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An equivariant index theorem on R~n in the context of continuous fields of C*-algebras

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Science China Mathematics 2025年

作者： Baiying Ren Hang wang Zijing wang Research Center for Operator Algebras School of Mathematical SciencesEast China Normal University

We prove an equivariant index theorem on the Euclidean space using a continuous field of C*-algebras. This generalizes the work of Elliott et al.（1996）, which is a special case of the algebraic index theorem by nest and Tsygan （1995）. Using our formula, we see that the equivariant index of the Bott-Dirac operator on R2ncan be explicitly calculated.

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Antithetical impacts of deleterious LRP1B mutations in non-squamous and squamous nSCLCs on predicting benefits from immune checkpoint inhibitor alone or with chemotherapy over chemotherapy alone: retrospective analyses of the POPLAR/OAK and CHOICE-01 trial

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Science China Life Sciences 2025年第1期68卷 249-262页

作者： Jinliang wang Wenyong Zhou Yu xu Jianchun Duan Qiaoxia Zhou Guoqiang wang Leo Li Chunwei xu Wenxian wang Shangli Cai Zhijie wang Jie wang Department of Oncology The Fifth Medical Center of Chinese PLA General Hospital Department of Thoracic Surgery Shanghai Chest HospitalSchool of MedicineShanghai Jiao Tong University Burning Rock Biotech CAMS Key Laboratory of Translational Research on Lung Cancer State Key Laboratory of Molecular OncologyDepartment of Medical OncologyNational Cancer Center/National Clinical Research Center for ancer/Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical College Institute of Basic Medicine and Cancer (IBMC) Chinese Academy of Sciences Department of Clinical Trial The Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital)

In non-small cell lung cancers,the non-squamous and squamous subtypes（nsqnSCLC and sqnSCLC） exhibit disparities in pathophysiology,tumor immunology,and potential genomic correlates affecting responses to immune checkpoint inhibitor（ICI）-based *** our inhouse training cohort（n=85）,the presence of the LRP1B deleterious mutation（LRP1B-del） was associated with longer and shorter progression-free survival（PFS） on ICIs alone in nsqnSCLCs and sqnSCLCs,respectively(Pinteraction=0.008).These results were validated using a larger public ICI cohort(n=208,Pinteractionx immunofluorescence staining revealed an association between LRP1B-del and increased and decreased numbers of tumor-infiltrating CD8+T cells in nsqnSCLCs（P=0.040） and sqnSCLCs（P=0.014）,*** the POPLAR/OAK cohort,nsqnSCLCs with LRP1B-del demonstrated improved PFS benefits from atezolizumab over docetaxel(hazard ratio（HR）=0.70,P=0.046),whereas this benefit was negligible in those without LRP1B-del（HR=1.05,P=0.64）.Conversely,sqnSCLCs without LRP1B-del benefited more from atezolizumab（HR=0.60,P=0.002） than those with LRP1B-del（HR=1.30,P=0.31）.Consistent results were observed in the in-house CHOICE-01 cohort,in which nsqnSCLCs with LRP1B-del and sqnSCLCs without LRP1B-del benefited more from toripalimab plus chemotherapy than from chemotherapy alone(Pinteraction=0.008).This multi-cohort study delineates the antithetical impacts of LRP1B-del in nsqnSCLCs and sqnSCLCs on predicting the benefits from ICI alone or with chemotherapy over chemotherapy *** findings highlight the distinct clinical utility of LRP1B-del in guiding treatment choices for nsqnSCLCs and sqnSCLCs,emphasizing the necessity for a detailed analysis based on pathological subtypes when investigating biomarkers for cancer therapeutics.

关键词： non-squamous nSCLC squamous nSCLC LRP1B deleterious mutations predictive biomarker immune checkpoint inhibitor

Integration of Electrical Properties and Polarization Loss Modulation on Atomic Fe–n‑RGO for Boosting Electromagnetic Wave Absorption

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nano-Micro Letters 2025年第2期17卷 517-532页

作者： Kaili Zhang Yuefeng Yan Zhen wang Guansheng Ma Dechang Jia xiaoxiao Huang Yu Zhou State Key Laboratory of Precision Welding&Joining of Materials and Structures Harbin Institute of TechnologyHarbin 150001People’s Republic of China School of Materials Science and Engineering Harbin Institute of TechnologyHarbin 150001People’s Republic of China MIIT Key Laboratory of Advanced Structural‑Functional Integration Materials&Green Manufacturing Technology Harbin Institute of TechnologyHarbin 150001People’s Republic of China

