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China Geology 2024年第1期7卷 153-156页

作者： xiang-yuan Yue Qian Zhang jun-jun Zhang Wei Zhang Jing Zhang Zhi-quan Jia Li-ping Luo Institute of Multipurpose Utilization of Mineral Resources Chinese Academy of Geological SciencesChengdu610041China Shandong Lunan Geology and Exploration Institute(No.2 Brigade of Shandong BGMR) Jining272100China Sichuan Shudao Advanced Material Science Group Co.Ltd. Chengdu610041China No.3 Geological Brigade of Sichuan Province Chongzhou611230China

*** Pegmatite hosts important resource of rare metals,e.g.,lithium(Li)and beryllium(Be).In recent years,increasingly more studies were dedicated to characterize and unravel the formation of pegmatite-type deposits,for which accurate dating of pegmatite formation and mineralization is *** Songpan-Ganzi orogenic belt is a major rare metal metallogenic belt in China,hosting many important pegmatite-type Li deposits,including the Lijiagou,Dangba,Jiajika,Yelonggou,Cuola,and *** age data(mica Ar-Ar and zircon/cassiterite U-Pb)from these Li deposits are sparse,ranging from 210 to 152 ***,obtaining reliable zircon U-Pb dates can be a challenge due to the strong decidualization in *** a result,the formation and mineralization ages of these rare metal pegmatites remain controversial,which hampers the development of pegmatite-type metallogenic model for the Songpan-Ganzi orogenic belt.

关键词： dating metallogenic zircon

MoS2 as a cocatalyst applied in advanced oxidation processes for enhancing degradation of organic pollutants: a review

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Tungsten 2024年第3期6卷 473-487页

作者： Ming-Hao Fan Cong-Hui Wang xiang Yu jun Ding Ao-Qi Xiao Yue Li Wei-Ya Huang School of Material Science and Engineering Henan Polytechnic University School of Chemical and Printing-Dyeing Engineering Henan International Joint Laboratory of Rare Earth Composite Materials Henan University of Engineering School of Chemistry and Chemical Engineering Jiangxi University of Science and Technology Department of Chemical and Environmental Engineering University of Cincinnati

Fenton technology,as a typical advanced oxidation processes（AOPs）,can generate reactive oxygen species（ROS） of strong oxidation capacity to degrade organic pollutants,which has attracted wide ***,it is accompanied by the slow Fe3+/Fe2+cycle rate,easy to generate iron sludge and so ***,it has been proven that the inorganic cocatalysts represented by MoS2can effectively solve the above ***,MoS2can accelerate the activation of peroxy mono sulfate（PMS） and peroxodisulfate（PDS） by Fe2+.In this paper,MoS2as the cocatalyst in H2O2+Fe2+,PMS+Fe2+and PDS+Fe2+were comprehensively ***,the cycling processes of Fe3+/Fe2+in different systems,the cocatalytic effect of MoS2by the exposed active sites,the ROS generation mechanism as well as the microscopic mechanism during the reaction were elaborated *** results indicate that the reductive active sites on the surface of MoS2can promote the regeneration of Fe2+through the cycle between Fe3+/Fe2+and Mo4+/Mo5+/Mo6+.Thus,ROS such as ·OH,SO4·-and1O2with strong oxidizing property can be produced to improve the degradation efficiency of organic *** last,the challenges and developments of MoS2cocatalysts in AOPs for practical applications were *** review contributes to a deeper understanding of the cocatalytic effect of two-dimensional metal sulfides in AOPs and facilitates their industrial application.

