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Tungsten 2022年第2期4卷 121-129页

作者： Meng Zhao xi-yu zhu Yan-Zhen Li Jiang-Nan Chang Ming-Xue Li Li-Hua Ma xiao-yuan Guo Henan Key Laboratory of Polyoxometalate Chemistry Institute of Molecular and Crystal EngineeringSchool of Chemistry and Chemical EngineeringHenan UniversityKaifeng475004China Agricultural Products’Quality and Safety Testing Center of Kaifeng Kaifeng Agriculture and Rural BureauHenan475004China

In this paper,a new organic–inorganic hybrid compound[Co(L)_(2)]2[W_(6)O_(19)](1)(HL=2-acetylpyridine thiosemicarbazone)was prepared and characterized.The compound 1 exhibits remarkable antibacterial activity by determination of minimum inhibitory concentration(MIC)against Staphylococcus aureus(S.aureus,0.06μg·mL^(−1))and Escherichia coli(E.coli,0.24μg·mL^(−1)),respectively.Furthermore,the potential mechanism of compound 1 was studied in detail.The potential causes of bacteria death were cell wall/membrane disruption,inhibition of intracellular respiratory chain dehydrogenases(RCD)activity,destruction of reactive oxygen species(ROS)and depletion of glutathione(GSH).

关键词： Isopolytungstate Thiosemicarbazone Bioactivity Mechanism of action

Robust superconductivity and transport properties in (Li_(1-x)Fe_x)OHFeSe single crystals

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Science China(Physics,Mechanics & Astronomy) 2016年第5期59卷 11-15页

作者： Hai Lin Jie xing xi yu zhu Huan Yang Hai-Hu Wen Center for Superconducting Physics and Materials National Laboratory of Solid State Microstructures and Department of PhysicsNational Collaborative Innovation Center of Advanced Microstructures Nanjing University

The recently discovered(Li_(1-x) Fe_x)OHFe Se superconductor with T c about 40 K provides a good platform for investigating the magnetization and electrical transport properties of Fe Se-based superconductors. By using a hydrothermal ion-exchange method,we have successfully grown crystals of(Li_(1-x) Fe_x)OHFe Se. X-ray diffraction on the sample shows the single crystalline Pb O-type structure with the c-axis preferential orientation. Magnetic susceptibility and resistive measurements show an onset superconducting transition at around T c=38.3 K. Using the magnetization hysteresis loops and Bean critical state model, a large critical current J s is observed in low temperature region. The critical current density is suppressed exponentially with increasing magnetic field.Temperature dependencies of resistivity under various currents and fields are measured, revealing a robust superconducting current density and bulk superconductivity.

关键词：电输运性质单晶体超导性临界电流密度超导电流密度电阻测量 X射线衍射临界态模型

Genesis of ultra-deep dolostone and controlling factors of largescale reservoir:A case study of the Sinian Dengying Formation and the Cambrian Longwangmiao Formation in the Sichuan Basin

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Science China Earth Sciences 2024年第7期67卷 2352-2382页

作者： xi LI Guangyou zhu Zhiyao ZHANG PetroChina Research Institute of Petroleum Exploration and Development Beijing 100083China School of Geosciences Yangtze UniversiyWuhan 430100China School of Earth Resoures China University of GeosciencesWuhan 430074China

This paper investigates the origin of ultra-deep dolostone and the factors influencing large-scale dolostone reservoirs,focusing on the Sinian Dengying Formation and the Cambrian Longwangmiao Formation in the Sichuan Basin.The study involves petrology,microscale X-ray diffraction,trace element analysis,and C-O-Sr-Mg isotope experiments to provide a detailed analysis.The research findings indicate that the Dengying and Longwangmiao formations comprise six types of matrix dolostone and four types of cement.The Dengying Formation,which developed under a sedimentary background of a restricted platform,contains special microbial and microcrystalline dolostones.The dolomite grains are small(30μm),high order degree(Min=0.7),small unit cell parameters,high Na content(Max=432 ppm),and low Fe and Mn content.The δ^(2

关键词： Ultra-deep layers Dolostone Supercontinent evolution Microscale geochemistry Dengying Formation Longwangmiao Formation Sichuan Basin

Bioengineered skin organoids:from development to applications

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Military Medical Research 2024年第3期11卷 449-466页

