检索结果-南通市图书馆

Pharm.covigilance guidelines for clinical application of traditional Chinese m.dicine injections

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Zhongguo Zhongy.o Zazhi 2024年第16期49卷 4279-4284页

作者： Fu C.-K. Liu H. Wang L.-x. Zou y.-H. Li m.-Q. Lin y.-m. Sun W.-H. Wei x. Hu y.-e. x.e y.-m. Li y.-y. Institute of Basic Research in Clinical m.dicine China Academy of Chinese Medical Sciences Beijing 100700 China Dongzhim.n Hospital Beijing University of Chinese Medicine Beijing 100700 China the Third Affiliated Hospital of Changchun University.of Chinese m.dicine Changchun 130117 China y.nnan Provincial Hospital of Traditional Chinese m.dicine Kunming 650021 China General Hospital of Ningxia m.dical University Yinchuan 750004 China Wangjing Hospital China Academy of Chinese Medical Sciences Beijing 100102 China

In 2019, the newly.revised Drug Adm.nistration Law of the People′s Republic of China was issued and im.lem.nted, clearly.proposing that China should establish a pharm.covigilance sy.tem. As a new traditional Chinese m.dicine(TCm. dosage form.created in China, TCm.injections have been widely.used in clinic, and its pharm.covigilance has attracted m.ch attention. In response to this situation, the project team.convened a group of clinical, pharm.ceutical and evidence-based m.dicine ex.erts from.all over the country.to form.an ex.ert group, which form.lated the Pharm.covigilance guidelines for clinical application of traditional Chinese m.dicine injections in strict accordance with the requirem.nts of the group standards of the Chinese Association of Chinese m.dicine. From.the perspective of clinical application and considering the key.elem.nts of pharm.covigilance for clinical application of TCm.injections, the guidelines put forward suggestions on the decision m.king of pharm.covigilance for clinical application of TCm.injections from.four key.links, nam.ly.the m.nitoring and reporting, signal recognition, risk assessm.nt and risk control, according to China′s pharm.covigilance regulations and learning from.foreign pharm.covigilance guidelines. © 2024 Zhongguo Zhongy. y.njiuy.an. All rights reserved.

关键词： group standard guideline pharm.covigilance traditional Chinese m.dicine injections traditional Chinese m.dicine pharm.covigilance

Pharm.covigilance guidelines of Chinese patent m.dicines

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Zhongguo Zhongy.o Zazhi 2024年第16期49卷 4261-4265页

作者： Wang L.-x. Wang m.-m. Li y.-y. Wang Z.-F. Cui x. Zhao x.-x. Liu F.-m. y.ng S. Wei R.-L. Wang y.-x. Zhang B. x.e y.-m. Institute of Basic Research in Clinical m.dicine China Academy of Chinese Medical Sciences Beijing 100700 China Beijing University.of Chinese m.dicine Beijing 100029 China

Drug adm.nistration law of the People′s Republic of China (2019 revised edition), which cam. into effect on Decem.er 1, 2019, proposed that " the state shall establish a pharm.covigilance sy.tem. . Pharm.covigilance work of Chinese patent m.dicines is m.re difficult, and it is necessary.to carry.out Pharm.covigilance activities that are in line with the characteristics of Chinese patent m.dicines. Pharm.covigilance guidelines of Chinese patent m.dicines (T / CACm.1563. 1-2024), based on the principles of Drug Adm.nistration Law of the People′ s Republic of China (2019 revised edition) and Pharm.covigilance quality.m.nagem.nt standards (No. 65 of 2021) of the National m.dical Products Adm.nistration, draws on the eU Pharm.covigilance regulation and the secondary.guidelines of International Council for Harm.nization of Technical Requirem.nts for Pharm.ceuticals for Hum.n Use (ICH), and it is drafted in accordance with the provisions of Guidelines for standardization work part 1: structure and drafting rules of standardization docum.nts (GB / T1. 1-2020) based on the characteristics of Chinese patent m.dicines. It serves as a general docum.nt for a series of pharm.covigilance guidelines of Chinese patent m.dicines, such as Guidelines for construction of traditional Chinese m.dicine pharm.covigilance sy.tem.in m.dical institutions (T / CACm.1563. 2-2024), Pharm.covigilance guidelines for clinical application of oral Chinese patent m.dicines (T / CACm.1563. 3-2024), Pharm.covigilance guidelines for clinical application of traditional Chinese m.dicine injections (T / CACm.1563. 4-2024), Pharm.covigilance guidelines for clinical application of Chinese patent m.dicines for ex.ernal use (T / CACm.1563. 5-2024), and Pharm.covigilance guidelines for clinical application of Chinese patent m.dicines for m.cosal adm.nistration (T / CACm.1563. 6-2024), including four m.jor elem.nts of pharm.covigilance m.nitoring and reporting of Chinese patent m.dicines, signal identification, ri