Developing effective strategies to regulate graphene’s conduction loss and polarization has become a key to expanding its application in the electromagnetic wave absorption(EMWA)*** on the unique energy band structure of graphene,regulating its bandgap and electrical properties by introducing heteroatoms is considered a feasible ***,metal-nitrogen doping reduced graphene oxide(M–n-RGO)was prepared by embedding a series of single metal atoms M–n_(4) sites(M=Mn,Fe,Co,ni,Cu,Zn,nb,Cd,and Sn)in RGO using an n-coordination atom-assisted *** composites had adjustable conductivity and polarization to optimize dielectric loss and impedance matching for efficient EMWA *** results showed that the minimum reflection loss(RL_(min))of Fe–n-RGO reaches−74.05 dB(2.0 mm)and the maximum effective absorption bandwidth(EAB_(max))is 7.05 GHz(1.89 mm)even with a low filler loading of only 1 wt%.Combined with x-ray absorption spectra(xAFS),atomic force microscopy,and density functional theory calculation analysis,the Fe–n_(4) can be used as the polarization center to increase dipole polarization,interface polarization and defect-induced polarization due to d-p orbital hybridization and structural ***,electron migration within the Fe further leads to conduction loss,thereby synergistically promoting energy *** study demonstrates the effectiveness of metal-nitrogen doping in regulating the graphene′s dielectric properties,which provides an important basis for further investigation of the loss mechanism.

关键词： Electromagnetic wave absorption Fe-n-RGO Dipole polarization Conduction loss Impedance matching

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Synergistically S/n self-doped biochar as a green bifunctional cathode catalyst in electrochemical degradation of organic pollutant

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Green Energy & Environment 2025年第1期10卷 214-230页

作者： xuechun wang Huizhong Wu Jiana Jing Ge Song xuyang Zhang Minghua Zhou Raf Dewil Key Laboratory of Pollution Process and Environmental Criteria Ministry of EducationCollege of Environmental Science and EngineeringNankai UniversityTianjin300350China Tianjin Key Laboratory of Environmental Technology for Complex Trans-Media Pollution Nankai UniversityTianjin300350China Tianjin Advanced Water Treatment Technology International Joint Research Center College of Environmental Science and EngineeringNankai UniversityTianjin300350China Department of Chemical Engineering KU LeuvenJ.De Nayerlaan 5Sint-Katelijne-Waver B2860Belgium

Biomass-derived heteroatom self-doped cathode catalysts has attracted considerable interest for electrochemical advanced oxidation processes(EAOPs)due to its high performance and sustainable ***,we illustrated the morphological fates of waste leaf-derived graphitic carbon(WLGC)produced from waste ginkgo leaves via pyrolysis temperature regulation and used as bifunctional cathode catalyst for simultaneous H_(2)O_(2) electrochemical generation and organic pollutant degradation,discovering S/n-self-doping shown to facilitate a synergistic effect on reactive oxygen species(ROS)*** the optimum temperature of 800℃,the WLGC exhibited a H_(2)O_(2) selectivity of 94.2%and tetracycline removal of 99.3%within 60 *** functional theory calculations and in-situ Fourier transformed infrared spectroscopy verified that graphitic n was the critical site for H_(2)O_(2) *** pyridinic n and thiophene S were the main active sites responsible for_OH generation,n vacancies were the active sites to produce ^(1)O_(2) from *** performance of the novel cathode for tetracycline degradation remains well under a wide pH range(3–11),maintaining excellent stability in 10 *** is also industrially applicable,achieving satisfactory performance treating in real water *** system facilitates both radical and non-radical degradation,offering valuable advances in the preparation of cost-effective and sustainable electrocatalysts and hold strong potentials in metal-free EAOPs for organic pollutant degradation.

关键词： Biochar S and n self-doping H_(2)O_(2)production In-situ FTIR Metal-free electrochemical advanced oxidation processes

体素内不相干运动(IVIM)扩散加权成像应用于前列腺癌Gleason分级的直方图分析

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国际医学放射学杂志 2015年第3期 299-299页

作者： Y.D.Zhang Q.wang C.J.Wu x.n.wang J.Zhang H.Liu 楼清清 Department of Radiology the First Affiliated Hospital with Nanjing Medical University

目的评价体素内不相干运动(IVIM)用于前列腺癌(PCa)Gleason分级的直方图分析。方法 48例经病理证实的具有临床意义的PCa(肿瘤>0.5 cm)行术前DWI(b值为0~

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Small modifications of endo-functionalized cavities lead to large changes in molecular interaction in water

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Science China Chemistry 2025年第1期68卷 369-376页

作者： Song-Meng wang Hao nian Yan-Fang wang Li-Shuo Zheng Yu-Tao Zheng Yi-Wei Dong Liping Huang xiaoping wang Wei Jiang Liu-Pan Yang Department of Chemistry Southern University of Science and Technology School of Chemistry and Pharmaceutical Sciences State Key Laboratory for Chemistry and Molecular Engineering of Medicinal ResourcesGuangxi Normal University School of Pharmaceutical Science Hengyang Medical School University of South China

Studying molecular recognition in aqueous environments is crucial for understanding biological processes. Herein, we present a series of n-doped endo-functionalized anthracene-based cavities by introducing inward-directed pyridine units. The subtle modifications can significantly affect the binding properties of these receptors, which is similar to the mutations in biological systems. Combining theoretical calculations and molecular recognition experiments demonstrated that these “mutations” have an impact on the hydrophobicity and charge distribution of the hosts, consequently significantly influencing molecular *** is crucial for understanding the intricate mechanisms of molecular-level interactions in biological receptors.