作者： Zi-Xuan Hong Shun-Tian zhu Hao Li Jing-Zhi Luo yu Yang Yang An xi Wang Kai Wang Department of Physiology and Pathophysiology School of Basic Medical SciencesState Key Laboratory of Vascular Homeostasis and RemodelingPeking UniversityBeijing 100191China Department of Hepatopancreatobiliary Surgery the Third Affiliated Hospital of Soochow UniversityChangzhou 213000JiangsuChina Department of Plastic Surgery Peking University Third HospitalBeijing 100191China Clinical Stem Cell Research Center Peking University Third HospitalBeijing 100191China State Key Laboratory of Cardiovascular Disease Fuwai HospitalBeijing 100037China Beijing Key Laboratory of Metabolic Disorder Related Cardiovascular Disease Capital Medical UniversityBeijing 100050China

Signifcant advancements have been made in recent years in the development of highly sophisticated skin organoids.Serving as three-dimensional(3D)models that mimic human skin,these organoids have evolved into complex structures and are increasingly recognized as efective alternatives to traditional culture models and human skin due to their ability to overcome the limitations of two-dimensional(2D)systems and ethical concerns.The inherent plasticity of skin organoids allows for their construction into physiological and pathological models,enabling the study of skin development and dynamic changes.This review provides an overview of the pivotal work in the progression from 3D layered epidermis to cyst-like skin organoids with appendages.Furthermore,it highlights the latest advancements in organoid construction facilitated by state-of-the-art engineering techniques,such as 3D printing and microfuidic devices.The review also summarizes and discusses the diverse applications of skin organoids in developmental biology,disease modelling,regenerative medicine,and personalized medicine,while considering their prospects and limitations.

关键词： Skin organoid Organoid generation Skin appendage Tissue engineering Disease modelling Regenerative medicine

TRPC6 Knockout Alleviates Renal Fibrosis through PI3K/AKT/GSK3B Pathway

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Current Medical Science 2024年第3期44卷 589-602页

作者： An-bang SUN Fang-hua LI Lin zhu xi-xi ZENG Min zhu Qing-hua LEI Yan-hong LIAO Department of Anatomy School of Basic MedicineTongji Medical CollegeHuazhong University of Science and TechnologyWuhan430030China Department of Transfusion Medicine Wuhan Hospital of Traditional Chinese and Western MedicineTongji Medical CollegeHuazhong University of Science and TechnologyWuhan430030China Department of Nephrology The First Affiliated Hospital of Zhengzhou UniversityZhengzhou450052China Department of Thoracic Surgery Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan430030China National Basic Medical Teaching Demonstration Center Tongji Medical CollegeHuazhong University of Science and TechnologyWuhan430030China Key Laboratory of Neurological Diseases of Ministry of Education Tongji Medical CollegeHuazhong University of Science and TechnologyWuhan430030China

Objective Renal fibrosis is the ultimate pathway of various forms of acute and chronic kidney damage.Notably,the knockout of transient receptor potential channel 6(TRPC6)has shown promise in alleviating renal fibrosis.However,the regulatory impact of TRPC6 on renal fibrosis remains unclear.Methods In vivo,TRPC6 knockout(TRPC6−/−)mice and age-matched 129 SvEv(WT)mice underwent unilateral renal ischemia-reperfusion(uIR)injury surgery on the left renal pedicle or sham operation.Kidneys and serum were collected on days 7,14,21,and 28 after euthanasia.In vitro,primary tubular epithelial cells(PTECs)were isolated from TRPC6−/−and WT mice,followed by treatment with transforming growth factorβ1(TGFβ1)for 72 h.The anti-fibrotic effect of TRPC6−/−and the underlying mechanisms were assessed through hematoxylin-eosin staining,Masson staining,immunostaining,qRT-PCR,and Western blotting.Results Increased TRPC6 expression was observed in uIR mice and PTECs treated with TGFβ1.TRPC6−/−alleviated renal fibrosis by reducing the expression of fibrotic markers(Col-1,α-SMA,and vimentin),as well as decreasing the apoptosis and inflammation of PTECs during fibrotic progression both in vivo and in vitro.Additionally,we found that the phosphatidylinositol 3-kinase(PI3K)/protein kinase B(AKT)/glycogen synthase kinase 3 beta(GSK3β)signaling pathway,a pivotal player in renal fibrosis,was down-regulated following TRPC6 deletion.Conclusion These results suggest that the ablation of TRPC6 may mitigate renal fibrosis by inhibiting the apoptosis and inflammation of PTECs through down-regulation of the PI3K/AKT/GSK3βpathway.Targeting TRPC6 could be a novel therapeutic strategy for preventing chronic kidney disease.

