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Journal of Advanced Ceramics 2024年第5期13卷 641-651页

作者： xi yan Hongjiang Pan Yixin Zhang Tianyu yang yangwei Wang Kun Huang Chongyu Wang Jing Feng Zhenhua Ge Faculty of Materials Science and Engineering Kunming University of Science and TechnologyKunming 650093China

In situ phase separation precipitates play an important role in enhancing the thermoelectric properties of copper sulfides by suppressing phonon transmission.In this study,Cu1.8S composites were fabricated by melting reactions and spark plasma sintering.The complex structures,namely,micron-PbS,Sb_(2)S_(3),nano-FeS,and multiscale pores,originate from the introduction of FePb_(4)Sb_(6)S_(14)into the Cu1.8S matrix.Using effective element(Fe)doping and multiscale precipitates,the Cu_(1.8)S+0.5 wt%FePb_(4)Sb_(6)S_(14)bulk composite reached a high dimensionless figure of merit(ZT)value of 1.1 at 773 K.Furthermore,the modulus obtained for this sample was approximately 40.27 GPa,which was higher than that of the pristine sample.This study provides a novel strategy for realizing heterovalent doping while forming various precipitates via in situ phase separation by natural minerals,which has been proven to be effective in improving the thermoelectric and mechanical performance of copper sulfides and is worth promoting in other thermoelectric systems.

关键词： in situ precipitates jamesonite natural mineral thermoelectric copper sulfides

High-precision parallel computing model of solute transport based on GPU acceleration

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Journal of Hydrodynamics 2024年第1期36卷 202-212页

作者： Shang-hong Zhang Rong-qi Zhang Wen-da Li xi-yan yang yang Zhou School of Water Resources and Hydropower Engineering North China Electric Power UniversityBeijing102206China Hubei Key Laboratory of Intelligent yangtze and Hydroelectric Science China Yangtze Power Co.Ltd.Yichang443133China

The scenario simulation analysis of water environmental emergencies is very important for risk prevention and control,and emergency response.To quickly and accurately simulate the transport and diffusion process of high-intensity pollutants during sudden environmental water pollution events,in this study,a high-precision pollution transport and diffusion model for unstructured grids based on Compute Unified Device Architecture(CUDA)is proposed.The finite volume method of a total variation diminishing limiter with the Kong proposed r-factor is used to reduce numerical diffusion and oscillation errors in the simulation of pollutants under sharp concentration conditions,and graphics processing unit acceleration technology is used to improve computational efficiency.The advection diffusion process of the model is verified numerically using two benchmark cases,and the efficiency of the model is evaluated using an engineering example.The results demonstrate that the model perform well in the simulation of material transport in the presence of sharp concentration.Additionally,it has high computational efficiency.The acceleration ratio is 46 times the single-thread acceleration effect of the original model.The efficiency of the accelerated model meet the requirements of an engineering application,and the rapid early warning and assessment of water pollution accidents is achieved.

关键词： Pollution transport and diffusion model parallel computing Compute Unified Device Architecture(CUDA) pollution event

Rotating Massive Strangeon Stars and X-Ray Plateau of Short GRBs

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Research in Astronomy and Astrophysics 2024年第3期24卷 47-57页

作者： xi-yan yang xiao-Yu Lai Wei-Wei Tan Ren-xin Xu School of Physics and Optoelectronic Engineering Yangtze UniversityJingzhou 434023China Research Center for Astronomy Hubei University of EducationWuhan 4300205China Key Laboratory of Quark and Lepton Physics Central China Normal UniversityMinistry of EducationWuhan 430079China School of Physics Peking UniversityBeijing 100871China Kavli Institute for Astronomy and Astrophysics Peking UniversityBeijing 100871China

Strangeon stars,which are proposed to describe the nature of pulsar-like compact stars,have passed various observational tests.The maximum mass of a non-rotating strangeon star could be high,which implies that the remnants of binary strangeon star mergers could even be long-lived massive strangeon stars.We study rigidly rotating strangeon stars in the slowly rotating approximation,using the Lennard-Jones model for the equation of state.Rotation can significantly increase the maximum mass of strangeon stars with unchanged baryon numbers,enlarging the mass-range of long-lived strangeon stars.During spin-down after merger,the decrease of radius of the remnant will lead to the release of gravitational energy.Taking into account the efficiency of converting the gravitational energy luminosity to the observed X-ray luminosity,we find that the gravitational energy could provide an alternative energy source for the plateau emission of X-ray afterglow.The fitting results of X-ray plateau emission of some short gamma-ray bursts suggest that the magnetic dipole field strength of the remnants can be much smaller than that of expected when the plateau emission is powered only by spin-down luminosity of magnetars.