关键词： host-guest interaction hydrophobic effect endo-functionalized cavity mutation pyridine

Thickness and sp3 bond modulation of（Ti/tetrahedral amorphous carbon）_n multilayer coatings

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Tungsten 2025年第1期7卷 152-160页

作者： Zhi-Jun xie Jia-Lin Li Ling Gong xiang-Li Zhong Hong-Jia Song Jin-Bin wang national-Provincial Laboratory of Special Function Thin Film Materials School of Materials Science and Engineering Xiangtan University

The durability of wear-resistant tetrahedral amorphous carbon（ta-C） coatings is intimately linked to their thickness and the concentration of *** enhance the lifespan of the coatings,we have prepared a multilayer coating consisting of alternating layers of Ti and ta-C,denoted as（Ti/ta-C）_n,using arc ion plating.A multi-layer structure in conjunction with stage cooling is employed to enhance the thickness and promote *** results indicate that the ID/IGvalue,representing the ratio of the intensity of the D peak to that of the G peak in Raman spectroscopy,decreases from 0.85 when no stage cooling is applied to 0.35 when stage cooling is employed,suggesting an enhancement in the fraction of sp3bonds within the *** obtained（Ti/ta-C）_n multilayer coating without peeling off has a maximum thickness of 1.14 μm,which is almost double that of the ta-C coating single layer *** the same time,the coating has a low coefficient of friction,down to 0.069,and maintains excellent friction properties with a wear rate of 3.4×10-6mm3·n-1·*** results conclusively show that the preparation technology can enhance both thickness and sp3bonding in ta-C coatings,significantly expanding their utility across tools,molds,and precision engineering components.

关键词： Arc ion plating Multilayer structure sp3 bond Ta-C coating Wear resistance

Construction of hybrid Z-scheme graphitic C_(3)n_(4)/reduced TiO_(2) microsphere with visible-light-driven photocatalytic activity

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Journal of Materiomics 2018年第3期4卷 238-246页

作者： C.Zhou n.F.Ye x.H.Yan J.J.wang J.M.Pan D.F.wang Q.wang J.x.Zu x.n.Cheng School of Materials Science and Engineering Jiangsu UniversityZhenjiang212013JiangsuChina Institute for Advanced Materials Jiangsu UniversityZhenjiang212013JiangsuChina Institute of Green Materials and Metallurgy Jiangsu UniversityZhenjiang 212013JiangsuChina

A novel Z-scheme graphitic C_(3)n_(4)/reduced TiO_(2)microsphere(g-C_(3)n_(4)/r-TiO_(2))has been successfully synthesized by a solvothermal *** as-prepared samples with different contents of g-C_(3)n_(4)were characterized by x-ray diffraction,electron paramagnetic resonance,scanning electron microscope,UV *** reflectance and photoluminescence *** r-TiO_(2)microspheres are aggregated on the surface of g-C_(3)n_(4)sheets in the as-prepared g-C_(3)n_(4)/r-TiO_(2)*** g-C_(3)n_(4)/r-TiO_(2)catalysts show enhanced photocatalytic activity for the degradation of rhodamine B under visible light *** could be attributed to these influences of oxygen vacancy(changing the band gap of TiO_(2)),the large specific surface area(providing much more active sites for photocatalytic reaction),and the synergetic effect between g-C_(3)n_(4)and r-TiO_(2)(promoting the separation for photoinduced electron-hole pairs).Moreover,the Z-scheme carriers transfer mechanism in the photocatalytic process has been discussed through trapping experiments of active *** work demonstrates the strategies of the construction of Z-scheme carriers transfer system,the introduction of oxygen vacancy and structure designing are beneficial to design materials toward solar energy conversion like contaminant degradation.

关键词： TiO_(2) C_(3)n_(4) Oxygen vacancy Z-scheme heterojunction Photocatalytic performance

MR影像组学机器学习方法有助于提高PI-RADSv2在临床相关前列腺癌的诊断效能

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国际医学放射学杂志 2017年第6期 740-740页

作者： J.wang C.J.Wu M.L.Bao J.Zhang x.n.wang Y.D.Zhang 崔艳芬 Department of Radiology the First Affiliated Hospital with Nanjing Medical University

摘要目的探究MRI影像组学的机器学习方法是否有助于提高前列腺成像报告和数据系统(PI-RADS v2)在临床相关前列腺癌(PCa)的诊断效能。方法本研究经机构伦理委

关键词：诊断效能 PI-RADSv2 MR 机器学习方法前列腺癌