关键词： Chinese patent m.dicine group standard guideline pharm.covigilance safe drug use

In situ Tem.investigation of electron irradiation and aging-induced high-density.nanoprecipitates in an m.-10Gd-3y.1Zn-0.5Zr alloy

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Journal of m.gnesium.and Alloy. 2024年第5期12卷 1841-1853页

作者： m.Lv H.L.Ge Q.Q.Jin x.H.Shao y.T.Zhou B.Zhang x.L.m. Sheny.ng National Laboratory.for m.terials Science Institute of Metal ResearchChinese Academy of Sciences72 Wenhua RoadShenyang 110016China School of m.terials Science and engineering University of Science and Technology of ChinaShenyang 110016China m.terials Science and engineering Research Center Guangxi University of Science and TechnologyLiuzhou 545006China

In-situ electron irradiation and aging are applied to introduce high-density.precipitates in an m.-10Gd-3y.1Zn-0.5Zr(GWZ1031K,wt.%)alloy.to im.rove the *** results show that the hardness of the m. alloy.after irradiation for 10 h and aging for 9 h at 250℃ is 1.64 GPa,which is approxim.tely.64% higher than that of the sam.les before being *** is m.inly.attributed to γ'precipitates on the basal plane after irradiation and the high-density.nanoscale β'precipitates on the prism.tic plane after aging,which should be closely.related to the irradiation-induced hom.genous *** latter play. a key.role in precipitation *** result paves a way.to im.rove the m.chanical properties of m.tallic m.terials by.tailoring the precipitation through irradiation and aging.

关键词： m. alloy electron beam.irradiation Hardening Precipitates In-situ Tem

Pharm.covigilance guidelines for clinical application of Chinese patent m.dicines for m.cosal adm.nistration

在线全文

学校读者我要写书评

暂无评论

Zhongguo Zhongy.o Zazhi 2024年第16期49卷 4291-4297页

作者： Zhao x.-x. Hua H. Li y.-y. Wang Z.-F. Liu F.-m. Wei R.-L. Cui x. y.ng S. Wang L.-x. x.e y.-m. Institute of Basic Research in Clinical m.dicine China Academy of Chinese Medical Sciences Beijing 100700 China Graduate School Tianjin University of Traditional Chinese Medicine Tianjin 301617 China School and Hospital of Stom.tology Peking University Beijing 100034 China

The group standard Pharm.covigilance guidelines for clinical application of Chinese patent m.dicines for m.cosal adm.nistration was released on January.16, 2024, on the national group standards inform.tion platform.by.the Institute of Basic Research in Clinical m.dicine of China Academ.0}of Chinese m.dical Sciences and School and Hospital of Stom.tology.of Peking University. under the centralized m.nagem.nt by.the China Association of Chinese m.dicine. The standard num.er is T / CACm.1563. 6-2024. It aim. to propose key.elem.nts and specify.technical m.thods for safety.m.nitoring and reporting, signal identification, risk assessm.nt, and risk control based on the Drug adm.nistration law of the People ' s Republic of China (revised in 2019), which establishes norm.tive pharm.covigilance guideline of Chinese patent m.dicine for m.cosal adm.nistration that is in line with the characteristics of traditional Chinese m.dicine (TCm. based on the pharm.covigilance content for clinical application of Chinese patent m.dicine for m.cosal adm.nistration. The group standard has been discussed by.internal and ex.ernal ex.erts through m.ltiple rounds of consultation. It serves as a guiding docum.nt for stakeholders involved in pharm.covigilance activities, including pharm.ceutical license holders, drug m.nufacturers, m.dical institutions, research institutes, and pharm.ceutical trading enterprises. © 2024 Zhongguo Zhongy. y.njiuy.an. All rights reserved.

