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The neuroprotective effects of oxygen therapy in Alzheimer’s disease:a narrative review

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Neural Regeneration Research 2023年第1期18卷 57-63页

作者： Cui yang Qiu yang yang xiang Xian-Rong Zeng Jun Xiao Wei-Dong Le School of Medicine University of Electronic Science and Technology of ChinaChengduSichuan ProvinceChina Institute of Neurology Sichuan Provincial People’s HospitalUniversity of Electronic Science and Technology of ChinaChengduSichuan ProvinceChina Chinese Academy of Sciences Sichuan Translational Medicine Research Hospital ChengduSichuan ProvinceChina Department of Hyperbaric Oxygen Sichuan Provincial People’s HospitalUniversity of Electronic Science and Technology of ChinaChengduSichuan ProvinceChina Sichuan Provincial Center for Mental Health Sichuan Academy of Medical Sciences&Sichuan Provincial People’s HospitalChengduSichuan ProvinceChina

Alzheimer’s disease(AD)is a degenerative neurological disease that primarily affects the *** therapy is the main strategy for AD treatment,but current treatments suffer from poor efficacy and a number of side ***-drug therapy is attracting more attention and may be a better strategy for treatment of *** is one of the important factors that contribute to the pathogenesis of *** cellular processes synergistically promote hypoxia,including aging,hypertension,diabetes,hypoxia/obstructive sleep apnea,obesity,and traumatic brain *** evidence has shown that hypoxia may affect multiple pathological aspects of AD,such as amyloid-beta metabolism,tau phosphorylation,autophagy,neuroinflammation,oxidative stress,endoplasmic reticulum stress,and mitochondrial and synaptic *** targeting hypoxia may delay or mitigate the progression of *** studies have shown that oxygen therapy could improve the risk factors and clinical symptoms of *** evidence also suggests that oxygen therapy may improve many pathological aspects of AD including amyloid-beta metabolism,tau phosphorylation,neuroinflammation,neuronal apoptosis,oxidative stress,neurotrophic factors,mitochondrial function,cerebral blood volume,and protein *** this review,we summarized the effects of oxygen therapy on AD pathogenesis and the mechanisms underlying these *** expect that this review can benefit future clinical applications and therapy strategies on oxygen therapy for AD.

关键词： Alzheimer’s disease amyloid-beta metabolism clinical symptoms hypoxia neuroinflammation neuronal apoptosis oxygen therapy pathogenesis risk factor tau phosphorylation

Modeling dependence based on mixture copulas and its application in risk management

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Applied Mathematics(A Journal of Chinese Universities) 2009年第4期24卷 393-401页

作者： OUyang Zi-sheng LIAO Hui yang xiang-qun School of Information Hunan University of Commerce Changsha 410205 China School of Mathematics Hunan Normal University Changsha 410081 China

This paper is concerned with the statistical modeling of the dependence structure of multivariate financial data using the copula, and the application of copula functions in VaR valuation. After the introduction of the pure copula method and the maximum and minimum mixture copula method, authors present a new algorithm based on the more generalized mixture copula functions and the dependence measure, and apply the method to the portfolio of Shanghai stock composite index and Shenzhen stock component index. Comparing with the results from various methods, one can find that the mixture copula method is better than the pure Gaussian copula method and the maximum and minimum mixture copula method on different VaR level.

关键词： Gaussian mixture copula value-at-risk dependence back-test Spearman's rho

Joint Power and Duty-Cycle Design Using Alternating Optimization Algorithm under Energy Harvesting Architectures

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China Communications 2020年第12期17卷 139-155页

作者： Tong Wang xiang yang Feng Deng Lin Gao Yufei Jiang Zhihua yang School of Electronics and Information Engineering Harbin Institute of TechnologyShenzhen 518055China Shenzhen Institute of Artificial Intelligence and Robotics for Society Shenzhen 518129China

In the emerging sixth generation(6G)communication network,energy harvesting(EH)is a promising technology to achieve the unlimited energy supply and hence makes the wireless communication systems self-sustainable in terms of ***,in practice,the efficiency of energy harvesting is often low due to the limited device *** this paper,we formulate three types of different EH architectures,i.e.,the harvest-use architecture,the harvest-store-use architecture,and the harvest-use-store architecture from the perspective of energy storage *** propose resource allocation schemes to jointly design the sensor power and duty-cycle via an alternating optimization algorithm under the above EH architectures,in both simultaneous and non-simultaneous harvesting and utilization models,aiming at achieving a higher throughput and energy ***-ideal circuit power is also *** results show that our proposed schemes under EH architectures outperform the existing classic continuous transmission schemes.

