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Advancements and challenges in bionic joint lubrication biomaterials for sports medicine

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BIOSURFACE AND BIOTRIBOLOGY 2024年第3期10卷 89-105页

作者： xiang, lei Wang, Zhen Cui, Wenguo Shanghai Jiao Tong Univ Shanghai Inst Traumatol & Orthopaed Shanghai Key Lab Prevent & Treatment Bone & Joint Dept OrthopaedRuijin HospSch Med Shanghai Peoples R China

Bionic lubricant materials are a class of materials inspired by natural organisms and offer excellent lubrication properties and biocompatibility. In the field of sports medicine, their application opens up new possibilities for the prevention and treatment of sports-related diseases. The authors will introduce the existing theoretical models of friction in the locomotor system, the characteristics and advantages of biomimetic lubrication materials and discuss in depth their applications in the field of sports medicine. The development of bionic lubrication materials opens up unprecedented opportunities for sports medicine to provide more effective and long-lasting treatment options for patients.

关键词： biointerface bio-lubricant biomaterials biomedical application medicine FLEXOR TENDON REPAIR SYNOVIAL-FLUID BOUNDARY LUBRICATION SURFACE MODIFICATION ARTICULAR-CARTILAGE MOLECULAR-STRUCTURE GLIDING RESISTANCE OSTEOARTHRITIS LUBRICIN PREVENTION

Dynamic Analysis of A Deepwater Drilling Riser with A New Hang-off System

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China Ocean Engineering 2024年第1期38卷 29-41页

作者： LI Yan-wei LIU Xiu-quan WANG Jin-long CHEN Guo-ming CHANG Yuan-jiang SHENG lei-xiang Centre for Offshore Engineering and Safety Technology China University of PetroleumQingdao 266580China National Engineering Laboratory of Offshore Geophysical and Exploration Equipment China University of PetroleumQingdao 266580China China CNOOC Research Institute Co. Ltd.Beijing 100028China

The safety of risers in hang-off states is a vital challenge in offshore oil and gas engineering.A new hang-off system installed on top of risers is proposed for improving the security of *** approach leads to a challenging problem:coupling the dynamics of risers with a new hang-off system combined with multiple structures and complex *** accurately analyze the dynamic responses of the coupled system,a coupled dynamic model is established based on the Euler-Bernoulli beam-column theory and penalty function method.A comprehensive analysis method is proposed for coupled dynamic analysis by combining the finite element method and the Newmarkβ*** analysis program is also developed in MATLAB for dynamic *** simulation results show that the dynamic performances of the risers at the top part are significantly improved by the new hang-off system,especially the novel design,which includes the centralizer and articulation *** bending moment and lateral deformation of the risers at the top part decrease,while the hang-off joint experiences a great bending moment at the bottom of the lateral restraint area which requires particular attention in design and *** platform navigation speed range under the safety limits of risers expands with the new hang-off system in use.

关键词： deepwater drilling riser new hang-off system dynamic analysis finite element method penalty function method

Alanine aminotransferase as a risk marker for new-onset metabolic dysfunction-associated fatty liver disease

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World Journal of Gastroenterology 2024年第25期30卷 3132-3139页

作者： Di Wang Bing-Yan Zhou lei xiang Xu-Yong Chen Jie-Xiong Feng Department of Pediatric Surgery Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030Hubei ProvinceChina

In this editorial,we comment on the article by Chen et *** dysfunction-associated fatty liver disease(MAFLD)is a global public health burden whose incidence has risen concurrently with overweight and *** its detri-mental health impact,early identification of at-risk individuals is *** diagnosis is based on evidence of hepatic steatosis indicated by liver biopsy,imaging,or blood biomarkers,and one of the following conditions:Overweight/obesity,type 2 diabetes mellitus,or metabolic ***,in large-scale epidemiological studies,liver biopsies are not *** application of techniques such as ultrasonography,computed tomography,magnetic resonance imaging,and magnetic resonance spectroscopy is restricted by their limited sensitivity,low effectiveness,high costs,and need for specialized *** biomarkers offer several advantages,particularly in large-scale epidemiological studies or clinical scenarios where traditional imaging techniques are *** of cumulative effects of excess high-normal blood alanine aminotrans-ferase(ALT)levels of blood ALT levels could facilitate identification of at-risk patients who might not be detected through conventional imaging ***,investigating the utility of blood biomarkers in MAFLD should enhance early detection and monitoring,enabling timely inter-vention and management and improving patient outcomes.

