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Computer Modeling in Engineering & Sciences 2024年第8期140卷 1405-1427页

作者： Sen-hui Wang xi Kang Cheng Wang Tian-Bing Ma xiang He Ke Yang School of Mechatronics Engineering Anhui University of Science and TechnologyHuainan232001China Institute of Energy Hefei Comprehensive National Science CenterHefei230031China

Accurately predicting the remaining useful life(RUL)of bearings in mining rotating equipment is vital for mining *** research aims to distinguish the features associated with the RUL of bearings and propose a prediction model based on these selected *** study proposes a hybrid predictive model to assess the RUL of rolling element *** proposed model begins with the pre-processing of bearing vibration signals to reconstruct sixty time-domain *** hybrid model selects relevant features from the sixty time-domain features of the vibration signal by adopting the RReliefF feature selection ***,the extreme learning machine(ELM)approach is applied to develop a predictive model of RUL based on the optimal *** model is trained by optimizing its parameters via the grid search *** training datasets are adjusted to make them most suitable for the regression model using the cross-validation *** proposed hybrid model is analyzed and validated using the vibration data taken from the public XJTU-SY rolling element-bearing *** comparison is constructed with other traditional *** experimental test results demonstrated that the proposed approach can predict the RUL of bearings with a reliable degree of accuracy.

关键词： Bearing degradation remaining useful life estimation RReliefF feature selection extreme learning machine

Long noncoding RNAs HAND2-AS1 ultrasound microbubbles suppress hepatocellular carcinoma progression by regulating the miR-873-5p/tissue inhibitor of matrix metalloproteinase-2 axis

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World Journal of Gastrointestinal Oncology 2024年第4期16卷 1547-1563页

作者： Qiang Zou Hao-Wen Wang xi-Liang Di Yuan Li hui Gao Department of Interventional Therapy Tianjin Medical University Cancer Institute and HospitalTianjin 300060China National Clinical Research Center for Cancer Key Laboratory of Cancer Prevention and TherapyTianjin’s Clinical Research Center for CancerTianjin 300060China College of Animal Science and Technology Northeast Agricultural UniversityHarbin 150030Heilongjiang ProvinceChina Department of Hematology and Oncology Linyi People’s HospitalLinyi 251500Shandong ProvinceChina Department of Comprehensive Oncology Baotou Cancer HospitalBaotou 014030Inner Mongolia Autonomous RegionChina

BACKGROUND Increasing data indicated that long noncoding RNAs(lncRNAs)were directly or indirectly involved in the occurrence and development of tumors,including hepatocellular carcinoma(HCC).Recent studies had found that the expression of lncRNA HAND2-AS1 was downregulated in HCC tissues,but its role in HCC progression is *** targeted microbubble destruction mediated gene transfection is a new method to overexpress *** To study the role of ultrasound microbubbles(UTMBs)mediated HAND2-AS1 in the progression of HCC,in order to provide a new reference for the treatment of *** In vitro,we transfected HAND2-AS1 siRNA into HepG2 cells by UTMBs,and detected cell proliferation,apoptosis,invasion and epithelial-mesenchymal transition(EMT)by cell counting kit-8 assay,flow cytometry,Transwell invasion assay and Western blotting,*** addition,we transfected miR-837-5p mimic into UTMBs treated cells and observed the changes of cell ***,the UTMBs treated HepG2 cells were transfected together with miR-837-5p mimic and tissue inhibitor of matrix metalloproteinase-2(TIMP2)overexpression vector,and we detected cell proliferation,apoptosis,invasion and *** vivo,we established a mouse model of subcutaneous transplantation of HepG2 cells and observed the effect of HAND2-AS1 silencing on tumor formation *** We found that UTMBs carrying HAND2-AS1 restricted cell proliferation,invasion,and EMT,encouraged apoptosis,and HAND2-AS1 silencing eliminated the effect of ***,miR-873-5p targets the gene HAND2-AS1,which also targets the 3’UTR of *** miR-873-5p mimic counteracted the impact of ***,miR-873-5p mimic solely or in combination with pcDNA-TIMP2 had been transformed into HepG2 cells exposed to *** discovered that TIMP2 reversed the effect of miR-873-5p mimic caused by the blocked signalling cascade for matrix metalloproteinase(MMP)2/*** vivo results showed that HAND2-AS1 silencing sig

