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Nuclear Science and Techniques 2022年第10期33卷 53-67页

作者： Jing Chen Ze-Shi Liu Hao Jiang xi-ren miao Yong Xu College of Electrical Engineering and Automation Fuzhou UniversityFuzhou 350108China The Department of Automation Shanghai Jiao Tong UniversityShanghai 200240China Fujian Fuqing Nuclear Power Co. Ltd.Fujian 350318China

Anomaly detection for the control rod drive mechanism(CRDM) is key to enhancing the security of nuclear power plant equipment. In CRDM real-time condition-based maintenance, most existing methods cannot deal with long sequences and periodic abnormal events and have poor feature extraction from these data. In this paper,a learning-based anomaly detection method employing a long short-term memory-based autoencoder(LSTM-AE)network and an extreme gradient boosting(XGBoost)algorithm is proposed for the CRDM. The nonlinear and sequential features of the CRDM coil currents can be automatically and efficiently extracted by the LSTM neural units and AE network. The normal behavior LSTM-AE model was established to reconstruct the errors when feeding abnormal coil current signals. The XGBoost algorithm was leveraged to monitor the residuals and identify outliers for the coil currents. The results demonstrate that the proposed anomaly detection method can effectively detect different timing sequence anomalies and provide a more accurate forecasting performance for CRDM coil current signals.

关键词： Anomaly detection CRDM LSTM-AE Residuals XGBoost

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本质与价值:数字时代广告本体的再认识

武汉大学学报（哲学社会科学版） 2025年第1期78卷 125-132页

作者：姚曦任文姣武汉大学新闻与传播学院湖北武汉430072 武汉大学媒体发展研究中心

用传播的方式促进从生产到消费转换的行为皆为存在意义上的广告,广告的本体是本质与价值的统一。本体的坚守要建立开放的认识观,在不变的广告本质中解释变化着的广告形态,而非用未触及本体的不确定认识窄化新的广告事实。彰显广告价值... 详细信息

用传播的方式促进从生产到消费转换的行为皆为存在意义上的广告,广告的本体是本质与价值的统一。本体的坚守要建立开放的认识观,在不变的广告本质中解释变化着的广告形态,而非用未触及本体的不确定认识窄化新的广告事实。彰显广告价值需深耕数字广告实践,用创意提升广告的社会吸引力,建构多主体参与的沟通网络。彰显广告价值还需要在理论层面,以本体观为支点,立足于本土广告实践,重新组织数字广告研究范畴,使用大数据技术与混合研究法探究新问题,为广告学知识体系的建构提供框架与方向。

关键词：广告广告本质广告价值广告本体

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Species identification of poisonous medicinal plant using DNA barcoding

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Chinese Journal of Natural Medicines 2019年第8期17卷 585-590页

作者： LIU miao LI xi-Wen LIAO Bao-Sheng LUO Lu ren Yue-Ying College of Chinese Medicine Materials Jilin Agriculture University Changchun 130118 China Institute of Chinese Materia Medica Academy of Chinese Medical Sciences Beijing 100700 China

The aim is to select a universal DNA barcode for identifying all poisonous medicinal plants in Chinese pharmacopoeia and their poisonous related species or adulterants. We chose 4 commonly used regions as candidate DNA barcodes(ITS2, psb A-trn H,matK and rbc L) and compared their identification efficiency in 106 species from 27 families and 65 genera totally. Data analysis was performed including the information of sequence alignment, inter/intra-specific genetic distance and data distribution, identification efficiency and the situation of Neighbor-Joining(NJ) phylogenetic trees. We found ITS2 sequence region had high variation, stable genetic distance and identification efficiency relatively. The topological structure of NJ phylogenetic tree showed monophyletic. Our findings show that ITS2 can be applied as a universal barcode for identifying poisonous medicinal plants in Chinese pharmacopoeia and their poisonous related species or adulterants.

关键词： Sequence Poisonous herbal medicine Genetic distance DNA barcoding ITS2 Blast

Characterization of the CpsQ Regulon Reveals Its Role in the Transcription of Type Ⅵ Secretion System 2 Genes in Vibrio parahaemolyticus

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Biomedical and Environmental Sciences 2024年第4期37卷 436-439页

作者： LUO xi LI Xue ZHANG miao miao HUANG Qing Lian ZHANG Yi Quan JI Shen Jie LU ren Fei Department of Clinical Laboratory Affiliated Nantong Hospital 3 of Nantong UniversityNantong Third People’s HospitalNantong 226006JiangsuChina Department of Clinical Laboratory Qidong People’s HospitalQidong 226200JiangsuChina

Vibrio parahaemolyticus,a gram-negative halophilic bacterium that naturally inhabits coastal waters,causes gastroenteritis,skin infections,and septicemia in human beings[1].This bacterium produces multiple virulence factors,including thermostable direct hemolysin(TDH),TDH-related hemolysin(TRH),type Ⅲ secretion system 1(T3SS1),T3SS2,type Ⅵ secretion system 1(T6SS1),and T6SS2[1].Furthermore,Ⅴ.parahaemolyticus forms biofilms on the surface,which help it in adapting to unfavorable conditions[2].Mature biofilm formation requires special structures,including lateral and polar flagella,exopolysaccharide(EPS),and type Ⅳ pili[2].

