage(SSCH). To evaluate optimal timing and prognosis of pars plana ***:A retrospective review of 6 cases(6 eyes)of RRD and massive SSCH among 3772 cases of RRD was conducted. All of 6 patients were treated with twenty-gauge vitrectomy, suprachoroidal blood drainage,phacoemulsification(PHACO) or lensectomy and silicon oil tamponade. The clinical characters, intraoperative findings and treatment outcomes were ***:In the 6 affected eyes of 6 patients(3 men and 3 women; mean age, 53.83y; range 34-61y),preoperative visual acuity ranged from faint light perception(LP) to counting finger(CF). The average interventional duration from visual decreased to surgery was 12.8 d(range 9-15d). All eyes were associated with high myopia and the mean ocular length was 30.32 mm(range 28.14-32.32 mm). Choroidal hemorrhage were successfully drained in the operation of all 6 *** findings showed there were multiple retinal breaks in all 6 eyes and in 4 eyes breaks were along supratemporal and/or infratemporal retinal vascular arcade, especially in the edge of chorioretinal atrophy areas. These patients were followed up from 6 to 34mo(Mean, 23.5mo). The best-corrected visual acuity after surgery varied from CF to 20/100, with improvement in 5eyes(83.33%) and no change in 1 eye(16.67%). Ocular hypertension ocurred in 1 eye(16.67%), which wassuccessfully treated by silicon oil removal combined with trabeculectomy. In 4 eyes, tractional retinal detachment caused by proliferative vitreoretinopathy(PVR) appeared and a secondary surgery of pre-retinal membrane peeling and silicon oil retained were performed. In 4eyes, silicon oil cannot be removed. The initial and final reattachment rates were 33.33% and 66.67%, ***:RRD associated with massive SSCH is an extremely rare event. The most common risk

关键词： rhegmatogenous retinal detachment suprachoroidal hemorrhage pars plana vitrectomy

The largest CPIES array in the marginal sea:abundant dynamics in the northeast South China Sea

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Acta Oceanologica Sinica 2024年第1期43卷 135-137页

作者： hua Zheng xiao-hua zhu Min Wang Ruixiang Zhao Chuanzheng Zhang Feng Nan Fei Yu Institute of Polar and Ocean Technology Second Institute of OceanographyMinistry of Natural ResourcesHangzhou 310012China State Key Laboratory of Satellite Ocean Environment Dynamics Second Institute of OceanographyMinistry of Natural ResourcesHangzhou 310012China School of Oceanography Shanghai Jiao Tong UniversityShanghai 200030China Southern Marine Science and Engineering Guangdong Laboratory(zhuhai) Zhuhai 519082China National Marine Environmental Monitoring Center Dalian 116023China Key Laboratory of Ocean Circulation and Waves Institute of OceanologyChinese Academy of SciencesQingdao 266071China University of Chinese Academy of Sciences Beijing 100049China Center for Ocean Mega-Science Chinese Academy of SciencesQingdao 266071China Laboratory for Ocean and Climate Dynamics Qingdao National Laboratory for Marine Science and TechnologyQingdao 266237China

The South China Sea(SCS)is a marginal sea connecting the Pacific and Indian oceans and has gained much attention in recent *** dynamics in the northeast SCS are considerably influenced by topography,monsoons,tropical ... 详细信息

关键词： northeast marginal abundant

Detection of time varying pitch in tonal languages: an approach based on ensemble empirical mode decomposition

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Journal of Zhejiang University-Science C(Computers and Electronics) 2012年第2期13卷 139-145页

作者： Hong HONG xiao-hua zhu Wei-min SU Run-tong GENG Xin-long WANG School of Electronic Engineering and Optoelectronic Techniques Nanjing University of Science and TechnologyNanjing 210094China State Key Laboratory of Modern Acoustics Institute of AcousticsNanjing UniversityNanjing 210093China

A method based on ensemble empirical mode decomposition (EEMD) is proposed for accurately detecting the time varying pitch of speech in tonal languages. Unlike frame-, event-, or subspace-based pitch detectors, the time varying information of pitch within the short duration, which is of crucial importance in speech processing of tonal languages, can be accurately extracted. The Chinese Linguistic Data Consortium (CLDC) database for Mandarin Chinese was employed as standard speech data for the evaluation of the effectiveness of the method. It is shown that the proposed method provides more accurate and reliable results, particularly in estimating the tones of non-monotonically varying pitches like the third one in Mandarin Chinese. Also, it is shown that the new method has strong resistance to noise disturbance.

关键词： Ensemble empirical mode decomposition Time varying pitch Tonal language Noise restraint