关键词： Hepatocellular carcinoma Ultrasound microbubbles Long noncoding RNA HAND2-AS1 miR-873-5p Tissue inhibitor of matrix metalloproteinase-2

Automatic Generation Control in a Distributed Power Grid Based on Multi-step Reinforcement Learning

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Protection and Control of Modern Power Systems 2024年第4期9卷 39-50页

作者： Wenmeng Zhao Tuo Zeng Zhihong Liu Lihui xie Lei xi hui Ma the Electric Power Research Institute Southern Power GridGuangzhou 510663China the Heyuan Power Supply Bureau Guang-dong Power Grid Co.Ltd.Heyuan 517000China the College of Electrical Engineering&New Energy China Three Gorges UniversityYichang 443002China the College of Electrical Engineering&New Energy and Hubei Provincial Key Laboratory for Operation and Control of Cascaded Hydropower Station China Three Gorges UniversityYichang 443002China IEEE

The increasing use of renewable energy in the power system results in strong stochastic disturbances and degrades the control performance of the distributed power *** this paper,a novel multi-agent collaborative reinforcement learning algorithm is proposed with automatic optimization,namely,Dyna-DQL,to quickly achieve an optimal coordination solution for the multi-area distributed power *** proposed Dyna framework is combined with double Q-learning to collect and store the environmental *** can iteratively update the agents through buffer replay and real-time *** the environmental data can be fully used to enhance the learning speed of the *** mitigates the negative impact of heavy stochastic disturbances caused by the integration of renewable energy on the control *** are conducted on two different models to validate the effectiveness of the proposed *** results demonstrate that the proposed Dyna-DQL algorithm exhibits superior stability and robustness compared to other reinforcement learning algorithms.

关键词： Automatic generation control Dyna framework distributed power grid multi-agent mod-el-based reinforcement learning

九味镇心颗粒结合舍曲林对伴非自杀性自伤青少年抑郁症患者抑郁情绪、自伤水平及冲动行为的影响

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临床和实验医学杂志 2024年第17期23卷 1864-1868页

作者：王旭光陈兴隆万喜慧孙立东周海卢立明潍坊市精神卫生中心精神科山东潍坊261000

目的观察九味镇心颗粒结合舍曲林对伴非自杀性自伤青少年抑郁症患者抑郁情绪、自伤水平及冲动行为的影响。方法前瞻性选取2022年1月至2023年2月潍坊市精神卫生中心收治的65例伴非自杀性自伤青少年抑郁症患者,按照奇偶数分组法分为舍... 详细信息

目的观察九味镇心颗粒结合舍曲林对伴非自杀性自伤青少年抑郁症患者抑郁情绪、自伤水平及冲动行为的影响。方法前瞻性选取2022年1月至2023年2月潍坊市精神卫生中心收治的65例伴非自杀性自伤青少年抑郁症患者,按照奇偶数分组法分为舍曲林组(n=32)和联合组(n=33)。舍曲林组给予舍曲林治疗,联合组给予九味镇心颗粒结合舍曲林治疗。两组疗程均为8周。评估并比较两组治疗前和治疗8周后的自我伤害行为筛选量表评分、情绪调节困难量表(DERS)评分、汉密尔顿抑郁量表(HAMD)评分、抑郁自评量表(SDS)评分、Barratt冲动量表(BIS-II)评分差异,检测两组治疗前和治疗8周后的神经递质(5-羟色胺、P物质、皮质醇)水平,记录并比较两组不良反应。结果治疗8周后,联合组的忧郁孤独、自残自杀、退缩与自我批评及总分分别为(5.82±1.47)、(2.56±0.78)、(2.95±0.95)、(15.57±3.11)分,均低于舍曲林组[(7.95±1.89)、(4.25±1.06)、(3.57±1.24)、(20.03±3.56)分],差异均有统计学意义(P0.05)。治疗8周后,联合组的HAMD评分、SDS评分、DERS评分、BIS-Ⅱ评分分别为(11.74±3.04)、(28.78±4.12)、(105.85±15.43)、(24.17±3.86)分,均低于舍曲林组[(15.45±3.56)、(39.45±4.56)、(114.56±14.62)、(27.23±4.11)分],差异均有统计学意义(P0.05)。结论九味镇心颗粒结合舍曲林可减轻伴非自杀性自伤青少年抑郁症患者抑郁情绪,减轻自伤和冲动行为,可能与调节神经递质有关。