关键词： dense matter-(stars) pulsars general-(stars) gamma-ray burst general

Parotid metastasis of rare lung adenocarcinoma:A case report

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World Journal of Clinical Cases 2024年第6期12卷 1182-1189页

作者： Ru-xi yan Lin-Bo Dou Zi-Jia Wang Xue Qiao Hong-Hai Ji yan-Cong Zhang School of Stomatology Weifang Medical UniversityWeifang 261000Shandong ProvinceChina Department of Stomatology Dezhou People’s HospitalDezhou 253000Shandong ProvinceChina Department of Stomatology Dezhou Women and Children's HospitalDezhou 253000Shandong ProvinceChina

BACKGROUND Lung cancer(LC)is the leading cause of malignancy-related deaths worldwide.The most common sites of metastasis include the nervous system,bone,liver,respiratory system,and adrenal glands.LC metastasis in the parotid gland is very rare,and its diagnosis presents a challenge.Here,we report a case of parotid metastasis in primary LC.CASE SUMMARY The patient was a 74-year-old male who was discovered to have bilateral facial asymmetry inadvertently two years ago.The right earlobe was slightly swollen and without pain or numbness.Computed tomography(CT)examination showed bilateral lung space-occupying lesions.Pulmonary biopsy was performed and revealed adenocarcinoma(right-upper-lung nodule tissue).Positron emission tomography-CT examination showed:(1)Two hypermetabolic nodules in the right upper lobe of the lung,enlarged hy-permetabolic lymph nodes in the right hilar and mediastinum,and malignant space-occupying lesion in the right upper lobe of the lung and possible metastasis to the right hilar and mediastinal lymph nodes;and(2)multiple hypermetabolic nodules in bilateral parotid glands.Parotid puncture biopsy was performed considering lung adenocarcinoma metastasis.Gene detection of lung biopsy specimens revealed an EGFR gene 21 exon L858R mutation.CONCLUSION This case report highlights the challenging diagnosis of parotid metastasis in LC given its rare nature.Such lesions should be differentiated from primary tumors of the parotid gland.Simple radiological imaging is unreliable,and puncture biopsy is needed for final diagnosis of this condition.

关键词： Lung cancer Metastasis Parotid gland Pathology Positron emission tomography/computed tomography Case report

Acupuncture and moxibustion for irritable bowel syndrome:An umbrella systematic review

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Journal of Integrative Medicine 2024年第1期22卷 22-31页

作者： Yue-ying Ma Zhou Hao Zi-yi Chen yan-xi Shen Hui-rong Liu Huan-gan Wu Chun-hui Bao Shanghai Clinical Research Centre for Acupuncture and Moxibustion Yueyang Hospital of Integrated Chinese and Western MedicineShanghai University of Traditional Chinese MedicineShanghai 200437China Key Laboratory of Acupuncture and Immunological Effects Shanghai University of Traditional Chinese MedicineShanghai 200030China

BackgroundIrritable bowel syndrome(IBS)is a functional bowel disease characterized by abdominal pain or discomfort associated with altered bowel habits.Several clinical studies have demonstrated the effectiveness of acupuncture and moxibustion for IBS.Many systematic reviews of acupuncture and moxibustion for IBS have been published in recent years,but their results are not entirely consistent.ObjectiveTo evaluate the methodological,reporting,and evidence quality of systematic reviews of acupuncture and moxibustion for IBS.Search strategySystematic reviews of acupuncture and moxibustion for IBS published before February 20,2023 were searched in eight databases:PubMed,Embase,Cochrane Library,Web of Science,China National Knowledge Infrastructure,Wanfang Data,VIP Database for Chinese Technical Periodicals,and China Biology Medicine.The keywords used for literature search were acupuncture,moxibustion,systematic review,meta-analysis,and irritable bowel syndrome.Inclusion criteriaSystematic reviews and meta-analyses of randomized controlled trials of acupuncture and moxibustion for IBS were included.Data extraction and analysisRelevant information was independently extracted by two investigators.The A MeaSurement Tool to Assess systematic Reviews 2(AMSTAR 2),Preferred Reporting Items for Systematic Reviews and Meta-Analyses(PRISMA 2020),and Grading of Recommendations Assessment,Development and Evaluation(GRADE)were used to evaluate the methodological quality,reporting quality and evidence quality,respectively.ResultsA total of 342 studies were retrieved and 15 systematic reviews were included.The results of AMSTAR 2 showed low methodological quality in 2 studies and very low methodological quality in the remaining 13 studies,with main issues being failure to register a protocol,incomplete search strategy,not providing a list of excluded studies,incomplete consideration of the risk of bias in the included studies,and a failure to assess the publication bias.The results of PRISMA 2020 showed seriously deficient reportin

