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胃肠病学 2000年第B8期5卷 149-149页

作者： HeXing-xiang WangJia-long WuJi-li Dept.ofGastroenterology TongjiHospitalTongjiMedicalUniversityWuhan430030China

AsyCo: an asymmetric dual-task co-training model for partial-label learning

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Science China(Information Sciences) 2025年

作者： Beibei li Yiyuan ZHENG Beihong JIN Tao xiang Haobo WANG Lei FENG College of Computer Science Chongqing University State Key Laboratory of Computer Science Institute of Software Chinese Academy of Sciences University of Chinese Academy of Sciences School of Software Technology Zhejiang University School of Computer Science and Engineering Nanyang Technological University

Partial-label learning (PLL) is a typical problem of weakly supervised learning, where each training instance is annotated with a set of candidate labels. Self-training PLL models achieve state-of-the-art performance but suffer from error accumulation problems caused by mistakenly disambiguated instances. Although co-training can alleviate this issue by training two networks simultaneously and allowing them to interact with each other, most existing co-training methods train two structurally identical networks with the same task, i.e., are symmetric, rendering it insufficient for them to correct each other due to their similar limitations. Therefore, in this paper, we propose an asymmetric dual-task co-training PLL model called AsyCo,which forces its two networks, i.e., a disambiguation network and an auxiliary network, to learn from different views explicitly by optimizing distinct tasks. Specifically, the disambiguation network is trained with a self-training PLL task to learn label confidence, while the auxiliary network is trained in a supervised learning paradigm to learn from the noisy pairwise similarity labels that are constructed according to the learned label confidence. Finally, the error accumulation problem is mitigated via information distillation and confidence refinement. Extensive experiments on both uniform and instance-dependent partially labeled datasets demonstrate the effectiveness of AsyCo.

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Preparation of the Probe of hTR and Examination of the Expression of hTR in Gastric Mucosa

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胃肠病学 2000年第B8期5卷 149-149页

作者： HeXing-xiang WangJia-long WuJi-li Dept.ofGastroenterology TongjiHospitalTongjiMedicalUniversityWuhan430030Chian

According to the published hTR sequences a pair of primers were synthesized, then the cDNA fragments of hTR were amplified by RT-PCR using Hela cellular total RNA as template. The cDNA probe of hTR was prepared. The expressions of hTR were examined by RNA dot hybridization in different gastric mucosa, and the telomerase activity were detected by TRAP. The results showed that we successfully prepared the probe of hTR and established a criterion of judging hTR expression in gastric mucosa by RNA dot hybridization using human gastric carcinoma cell HS746T.

关键词： hTR 探测器基因表达胃黏膜胃癌消化系统肿瘤

Endoplasmic reticulum stress and autophagy in cerebral ischemia/reperfusion injury:PERK as a potential target for intervention

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Neural Regeneration Research 2025年第5期20卷 1455-1466页

作者： Ju Zheng Yixin li Ting Zhang Yanlin Fu Peiyan long Xiao Gao Zhengwei Wang Zhizhong Guan Xiaolan Qi Wei Hong Yan Xiao Key Laboratory of Endemic and Ethnic Diseases Ministry of Education&Key Laboratory of Medical Molecular Biology of Guizhou ProvinceGuizhou Medical UniversityGuiyangGuizhou ProvinceChina Guizhou Center for Disease Control and Prevention GuiyangGuizhou ProvinceChina Department of Histology and Embryology Guizhou Medical UniversityGuiyangGuizhou ProvinceChina Collaborative Innovation Center for Prevention and Control of Endemic and Ethnic Regional Diseases Co-constructed by the Province and Ministry GuiyangGuizhou ProvinceChina