关键词： Nonalcoholic fatty liver disease Metabolic dysfunction-associated fatty liver disease Alanine aminotransferase Screening Risk marker

Molecular phylogeny and taxonomy of Phlomoides(Lamiaceae subfamily Lamioideae)in China:Insights from molecular and morphological data

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Plant Diversity 2024年第4期46卷 462-475页

作者： Yue Zhao Ya-Ping Chen Bryan T.Drew Fei Zhao Maryam Almasi Orzimat T.Turginov Jin-Fei Xiao Abdul G.Karimi Yasaman Salmaki xiang-Qin Yu Chun-lei xiang CAS Key Laboratory for Plant Diversity and Biogeography of East Asia Kunming Institute of BotanyChinese Academy of SciencesKunming 650201YunnanChina Ministry of Education Key Laboratory of Ecology and Resource Use of the Mongolian Plateau&Inner Mongolia Key Laboratory of Grassland Ecology School of Ecology and EnvironmentInner Mongolia UniversityHohhot 010000Inner MongoliaChina Department of Biology University of Nebraska at KearneyKearneyNE 68849USA CAS Key Laboratory of Mountain Ecological Restoration and Bioresource Utilization&Ecological Restoration and Biodiversity Conservation Key Laboratory of Sichuan Province Chinese Academy of SciencesChengdu Institute of BiologyChengdu 610042SichuanChina Center of Excellence in Phylogeny of Living Organisms Department of Plant ScienceCollege of ScienceUniversity of TehranP.O.Box 14155-6455TehranIran Institute of Botany Academy of Sciences of the Republic of UzbekistanTashkent 100047Uzbekistan Faculty of Biology Department of Botany and Plant PhysiologyNational University of Uzbekistan named after Mirzo UlugbekTashkent 100174Uzbekistan Faculty of Pharmacy Kabul University1006 KabulAfghanistan

Phlomoides,with 150-170 species,is the second largest and perhaps most taxonomically challenging genus within the subfamily Lamioideae(Lamiaceae).With about 60 species,China is one of three major biodiversity centers of *** some Phlomoides species from China have been included in previous molecular phylogenetic studies,a robust and broad phylogeny of this lineage has yet to be ***,given the myriad new additions to the genus,the existing infrageneric classification needs to be evaluated and ***,we combine molecular and morphological data to investigate relationships within Phlomoides,with a focus on Chinese *** observed that plastid DNA sequences can resolve relationships within Phlomoides better than nuclear ribosomal internal and external transcribed spacer regions(nrITS and nrETS).Molecular phylogenetic analyses confirm the monophyly of Phlomoides,but most previously defined infrageneric groups are not *** addition,morphological analysis demonstrates the significant taxonomic value of eight characters to the *** on our molecular phylogenetic analyses and morphological data,we establish a novel section Notochaete within Phlomoides,and propose three new combinations as well as three new *** study presents the first molecular phylogenetic analyses of Phlomoides in which taxa representative of the entire genus are included,and highlights the phylogenetic and taxonomic value of several morphological characters from species of Phlomoides from *** study suggests that a taxonomic revision and reclassification for the entire genus is necessary in the future.

