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Promotion of axon regeneration and inhibition of astrocyte activation by alpha A-crystallin on crushed optic nerve

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International Journal of Ophthalmology(English edition) 2016年第7期9卷 955-966页

作者： Wei-Yang Shao Xiao Liu xian-liang gu Xi Ying Nan Wu Hai-Wei Xu Yi Wang Southwest Hospital/Southwest Eye Hospital Third Military Medical University Chongqing 400038 China Key Lab of Visual Damage and Regeneration & Restoration of Chongqing Chongqing 400038 China

AIM：To explore the effects of αA-crystallin in astrocyte gliosis after optic nerve crush（ONC） and the mechanism of α-crystallin in neuroprotection and axon ***：ONC was established on the SpragueDawley rat model and αA-crystallin（10 -4 g/L,4 μL） was intravitreously injected into the rat ***-visual evoked potential（F-VEP） was examined 14 d after ONC,and the glial fibrillary acidic protein（GFAP） levels in the retina and crush site were analyzed 1,3,5,7 and 14 d after ONC by immunohistochemistry（IHC） and Western blot *** levels of beta Tubulin（TUJ1）,growth-associated membrane phosphoprotein-43（GAP-43）,chondroitin sulfate proteoglycans（CSPGs） and neurocan were also determined by IHC 14 d after ***：GFAP level in the retina and the optic nerve significantly increased 1d after ONC,and reached the peak level 7d *** of αA-crystallin significantly decreased GFAP level in both the retina and the crush site 3d after ONC,and induced astrocytes architecture remodeling at the crush *** of retinal ganglion cell（RGC） axons indicated αAcrystallin markedly promoted axon regeneration in ONC rats and enhanced the regenerated axons penetrated into the glial *** and neurocan expression also decreased 14 d after αA-crystallin *** amplitude（N1-P1） and latency（P1） of F-VEP were also ***：Our results suggest α-crystallin promotes the axon regeneration of RGCs and suppresses the activation of astrocytes.

关键词： αA-crystallin axonal regeneration astrocyte glial scar chondroitin sulfate proteoglycans optic nerve crush

Method for rapid warning and activity concentration estimates in online waterγ-spectrometry systems

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Nuclear Science and Techniques 2024年第3期35卷 1-12页

作者： Meng Wang Yi gu Mao-Lin Xiong liang-Quan Ge Qing-xian Zhang guo-Qiang Zeng Heng Lu Sheng-liang guo College of Nuclear Technology and Automation Engineering Chengdu University of TechnologyChengdu 610059China Applied Nuclear Technology in Geosciences Key Laboratory of Sichuan Province (Chengdu University of Technology)Chengdu 610059China Chengdu New Ray Technology Co.Ltd Chengdu 610052China

Onlineγ-spectrometry systems for inland waters,most of which extract samples in situ and in real time,are able to produce reliable activity concentration measurements for waterborne radionuclides only when they are distributed relatively uniformly and enter into a steady-state diffusion regime in the measurement *** protect residents’health and ensure the safety of the living environment,better timeliness is required for this measurement *** address this issue,this study established a mathematical model of the online waterγ-spectrometry system so that rapid warning and activity estimates can be obtained for water under non-steady-state(NSS)*** addition,the detection efficiency of the detector for radionuclides during the NSS diffusion process was determined by applying the computational fluid dynamics technique in conjunction with Monte Carlo *** this basis,a method was developed that allowed the online waterγ-spectrometry system to provide rapid warning and activity concentration estimates for radionuclides in *** analysis of the NSS-mode measurements of^(40)K radioactive solutions with different activity concentrations determined the optimum warning threshold and measurement time for producing accurate activity concentration estimates for *** experimental results show that the proposed NSS measurement method is able to give warning and yield accurate activity concentration estimates for radionuclides 55.42 and 69.42 min after the entry of a 10 Bq/L^(40)K radioactive solution into the measurement chamber,*** times are much shorter than the 90 min required by the conventional measurement ***,the NSS measurement method allows the measurement system to give rapid(within approximately 15 min)warning when the activity concentrations of some radionuclides reach their respective limits stipulated in the guidelines for Drinking-water Quality of the WHO,suggesting that this method con