Several studies have shown that activation of unfolded protein response and endoplasmic reticulum(ER)stress plays a crucial role in severe cerebral ischemia/reperfusion *** occurs within hours after cerebral ischemia,but the relationship between ER stress and autophagy remains *** this study,we established experimental models using oxygen-glucose deprivation/reoxygenation in PC12 cells and primary neurons to simulate cerebral ischemia/reperfusion *** found that prolongation of oxygen-glucose deprivation activated the ER stress pathway protein kinase-like endoplasmic reticulum kinase(PERK)/eukaryotic translation initiation factor 2 subunit alpha(e IF2α)-activating transcription factor 4(ATF4)-C/EBP homologous protein(CHOP),increased neuronal apoptosis,and induced ***,inhibition of ER stress using inhibitors or by si RNA knockdown of the PERK gene significantly attenuated excessive autophagy and neuronal apoptosis,indicating an interaction between autophagy and ER stress and suggesting PERK as an essential target for regulating *** autophagy with chloroquine exacerbated ER stress-induced apoptosis,indicating that normal levels of autophagy play a protective role in neuronal injury following cerebral ischemia/reperfusion *** from this study indicate that cerebral ischemia/reperfusion injury can trigger neuronal ER stress and promote autophagy,and suggest that PERK is a possible target for inhibiting excessive autophagy in cerebral ischemia/reperfusion injury.

关键词： apoptosis ATF4 autophagy C/EBP homologous protein cerebral ischemia/reperfusion injury eIF2α endoplasmic reticulum stress PERK

Substrate bias effects in p-channel GaN-on-Si transistors

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Science China(Information Sciences) 2025年第1期68卷 404-405页

作者： Mengyao ZHAO Jie MA Lanlan YANG Chuanqi PAN Denggui WANG Jianjun ZHOU Sheng li Jiaxing WEI long ZHANG Siyang liU Weifeng SUN National ASIC System Engineering Research Center School of Integrated Circuits Southeast University National Center of Technology Innovation for Electronic Design Automation Southeast University National Key Laboratory of Solid-State Microwave Devices and Circuits

The drain current （ID） of the n-channel GaN field-effecttransistor （n-FET） is influenced by the substrate-to-source bias voltage (VBS)（substrate bias effect）[1].Actually,nonzero VBSis also likely to occur in p-FET in real application,because the source electrode of p-FET is usually connected to high *** study reports the dependency between IDand VBSin p-FET for the first time,and analyzes the underlying mechanisms from the perspective of vertical electric field （EF） distribution.

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组合桨搅拌槽内非牛顿流体的气液分散特性

化学工程 2015年第7期43卷 44-48页

作者：郭晓攀周国忠龙湘犁谢明辉虞培清华东理工大学化学工程联合国家重点实验室上海200237 浙江长城减速机有限公司浙江温州325019

采用Brookfield黏度仪测量了质量分数为0.5%,1.0%,1.5%的羧甲基纤维素钠(CMC)水溶液在298.15 K的流变特性。在直径为0.48 m的平底搅拌槽中,对搅拌槽内不同的3层组合桨的气液二相的分散特性进行了实验研究,考察了非牛顿流体浓度、桨型组... 详细信息

采用Brookfield黏度仪测量了质量分数为0.5%,1.0%,1.5%的羧甲基纤维素钠(CMC)水溶液在298.15 K的流变特性。在直径为0.48 m的平底搅拌槽中,对搅拌槽内不同的3层组合桨的气液二相的分散特性进行了实验研究,考察了非牛顿流体浓度、桨型组合、通气量和搅拌转速对通气功率、相对功率和气含率的影响规律。结果表明:CMC水溶液为假塑性流体,幂律方程能很好地关联其流变特性。在相同操作条件下,随着浓度的增加气含率减小,功率消耗增加;在相同的功率输入时,下压桨型组合的气含率更高。相对功率(PG/P)、气含率关联式等研究结果对非牛顿流体的气液搅拌器设计和操作具有一定参考价值。

关键词：气液分散气含率通气功率假塑性流体搅拌槽

Multivariate synergy for heightening ionic HOF robustness and proton conductivity

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Science China Chemistry 2025年