关键词： resource allocation alternating optimization energy harvesting self-sustainable

Localization of s-Wave and Quantum Effective Potential of a Quasi-free Particle with Position-Dependent Mass

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Communications in Theoretical Physics 2006年第5X期46卷 819-825页

作者： JU Guo-Xing xiang yang REN Zhong-Zhou Department of Physics Nanjing University Nanjing 210093 China

The properties of the 8-wave for a quasl-free partide with position-dependent mass （PDM） have been discussed in details. Differed from the system with constant mass in which the localization of the s-wave for the free quantum particle around the origin only occurs in two dimensions, the quasi-free particle with PDM can experience attractive forces in D dimensions except D = 1 when its mass function satisfies some conditions. The effective mass of a particle varying with its position can induce effective interaction, which may be attractive in some cases. The analytical expressions of the eigenfunctions and the corresponding probability densities for the 8-waves of the two- and three-dimensional systems with a special PDM are given, and the existences of localization around the origin for these systems are shown.

关键词： position-dependent mass s-wave Schrodinger equation dimensionality of the space localization eigenfunction probability density

CO2 emission of urban passenger transportation in China from 2000 to 2014

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Advances in Climate Change Research 2019年第1期10卷 59-67页

作者： YUAN Rui-Qiang TAO Xin yang xiang-Long School of Environment and Resources Shanci UniversitTaiyuan030006China

This study reviewed the urban passenger transportation(UPT)development of seven typical cities in China from 2000 to 2014,estimated the UPT CO2emission,analyzed the structure,and discussed the main factors of UPT CO,*** showed that increases of GDP,population,and UPT scale of the cities have speeded *** most significant development of UPT is that the growth of private vehicles is greatly faster than that of public *** total and per-capita UPT CO2 emissions both *** share of private vehicles emission to total UPT CO2emission has increased,with the share in range of 65%-88%in 2014,exponentially leading to the increases of total and per-capita UPT CO2 *** UPT CO2 emission structure with more share of public transportation would slow down the UPT CO2emission increase,private vehicle CO2 emission is recognized as the dominated driving *** of driving factors,such as GDP,population,private vehicle CO2 emissions,to UPT CO2 emission are different among the *** vehicle CO2 *** the dominated factor for UPT CO2emission in Beijing and *** private vehicle CO2emission,GDP also plays an important role in UPT CO2emissions of Chengdu,Shanghai,Guangzhou,and *** of private vehicle CO2 emission and GDP to UPT CO2 emission are almost same in Xi'an.

关键词： Urban passenger transport CO2 emissions Low-carbon transport China

Catalytic ozonation-biological coupled processes for the treatment of industrial wastewater containing refractory chlorinated nitroaromatic compounds

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2010年第3期11卷 177-189页

作者： Bing-zhi LI xiang-yang XU Liang ZHU Department of Environmental Engineering College of Environmental and Resource Sciences Zhejiang University Hangzhou 310029 China

A treatability study of industrial wastewater containing chlorinated nitroaromatic compounds （CNACs） by a catalytic ozonation process （COP） with a modified Mn/Co ceramic catalyst and an aerobic sequencing batch reactor （SBR） was investigated. A preliminary attempt to treat the diluted wastewater with a single SBR resulted in ineffective removal of the color, ammonia, total organic carbon （TOC） and chemical oxygen demand （COD）. Next, COP was applied as a pretreatment in order to obtain a bio-compatible wastewater for SBR treatment in a second step. The effectiveness of the COP pretreatment was assessed by evaluating wastewater biodegradability enhancement （the ratio of biology oxygen demand after 5 d （BOD5） to COD）, as well as monitoring the evolution of TOC, carbon oxidation state （COS）, average oxidation state （AOS）, color, and major pollutant concentrations with reaction time. In the COP, the catalyst preserved its catalytic properties even after 70 reuse cycles, exhibiting good durability and stability. The performance of SBR to treat COP effluent was also examined. At an organic loading rate of 2.0 kg COD/（m^3.d）, with hydraulic retention time （HRT）=10 h and temperature （30±2） ℃, the average removal efficiencies of NH3-N, COD, BOD5, TOC, and color in a coupled COP/SBR process were about 80%, 95.8%, 93.8%, 97.6% and 99.3%, respectively, with average effluent concentrations of 10 mg/L, 128 mg/L, 27.5 mg/L, 25.0 mg/L, and 20 multiples, respectively, which were all consistent with the national standards for secondary discharge of industrial wastewater into a public sewerage system （GB 8978-1996）. The results indicated that the coupling of COP with a biological process was proved to be a technically and economically effective method for treating industrial wastewater containing recalcitrant CNACs.

关键词： Industrial wastewater Catalytic ozonation Sequencing batch reactor Chlorinated nitroaromatic compounds

Spatial distribution of soil hydraulic parameters estimated by pedotransfer functions for the Jialing River Catchment,Southwestern China

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Journal of Mountain Science 2016年第1期13卷 29-45页

作者： LEI Wen-Juan TANG xiang-Yu Brian J.REID ZHOU xiang-yang Key Laboratory of Mountain Surface Processes and Ecological Regulation Institute of Mountain Hazards and EnvironmentChinese Academy of SciencesChengdu 610041China University of Chinese Academy of Sciences Beijing 100049China School of Environmental Sciences University of East AngliaNorwich NR4 7T JUK College of Water Resource&Hydropower University of SichuanChengdu 610065China