关键词：九味镇心颗粒舍曲林非自杀性自伤抑郁症自伤冲动行为

EFFECT OF RARE EARTH METALS ON Cu-BASED LOW ALCOHOL SYNTHESIS CATALYSTS

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Journal of Energy Chemistry 1995年第2期 178-185页

作者： KANG hui-Min CHEN Bao-ShuWANG Da-xiang KANG xi-hui ZHAO Jiu-ShengChemical Engineering Department, Tianjin University Tuianjin 300072

Rare earth metals （RE metal ） such as La and Ce are selected aspromoters in the Cu-based low alcohol synthesis catalysts. Their effects on thecatalyst structure and performance are studied. Promoters La and Ce have thetrend to form a network-like structure on the catalyst surface with result ofstabilizing the Cu crystallites on it and prohibiting them from sintering at hightemperature. RE metal has also the property of compensating the decreasingeffect of promoter potassium on its surface area. As a result, the introductionof RE metul to the Cu-based low alcohol synthesis catalyst can improve itsthermal stability and increase its selectivity to Calcohols.

关键词： catalysts low alcohols rare earth metals

Fast-response,high-sensitivity multi-modal tactile sensors based on PPy/Ti_(3)C_(2)T_(x) films for multifunctional applications

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Nano Research 2024年第5期17卷 4410-4419页

作者： Guangshuai xi Dongzhi Zhang Mingcong Tang Hao Zhang Yuehang Sun Yubiao Zhang Haolin Cai hui xia Dandi Zhou College of Control Science and Engineering China University of Petroleum(East China)Qingdao 266580China

In recent years,multi-modal flexible tactile sensors have become an important direction in the development of electronic skin because of their excellent sensitivity,flexibility and wearable *** this work,a humidity-pressure multi-modal flexible sensor based on polypyrrole(PPy)/Ti_(3)C_(2)T_(x) sensitive film packaged with porous polydimethylsiloxane(PDMS)is investigated by combining the sensitive structure generation mechanism of in situ polymerization to achieve the simultaneous detection of humidity and pressure,which has a sensitivity of 89,113.4Ω/%RH in a large humidity range of 0%-97%RH,and response/recovery time of 2.5/1.9 *** tactile pressure sensing has a high sensitivity,a fast response of 67/52 ms,and a wide detection *** device also has excellent performance in terms of stability and repeatability,making it promising for respiratory pattern and motion *** work provides a new solution to address the construction of multi-modal tactile sensors with potential applications in the fields of medical health,epidemic prevention.

关键词： multi-modal sensors humidity-pressure tactile sensors resistive sensors Ti3C2Tx human respiratory and motion detection

Tuning the membrane rejection behavior by surface wettability engineering for an effective water-in-oil emulsion separation

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Chinese Chemical Letters 2024年第6期35卷 480-485页

作者： Yan Zou Yin-Shuang Hu Deng-hui Tian Hong Wu xiaoshu Lv Guangming Jiang Yu-xi Huang Engineering Research Center for Waste Oil Recovery Technology and Equipment Ministry of EducationChongqing Technology and Business UniversityChongqing 400067China School of Environmental Science and Engineering Sun Yat-sen UniversityGuangzhou 510275China Guangdong Provincial Key Laboratory of Environmental Pollution Control and Remediation Technology(Sun Yat-sen University) Guangzhou 510275China

Membrane-based separation is a promising technology to eliminate water impurities from the oil ***,it remains a great challenge to separate water from highly emulsified viscous oil owing to the high stability of the water droplets in *** we report a surface wettability engineering on an alumina ceramic membrane to achieve an efficient separation of a water-in-oil(W/O)*** with different carbon chain lengths and fluorinated status were introduced to endow the alumina membrane with different surface *** all the modified membranes exhibited excellent separation of the W/O without Span 80(surfactant),the one with amphiphobic wettability and lowest surface energy failed to separate the Span 80 stabilized W/*** presence of Span 80 reduced the interfacial tension of water droplets,making them easier to deform and penetrate the modified membrane with the lowest surface *** reveals that engineering proper surface wettability is the key to separating the oil and water ***,the modified membranes maintained decent separation performance and stability under long-term run separation of the emulsified W/O.

