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Chemical Research in Chinese Universities 2024年第4期40卷 657-663页

作者： ZHU Lixun LIU Dan WU Kaiwen XIE Guohua ZHAO zheng TANG Ben Zhong School of Science and Engineering Shenzhen Institute of Aggregate Science and TechnologyThe Chinese University of Hong KongShenzhen(CUHK-Shenzhen)Shenzhen518172P.R.China Department of Chemistry Hong Kong Branch of Chinese National Engineering Research Center for Tissue Restoration and ReconstructionThe Hong Kong University of Science and TechnologyHongkong999077P.R.China The Institute of Flexible Electronics(Future Technologies) Xiamen UniversityXiamen361005P.R.China

Developing easily accessible deep-red/near-infrared circularly polarized emitters for practical organic light-emitting diodes remains a significant ***,a practical strategy has been proposed for developing deep-red circularly polarized delayed fluorescent emitters based on a novel chiral acceptor *** changing triphenylamine(TPA)substitution position from para to meta,R/S-M-TBBTCN demonstrated thermally activated delayed fluorescence(TADF)properties with a delayed lifetime of 6.6µs that R/S-P-TBBTCN doesn’t ***,R/S-M-TBBTCN showed a 65 nm red-shift in emission and a 10-fold enhancement in asymmetry factor(glum),compared with R/*** solution-processed nondoped circularly polarized organic light-emitting diodes(CP-OLEDs)based on R-M-TBBTCN display deep-red emission and 2.2%external quantum efficiency.

关键词： Amplified chirality Deep-red circularly polarized organic light emitting-diode Binaphthol based chiral acceptor

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铁基超导涡旋演生马约拉纳零能模

物理学报 2020年第11期69卷 11-51,F0004页

作者：孔令元丁洪中国科学院物理研究所北京凝聚态物理国家研究中心北京100190 中国科学院大学物理科学学院北京100049 中国科学院大学中国科学院拓扑量子计算卓越中心北京100049

作为马约拉纳零能模(MZM)的一种全新载体,具有拓扑能带结构的铁基超导块材--拓扑铁基超导体--近年来引起了学术界的广泛关注.由于同时具备单一材料、高温超导、强电子关联、拓扑能带等特质,拓扑铁基超导体成功规避了本征拓扑超导体和近... 详细信息

作为马约拉纳零能模(MZM)的一种全新载体,具有拓扑能带结构的铁基超导块材--拓扑铁基超导体--近年来引起了学术界的广泛关注.由于同时具备单一材料、高温超导、强电子关联、拓扑能带等特质,拓扑铁基超导体成功规避了本征拓扑超导体和近邻异质结体系在实现MZM上的困难,为马约拉纳物理开辟了自赋性拓扑超导的新方向.时至今日,人们已经在多种拓扑铁基超导体的磁通涡旋中测量到了纯净的MZM.实验发现,铁基超导体系中演生的涡旋MZM信号明确、物理清晰,具有很好的应用前景.拓扑铁基超导体有望成长为研究马约拉纳物理和制备拓扑量子比特最重要的材料体系之一.本文以Fe(Te,Se)为主要对象详细介绍了铁基超导马约拉纳载体的思想起源和研究进展.在阐明Fe(Te,Se)拓扑能带结构和零能涡旋束缚态基本实验事实的基础上,本文将逻辑清晰地系统总结铁基超导涡旋演生MZM的主要实验观测和基本物理行为;借助波函数、准粒子中毒等实验,解析Fe(Te,Se)单晶中的涡旋MZM演生机制;结合现有马约拉纳理论,深入探讨铁基超导体中的马约拉纳对称性和准粒子拓扑本质的实验测量.最后,本文采用"从量子物理到量子工程"的视角,综合分析涡旋MZM在真实材料和实际实验中的鲁棒性,为未来潜在的工程应用提供有益指导.本文以物理原理为线,注重理论与实验结合,旨在搭建经典马约拉纳理论与新兴拓扑铁基超导体系之间的桥梁,帮助读者理解铁基超导涡旋中演生的MZM.