Soil hydraulic parameters θs,α,n,Ks,L and θr of the van Genuchten-Mualem model were estimated using three pedotransfer functions(PTFs) based on soil properties for surface soils of the largest main tributary catchment(the Jialing River) of the upper yangtze River in *** soil database was from the second national soil survey of China with a spatial 30 × 30 arc-second *** to the statistical analysis of the differences between the continuous-PTFs-estimated values of soil hydraulic parameters for the study catchment and the reference values for a specific texture class provided in the development database of a specific PTF,best estimations were obtained using the W?sten *** Rawls & Brakenssiek PTF was good estimation for parameter θr that was assumed as zero by W?sten *** established higher θr(0.08%) and lower Ks(20 cm/d) and θs(0.43%) in the mid-downstream area relative to the other areas of the catchment could lead to larger amounts of surface runoff andconsequently provide higher energy to erode ***,these factors provide a supporting explanation for previously reported severe soil erosion occurring in this *** heterogeneity analysis for estimated hydraulic parameters in terms of semivariogram showed that the spatial correlation distance was in the range of 50-80 km and that the spatial variability(sill) was not large except for parameters Ks and *** semi-variance with the exponential model at the zero distance(nugget) was 30%-50% of the *** study provided a practical PTF approach for estimating soil hydraulic properties from soil survey data at a large watershed *** estimation results could provide better insight into the mechanism of surface runoff and soil erosion,which is important to better understand and manage erosion in the catchment.

关键词： hydraulic catchment erosion downstream runoff texture exponential heterogeneity watershed fitted

Quantification and timing of porosity evolution in tight sand gas reservoirs:an example from the Middle Jurassic Shaximiao Formation,western Sichuan,China

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Petroleum Science 2015年第2期12卷 207-217页

作者： Zheng-xiang Lü Su-Juan Ye xiang yang Rong Li Yuan-Hua Qing State Key Laboratory of Oil and Gas Reservoir Geology &Exploitation Chengdu University of Technology Exploration and Production Research Institute Sinopec Southwest Chengdu Institute of Geology and Mineral Resources PetroChina Tarim Oilfield Company

The diagenesis and porosity evolution of the Middle Jurassic Shaximiao sandstones were analyzed based on petrographic observations, X-ray diffractometry, scanning electron microscopy observations, carbon and oxygen stable isotope geochemistry, fluid inclusion mi- crothermometry, and thermal and burial history modeling results. The point count data show that secondary pores （av. 5.5 %） are more abundant than primary pores （av. 3.7 %） and are thus the dominant pore type in the Shaximiao sandstones. Analysis of porosity evolution indicates that alteration of sandstones mainly occurred during two paragenetic stages. Mechanical compaction and cementa- tion by early chlorite, calcite, and quartz typically decrease the depositional porosity （40.9 %） by an average of 37.2 %, leaving porosity of 3.7 % after stage I （〈85 ℃, 175-145 Ma）. The original intergranular porosity loss due to compaction is calculated to be 29.3 %, suggesting that mechanical compaction is the most significant diagenetic process in primary porosity destruction. Stage II can be further divided into two sub-stages （Stage IIa and Stage IIb）. Stage IIa （85-120 ℃, 145-125 Ma） is characterized by late dissolution, which enhanced porosity by 8.8 %, and the porosity increased from 3.7 % to 12.5 %. During stage IIb （〉120 ℃, 125-0 Ma）, the precipitation of late chlorite, calcite, quartz, and kaolinite destroyed 3.3 % porosity, leaving porosity of 9.2 % in the rock today.

关键词： Diagenesis Porosity evolution -Tight gas sandstones Jurassic Western Sichuan

Corrosion Performance of High Strength 15Cr Martensitic Stainless Steel in Severe Environments

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Journal of Iron and Steel Research International 2014年第8期21卷 774-780页

作者： xiang-hong L Fu-xiang ZHANG xiang-tong yang Jun-feng XIE Guo-xian ZHAO Yan XUE School of Materials Science and Engineering Xi'an Shiyou University Petroleum Engineering Institute Petrochina Tarim Oilfield Company Xi'an Maurer Petroleum Engineering Laboratory Co.Ltd.

High pressure and high temperature corrosion performance of high strength 15 Cr martensitic stainless steel was studied in different severe environments—live acid（10%HCl＋1.5%HF＋3%HAc＋5.1% corrosion inhibitor）,spent acid and formation water containing *** results show that the corrosion of high strength 15 Cr martensitic stainless steel in live acid is most serious,and the uniform corrosion rate is far greater than those in spent acid and formation water containing CO2 corrosion environments,but all of them can be acceptable for *** corrosion inhibitor displays a good matching ability with the high strength 15 Cr martensitic stainless steel in terms of decreasing the uniform corrosion rate,which changes mainly the anodic process of high strength 15 Cr martensitic stainless *** corrosion potential moves to the positive direction,thus the corrosion current density decreases *** are some different degrees of pitting of high strength 15 Cr martensitic stainless steel after corrosion tests in live acid,spent acid and formation water containing CO2,and the pitting density aggravates significantly and the maximum pit depth decreases in the corrosion sequence.

关键词： high strength 15Cr martensitic stainless steel live acid spent acid CO2 corrosion