关键词： Cocatalyst Fenton reaction Degradation of organic pollutant Molybdenum disufide Reactive oxygen species

An Outbreak of Serogroup Y Meningococcal Meningitis in a Private Secondary Vocational School-Guangzhou City,Guangdong Province,China,2023

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China CDC weekly 2024年第12期6卷 242-246,I0005页

作者： xiang Zeng Qing He Yilan Li Yong Zhou Xiaoping Shao pei Hu Jian Liang Yudan Song Chao Ma Lijie Zhang Limei Sun Lei Luo Chinese Field Epidemiology Training Program Chinese Center for Disease Control and PreventionBeijingChina Zhuhai Center for Disease Control and Prevention Zhuhai CityGuangdong ProvinceChina Guangdong Center for Disease Control and Prevention Guangzhou CityGuangdong ProvinceChina Guangzhou Center for Disease Control and Prevention Guangzhou CityGuangdong ProvinceChina Institute of Public Health Guangzhou Medical University&Guangzhou Center for Disease Control and PreventionGuangzhou CityGuangdong ProvinceChina Department of the National Immunization Programme Chinese Center for Disease Control and PreventionBeijingChina

What is already known about this topic?The inclusion of meningococcal vaccines in the National Immunization Program(NIP)over several years has significantly reduced the incidence of meningococcal meningitis in China to historic ***,there has been a diversification of meningococcal serogroups,leading to a shift in dominant serogroups in China from serogroup A to serogroups C and B,accompanied by a rise in reports of serogroups Y and *** is added by this report?An outbreak of serogroup Y Neisseria meningitidis(Nm)in a secondary vocational school involved a single confirmed severe case and 24 individuals with laboratory-confirmed Nm *** investigation revealed that the outbreak was localized to the classroom of the confirmed *** close contact within a confined space was identified as a significant risk factor for Nm *** genotype sequence identified was type 1655(ST-1655),which is categorized under clonal complex 23(CC-23)and bears resemblance to 8 previously confirmed cases of serogroup Y meningococcal meningitis within Guangdong *** suggests that serogroup Y infections continue to sporadically emerge and have become prevalent *** are the implications for public health practice?This outbreak underscores the critical need to enhance surveillance of meningococcal serogroups and population carrier,and advocate for vaccination with MenY-containing vaccines.

关键词： break Secondary Guangdong

Spectrally resolved Franson interference

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Science China(Physics,Mechanics & Astronomy) 2024年第5期67卷 11-17页

作者： Rui-Bo Jin Zi-Qi Zeng Dan Xu Chen-Zhi Yuan Bai-Hong Li You Wang Ryosuke Shimizu Masahiro Takeoka Mikio Fujiwara Masahide Sasaki pei-xiang Lu Hubei Key Laboratory of Optical Information and Pattern Recognition Wuhan Institute of TechnologyWuhan 430205China School of Physics and Information Science Shaanxi University of Science and TechnologyXi'an 710021China Southwest Institute of Technical Physics Chengdu 610041China Graduate School of Informatics and Engineering University of Electro-CommunicationsTokyo 182-8585Japan Department of Electronics and Electrical Engineering Keio UniversityKanagawa 223-8522Japan National Institute of Information and Communications Technology Tokyo 184-8795Japan

Franson interference can be used to test the nonlocal features of energy-time entanglement and has become a standard in quantum ***,most of the previous Franson interference experiments were demonstrated in the time domain,and the spectral properties of Franson interference have not been fully ***,we theoretically and experimentally demonstrate spectrally resolved Franson interference using biphotons with different correlations,including positive correlation,negative correlation,and *** is found that the joint spectral intensities of the biphotons can be modulated along both the signal and idler directions,which has potential applications in generating high-dimensional frequency entanglement and time-frequency grid *** work may provide a new perspective for understanding the spectral-temporal properties of the Franson interferometer.