关键词：马约拉纳零能模铁基超导体超导磁通涡旋拓扑物态

Effects of Mahuang(Herba Ephedra Sinica) and Wuweizi(Fructus Schisandrae Chinensis) medicated serum on chemotactic migration of alveolar macrophages and inters regions macrophages in rats

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Journal of Traditional Chinese Medicine 2017年第5期37卷 607-615页

作者： Yuan Yiping Zhai Huaqiang Zhang Tian Guo Zhaojuan kong Liting Jia Xiaoyu Wang Ningning Dai Ying Liu Guoxiu Wang Yanping Department of Clinical Chinese Pharmacy School of Chinese Materia Medica Beijing University of Chinese Medicine Department of Pharmacy Beijing Hospital Institute of Clinical Basic Medicine of Traditional Chinese Medicine Chinese Academy of Traditional Chinese Medicine

OBJECTIVE: To observe the effects of serum containing Mahuang(Herba Ephedra Sinica) or Wuweizi(Fructus Schisandrae Chinensis) on the migration of alveolar macrophages(AM) and interstitial macrophages(IM) from normal rats, and to analyze and compare the mechanisms leading to cell migration ***: Rats were randomly divided into three groups: Mahuang(Herba Ephedra Sinica), Wuweizi(Fructus Schisandrae Chinensis), and blank serum. After treatment with the herbs, serum was extracted from the rats. AM and IM were isolated from normal rats and cultured. The effects of Mahuang(Herba Ephedra Sinica) and Wuweizi(Fructus Schisandrae Chinensis) medicated serum on normal rat AM and IM chemotactic migration were determined by transwell assays. The CC chemokine receptor(CCR) 2, CCR5, voltage-gated Kvl. 3 K^+channel(Kv1. 3), and voltage-gated Kvl. 5 K^+channel(Kv1. 5) protein levels were analyzed by western ***: The migration quantities of AM and IM in the Mahuang(Herba Ephedra Sinica) and Wuweizi(Fructus Schisandrae Chinensis) medicated serum groups were significantly higher than those in the blank serum group(P < 0.01). Compared with the Wuweizi(Fructus Schisandrae Chinensis) medicated serum group, the migration quantity of cultured rat AM in the Mahuang(Herba Ephedra Sinica) medicated serum group was significantly increased(P <0.01). Meanwhile, compared with the Mahuang(Herba Ephedra Sinica) medicated serum group, the migration quantity of cultured rat IM in the Wuweizi(Fructus Schisandrae Chinensis) medicated serum group was significantly increased(P < 0.01).CCR2, CCR5, Kv1. 3, and Kv1. 5 proteins were expressed on the AM cell surface, and showed significantly higher expression in the Mahuang(Herba Ephedra Sinica) medicated serum group compared with the Wuweizi(Fructus Schisandrae Chinensis)medicated serum group. In contrast, CCR5, Kv1.3,and Kv1.5 proteins were expressed on the IM cell surface, and showed significantly higher expression in the Wuweizi

关键词： Ephedra sinica Schisandra Chinensis Macrophage Receptors CCR Delayed rectifier po tassium channel Chemotaxis

Mosquito densovirus signifcantly reduces the vector susceptibility to dengue virus serotype 2 in Aedes albopictus mosquitoes(Diptera:Culicidae)

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Infectious Diseases of Poverty 2023年第3期12卷 91-92页

作者： Ling kong Jie Xiao Lu Yang Yuan Sui Duoquan Wang Shaoqiang Chen Peiwen Liu Xiao-Guang Chen Jinbao Gu Guangdong Provincial Key Laboratory of Tropical Disease Research Depart-ment of Pathogen BiologySchool of Public HealthSouthern Medical Uni-versityGuangzhou 510515GuangdongChina Brown School Washington UniversitySt.LouisMO 63130USA National Institute of Parasitic Diseases Chinese Center for Disease Control and PreventionShanghai 200025China Shenzhen Aiming Pest Control Operation Service Company Limited Shenz-henGuangdongChina