关键词： Water radioactivity monitoring Dynamic detection efficiency Rapid warning Activity estimation

An adaptive 3D reconstruction method for asymmetric dual-angle multispectral stereo imaging system on UAV platform

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Science China(Information Sciences) 2024年第8期67卷 285-299页

作者： Chen WANG xian LI Yanfeng gu Zixu WANG School of Electronics and Information Engineering Harbin Institute of Technology Beijing Institute of Control and Electronic Technology

A multispectral imaging system often cannot capture 3D spatial information owing to hardware limitations, which diminishes the effectiveness across various domains. To address this problem, we have developed a multispectral stereo imaging system along with an adaptive 3D reconstruction algorithm. Unlike existing unmanned aerial vehicle stereo imaging systems, our multispectral stereo imaging system uses two multispectral cameras with asymmetric spectral bands positioned at different angles. This design enables the acquisition of a higher number of bands and lateral spatial information while maintaining a lightweight structure. This system introduces challenges such as large geometric distortions and intensity differences between multiple bands. To accurately recover 3D spatial information, we propose an adaptive 3D reconstruction method. This method employs a position and orientation system-assisted projection transformation and a normalized threshold adjustment strategy. Finally, mutual information is used to reconstruct the multispectral images densely, effectively addressing nonlinear differences and generating a comprehensive multispectral point cloud. Our stereo system was used for two real data collections in different regions, and the efficacy of the proposed 3D reconstruction method was validated by comparing it with existing methods and commercial software.

关键词： 3D reconstruction feature extraction multispectral images stereo imaging system unmanned aerial vehicle

MLDA:a multi-level k-degree anonymity scheme on directed social network graphs

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Frontiers of Computer Science 2024年第2期18卷 199-215页

作者： Yuanjing HAO Long LI liang CHANG Tianlong gu guangxi Key Laboratory of Trusted Software Guilin University of Electronic TechnologyGuilin 541004China Engineering Research Center of Trustworthy AI(Ministry of Education) Jinan UniversityGuangzhou 510632China

With the emergence of network-centric data,social network graph publishing is conducive to data analysts to mine the value of social networks,analyze the social behavior of individuals or groups,implement personalized recommendations,and so ***,published social network graphs are often subject to re-identification attacks from adversaries,which results in the leakage of users’***-anonymity technology is widely used in the field of graph publishing,which is quite effective to resist re-identification ***,the current researches still exist some issues to be solved:the protection of directed graphs is less concerned than that of undirected graphs;the protection of graph structure is often ignored while achieving the protection of nodes’identities;the same protection is performed for different users,which doesn’t meet the different privacy requirements of ***,to address the above issues,a multi-level-degree anonymity(MLDA)scheme on directed social network graphs is proposed in this ***,node sets with different importance are divided by the firefly algorithm and constrained connectedness upper approximation,and they are performed different-degree anonymity protection to meet the different privacy requirements of ***,a new graph anonymity method is proposed,which achieves the addition and removal of edges with the help of fake *** addition,to improve the utility of the anonymized graph,a new edge cost criterion is proposed,which is used to select the most appropriate edge to be ***,to protect the community structure of the original graph as much as possible,fake nodes contained in a same community are merged prior to fake nodes contained in different *** results on real datasets show that the newly proposed MLDA scheme is effective to balance the privacy and utility of the anonymized graph.