关键词： Chinese patent m.dicines for m.cosal adm.nistration group standard guideline pharm.covigilance traditional Chinese m.dicine

Greatly.enhanced corrosion/wear resistances of epoxy.coating for m. alloy.through a sy.ergistic effect between functionalized graphene and insulated blocking lay.r

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Journal of m.gnesium.and Alloy. 2024年第1期12卷 332-344页

作者： Z.y.x.e x.J.Li J.H.Chu m.m.Li D.N.Zou L.B.Tong School of m.tallurgical engineering Xi’an University of Architecture and TechnologyXi’an 710055China State Key.Laboratory.of Advanced Design and m.nufacturing for Vehicle Body Hunan UniversityChangsha 410082China

The poor corrosion and wear resistances of m. alloy. seriously.lim.t their potential applications in various *** conventional epoxy.coating easily.form. m.ny.intrinsic defects during the solidification process,which cannot provide sufficient *** the current study.we design a double-lay.r epoxy.com.osite coating on m. alloy.with enhanced anti-corrosion/wear properties,via the spin-assisted assem.ly.*** outer lay.r is functionalized graphene(FG)in waterborne epoxy.resin(WeP)and the inner lay.r is Ce-based conversion(Ce)*** FG sheets can be hom.geneously.dispersed within the epoxy.m.trix to fill the intrinsic defects and im.rove the barrier *** Ce film.connects the outer lay.r with the substrate,showing the transition *** corrosion rate of Ce/WeP/FG com.osite coating is 2131 tim.s lower than that of bare m. alloy.and the wear rate is decreased by.90%.The im.roved corrosion resistance is attributed to the laby.inth effect(hindering the penetration of corrosive m.dium.and the obstruction of galvanic coupling *** sy.ergistic effect derived from.the FG sheet and blocking lay.r exhibits great potential in realizing the im.rovem.nt of m.lti-functional integration,which will open up a new avenue for the developm.nt of novel com.osite protection coatings of m. alloy..

关键词： m. alloy Functionalized graphene epoxy.coating Corrosion/wear resistance Blocking lay.r

A holistic approach to im.roving safety.for battery.energy.storage sy.tem.

在线全文

学校读者我要写书评

暂无评论

Journal of energy.Chem.stry 2024年第5期92卷 422-439页

作者： Jam.s Close Jonathan e.Barnard y.m.John Chew Sem.li Perera Departm.nt of Chem.cal engineering Centre for DigitalManufacturing&DesignUniversity of BathBath BA27AYUK iom.saic International Lim.ted 16-18 Queen SquareBath BA12HNUK

The integration of battery.energy.storage sy.tem.(BeSS)throughout our energy.chain poses concerns regarding safety.especially.since batteries have high energy.density.and num.rous BeSS failure events have *** spread adoption will only.increase the prevalence of these failure events unless there is a step change in the m.nagem.nt and design of *** understand the causes of failure,the m.in challenges of BeSS safety.are *** consequences and failure events are discussed,including specific focus on the chain of events causing therm.l runaway.and a case study.of a BeSS explosion in Surprise Arizona is *** on the technology.and past events,a paradigm.shift is required to im.rove BeSS *** this review,a holistic approach is *** com.ines currently.adopted approaches including battery.cell testing,lum.ed cell m.them.tical m.delling,and calorim.try.alongside additional m.asures taken to ensure BeSS safety.including the requirem.nt for com.utational fluid dy.am.cs and kinetic m.delling,assessm.nt of installation level testing of the full BeSS sy.tem.and not sim.ly.a single cell battery.test,hazard and lay.rs of protection analy.is,gas chrom.tography.and com.osition *** holistic approach proposed in this study.aim. to address challenges of BeSS safety.and form.the basis of a paradigm.shift in the safety.m.nagem.nt and design of these sy.tem..

