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Asymptotic Approximations of Jacobi Functions and Their Zeros with Error Bounds

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Acta Mathematica Sinica,English Series 2006年第3期22卷 729-740页

作者： xiao feng zhu Xiu Chun LI Department of Basic Science Beijing Institute of Graphic Communication

The study of zeros of orthogonal functions is an important topic. In this paper, by improving the middle variable x（t）, we＇ve got a new form of asymptotic approximation, completed with error bounds, it is constructed for the Jacobi functions φu^（α,β）（t）（α 〉 -1） as μ→∞. Besides, an accurate approximation with error bounds is also constructed correspondingly for the zeros tμ,s of φu^（α,β）（t）（α≥ 0） as μ→∞, uniformly with respect to s = 1, 2,....

关键词： Asymptotic approximation Jacobi function Zero Error bounds

Parathyroid adenoma combined with a rib tumor as the primary disease: A case report

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World Journal of Clinical Cases 2020年第19期8卷 4681-4687页

作者： Lu Han xiao-feng zhu College of Medicine Jiamusi UniversityJiamusi 154000Heilongjiang ProvinceChina Department of Thoracic Surgery The First Affiliated Hospital of Jiamusi UniversityJiamusi 154000Heilongjiang ProvinceChina

BACKGROUND Parathyroid adenoma is a benign parathyroid tumor,with serum parathyroid hormone and calcium ion concentrations as the typical basis for *** clinical manifestations are complex and changeable;thus it is easily missed or *** 85%of patients with parathyroid adenoma develop primary hyperparathyroidism,and abnormalities in bones,kidneys and other organs can *** tumors are *** SUMMARY We report a rare case of fibrocystic osteitis associated with a parathyroid adenoma,which was discovered by chance due to a rib *** elevated serum parathyroid hormone and calcium ion were found before *** suspected primary hyperparathyroidism,and color Doppler ultrasound suggested the presence of a thyroid *** informed consent by the patient and her family,we first removed the rib tumor,and one week later,resection of the parathyroid adenoma and thyroid mass was performed on both sides,and the patient recovered well after *** In the case of parathyroid adenoma combined with brown tumor,the bone cyst will gradually decrease in size with time without *** not,surgery should be performed as soon as possible.

关键词： Parathyroid adenoma Rib Brown tumor Primary hyperparathyroidism Treatment Operation Case report

Electrolyte perspective on stabilizing LiNi_(0.8)Co_(0.1)Mn_(0.1)O_(2)cathode for lithium-ion batteries

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Rare Metals 2023年第2期42卷 387-398页

作者： xiao-feng zhu Xiu Li Tian-Quan Liang Xin-Hua Liu Jian-Min Ma School of Resources Environment and MaterialsGuangxi UniversityNanning530004China School of Materials and Energy University of Electronic Science and Technology of ChinaChengdu611731China School of Transportation Science and Engineering Beihang UniversityBeijing102206China

Nickel-rich LiNi_(0.8)Co_(0.1)Mn_(0.1)O_(2)(NCM811)is regarded as the promising cathode for lithium-ion batteries(LIBs).However,the challenges such as safety issues and poor cycling performance have seriously hindered its commercial *** order to overcome these difficulties,there has been extensive research and development of electrolyte modifications for high-energy-density LIBs with Ni-rich ***,this review introduces the research progress based on solvent additives,salt type additives and other electrolytes for LIBs with NCM811cathode materials and discusses how they control the interface *** particular,some recommendations for further modification of enhancing electrolyte stability and improving NCM811 electrochemical properties are summarized and proposed,which put forward new design rules for the screening and customizing ideal electrolyte additives for high performance NCM811 cathode-based LIBs.

关键词： Nickel-rich LiNi_(0.8)Co_(0.1)Mn_(0.1)O_(2)(NCM811) Interface Electrolyte additives Cathode electrolyte interphase(CEI) Electrolyte

miR-26a regulates mouse hepatocyte proliferation via directly targeting the 3' untranslated region of CCND2 and CCNE2

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Hepatobiliary & Pancreatic Diseases International 2016年第1期15卷 65-72页

作者： Jian Zhou Wei-Qiang Ju xiao-Peng Yuan xiao-feng zhu Dong-Ping Wang xiao-Shun He Organ Transplant Center the First Affiliated HospitalSun Yat-Sen University