Background Dengue virus(DENV)is a major public health threat,with Aedes albopictus being the confrmed vector responsible for dengue epidemics in Guangzhou,*** densoviruses(MDVs)are pathogenic mosquitospecifc viruses,and a novel MDV was previously isolated from *** in *** study aims to determine the prevalence of MDVs in wild *** populations and investigate their potential interactions with DENV and impact on vector susceptibility for *** The prevalence of MDV in wild mosquitoes in China was investigated using open access sequencing data and PCR detection in *** in *** viral infection rate and titers in MDV-persistent C6/36 cells were evaluated at 12,24,48,72,96,and 120 h post infection(hpi)by indirect immunofuorescence assay(IFA)and real time quantitative PCR(RT-qPCR).The midgut infection rate(MIR),dissemination rate(DR),and salivary gland infection rate(SGIR)in various tissues of MDV-infected mosquitoes were detected and quantifed at 0,5,10,and 15 days post infection(dpi)by RT-PCR and *** chi-square test evaluated dengue virus serotype 2(DENV-2)and Aedes aegypti densovirus(AaeDV)infection rates and related indices in mosquitoes,while Tukey’s LSD and t-tests compared viral titers in C6/36 cells and tissues over *** The results revealed a relatively wide distribution of MDVs in Aedes,Culex,and Anopheles mosquitoes in China and an over 68%positive *** vitro,signifcant reductions in DENV-2 titers in supernatant at 120 hpi,and an appar‑ent decrease in DENV-2-positive cells at 96 and 120 hpi were *** vivo,DENV-2 in the ovaries and salivary glands was frst detected at 10 dpi in both monoinfected and superinfected *** females,while MDV super‑infection with DENV-2 suppressed the salivary gland infection rate at 15 ***-2 titer in the ovary and salivary glands of *** was reduced in superinfected mosquitoes at 15 *** MDVs is widespread in nat

关键词： DENV-2 Mosquito densovirus Superinfection Aedes albopictus Vector susceptibility

Advances in Transdermal Drug Delivery for Cancer Therapy

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Journal of Clinical and Nursing Research 2024年第8期8卷 175-182页

作者： Ziye Lin Ming kong Ocean University of China Qingdao 266100Shandong ProvinceChina

Transdermal drug delivery offers a promising alternative to traditional cancer therapies by providing a non-invasive,controlled,and targeted delivery of therapeutic *** paper explores the advancements,benefits,and challenges associated with transdermal drug delivery systems(TDDS)in cancer *** highlights the mechanisms of action,key technologies,and the potential impact on patient *** examining recent studies and clinical trials,this paper aims to provide a comprehensive overview of the efficacy,safety,and prospects of transdermal drug delivery in oncology.

关键词： Transdermal drug delivery Cancer therapy Chemotherapy

用有限元求导法计算VLSI中工艺变化的互连线寄生电容

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电工电能新技术 2008年第3期27卷 40-43页

作者：屈慧任卓翔孔力中国科学院电工研究所北京100190 Mentor Graphics Corporation San JoseCA 95131USA

集成电路发展到当前纳米级的工艺水平,互连线的宽度已经远低于掩膜光刻工艺中所使用的光波长,使光刻后互连线的外形与设计尺寸不一致,其中一个重要特征就是导线边角圆化,这给准确提取互连线的寄生参数带来了困难。本文运用有限元求导的... 详细信息

集成电路发展到当前纳米级的工艺水平,互连线的宽度已经远低于掩膜光刻工艺中所使用的光波长,使光刻后互连线的外形与设计尺寸不一致,其中一个重要特征就是导线边角圆化,这给准确提取互连线的寄生参数带来了困难。本文运用有限元求导的方法,求出互连线寄生电容对于其边角尺寸的敏感度,为设计后期电容的准确提取和分析提供支持。算例表明,这种方法计算出的电容完全满足工程上的精度要求,可以成为集成电路设计的一个辅助工具。

关键词： VLSI 互连寄生参数敏感度工艺变化

Experience of donor right lobe hepatectomy in adult-to-adult live donor liver transplantation: clinical analysis of 89 cases

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Hepatobiliary & Pancreatic Diseases International 2002年第2期1卷 166-171页

作者： Sheung-Tat Fan Chung-Mau Lo Chi-Leung Liu From the Centre for the Study of Liver Disease and Department of Surgery, University of Hong kong Medical Centre, Queen Mary Hospital, Hong kong, China Centre for the Study of Liver Disease and Department of Surgery University of Hong Kong Medical Centre Queen Mary Hospital Hong Kong China. hrmsfst@hkucc.hku.hk