关键词： resolved correlation spectral

Ionization Potential Depression Model for Warm/Hot and Dense Plasmas

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Chinese Physics Letters 2024年第8期41卷 45-57页

作者： Chensheng Wu Fuyang Zhou jun Yan xiang Gao Yong Wu Chunhua Zeng Jianguo Wang Institute of Applied Physics and Computational Mathematics Beijing 100088China Faculty of Science Kunming University of Science and TechnologyKunming 650500China

For warm/hot and dense plasmas(WDPs),ionization potential depression(IPD)plays a crucial role in determining its ionization balance and understanding the resultant microscopic plasma properties.A sophisticated and unified IPD model is necessary to resolve those existing discrepancies between theoretical and experimental ***,the applicability of those widely used IPD models nowadays is limited,especially for the nonlocal thermodynamic equilibrium(non-LTE)dense plasma produced by short-pulse *** this work,we propose an IPD model that considers inelastic atomic processes,in which three-body recombination and collision ionization processes are found to play a crucial role in determining the electron distribution and IPD for a *** IPD model is validated by reproducing latest experimental results of Al plasmas with a wide-range condition of 70 eV–700 eV temperature and 0.2–3 times solid density,as well as a typical non-LTE system of hollow Al *** is demonstrated that the present IPD model has a significant temperature dependence due to the consideration of the inelastic collision *** a lower computational cost and wider application range of plasma conditions,the proposed model is expected to provide a promising tool to study the ionization balance and the atomic processes,as well as the related radiation and particle transports properties of the WDP.

关键词： properties. collision determining

Relative exchangeable copper, a high-quality biomarker for differentiation of Traditional Chinese Medicine syndrome in Wilson's disease

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Journal of Traditional Chinese Medicine 2024年第05期44卷 1017-1023页

作者： DING Yufeng YANG Wenming CHENG Yuan YANG Yulong ZHU jun LU Yachun FANG xiang ZHANG Jing Department of Neurology the First Affiliated Hospital of Anhui University of Traditional Chinese Medicine Department of clinical laboratory the First Affiliated Hospital of Anhui University of Traditional Chinese Medicine

OBJECTIVE: To investigate the value of relative exchangeable copper(REC) in diagnosing Wilson's disease(WD) and to determine its significance in the differentiation of Traditional Chinese Medicine(TCM) ***: A total of 78 patients with WD were recruited on the same day of the medical visit, and among them,32 were suffering from non-WD(N-WD) and 37 were heterozygous ATP7B carriers(HC) enrolled as *** genetic testing was performed for diagnosing WD and HC. Additionally, REC levels in different TCM syndromes were investigated. The correlation between REC and serum ceruloplasmin(Cp), serum copper oxidase(CO), and 24-h urinary copper was analyzed using the Global Assessment Scale and Unified Wilson's Disease Rating Scale and the significance of REC in WD diagnosis was investigated. Resting-state functional magnetic resonance imaging was used to assess the clinical symptoms of WD and analyze its severity in different TCM ***: REC determination helped in significantly distinguishing patients with N-WD or HC from those with WD with a cut-off of 21.15%. Furthermore, the comparative analysis of REC ratios among different TCM syndromes showed markedly high REC levels in the dampness-heat internal accumulation syndrome ***, the seed-based functional connectivity value from the putamen to the cerebellum was significantly correlated with TCM ***: REC level is a high-quality biomarker for diagnosing WD that effectively reflects disease severity and plays an essential role in deciding on treatment strategies and prognosis. Furthermore, REC levels are closely related to TCM syndromes in WD; thus, it is a potential objective quantitative indicator for distinguishing TCM syndromes in WD.

关键词： Global Assessment Scale Traditional Chinese Medicine syndrome Wilson’s disease relative exchangeable copper the Unified Wilson’s Disease Rating Scale

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Uniformity of Asymmetric Augmented Designs

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Acta Mathematicae Applicatae Sinica 2024年第4期40卷 1025-1044页

作者： Zhi-qing WANG xiang-yu FANG Zu-jun OU College of Mathematics and Statistics Jishou UniversityJishou 416000China

Follow-up experimental designs are widely applied to explore the relationship between factors and responses step by step in various fields such as science and *** some additional resources or information become available after the initial design of experiment is carried out,some additional runs and/or factors may be added in the follow-up *** this paper,the issue of the uniform row augmented designs and column augmented designs with mixed two-,three-and four-level is *** uniformity of augmented designs is discussed under the wrap-around L_(2)-*** lower bounds of wrap-around L_(2)-discrepancy for the augmented designs are obtained,which can be used to assess uniformity of augmented *** results show that augmented designs have high efficiency,which have low discrepancy and close to the proposed lower bounds.