关键词： transient receptor potential channel 6 ischemia-reperfusion injury renal fibrosis renal tubular epithelial cells

Topological Stability and Entropy for Certain Set-valued Maps

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Acta Mathematica Sinica,English Series 2024年第4期40卷 962-984页

作者： yu ZHANG yu Jun zhu School of Mathematical Sciences Xiamen UniversityXiamen 361005P.R.China

In this paper,the dynamics(including shadowing property,expansiveness,topological stability and entropy)of several types of upper semi-continuous set-valued maps are mainly considered from differentiable dynamical systems points of view.It is shown that(1)if f is a hyperbolic endomorphism then for eachε>0 there exists a C^(1)-neighborhood U of f such that the induced set-valued map F_(f,U)has theε-shadowing property,and moreover,if f is an expanding endomorphism then there exists a C^(1)-neighborhood U of f such that the induced set-valued map F_(f,U)has the Lipschitz shadowing property;(2)when a set-valued map F is generated by finite expanding endomorphisms,it has the shadowing property,and moreover,if the collection of the generators has no coincidence point then F is expansive and hence is topologically stable;(3)if f is an expanding endomorphism then for eachε>0 there exists a C^(1)-neighborhood U of f such that h(F_(f,U,ε))=h(f);(4)when F is generated by finite expanding endomorphisms with no coincidence point,the entropy formula of F is given.Furthermore,the dynamics of the set-valued maps based on discontinuous maps on the interval are also considered.

关键词： Set-valued map orbit space hyperbolic endomorphism perturbation shadowing expansiveness topological stability entropy

Chain Extender-induced Hydrogen Bonding Organization Determines the Morphology and Properties of Thermoplastic Polycarbonate Polyurethane

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Chinese Journal of Polymer Science 2024年第1期42卷 87-96,I0009页

作者： Yi-Lang Qin Ping zhu Chen-xi Ouyang xia Dong Fuwai Hospital Chinese Academyof Medical Sciences&Peking Union Medical College/National Center for Cardiovascular DiseasesBejing 100037China CASKey Laboratoryof Engineering Plastics CAS Research/Education Centerfor Excellence in Molecular SciencesInstitute ofChemistryChinese Academy of SciencesBeijing 100190China University of Chinese Academy of Sciences Beijing 100049China

Thermoplastic polycarbonate polyurethanes(PCUs) are multiblock copolymers that have been applied for medical devices for long time. Aliphatic diols are common chain extenders(CE) involved in the composition of the hard segments of PCU. However, limited knowledge was discovered about how the chemical structure of CE affects the hydrogen bonding organization within PCUs and their mechanical properties.To investigate this problem, a group of PCUs were synthesized respectively by extending the polymer chain with 1,4-butanediol(BDO),aminoethanol(MEA), ethanediol(EO) as three kinds of chain extenders. Tiny differences in the CE chemical structure results in remarkable variations in phase separation, condensed morphologies, thermal and mechanical properties, which are characterized by Fourier transform infrared spectrometer, atomic force microscopy, small-angle X-ray scattering, differential scanning calorimetry, and tensile tests. The microstructural evolution during unilateral deformation and the different mechanism induced by the different CEs was probed and unveil by in situ wide-and small-angle X-ray diffraction. Symmetry of CE can improve the organization of the hydrogen bonding. The coherence strength of the urethane/urea group also plays a key role by comparing the two PCUs with ethanediol and aminoethanol.