作者： xiang-Tian Bai li-Hui Cao Xu-Yong Chen Jia-Yu Wang Zi-Ye Zhou Shaanxi Key Laboratory of Chemical Additives for Industry College of Chemistry and Chemical EngineeringShaanxi University of Science and Technology

Multicomponent crystalline materials construct more complex and diversified structures with different combinations and modes,which expands the material structure space and application *** this work,we have successfully synthesized two twocomponent ionic hydrogen-bonded organic frameworks （iHOF-32 and iHOF-33） and a three-component iHOF （iHOF-34）.Guanidine hydrochloride which is rich in N and H and has a short chain length strengthens the hydrogen bonding network of iHOF,thereby aiding in the efficient migration of *** rigid architecture of 1,1'-diamino-4,4'-bipyridine diiodide furnishes additional scaffolding for the iHOFs and enhances its robustness under harsh ***-34 accomplishes the combination of the ultra-high proton conductivity of iHOF-32 and the robustness of iHOF-33 by the synergistic interaction among the three components of *** addition,iHOF-34 was fabricated as a composite membrane with a peak proton conductivity of 1.55×10-1S cm-1,which is 3.8 times higher than that of recast Nafion,and has extensive potential in fuel *** self-assembly strategy of multicomponent HOFs opens up new avenues for constructing diverse structures while promising new opportunities for applications in the fields of proton conduction and energy storage.

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填料层压降数学模型

石油化工设备 2000年第3期29卷 16-19页

作者：龙湘犁叶永恒华东理工大学上海200237 北京化工大学北京100029

根据质量和动量守恒原理 ,考虑下降液膜和气相的相互作用、系统内气液两相流动、物性特征以及填料结构参数对压降的影响 ,提出了填料塔内规整填料的压降模型。经验证 ,该模型与本课题板网填料的实测压降数据吻合较好。由于该模型包括的... 详细信息

根据质量和动量守恒原理 ,考虑下降液膜和气相的相互作用、系统内气液两相流动、物性特征以及填料结构参数对压降的影响 ,提出了填料塔内规整填料的压降模型。经验证 ,该模型与本课题板网填料的实测压降数据吻合较好。由于该模型包括的影响因素比较全面 ,可供预测其它规整填料压降时参考。

关键词：填料流体力学模型压力降填料塔

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复合板网填料液相传质性能

石油化工设备 2000年第1期29卷 13-15页

作者：龙湘犁叶永恒华东理工大学上海200237 北京化工大学北京100029

在５００ｍｍ冷模实验塔内对３种２５０Ｙ型板网填料进行氧解吸实验，结果表明３层板网复合填料的分离效率明显高于单层板网填料，尤其在液气比低的工况下，效率可以倍增。

关键词：传质填料分离复合板钢液相填料塔

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蒸发冷却空调送风状态点的确定方法探讨

西安航空学院学报 2017年第3期35卷 88-90页

作者：宋祥龙樊丽娟黄翔西安航空学院能源与建筑学院陕西西安710077 西安工程大学环境与化学工程学院陕西西安710048

从制冷降温原理的角度出发,通过与传统机械制冷空调送风状态点的确定方法进行对比,介绍了蒸发冷却空调的空气处理过程中直接蒸发冷却等焓降温、间接蒸发冷却等湿降温、复合式蒸发冷却先等湿降温后等焓降温的特点。根据以上特点,针对不... 详细信息

从制冷降温原理的角度出发,通过与传统机械制冷空调送风状态点的确定方法进行对比,介绍了蒸发冷却空调的空气处理过程中直接蒸发冷却等焓降温、间接蒸发冷却等湿降温、复合式蒸发冷却先等湿降温后等焓降温的特点。根据以上特点,针对不同的空调系统形式,分析了确定蒸发冷却空调送风状态点的图解法与计算法。最后分别以全空气、空气—水系统为例,详细说明了计算法的计算步骤及公式。

关键词：蒸发冷却图解法计算法热湿平衡