关键词： augmented design follow-up design uniform design wrap-around L_(2)-discrepancy

Development and Validation of a Carbohydrate Metabolism-related Model for Predicting Prognosis and Immune Landscape in Hepatocellular Carcinoma Patients

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当代医学科学（英文） 2024年第4期44卷 771-788页

作者： Hong-xiang HUANG pei-yuan ZHONG Ping LI Su-juan PENG Xin-jing DING xiang-lian CAI Jin-hong CHEN Xie ZHU Zhi-hui LU Xing-yu TAO Yang-yang LIU Li CHEN Department of Oncology The First Affiliated Hospital of Nanchang UniversityNanchang 330006China Jiangxi Institute of Respiratory Disease The First Affiliated Hospital of Nanchang UniversityNanchang 330006China Department of Oncology Jiangxi Provincial People's HospitalThe First Affiliated Hospital of Nanchang Medical CollegeNanchang 330006China Jiangxi Institute of Respiratory Disease The First Affiliated Hospital of Nanchang UniversityNanchang 330006China Department of Respiratory and Critical Care Medicine The First Affiliated Hospital of Nanchang UniversityNanchang 330006China Department of Oncology The First Affiliated Hospital of Nanchang UniversityNanchang 330006China

Objective:The activities and products of carbohydrate metabolism are involved in key processes of ***,its relationship with hepatocellular carcinoma(HCC)is ***:The cancer genome atlas(TCGA)-HCC and ICGC-LIRI-JP datasets were acquired via public *** expressed genes(DEGs)between HCC and control samples in the TCGA-HCC dataset were identified and overlapped with 355 carbohydrate metabolism-related genes(CRGs)to obtain differentially expressed CRGs(DE-CRGs).Then,univariate Cox and least absolute shrinkage and selection operator(LASSO)analyses were applied to identify risk model genes,and HCC samples were divided into high/low-risk groups according to the median risk ***,gene set enrichment analysis(GSEA)was performed on the risk model *** sensitivity of the risk model to immunotherapy and chemotherapy was also ***:A total of 8 risk model genes,namely,G6PD,PFKFB4,ACAT1,ALDH2,ACYP1,OGDHL,ACADS,and TKTL1,were ***,the risk score,cancer status,age,and pathologic T stage were strongly associated with the prognosis of HCC *** the stromal score and immune score had significant negative/positive correlations with the risk score,reflecting the important role of the risk model in immunotherapy ***,the stromal and immune scores had significant negative/positive correlations with risk scores,reflecting the important role of the risk model in immunotherapy ***,we found that high-/low-risk patients were more sensitive to 102 drugs,suggesting that the risk model exhibited sensitivity to chemotherapy *** results of the experiments in HCC tissue samples validated the expression of the risk model ***:Through bioinformatic analysis,we constructed a carbohydrate metabolism-related risk model for HCC,contributing to the prognosis prediction and treatment of HCC patients.