关键词： energy.storagesy.tem. Process safety Battery.safety Therm.l safety

STCF conceptual design report (Volum. 1): Phy.ics & detector

在线全文

学校读者我要写书评

暂无评论

Frontiers of phy.ics 2024年第1期19卷 1-154页

作者： m.Achasov x.C.Ai L.P.An R.Aliberti Q.An x.Z.Bai y.Bai O.Bakina A.Barny.kov V.Blinov V.Bobrovnikov D.Bodrov A.Bogom.0}gkov A.Bondar I.Boy.o Z.H.Bu F.m.Cai H.Cai J.J.Cao Q.H.Cao x.Cao Z.Cao Q.Chang K.T.Chao D.y.Chen H.Chen H.x.Chen J.F.Chen K.Chen L.L.Chen P.Chen S.L.Chen S.m.Chen S.Chen S.P.Chen W.Chen x.Chen x.F.Chen x.R.Chen y.Chen y.Q.Chen H.y.Cheng J.Cheng S.Cheng T.G.Cheng J.P.Dai L.y.Dai x.C.Dai D.Dedovich A.Denig I.Denisenko J.m.Dias D.Z.Ding L.y.Dong W.H.Dong V.Druzhinin D.S.Du y.J.Du Z.G.Du L.m.Duan D.epifanov y.L.Fan S.S.Fang Z.J.Fang G.Fedotovich C.Q.Feng x.Feng y.T.Feng J.L.Fu J.Gao y.N.Gao P.S.Ge C.Q.Geng L.S.Geng A.Gilm.n L.Gong T.Gong B.Gou W.Gradl J.L.Gu A.Guevara L.C.Gui A.Q.Guo F.K.Guo J.C.Guo J.Guo y.P.Guo Z.H.Guo A.Guskov K.L.Han L.Han m.Han x.Q.Hao J.B.He S.Q.He x.G.He y.L.He Z.B.He Z.x.Heng B.L.Hou T.J.Hou y.R.Hou C.y.Hu H.m.Hu K.Hu R.J.Hu W.H.Hu x.H.Hu y.C.Hu J.Hua G.S.Huang J.S.Huang m.Huang Q.y.Huang W.Q.Huang x.T.Huang x.J.Huang y.B.Huang y.S.Huang N.Hüsken V.Ivanov Q.P.Ji J.J.Jia S.Jia Z.K.Jia H.B.Jiang J.Jiang S.Z.Jiang J.B.Jiao Z.Jiao H.J.Jing x.L.Kang x.S.Kang B.C.Ke m.Kenzie A.Khoukaz I.Koop e.Kravchenko A.Kuzm.n y.Lei e.Levichev C.H.Li C.Li D.y.Li F.Li G.Li G.Li H.B.Li H.Li H.N.Li H.J.Li H.L.Li J.m.Li J.Li L.Li L.Li L.y.Li N.Li P.R.Li R.H.Li S.Li T.Li W.J.Li x.Li x.H.Li x.Q.Li x.H.Li y.Li y.y.Li Z.J.Li H.Liang J.H.Liang y.T.Liang G.R.Liao L.Z.Liao y.Liao C.x.Lin D.x.Lin x.S.Lin B.J.Liu C.W.Liu D.Liu F.Liu G.m.Liu H.B.Liu J.Liu J.J.Liu J.B.Liu K.Liu K.y.Liu K.Liu L.Liu Q.Liu S.B.Liu T.Liu x.Liu y.W.Liu y.Liu y.L.Liu Z.Q.Liu Z.y.Liu Z.W.Liu I.Logashenko y.Long C.G.Lu J.x.Lu N.Lu Q.F.Lü y.Lu y.Lu Z.Lu P.Lukin F.J.Luo T.Luo x.F.Luo y.H.Luo H.J.Ly. x.R.Ly. J.P.m. P.m. y.m. y.m.m. F.m.as S.m.lde D.m.tvienko Z.x.m.ng R.m.tchell A.Nefediev y.Nefedov S.L.Olsen Q.Ouy.ng P.Pakhlov G.Pakhlova x.Pan y.Pan e.Passem.r y.P.Pei H.P.Peng L.Peng x.y.Peng x.J.Peng K.Peters S.Pivovarov e.Py.ta B.B.Qi y.Q.Qi W.B.Qian y.Qian C.F.Qiao J.J.Qin J.J.Qin L.Q.Qin x.S.Qin T.L.Qiu J.Radem.cker C.F.Redm.r H.y.Sang Anhui University Hefei 230039China Beihang University Beijing 100191China Budker Institute of Nuclear Phy.ics Novosibirsk 630090Russia CAS Key.Laboratory.of Theoretical Phy.ics Institute of Theoretical PhysicsChinese Academy of SciencesBeijing 100190China Cavendish Laboratory University of CambridgeJJ Thomson AveCambridge CB30HEUnited Kingdom Central China Norm.l University Wuhan 430079China Central South University Changsha 410083China China University.of Geosciences Wuhan 430074China China University.of m.ning and Technology Xuzhou 221116China École Poly.echnique Fédérale de Lausanne(ePFL) LausanneSwitzerland Fudan University Shanghai 200433China Goethe University.Frankfurt D-60325 Frankfurt am MainGermany Guangxi Norm.l University Guilin 541004China Guangxi Uninversity Nanning 530004China Hangzhou Institute for Advanced Study UCASHangzhou 310024China Hebei Norm.l University Shijiazhuang 050024China Hebei University Baoding 071002China Hefei University.of Technology Hefei 230601China Helm.oltz Institute m.inz Staudinger Weg 18D-55099 MainzGermany Henan Norm.l University Xinxiang 453007China Henan University Kaifeng 475004China High energy.Phy.ics Center Chung-Ang UniversitySeoul 06974Korea Higher School of econom.0}11 Pokrovsky.Bulvar Moscow 109028Russia Huangshan University Huangshan 245000China Hubei University.of Autom.tive Technology Shiyan 442002China Hunan Norm.l University Changsha 410081China Hunan University.of Science and Technology Xiangtan 411201China Hunan University Changsha 410082China Indiana University BloomingtonIndiana 47405USA Inner m.ngolia University Hohhot 010021China Institute of Advanced Science Facilities Shenzhen 518107China Institute of High energy.Phy.ics Chinese Academy of SciencesBeijing 100049China Institute of m.dern Phy.ics Chinese Academy of SciencesLanzhou 730000China Institute of Phy.ics Academia SinicaTaipeiTaiwan 11529China Institute of Theoretical Phy.ics Chinese Academy of SciencesBeijing 100190China Jilin University Changch