关键词： coastal system T3SS

The excluded-volume effect in microscopic pedestrian simulations

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Chinese Physics B 2012年第1期21卷 539-548页

作者： Guo ren-Yong Guo xi College of Computer Science Inner Mongolia UniversityHohhot 010021China School of Public Administration Inner Mongolia UniversityHohhot 010021China

We propose a pedestrian position update rule, which is added to a microscopic pedestrian model to avoid pedestrian overlap. In the rule, the step size of a pedestrian moving in a selected direction at each update is in inverse proportion to the repulsive actions imposed by other pedestrians moving in a direction with an exponential rate. The positions of the pedestrians are then updated in each small time interval. In this way, a barrier between the pedestrians can be generated, and after updating their positions the pedestrians do not overlap with each other. The modified model is compared to the original model through a simulation of the evacuation process of pedestrians in a closed area. The simulation results indicate that the modified model is superior to the original model in several aspects.

关键词： pedestrian model excluded-volume effect discrete dynamic system

Distributed Subgradient Algorithm for Multi-Agent Optimization With Dynamic Stepsize

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IEEE/CAA Journal of Automatica Sinica 2021年第8期8卷 1451-1464页

作者： xiaoxing ren Dewei Li Yugeng xi Haibin Shao Department of Automation Shanghai Jiao Tong UniversityShanghai 200240China

In this paper,we consider distributed convex optimization problems on multi-agent *** develop and analyze the distributed gradient method which allows each agent to compute its dynamic stepsize by utilizing the time-varying estimate of the local function value at the global optimal *** approach can be applied to both synchronous and asynchronous communication ***,we propose the distributed subgradient with uncoordinated dynamic stepsizes(DS-UD)algorithm for synchronous protocol and the AsynDGD algorithm for asynchronous *** analysis shows that the proposed algorithms guarantee that all agents reach a consensus on the solution to the multi-agent optimization ***,the proposed approach with dynamic stepsizes eliminates the requirement of diminishing stepsize in existing *** examples of distributed estimation in sensor networks are provided to illustrate the effectiveness of the proposed approach.

关键词： Distributed optimization dynamic stepsize gradient method multi-agent networks

To increase more than 10% in efficiency of perovskite solar cells by using nanoholes SnO_(2)

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Rare Metals 2021年第10期40卷 2778-2784页

作者： Shu-ren Sun xi-xi xie Guo-Gang Qin Li-xin xiao State Key Laboratory for Mesoscopic Physics and Department of Physics Peking UniversityBeijing 100871China Collaborative Innovation Center of Extreme Optics Shanxi UniversityTaiyuan 030006China

The perovskite solar cells have been intensively investigated these years due to their premium electrical and optical properties as well as huge potential for *** order to further increase the power conversion efficiency(PCE) of the thin film perovskite solar cells, light management should be taken into consideration. Herein, we apply a lithography method to transfer randomly distributed polystyrene(PS) nanospheres into the electron transporting SnO_(2) layer, by means of which, a nanoholes structure is formed. Finally, we get a nanostructured perovskite layer under low temperature(less than 150 ℃).The depth of SnO_(2) nanoholes is around 60 nm when the device is fabricated with 300-nm PS, and 150 nm in depth when 500-nm PS is used. The device gains PCE of 17.97%,which is 12.3% higher than that with planar electrontransporting SnO_(2) layer and 300-nm CH_(3)NH_(3)PbI_(3) *** findings provide an applicable method to improve the light absorption, which can not only make the absorbing layer of lead-based perovskite solar cells thinner to help decrease the content of lead, but also increase the PCE of non-lead perovskite devices.