关键词： Irritable bowel syndrome Acupuncture Moxibustion Umbrella systematic review Systematic review

Zr-doped titanium lithium ion sieve and EP-granulated composite:Superb adsorption and recycling performance

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Particuology 2022年第10期20卷 100-110页

作者： Suyu Zhou xiaojing Guo xi yan yan Chen Wanzhong Lang The Education Ministry Key Laboratory of Resource Chemistry Shanghai Key Laboratory of Rare Earth Functional MaterialsDepartment of Chemistry and Chemical EngineeringShanghai Normal UniversityShanghai 200234China

Lithium ion sieve(LIS)has attracted great attention due to its high adsorption selectivity towards Li+.Herein,a new type of Zr-doped Ti-LIS(HZrTO)was synthesized by a simple calcination method.The adsorption capacity increased from 56.3 mgg-1(before doping)to 93.2 mgg-1 after doping in LiOH solution(lithium 1.8gL-1).The adsorption isotherm and adsorption kinetics of HZrTO accord with the Langmuir isotherm and the pseudo-second-order kinetic equation,respectively.Batch experiments showed that HZrTO has good stability and selectivity.In addition,HZrTO was granulated via epoxy resin(E-12),and the obtained granular adsorbent showed good adsorption capacity,excellent stability and high selectivity towards Li+.

关键词： Lithium ion sieve Lithium titanium oxide Zr-doped Granulation

Application of mesenchymal stem cell therapy for premature ovarian insufficiency: Recent advances from mechanisms to therapeutics

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World Journal of Stem Cells 2024年第1期16卷 1-6页

作者： Hang-Qi Hu xi-yan xin Yu-Tian Zhu Rui-Wen Fan Hao-Lin Zhang yang Ye Dong Li Department of Traditional Chinese Medicine Peking University Third HospitalBeijing 100191China

The incidence of premature ovarian insufficiency(POI)is increasing worldwide,particularly among younger women,posing a significant challenge to fertility.In addition to menopausal symptoms,POI leads to several complications that profoundly affect female reproductive function and overall health.Unfortunately,current clinical treatment strategies for this condition are limited and often yield unsatisfactory outcomes.These approaches typically involve hormone repla-cement therapy combined with psychological support.Recently,mesenchymal stem cell(MSC)therapies for POI have garnered considerable attention in global research.MSCs can restore ovarian reproductive and endocrine functions through diverse mechanisms,including controlling differentiation,promoting angiogenesis,regulating ovarian fibrosis,inhibiting apoptosis,enhancing autocrine and paracrine effects,suppressing inflammation,modulating the immune system,and genetic regulation.This editorial offers a succinct summary of the application of MSC therapy in the context of POI,providing evidence for groundbreaking medical approaches that have potential to enhance reproductive health and overall well-being for women.

关键词： Mesenchymal stem cell therapy Mechanism Premature ovarian insufficiency Therapeutic Women

Effects of different regional cerebral blood flow on white matter hyperintensity in CADASIL patients

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The Journal of Biomedical Research 2022年第5期36卷 368-374页

作者： Runrun Wang Jiewen Zhang Junkui Shang Fengyu Wang xi yan Department of Neurology Henan Provincial People's HospitalZhengzhou University People's HospitalHenan University People's HospitalZhengzhouHenan 450003China

Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy(CADASIL)is an early-onset inherited small vessel disease.Decreased cerebral blood flow(CBF)may contribute to white matter hyperintensity(WMH)severity in CADASIL,but more evidence is needed to support this hypothesis.This study comprised six patients with CADASIL who harbored mutations in the coding sequence of NOTCH3 and twelve age-matched neurologically healthy controls.We collected clinical and imaging data from patients with CADASIL and divided the brain into four regions:WMH,normal-appearing white matter(NAWM),gray matter(GM),and global brain.We analyzed the relationship between CBF of each region and the WMH volume.Compared with the control group,CBF was significantly decreased in all four regions in the CADASIL group.Lower CBF in these regions was correlated with higher WMH volume in CADASIL.CBF in the NAWM,GM and global regions was positively correlated with that in WMH region.However,after correction tests,only CBF in the WMH region but not in NAWM,GM and global regions was associated with WMH volume.Our findings suggest that CBF in the WMH region is an influencing factor of the WMH severity in CADASIL.