BACKGROUND： The deficiency of liver regeneration needs to be addressed in the fields of liver surgery, split liver transplan- tation and living donor liver transplantation. Researches of microRNAs would broaden our understandings on the mecha- nisms of various diseases. Our previous research confirmed that miR-26a regulated liver regeneration in mice; however, the relationship between miR-26a and its target, directly or in- directly, remains unclear. Therefore, the present study further investigated the mechanism of miR-26a in regulating mouse hepatocyte proliferation. METHODS： An established mouse liver cell line, Nctc-1469, was transfected with Ad5-miR-26a-EGFP, Ad5-anti-miR-26a- EGFP or AdS-EGFP vector. Cell proliferation was assessed by MTS, cell apoptosis and cell cycle by flow cytometry, and gene expression by Western blotting and quantitative real-time PCR. Dual-luciferase reporter assays were used to test targets of miR-26a. RESULTS： Compared with the Ad5-EGFP group, Ad5-anti- miR-26a-EGFP down-regulated miR-26a and increased prolif- eration of hepatocytes, with more cells entering the G1 phase of cell cycle （82.70%＋1.45% vs 75.80%＋_3.92%）, and decreased apoptosis （5.50%＋0.35% vs 6.73%_＋0.42%）. CCND2 and CCNE2 were the direct targeted genes of miR-26a, miR-26a down- regulation up-regulated CCND2 and CCNE2 expressions and down-regulated p53 expression in Nctc-1469 cells. On the con- trary, miR-26a over-expression showed the opposite results. CONCLUSIONS： miR-26a regulated mouse hepatocyte pro- liferation by directly targeting the 3＇ untranslated regions of cyclin D2/cyclin E2; miR-26a also regulated p53-mediated apoptosis. Our data suggested that miR-26a may be a promis- ing regulator in liver regeneration.

关键词： microRNA miR-26a gene expression hepatocyte proliferation regulation

Recovery of alkali and alumina from Bayer red mud by the calcification–carbonation method

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International Journal of Minerals,Metallurgy and Materials 2016年第3期23卷 257-268页

作者： xiao-feng zhu ting-an zhang yan-xiu wang guo-zhi lü wei-guang zhang Key Laboratory of Ecological Utilization of Multi-metal Intergrown Ores of the Ministry of Education School of Materials and MetallurgyNortheastern UniversityShenyang 110819China

Red mud produced in the Bayer process is a hazardous solid waste because of its high alkalinity; however, it is rich in valuable components such as titanium, iron, and aluminum. In this study, a novel calcification-carbonation method was developed to recover alkali and alumina from Bayer red mud under mild reaction conditions. Batch experiments were performed to evaluate the potential effects of im- portant parameters such as temperature, amount of CaO added, and CO2 partial pressure on the recovery of alkali and alumina. The results showed that 95.2% alkali and 75.0% alumina were recovered from red mud with decreases in the mass ratios of Na2O to Fe2O3 and of Al2O3 to Fe2O3 from 0.42 and 0.89 to 0.02 and 0.22, respectively. The processed red mud with less than 0.5wt% Na2O can potentially be used as a construction material.

关键词： waste utilization red mud calcification carbonation alumina alkali recovery

Hydrothermal conversion of Ti-containing minerals in system of Na_2O–Al_2O_3–SiO_2–CaO–TiO_2–H_2O

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Rare Metals 2016年第6期35卷 495-501页

作者： Yan-Xiu Wang Ting-An Zhang Guo-Zhi Lv xiao-feng zhu Wei-Guang Zhang Li-Qun Xie Key Laboratory for Ecological Utilization of Multimetallic Mineral Ministry of Education Northeastern University Shenyang 110819 China

Titanium has a great effect on the digestion of bauxite in the Bayer process because it reacts readily at high temperatures in alkaline sodium aluminate solution. Under this consideration, the hydrothermal conversion of Ti-containing minerals in the system of Na2O-Al2O3- SiO2-CaO-TiOz-H2O with increased temperatures was studied based on the thermodynamic analysis and systematic experiments. The results show that anatase converts to AlaTi2SiO12 at low temperatures （60-120℃）, which is similar to anatase in crystal structure. As the temperature continues to rise, Al4Ti2SiO12 decomposes gradually and converts to Ca3TiSi2（Al2Si0.5Ti0.5）O14 at 200 ℃ When the temperature reaches 260℃, CaTiO3 forms as the most stable titanate species for its hexagonal closest packing with O^2- and Ca^2＋. The findings enhance the under-standing of titanate scaling in the Bayer process and clarify the mechanism of how additive lime improves the digestion of diaspore.

关键词： Hydrothermal conversion Ti-containing minerals Bayer process Anatase Aluminosilicate

Application of extended criteria donor grafts in liver transplantation for acute-on-chronic liver failure:A retrospective cohort study

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World Journal of Gastroenterology 2023年第41期29卷 5630-5640页

作者： Jin-Long Gong Jia Yu Tie-Long Wang xiao-Shun He Yun-Hua Tang xiao-feng zhu Department of Hepatobiliary Surgery Hunan Provincial People's HospitalThe First Affiliated Hospital of Hunan Normal UniversityChangsha 410005Hunan ProvinceChina Organ Transplant Center The First Affiliated HospitalSun Yat-sen UniversityGuangzhou 510080Guangdong ProvinceChina Department of Gastroenterology Surgery The First Affiliated Hospital of University of South ChinaHengyang 421005Hunan ProvinceChina