关键词： Water-in-oil emulsion Ceramic membrane Membrane separation Surface wettability

A NAC transcription factor MNAC3-centered regulatory network negatively modulates rice immunity against blast disease

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Journal of Integrative Plant Biology 2024年第9期66卷 2017-2041页

作者： hui Wang Yan Bi Yuqing Yan xi Yuan Yizhou Gao Muhammad Noman Dayong Li Fengming Song National Key Laboratory for Rice Biology and Breeding Institute of BiotechnologyZhejiang UniversityHangzhou 310058China Ministry of Agriculture Key Laboratory of Molecular Biology of Crop Pathogens and Insect Pests Institute of BiotechnologyZhejiang UniversityHangzhou 310058China Key Laboratory of Biology of Crop Pathogens and Insects of Zhejiang Province Institute of BiotechnologyZhejiang UniversityHangzhou 310058China College of Chemistry and Life Sciences Zhejiang Normal UniversityJinhua 321004China

NAC transcription factors(TFs)are pivotal in plant immunity against diverse ***,we report the functional and regulatory network of MNAC3,a novel NAC TF,in rice ***3,a transcriptional activator,negatively modulates rice immunity against blast and bacterial leaf blight diseases and pathogen-associated molecular pattern(PAMP)-triggered immune ***3 binds to a CACG cis-element and activates the transcription of immune-negative target genes OsINO80,OsJAZ10,and *** negative function of MNAC3 in rice immunity depends on its transcription of downstream genes such as OsINO80 and ***3 interacts with immunity-related OsPP2C41(a protein phosphatase),ONAC066(a NAC TF),and OsDjA6(a DnaJ chaperone).ONAC066 and OsPP2C41 attenuate MNAC3 transcriptional activity,while OsDjA6 promotes *** of MNAC3 at S163 is critical for its negative functions in rice ***2C41,which plays positive roles in rice blast resistance and chitin-triggered immune responses,dephosphorylates MNAC3,suppressing its transcriptional activity on the target genes OsINO80,OsJAZ10,and OsJAZ11 and promoting the translocation of MNAC3 from nucleus to *** results establish a MNAC3-centered regulatory network in which OsPP2C41 dephosphorylates MNAC3,attenuating its transcriptional activity on downstream immune-negative target genes in ***,these findings deepen our understanding of molecular mechanisms in rice immunity and offer a novel strategy for genetic improvement of rice disease resistance.

关键词： NAC transcription factor MNAC3 OsINO80 OsJAZ10 OsJAZ11 protein phosphatase OsPP2C41 rice immunity

THE COKING PROPERTIES AND STATES OF AN INDUSTRIAL W-Ni USED CATALYST

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Chinese Chemical Letters 1991年第12期2卷 963-966页

作者： Ji Gang LUO Chen Lie LI Ming Shi LI Yan ZHO xi hui LUO Chemical and Technology University of East China Shanghai200237 Fushun Research Institute of Petroleum and Petrochemicals FushunLianing113001

PASCA, ESR and Microreactor, have been used to study the states and properties of coking deposits on catalyst. The results indicate that the C exists as three types of states on catalyst surface. The first and second types of carbon are the main reason of the catalyst deactivation, but the third type has a promoting role in n-C_7 hydrocracking reaction. The S_s-C interacts strongly with catalyst, forming metal-carbon-support interaction (MCSI).

关键词： Th THE COKING PROPERTIES AND STATES OF AN INDUSTRIAL W-Ni USED CATALYST PASCA DC Ni

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平原地区林场森林防灭火规划性建议

森林防火 2024年第1期42卷 43-46页

作者：林存雷李静张琳石杰陈月民耿玉军周西会莘县自然资源和规划局山东聊城252400

介绍了平原林场形成特点,梳理了平原林场森林防火存在问题和管理弊端,针对这些问题和弊端提出了平原林场森林防火建议,以期为有效减少平原林场森林火灾提供借鉴。

关键词：森林防火平原林场安全隐患问题规划性建议