关键词： Thermoplastic polycarbonate polyurethane Chain extender Hydrogen bonding Mechanical properties

Chemical Scissors Tailored Nano‑Tellurium with High‑Entropy Morphology for Efficient Foam‑Hydrogel‑Based Solar Photothermal Evaporators

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Nano-Micro Letters 2024年第3期16卷 149-168页

作者： Chenyang xing Zihao Li Ziao Wang Shaohui Zhang Zhongjian xie xi zhu Zhengchun Peng State Key Laboratory of Radio FrequencyHeterogeneous Integration Shenzhen UniversityShenzhen 518060People’s Republic of China Center for Stretchable Electronics and NanoSensors College of Physics and Optoelectronic EngineeringShenzhen UniversityShenzhen 518060People’s Republic of China School of Science and Engineering The Chinese University of Hong KongShenzhenShenzhen 518172People’s Republic of China Institute of Pediatrics Shenzhen Children’s HospitalShenzhen 518038GuangdongPeople’s Republic of China International Collaborative Laboratory of 2D Materials for Optoelectronics Science and Technology of Ministry of Education Institute of Microscale OptoelectronicsShenzhen UniversityShenzhen 518060People’s Republic of China

The development of tellurium(Te)-based semiconductor nanomaterials for efficient light-to-heat conversion may offer an effective means of harvesting sunlight to address global energy concerns.However,the nanosized Te(nano-Te)materials reported to date suffer from a series of drawbacks,including limited light absorption and a lack of surface structures.Herein,we report the preparation of nano-Te by electrochemical exfoliation using an electrolyzable room-temperature ionic liquid.Anions,cations,and their corresponding electrolytic products acting as chemical scissors can precisely intercalate and functionalize bulk Te.The resulting nano-Te has high morphological entropy,rich surface functional groups,and broad light absorption.We also constructed foam hydrogels based on poly(vinyl alcohol)/nano-Te,which achieved an evaporation rate and energy efficiency of 4.11 kg m^(−2)h^(−1)and 128%,respectively,under 1 sun irradiation.Furthermore,the evaporation rate was maintained in the range 2.5-3.0 kg m^(−2)h^(−1)outdoors under 0.5-1.0 sun,providing highly efficient evaporation under low light conditions.

关键词： Tellurium High entropy Electrochemical modification Solar absorption Evaporation rate

Capture Efficiency Analysis in the Circular Restricted Three-body Problem

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Research in Astronomy and Astrophysics 2024年第5期24卷 198-210页

作者： yu-Xuan Miao xi-yun Hou Department of Astronomy and Space Science Nanjing UniversityNanjing 210023China Institute of Space Environment and Astrodynamics Nanjing UniversityNanjing 210023China Key Laboratory of Modern Astronomy and Astrophysics Ministry of EducationNanjing 210023China

Temporary capture efficiency is studied in the framework of the circular restricted three-body problem in two steps.First, a non-uniform distribution of test particles around the secondary's orbit is obtained by fully accounting the secondary's gravitational influence. Second, the capture efficiency is computed based on the non-uniform distribution. Several factors influencing the result are discussed. By studying the capture efficiency in the circular restricted three-body problem of different mass ratios, a power-law relation between the capture efficiency(p) and the mass ratio(μ) is established, which is given by p ≈ 0.27 × μ^(0.53), within the range of 3.0035 ×10^(-6)≤ μ ≤ 3.0034 × 10^(-5). Taking the Sun–Earth system as an example, the influence from the orbit eccentricity of the secondary on the non-uniform distribution and the capture efficiency is studied. Our studies find that the secondary's orbit eccentricity has a negative influence on the capture efficiency.

关键词： methods numerical-celestial mechanics-planets and satellites dynamical evolution and stability

Learning background restoration and local sparse dictionary for infrared small target detection

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Optoelectronics Letters 2024年第7期20卷 437-448页

作者： HE yue ZHANG Rui xi Chunmei zhu Hu School of Communications and Information Engineering Nanjing University of Posts and Telecommunications

This paper proposes a method for learning background restoration for infrared small target detection, employing a local sparse dictionary alongside an equalized structural texture representation. The method is specifically designed for the detection of small infrared targets, accommodating various levels of brightness, spatial size, and intensity. Our proposed model intelligently combines global low-rankness and local sparsity to estimate the rank of the background tensor, leveraging spatial and structural information to overcome the limitations posed by insufficient detailed texture knowledge. Subsequently, a structural texture representation, combining local gradient maps and local intensity maps, is applied to emphasize small objects. By comparing our method with nine advanced and representative approaches and quantifying the comparison using various metrics, the experimental results indicate that our proposed method has achieved favorable outcomes in both quantitative assessments and visual results.

关键词： A