BACKGROUND There is no consensus on the usage of extended criteria donor(ECD)grafts in liver transplantation(LT)for acute-on-chronic liver failure(ACLF)*** To summarize the experience of using ECD livers in *** A retrospective cohort study was conducted,enrolling patients who underwent LT at the First Affiliated Hospital of Sun Yat-Sen University from January 2015 to November *** patients were divided into ECD and non-ECD groups for *** A total of 145 recipients were enrolled in this study,of which ECD and non-ECD recipients accounted for 53.8%and 46.2%,*** after cardiac death(DCD)recipients accounted for the minority compared with donation after brain death(DBD)recipients(16.6%vs 83.4%).Neither overall survival nor graft survival significantly differed between ECD and non-ECD and DCD and DBD *** grafts were associated with a significantly higher incidence of early allograft dysfunction(EAD)than non-ECD grafts(67.9%vs 41.8%,P=0.002).Postoperative outcomes between DCD and DBD recipients were comparable(P>0.05).ECD graft(P=0.009),anhepatic phase(P=0.034)and recipient gamma glutamyltransferase(P=0.016)were independent risk factors for *** preoperative number of extrahepatic organ failures>2(P=0.015)and intraoperative blood loss(P=0.000)were independent predictors of poor post-LT *** Although related to a higher risk of EAD,ECD grafts can be safely used in *** main factors affecting post-LT survival in ACLF patients are their own severe preoperative disease and intraoperative blood loss.

关键词： Extended criteria donor Acute-on-chronic liver failure Liver transplantation

Inhibition of KLF7-Targeting Micro RNA 146b Promotes Sciatic Nerve Regeneration

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Neuroscience Bulletin 2018年第3期34卷 419-437页

作者： Wen-Yuan Li Wei-Ting Zhang Yong-Xia Cheng Yan-Cui Liu feng-Guo Zhai Ping Sun Hui-Ting Li Ling-xiao Deng xiao-feng zhu Ying Wang Department of Anatomy Mudanjiang College of Medicine The Affiliated Hongqi Hospital Mudanjiang College of Medicine Department of Pathology Mudanjiang College of Medicine Department of Pharmacy Mudanjiang College of Medicine Spinal Cord and Brain Injury Research Group Stark Neuro-sciences Research Institute Indiana University School of Medicine

A previous study has indicated that Krüppel-like factor 7（KLF7）, a transcription factor that stimulates Schwann cell（SC） proliferation and axonal regeneration after peripheral nerve injury, is a promising therapeutic transcription factor in nerve injury. We aimed to identify whether inhibition of micro RNA-146 b（mi R-146 b）affected SC proliferation, migration, and myelinated axon regeneration following sciatic nerve injury by regulating its direct target KLF7. SCs were transfected with mi RNA lentivirus, mi RNA inhibitor lentivirus, or KLF7 si RNA lentivirus in vitro. The expression of mi R146 b and KLF7,as well as SC proliferation and migration, were subsequently evaluated. In vivo, an acellular nerve allograft（ANA） followed by injection of GFP control vector or a lentiviral vector encoding an mi R-146 b inhibitor was used to assess the repair potential in a model of sciatic nerve gap. mi R-146 b directly targeted KLF7 by binding to the 30-UTR, suppressing KLF7. Up-regulation of mi R-146 b and KLF7 knockdown significantly reduced the proliferation and migration of SCs, whereas silencing mi R-146 b resulted in increased proliferation and migration. KLF7 protein was localized in SCs in which mi R-146 b was expressed in ***, 4 weeks after the ANA, anti-mi R-146 b increased KLF7 and its target gene nerve growth factor cascade, promoting axonal outgrowth. Closer analysis revealed improved nerve conduction and sciatic function index score, and enhanced expression of neurofilaments, P0（anti-peripheral myelin）, and myelinated axon regeneration. Our findings provide new insight into the regulation of KLF7 by mi R-146 b during peripheral nerve regeneration and suggest a potential therapeutic strategy for peripheral nerve injury.

关键词： miR-146b KLF7 Schwann cells Sciatic nerve injury

Small nucleolar RNAs (snoRNAs) as potential non-invasive biomarkers for early cancer detection

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Chinese Journal of Cancer 2013年第2期32卷 99-101页

作者： Wen-Dan Chen xiao-feng zhu State Key Laboratory of Oncology in South China Sun Yat-sen University Cancer Center

Small nucleolar RNAs (snoRNAs) are non-coding RNA (ncRNA) molecules,which are associated with specific proteins to form small nucleolar ***,the function of snoRNAs in cancer still remains ***,several independent lines of evidence have indicated that these ncRNAs might have crucial roles in controlling tumorigenesis,and snoRNAs could be potential biomarkers for cancer.

关键词：核仁小分子RNA 生物标志物癌症检测侵入性非编码RNA 早期蛋白质肿瘤