关键词： Lamioideae Molecular phylogenetics Morphology Phlomideae Taxonomy

Exploring non-curative endoscopic submucosal dissection:Current treatment optimization and future indication expansion

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World Journal of Gastroenterology 2024年第9期30卷 1257-1260页

作者： Yi-Nong Zhu xiang-lei Yuan Wei Liu Yu-Hang Zhang Yi Mou Bing Hu Lian-Song Ye Department of Gastroenterology and Hepatology West China HospitalSichuan UniversityChengdu 610041Sichuan ProvinceChina

The increasing popularity of endoscopic submucosal dissection(ESD)as a treatment for early gastric cancer has highlighted the importance of quality assessment in achieving curative *** article emphasizes the significance of evaluating ESD quality,not only for curative cases but also for non-curative *** assessment relies on the endoscopic curability(eCura)classification,but management strategies for eCuraC-1 tumour with a positive horizontal margin are *** research primarily focuses on comparing additional surgical procedures in high-risk patients,while studies specifically targeting eCuraC-1 patients are *** management strategies and follow-up outcomes for such cases could provide valuable ***,the application of molecular imaging using near-infrared fluorescent tracers holds promise for precise tumour diagnosis and navigation,potentially impacting the management of early-stage gastric cancer *** research in these areas is essential for improving the overall efficacy of endoscopic techniques and refining treatment indications.

关键词： Early gastric cancer Endoscopic submucosal dissection Quality control Noncurative endoscopic submucosal dissection Near-infrared fluorescent tracer

Coexistence of adeno-associated virus 2 with adenovirus 18 or herpesvirus may be associated with severe lingual papillomatosis in an immunocompromised individual

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Virologica Sinica 2024年第4期39卷 705-707页

作者： Jie-Mei Yu Ze-Yin Liang Yuan-Hui Fu xiang-lei Peng Yan-Peng Zheng Yu-Jun Dong Jin-Sheng He College of Life Sciences and Bioengineering Beijing Jiaotong UniversityBeijing100044China Department of Hematology Peking University First HospitalBeijing100034China

Dear Editor,Patients undergoing allogeneic hematopoietic stem cell transplantation(HSCT)often experience a significant reduction in immune function due to factors such as severe lymphopenia,immunosuppressive treatment,and the development of graft-versus-host disease,rendering them more susceptible to severe infections(Sahin et al.,2016).Traditional diagnostic approaches are limited in sensitivity,speed,and assay targets,thus failing short of meeting the diagnostic demands(Qu et al.,2022).However,next-generation sequencing(NGS)has greatly improved the accuracy and efficiency of diagnosing various diseases(Schuler et al.,2022),and has been widely utilized for pathogen detection in samples from HSCT patients(Armstrong et al.,2019;Peng et al.,2021).In this study,we employed viral metagenomics analysis using high-throughput sequencing on fecal and tissue samples from a patient with HSCT experiencing severe lingual papillomatosis.

关键词： al. papilloma rendering

The future path to sutureless surgery:Self–adhesive tough hydrogel

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Science Bulletin 2024年第15期69卷 2307-2310页

作者： lei xiang Ding Zhao Yihan Li Qimanguli Saiding Wenguo Cui Department of Orthopaedics Shanghai Key Laboratory for Prevention and Treatment of Bone and Joint DiseasesShanghai Institute of Traumatology and OrthopaedicsRuijin HospitalShanghai Jiao Tong University School of MedicineShanghai 200025China

Surgical sutures serve as foundational elements in surgical procedures,facilitating wound closure,exudation minimization,infection prevention,structural support maintenance,and healing *** classification of traditional surgical suturing methods is intricate,and contingent upon variables such as tissue type,wound morphology,and desired healing outcomes.

关键词： healing wound prevention

Three-dimensional magnetic reconnection in complex multiple X-point configurations in an ancient solar-lunar terrestrial system

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Chinese Physics B 2024年第3期33卷 488-495页

作者：何向磊毛傲华孙萌萌邹继同王晓钢 School of Physics Harbin Institute of TechnologyHarbin 150001China Laboratory for Space Environment and Materials Science Harbin Institute of TechnologyHarbin 150001China