关键词： cerebral hypoperfusion neurovascular unit white matter hyperintensity small vessel disease CADASIL

Mechanisms regulating cerebral hypoperfusion in cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy

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The Journal of Biomedical Research 2022年第5期36卷 353-357页

作者： xi yan Junkui Shang Runrun Wang Fengyu Wang Jiewen Zhang Department of Neurology Henan Provincial People's HospitalZhengzhou University People's HospitalHenan University People's HospitalZhengzhouHenan 450003China

Cerebral small vessel disease (CSVD) is a leading cause of stroke and dementia. As the most common type of inherited CSVD, cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is characterized by the NOTCH3 gene mutation which leads to Notch3 ectodomain deposition and extracellular matrix aggregation around the small vessels. It further causes smooth muscle cell degeneration and small vessel arteriopathy in the central nervous system. Compromised cerebral blood flow occurs in the early stage of CADASIL and is associated with white matter hyperintensity, the typical neuroimaging pathology of CADASIL. This suggests that cerebral hypoperfusion may play an important role in the pathogenesis of CADASIL. However, the mechanistic linkage between NOTCH3 mutation and cerebral hypoperfusion remains unknown. Therefore, in this mini-review, it examines the cellular and molecular mechanisms contributing to cerebral hypoperfusion in CADASIL.

关键词： cerebral hypoperfusion CADASIL Notch3 mural cell astrocyte

Risk factors and predictive model of cerebral edema after road traffic accidents-related traumatic brain injury

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Chinese Journal of Traumatology 2024年第3期27卷 153-162页

作者： Di-You Chen Peng-Fei Wu xi-yan Zhu Wen-Bing Zhao Shi-Feng Shao Jing-Ru xie Dan-Feng Yuan Liang Zhang Kui Li Shu-Nan Wang Hui Zhao Institute for Traffic Medicine Daping HospitalArmy Medical UniversityChongqing400042China Department of Radiology Daping HospitalArmy Medical UniversityChongqing400042China Chongqing Key Laboratory of Traffic Injury and Vehicle Ergonomics Chongqing400042China Wound Trauma Medical Center State Key Laboratory of TraumaBurns and Combined InjuryInstitute of Surgery ResearchDaping HospitalArmy Medical UniversityChongqing.400042China

Purpose:Cerebral edema(CE)is the main secondary injury following traumatic brain injury(TBI)caused by road traffic accidents(RTAs).It is challenging to be predicted timely.In this study,we aimed to develop a prediction model for CE by identifying its risk factors and comparing the timing of edema occurrence in TBI patients with varying levels of injuries.Methods:This case-control study included 218 patients with TBI caused by RTAs.The cohort was divided into CE and non-CE groups,according to CT results within 7 days.Demographic data,imaging data,and clinical data were collected and analyzed.Quantitative variables that follow normal distribution were presented as mean±standard deviation,those that do not follow normal distribution were presented as median(Q1,Q3).Categorical variables were expressed as percentages.The Chi-square test and logistic regression analysis were used to identify risk factors for CE.Logistic curve fitting was performed to predict the time to secondary CE in TBI patients with different levels of injuries.The efficacy of the model was evaluated using the receiver operator characteristic curve.Results:According to the study,almost half(47.3%)of the patients were found to have CE.The risk factors associated with CE were bilateral frontal lobe contusion,unilateral frontal lobe contusion,cerebral contusion,subarachnoid hemorrhage,and abbreviated injury scale(AIS).The odds ratio values for these factors were 7.27(95%confidence interval(CI):2.08-25.42,p=0.002),2.85(95%CI:1.11-7.31,p=0.030),2.62(95%CI:1.12-6.13,p=0.027),2.44(95%CI:1.25-4.76,p=0.009),and 1.5(95%CI:1.10-2.04,p=0.009),respectively.We also observed that patients with mild/moderate TBI(AIS≤3)had a 50%probability of developing CE 19.7 h after injury(χ^(2)=13.82,adjusted R2=0.51),while patients with severe TBI(AIS>3)developed CE after 12.5 h(χ^(2)=18.48,adjusted R2=0.54).Finally,we conducted a receiver operator characteristic curve analysis of CE time,which showed an area under the curve of 0.744 and 0.672 for severe and mild/moderate TBI,

关键词： Road traffic accident Traumatic brain injury Cerebral edema Risk factors Time window