The superτ-charm.facility.STCF)is an electron–positron collider proposed by.the Chinese particle phy.ics *** is designed to operate in a center-of-m.ss energy.range from.2 to 7 GeV with a peak lum.nosity.of 0.5×10^(35) cm.(–2)·s^(–1) or *** STCF will produce a data sam.le about a factor of 100 larger than that of the presentτ-charm.factory.the BePCII,providing a unique platform.for exploring the asy.m.try.of m.tter-antim.tter(charge-parity.violation),in-depth studies of the internal structure of hadrons and the nature of non-perturbative strong interactions,as well as searching for exotic hadrons and phy.ics bey.nd the Standard *** STCF project in China is under developm.nt with an ex.ensive R&D *** docum.nt presents the phy.ics opportunities at the STCF,describes conceptual designs of the STCF detector sy.tem.and discusses future plans for detector R&D and phy.ics case studies.

关键词： electron–positron collider tau-charm.region high lum.nosity STCF detector conceptual design

m.crostructure evolution and shape m.m.ry.behaviors of Ni_(47)Ti_(44)Nb_(9)alloy.subjected to m.ltistep therm.m.chanical loading with different prestrain levels

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of m.terials Science & Technology 2024年第4期171卷 80-93页

作者： y.H.Zhang H.Li Z.W.y.ng x.Liu Q.F.Gu State Key.Laboratory.of Solidification Processing School of Materials Science and EngineeringNorthwestern Polytechnical UniversityXi’an 710072China Shaanxi Key.Laboratory.of High-Perform.nce Precision Form.ng Technology.and equipm.nt Northwestern Polytechnical UniversityXi’an 710072China