Objective: To review the experience of donor selec- tion and right lobe hepatectomy in adult-to-adult live donor liver transplantation. Methods: From May 1996 to December 2001, 89 live donor liver transplants using right lobe grafts were performed at Queen Mary Hospital, Hong kong. All donors had received psychological counseling before donor operations. They were screened by laboratory tests including complete blood cell count, liver and renal biochemistry, and viral serology studies. Com- puted tomography (CT), CT volumetry and hepatic arteriography were routinely performed. All donors underwent the operations using the method designed by us. Results: The median duration of the operations was 8.8 hours. The median blood loss recorded 466 ml. The median intensive care unit and hospital stays were 2 and 10 days, respectively. There was no do- nor mortality. Complications of donor operations in- cluded wound infection, urinary tract infection, bili- ary stricture, cholestasis, subphrenic collection, bowel obstruction and incision hernia, etc. All do- nors have recovered and returned to their previous occupations. Conclusions: Live donation of right lobe grafts for a- dult-to-adult liver transplantation is safe, provided that donor selection is strict and utmost care is exer- cised during the operation.

关键词： right lobe graft liver transplantation hepstectomy

Analysis of the Current Situation of Active Pharmaceutical Ingredient (API) Export in China

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Asian Journal of Social Pharmacy 2019年第3期14卷 126-134页

作者： kong Deqiang Dong Li School of Business Administration Shenyang Pharmaceutical University Shenyang 110016 China

Objective To analyze the problems of API export in China and to study the current international and domestic trading environment. Methods Data statistical analysis was used to study the export situation of APIs, and PEST was applied to analyze the current export problems. Results and Conclusion API export in China is now experiencing a growth period and the international trading environment is constantly improving.

关键词： active pharmaceutical ingredient (API) export trade environmental analysis

Occurrence and Reduction of Hepatitis B Vaccine Hesitancy Among Medical University Students—Shanxi Province,China,2020

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China CDC weekly 2024年第19期6卷 431-436,I0005-I0007页

作者： Huijuan kong Xufeng Cui Ying Zhang Qiang Xue Jing Shi Tian Yao Yana Guo Xiuyang Xu Suping Wang Yongliang Feng School of Public Health Shanxi Medical UniversityTaiyuan CityShanxi ProvinceChina Center of Clinical Epidemiology and Evidence Based Medicine Shanxi Medical UniversityTaiyuan CityShanxi ProvinceChina Key Laboratory of Coal Environmental Pathogenicity and Prevention(Shanxi Medical University) Ministry of EducationTaiyuan CityShanxi ProvinceChina First Hospital/First Clinical Medical College of Shanxi Medical University Taiyuan CityShanxi ProvinceChina

Summary What is already known about this topic?Previous research has primarily examined the issue of hepatitis B vaccine hesitancy in migrant workers and other adult ***,there is a lack of studies that have specifical... 详细信息

关键词： Shanxi primarily workers

基岩厚度与岩性对关键层破断的影响与力学分析

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煤炭技术 2009年第11期28卷 39-42页

作者：孔翔黄军碗黄金中国矿业大学"煤炭资源与安全开采"国家重点实验室江苏徐州221008 中国矿业大学矿业工程学院江苏徐州221116

利用数值模拟工具,研究了不同厚度与岩性的基岩对关键层破断的影响。由此提出净载荷的概念,并在此基础上对模拟结果进行曲线拟合和力学建模分析。数值模拟结果表明,相同基岩厚度时,岩性越硬,关键层破断时所对应的开采步距kp越大;相同岩... 详细信息

利用数值模拟工具,研究了不同厚度与岩性的基岩对关键层破断的影响。由此提出净载荷的概念,并在此基础上对模拟结果进行曲线拟合和力学建模分析。数值模拟结果表明,相同基岩厚度时,岩性越硬,关键层破断时所对应的开采步距kp越大;相同岩性条件下,基岩越厚,对应的kp也越大。力学分析发现,基岩的厚度与岩性对关键层的净载荷分布有显著影响,由此而导致关键层弯曲破断行为的差异。

关键词：关键层破断净载荷数值模拟力学分析