关键词： directed social network graph graph publishing k-degree anonymity community structure graph utility

Intelligent reflecting surfaces-assisted millimeter wave communication:Channel estimation based on deep learning

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The Journal of China Universities of Posts and Telecommunications 2024年第1期31卷 49-56页

作者： Kang Xiaofei Wang Tian liang xian College of Communication and Information Engineering Xi'an University of Science and TechnologyXi'an 710600China

In response to the challenge posed by the complexity of the system and the difficulty in obtaining accurate channel state information(CSI)for millimeter wave communication assisted by intelligent reflecting surfaces(IRS),we propose a deep learning-based channel estimation *** proposed scheme employs a hybrid active/passive IRS architecture,wherein the least square(LS)algorithm is initially utilized to acquire the channel estimate from the active ***,this estimation is interpolated to obtain a preliminary channel estimation and ultimately refined into an accurate estimate of the channel using the channel super-resolution convolutional neural network(Chan-SRCNN)deep learning *** simulation results demonstrate that the proposed scheme surpasses LS,orthogonal matching pursuit(OMP),synchronous OMP(SOMP),and deep neural network(DNN)channel estimation algorithms in terms of normalized mean squared error(NMSE)performance,thereby validating the feasibility of the proposed approach.

关键词： intelligent reflecting surface millimeter wave channel estimation deep learning

Multi-sensor multispectral reconstruction framework based on projection and reconstruction

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Science China(Information Sciences) 2024年第3期67卷 246-262页

作者： Tianshuai LI Tianzhu LIU xian LI Yanfeng gu Yukun WANG Yushi CHEN School of Electronics and Information Engineering Harbin Institute of Technology Heilongjiang Province Key Laboratory of Space-Air-Ground Integrated Intelligent Remote Sensing

The scarcity and low spatial resolution of hyperspectral images(HSIs) have become a major problem limiting the application of the images. In recent years, spectral reconstruction(SR) has been applied to convert multispectral images(MSIs) with abundant quantities and high spatial resolution into HSIs. With the launch of several new multispectral(MS) satellites with a short repeat period, the simultaneous acquisition of images from multiple MS sensors in the same area is gradually becoming feasible. Unfortunately, existing SR methods only consider the reconstruction of the MSIs of a single sensor without considering using MSIs from different MS sensors to obtain a better construction effect through their complementary bands. However,multi-sensor SR is characterized by two problems: inconsistency in the amplitude information of real multisensor imaging and difficulty in the extraction of the complex correlations of bands from different *** solve these problems, this paper proposes a multi-sensor SR framework based on a two-step approach in which the problems of amplitude inconsistency and band information extraction are solved using an ideal projection network and an ideal multi-sensor SR network, respectively. The effectiveness of the proposed method is verified by experiments on three datasets.

关键词： spectral reconstruction spectral superresolution hyperspectral image multispectral image neural networks multi-sensor

Hybrid vibration isolation optimization of a flexible manipulator based on neural network agent model

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Chinese Journal of Aeronautics 2024年第5期37卷 482-505页

作者： Yongxin ZHANG liang LI Dingguo ZHANG Wei-Hsin LIAO xian guO School of Science Nanjing University of Science and TechnologyNanjing 210094China Department of Mechanical and Automation Engineering The Chinese University of Hong KongHong KongChina

Segmented Active Constrained Layer Damping(SACLD)is an intelligent vibration-damping structure,which could be applied to the sectors of aviation,aerospace,and transportation engineering to reduce the vibration of flexible ***,machine learning technology is widely used in the engineering field because of its efficient multi-objective *** dynamic simulation of a rotational segmental flexible manipulator system is presented,in which enhanced active constrained layer damping is carried out,and the neural network model of Genetic Algorithm-Back Propagation(GA-BP)algorithm is *** suppression and structural optimization of the SACLD manipulator model are studied based on vibration mode and damping *** modal responses of the SACLD manipulator model at rest and rotation are *** addition,the four model indices are optimized using the GA-BP neural network:axial incision size,axial incision position,circumferential incision size,and circumferential incision ***,the best model for vibration suppression is obtained.