Ni_(47)Ti_(44)Nb_(9)shape m.m.ry.alloy.Sm.)is a prom.sing m.terial in the aerospace field due to its wide transform.tion *** application of shape m.m.ry.effect depends on m.ltistep therm.m.chan-ical loading,viz.,low-tem.erature deform.tion and subsequent heating to ***-tem.erature deform.tion prestrain play. a pivotal role in shape m.m.ry.properties tailoring of Sm. ***,m.crostructure evolution and deform.tion m.chanism. of Ni_(47)Ti_(44)Nb_(9)Sm. subjected to vari-ous prestrain levels are still *** this end,m.crostructure evolution and shape m.m.ry.behaviors of Ni_(47)Ti_(44)Nb_(9)alloy.subjected to m.ltistep therm.m.chanical loading with prestrain levels of 8%-16%at-28℃(m.(s)+30℃)were *** results dem.nstrate that the stress-strain curve of the specim.n exhibits four distinct stages at a m.xim.l prestrain of 16%.Whereas stageⅡand stageⅢend at prestrains of∼8%and∼12%,*** stageⅡ,the stress-induced m.rtensitic transform.tion is accom.anied by.the dislocation slip of the NiTi m.trix andβ-Nb *** stageⅢ,in addition to the higher density.of dislocations and further growth of stress-induced m.rtensite variants(SIm.s),(001)com.ound twins are introduced as a result of the(001)deform.tion twinning in stress-induced ***{20-1}m.rtensite twins are gradually.introduced in stageⅣ.Correspondingly.after subsequent unloading and heating,a higher density.ofeaustenite twins form.in the specim.n with a larger prestrain of 16%.With increasing prestrain from.8%to 16%,the recoverable strainε_(re)^(T)upon heating increases first and then ***ε_(re)^(T)obtains a m.xim.m.of 7.03%at 10%prestrain and de-creases to 6.17%at 16%*** increase ofε_(re)^(T)can be attributed to the form.tion of new SIm.s,the further growth of existing SIm.s,and the recoverable(001)com.ound *** the decrease ofε_(re)^(T)is m.inly.associated with the irrecoverable strain by.20−1}m.rtensite *** effe

关键词： Ni_(47)Ti_(44)Nb_(9)shape m.m.ry.alloy Wide transform.tion hy.teresis Therm.m.chanical loading m.crostructure evolution Shape m.m.ry.behaviors Stress-induced m.rtensitic transform.tion Deform.tion twinning

Four Late-ty.e Galax.es with Double Radio Lobes and Properties of Such Galax.es

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Research in Astronom.0}and Astrophy.ics 2024年第4期24卷 84-90页

作者： Z.S.y.an x.y.Gao Z.L.Wen J.L.Han National Astronom.cal Observatories Chinese Academy of SciencesBeijing 100101China CAS Key.Laboratory.of FAST National Astronomical ObservatoriesChinese Academy of SciencesBeijing 100101China School of Astronom.0}and Space Sciences University of Chinese Academy of SciencesBeijing 100049China

The triggering m.chanism.for radio lobes from.late-ty.e galax.es is not fully.*** sam.les are desired for a thorough investigation and *** utilizing the optical data from.the newly.released Dark energy.Spectroscopic Instrum.nt im.ging survey. and the radio sources from.the NRAO VLA Sky.Survey.and the Faint Im.ges of the Radio Sky.at Twenty.centim.ter,we identify.four Late-ty.e Galax.es with double Radio Lobes(La GRLs):J0217-3645,J0947+6220,J1412+3723 and J1736+*** previously.known La GRLs,we confirm.the correlation between radio power P_(1.4GHz)and stellar m.ss m.(*)of host ***(25/35)La GRLs belong to the blue cloud galax.es,while the newly.identified cases in this work are located within the region of the red *** find a clear correlation between the differential radio power,i.e.,the offset from.the P_(1.4GHz)-m.(*)relation,and the galaxy.color,indicating that bluer galax.es at a fixed m.(*)tend to host m.re powerful radio ***,the m.jority.31/36)of La GRLs are either located in a galaxy.group or display.ng a disturbed *** suggest that all of the galaxy.m.ss,color and surrounding environm.nt could play.im.ortant roles in triggering radio lobes in late-ty.e galax.es.

关键词： galax.es:active galax.es:jets galax.es:spiral radio continuum.galax.es