Magnetic reconnection processes in three-dimensional(3D)complex field configurations have been investigated in different magneto-plasma systems in space,laboratory,and astrophysical ***-dimensional(2D)features of magnetic reconnection have been well developed and applied successfully to systems with symmetrical property,such as toroidal fusion plasmas and laboratory experiments with an axial *** in asymmetric systems,the 3D features are inevitably different from those in the 2D *** reconnection structures in multiple celestial body systems,particularly star-planet-Moon systems,bring fresh insights to the understanding of the 3D geometry of ***,we take magnetic reconnection in an ancient solar-lunar terrestrial magneto-plasma system as an example by using its crucial parameters approximately estimated already and also some specific applications in pathways for energy and matter transports among Earth,ancient Moon,and the interplanetary magnetic field(IMF).Then,magnetic reconnection of the ancient lunar-terrestrial magnetospheres with the IMF is investigated numerically in this *** a 3D simulation for the Earth-Moon-IMF system,topological features of complex magnetic reconnection configurations and dynamical characteristics of magnetic reconnection processes are *** is found that a coupled lunar-terrestrial magnetosphere is formed,and under various IMF orientations,multiple X-points emerge at distinct locations,showing three typical magnetic reconnection structures in such a geometry,i.e.,the X-line,the triple current sheets,and the A-B null *** results can conduce to further understanding of reconnection physics in 3D for plasmas in complex magnetic configurations,and also a possible mechanism for energy and matters transport in evolutions of similar astrophysical systems.

关键词： magnetic reconnection multiple X-points complex magneto-plasma system

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急性双侧桥臂梗死的临床特征分析

中华神经科杂志 2024年第8期57卷 859-866页

作者：袁子云刘然相蕾岳伟天津市环湖医院神经内科天津300350 天津医科大学神经内外科及神经康复临床学院天津市环湖医院神经内科天津300350

目的研究急性双侧桥臂梗死患者的临床表现、影像学、发病机制及预后相关影响因素。方法连续收集2016年10月至2021年10月于天津市环湖医院住院治疗的急性双侧桥臂梗死患者,收集患者的人口学信息、临床症状及体征、影像学及预后等资料。... 详细信息

目的研究急性双侧桥臂梗死患者的临床表现、影像学、发病机制及预后相关影响因素。方法连续收集2016年10月至2021年10月于天津市环湖医院住院治疗的急性双侧桥臂梗死患者,收集患者的人口学信息、临床症状及体征、影像学及预后等资料。用二元Logistic回归分析年龄、性别、卒中危险因素、梗死部位、血管情况、入院时美国国立卫生研究院卒中量表(NIHSS)评分及卒中进展情况与双侧桥臂梗死患者90 d预后的相关性。结果共纳入112例急性双侧桥臂梗死患者。最常见的临床特点为共济失调(84.8%,95/112)和眩晕(75.0%,84/112);23例(20.5%,23/112)患者首发症状为耳鸣/听力下降,其中4例为突发性耳聋。伴脑桥梗死90例(80.4%),伴中脑梗死22例(19.6%),伴延髓梗死21例(18.8%),伴小脑梗死86例(76.8%),孤立性双侧桥臂梗死仅有8例(7.1%,8/112)。在进行血管影像学检查的患者中,89.0%(89/100)存在椎基底动脉系统中重度狭窄/闭塞,65.0%(65/100)的患者双侧椎动脉和(或)基底动脉中重度狭窄/闭塞。发病机制以大动脉粥样硬化型为主(79.5%,89/112)。进展性卒中(OR=7.765,95%CI 2.760~21.841,P<0.001)及入院时NIHSS评分较高(OR=1.196,95%CI 1.085~1.318,P<0.001)是双侧桥臂梗死患者预后不良的独立危险因素。结论急性双侧桥臂梗死患者首发症状多为眩晕,急性前庭及听力障碍是桥臂梗死的特征性表现。孤立性双侧桥臂梗死临床少见,影像学检查显示多数合并后循环其他部位梗死,脑桥及小脑是最易累及的部位。发病机制以大动脉粥样硬化型为主。进展性卒中及入院时NIHSS评分较高是患者预后不良的独立危险因素。

关键词：脑梗死桥臂磁共振成像预后