关键词： Machine learning Vibration suppression Flexible manipulator Segmented active constrained layer damping Structural optimization

An Analysis of the Fragmentation of Observing Time At the Muztagh-Ata Site

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Research in Astronomy and Astrophysics 2024年第3期24卷 29-33页

作者： Wen-Bo gu Jing Xu guo-Jie Feng Xuan Zhang Le-Tian Wang Xin-liang Wang Ali Esamdin Li-xian Shen Xinjiang Astronomical Observatory Chinese Academy of SciencesUrumqi 83001lChina School of Astronomy and Space Science University of Chinese Academy of SciencesBeijing 100049China

Cloud cover plays a pivotal role in assessing observational conditions for astronomical *** for the fraction of observing time,its fragmentation also wields a significant influence on the quality of nighttime sky *** this article,we introduce the functionΓ∈[0,1],designed to comprehensively capture both the fraction of available observing time and its *** in situ measurement data gathered at the Muztagh-Ata site between 2017 and 2021,we showcase the effectiveness of our *** statistical result illustrates that the Muztagh-Ata site affords approximately 122 nights that were absolutely clear and 205 very good nights annually,corresponding toΓ≥0.9 andΓ≥0.36 respectively.

关键词： site testing-atmospheric effects-methods statistical

Manipulation of magnetocaloric and elastocaloric effects in Ni-Mn-In alloys by lattice volume and magnetic variation:Effect of Co and Fe co-doping

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Journal of Materials Science & Technology 2024年第5期172卷 156-165页

作者： Xinzeng liang Chi Zhang Jing Bai Jianglong gu Yudong Zhang Claude Esling xiang Zhao liang Zuo School of Materials Science and Engineering Shenyang University of TechnologyShenyang 110870China Key Laboratory for Anisotropy and Texture of Materials Northeastern UniversityShenyang 110819China School of Resources and Materials Northeastern University at QinhuangdaoQinhuangdao 066004China State Key Laboratory of Metastable Materials Science and Technology Yanshan UniversityQinhuangdao 066004China Laboratoire d’Étude des Microstructures et de Mécanique des Matériaux LEM3 CNRSUMR 7239University of Lorraine57045 MetzFrance

The effects of Co and Fe co-doping Ni-Mn-In alloy on the phase stability,lattice parameters,mag-netic properties,and electronic structures are systematically investigated by using the first-principles *** indicate that Fe atoms replace the excess Mn2 atoms by direct and indirect coex-istence(Fe→Mn 2 and Fe→In→Mn2);Co substitutes the Ni atoms by direct substitution(Co→Ni)for the Ni-Mn-In *** austenites all exhibit the ferromagnetic(FM)state for the studied *** NM martensites are in the ferrimagnetic(FIM-1)state for the Ni_(2)Mn_(1.5)In_(0.5),Ni_(2)Mn_(1.25)In_(0.5)Fe 0.25,Ni_(1.75)Mn_(1.5)In_(0.5)Co_(0.25),and Ni_(1.75)Mn_(1.25)In_(0.5)Co_(0.25)Fe 0.25 alloys,while the other compositions are in the FM *** phase stability of austenite and martensite decreases with increasing Co and Fe co-doping.A magnetic-structural coupling transition occurs at x<0.25 and y<*** Ni_(1.91)Mn_(1.5)In_(0.5)Co_(0.08)and Ni_(1.91)Mn_(1.42)In_(0.5)Co_(0.08)Fe_(0.08)alloys exhibit an A→6M→NM transformation,accompanied by a magnetic *** Co and Fe are co-doped,the hybridization strength between Co and Fe is greater than that between Co/Fe and *** enhancement of magnetocaloric and elastocaloric effects is favored by larger magnetization difference(△M)and lattice volume change(△V/V_(0)).Based on the calculated phase stability,magneto-structure coupling,△V/V 0 and c/a ratio,one can predict that the Ni_(2)-x Mn_(1.5)-y In_(0.5)Co x Fe y alloy with Co content 0≤x≤0.25 and Fe content 0≤y≤0.05 is predicted to have good magneto-controlled functional behavior.

关键词： Ni-Mn-In-Co-Fe Phase stability Magnetocaloric effect Elastocaloric effect