关键词： bioinformatics carbohydrate metabolism hepatocellular carcinoma the cancer genome atlas

Clinical characteristics of testicular torsion and factors influencing testicular salvage in children:A 12-year study in tertiary center

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World Journal of Clinical Cases 2024年第7期12卷 1251-1259页

作者： xiang-Hui Gang Yuan-Yuan Duan Bin Zhang Zheng-Gan Jiang Rong Zhang jun Chen xiang-Yu Teng Duo-Bing Zhang Department of Urology Suzhou Hospital Affiliated to Anhui Medical UniversitySuzhou 234000Anhui ProvinceChina Department of Ultrasound Diagnosis Suzhou Hospital Affiliated to Anhui Medical UniversitySuzhou 234000Anhui ProvinceChina Department of Urology The Second Affiliated Hospital of Anhui Medical UniversityHefei 230000Anhui ProvinceChina

BACKGROUND Testicular torsion is the most common acute scrotum worldwide and mainly occurs in children and *** have demonstrated that the duration of symptoms and torsion grade lead to different outcomes in children diagnosed with testicular *** To predict the possibility of testicular salvage(TS)in patients with testicular torsion in a tertiary *** We reviewed the charts of 75 pediatric patients with acute testicular torsion during a 12-year period from November 2011 to July 2023 at the Suzhou Hospital of Anhui Medical *** and multivariate logistic regression analyses were used to determine independent predictors of testicular *** data included clinical findings,physical examinations,laboratory data,color Doppler ultrasound findings,operating results,age,presenting institution status,and follow-up *** Our study included 75 *** was possible in 57.3%of all patients;testicular torsion occurred mostly in winter,and teenagers aged 11-15 years old accounted for 60%.Univariate logistic regression analyses revealed that younger age(P=0.09),body mass index(P=0.004),torsion angle(P=0.013),red blood cell count(P=0.03),neutrophil-to-lymphocyte ratio(P=0.009),and initial presenting institution(P<0.001)were associated with *** multivariate analysis,only the initial presenting institution predicted TS(P<0.05).CONCLUSION The initial presenting institution has a predictive value for predicting TS in patients with testicular *** with scrotal pain should be admitted to a tertiary hospital as soon as possible.

关键词： Testicular torsion Testicular salvage Pediatrics Predictors Case report

Neosophoflavonoids A–C, A class of highly oxidized hybrid flavonoids from Sophora flavescens with antidiabetic effects

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Chinese Chemical Letters 2024年第10期35卷 321-324页

作者： Xu Zhang Jiang Li Kai-Zhou Lu Ya-Nan Yang Jian-Shuang Jiang xiang Yuan Zi-Ming Feng Fei Ye pei-Cheng Zhang State Key Laboratory of Bioactive Substance and Function of Natural Medicines Institute of Materia Medica Chinese Academy of Medical Sciences and Peking Union Medical College

Three highly oxidized hybrid flavonoids neosophoflavonoids A–C（1, 2a, and 2b） were isolated from the roots of Sophora flavescens. Neosophoflavonoid A possesses a unique highly oxidized heptacyclic6/6/6/6/6/6/5 system. Neosophoflavonoids B and C are isomers and share the same highly oxidized hexacyclic 6/6/6/6/6/6 systems. Their planar structures were elucidated from 1D/2D nuclear magnetic resonance（NMR）, ultraviolet spectroscopy（UV）, infrared spectroscopy（IR）, and high resolution electrospray ionization mass spectroscopy（HRESIMS） data. Their absolute configurations were determined by thorough GIAO13C NMR（DP4+） calculation protocol and electronic circular dichroism（ECD） calculation *** plausible biosynthetic routes for the compounds were also proposed. All compounds exhibited significant protein tyrosine phosphatase-1B（PTP1B） inhibitory activity with half maximal inhibitory concentration(IC50) values 3.94 ± 0.01, 0.38 ± 0.13, and 0.70 ± 0.01 μmol/L, respectively. In addition, compared to a positive control fenofibrate（Feno） at 20 μmol/L, compounds 2a and 2b exhibited stronger inhibitory effects on lipid accumulation in the oleic acid（OA）-induced cell model at 5 and 10 μmol/L.

关键词： Highly oxidized hybrid flavonoids Lipid accumulation inhibition Neosophoflavonoids A–C PTP1B inhibition Sophora flavescens