关键词： Light trap Perovskite Solar cell Nanohole Nanosphere lithography

Enhancement of the second harmonic generation from monolayer WS_(2) coupled with a silica microsphere

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Chinese Physics B 2022年第10期31卷 417-422页

作者： xiao-Zhuo Qi xi-Feng ren CAS Key Laboratory of Quantum Information University of Science and Technology of ChinaHefei 230026China CAS Synergetic Innovation Center of Quantum Information and Quantum Physics University of Science and Technology of ChinaHefei 230026China

Monolayer transition metal dichalcogenides(TMDs) are widely used for integrated optical and photoelectric *** to their broken inversion symmetry, monolayer TMDs have a large second-order optical nonlinearity. However, the optical second-order nonlinear conversion efficiency of monolayer TMDs is still limited by the interaction length. In this work, we theoretically study the second harmonic generation(SHG) from monolayer tungsten sulfide(WS2) enhanced by a silica microsphere cavity. By tuning the position, size, and crystal orientation of the material, second-order nonlinear coupling can occur between the fundamental pump mode and different second harmonic cavity modes, and we obtain an optimal SHG conversion efficiency with orders of magnitude enhancement. Our work demonstrates that the microsphere cavity can significantly enhance SHG from monolayer 2D materials under flexible conditions.

关键词： integrated optics frequency conversion

Optogenetic tools controlled by ultraviolet-B light

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aBIOTECH 2021年第2期2卷 170-175页

作者： xinhao Ouyang Hui ren xi Huang State Key Laboratory of Cellular Stress Biology School of Life SciencesXiamen UniversityXiamen 361102China

Decades of genetic,molecular and biochemical studies in plants have provided foundational knowledge about light sensory proteins and led to their application in synthetic *** tools take advantage of the light switchable activity of plant photoreceptors to control intracellular signaling *** recent discovery of the UV-B photoreceptor UV RESISTANCE LOCUS 8 in the model plant Arabidopsis thaliana opens up new avenues for light-controllable *** this review,we discuss current developments in optogenetic control by UV-B light and its signaling components,as well as rational considerations in the design and applications of UV-B-based optogenetic tools.

关键词： Optogenetics UV-B light UVR8 COP1

Antagonizing adipose tissue-derived exosome miR-103-hepatocyte phosphatase and tensin homolog pathway alleviates autophagy in non-alcoholic steatohepatitis:A trans-cellular crosstalk

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World Journal of Gastroenterology 2023年第29期29卷 4528-4541页

作者： miao-miao Lu Yue ren Yu-Wei Zhou Ling-Ling Xu Meng-Meng Zhang Lin-Ping Ding Wei-xin Cheng xi Jin Endoscopy Center Children’s Hospital of Zhejiang University School of MedicineHangzhou 310003Zhejiang ProvinceChina Department of Medicine Zhejiang University School of MedicineHangzhou 310003Zhejiang ProvinceChina Department of Gastroenterology The Second People’s Hospital of Yuhang DistrictHangzhou 310003Zhejiang ProvinceChina Department of Gastroenterology Hangzhou Shangcheng District People’s HospitalHangzhou 310003Zhejiang ProvinceChina Department of Gastroenterology The First Affiliated Hospital of Zhejiang University School of MedicineHangzhou 310003Zhejiang ProvinceChina

BACKGROUND Obesity plays a vital role in the occurrence and development of non-alcoholic steatohepatitis(NASH).However,the underlining mechanism is still unclear,where adipose tissue(AT)derived exosomes may actively ***(miRNAs)are commonly secreted from exosomes for cell *** the regulation of miR-103 on insulin sensitivity has been reported,the specific role of AT-derived exosomes miR-103 in NASH is still vague and further investigation may provide novel therapeutic *** To determine the specific role of AT-derived exosomes miR-103 in developing NASH through various *** The expression levels of miR-103 in the AT-derived exosomes and livers were detected and compared between NASH mice and *** effect of miR-103 on NASH progression was also explored by antagonizing miR-103,including steatosis and inflammation degree *** interaction between miR-103 and the autophagy-related gene phosphatase and tensin homolog(PTEN)was confirmed by dual-luciferase reporter *** role of the interaction between miR-103 and PTEN on autophagy was verified in NASH-like ***,the effects of miR-103 from adipose-derived exosomes on NASH and autophagy were analyzed through animal *** The expression of miR-103 was increased in NASH mice,compared to the control,and inhibition of miR-103 could alleviate *** results of the dual-luciferase reporter assay showed miR-103 could interact with ***-103-anta decreased p-AMPKa,p-mammalian target of rapamycin(mTOR),and p62 but increased the protein levels of PTEN and LC3-II/I and the number of autophagosomes in NASH *** results were also observed in NASH-like cells,and further experiments showed PTEN silencing inhibited the effect of *** derivedexosome miR-103 aggravated NASH and increased the expressions of p-AMPKa,p-mTOR,and p62 but decreased the protein levels of PTEN and LC3-II/I and the number of autophagosomes in ***

关键词： Non-alcoholic steatohepatitis Nonalcoholic fatty liver disease Exosomes Phosphatase and tensin homolog