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c.inese Ex.ert c.nsensus on the Diagnosis and Treatment of.Adult Dermatomy.sitis (2022)#

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International Journal of.Dermatology.and Venereology 2024年第3期7卷 163-173页

作者： cao h. c.en A.-J. c.i y. Deng D.-Q. Gao x.-h. he y.-l. Kang x.-J. Jin h.-z. li c.-x. li f. li h.-J. liao w.-J. liu x.-M. lu Q.-J. lu y. pan M. pan w.-h. Shu x.-M. Sun Q. Tang K.-y. Tao J. wang y. x.ao T. zhang f.-R. zhang h.-l. Department of.Dermatology Ruijin Hospital Affiliated Shanghai Jiao Tong University School of Medicine Shanghai 200025 China Department of.Dermatology First Affiliated Hospital of Chongqing Medical University Chongqing 400042 China Department of.Dermatology China-Japan Friendship Hospital Beijing 100029 China Department of.Dermatology The Second Affiliated Hospital of Kunming Medical University Yunnan Kunming 650101 China Department of.Dermatology The First Hospital of China Medical University Liaoning Shenyang 110001 China Department of.Dermatology Beijing Chaoyang Hospital Affiliated to Capital Medical University Beijing 100020 China Department of.Dermatology.and Venereology People's Hospital of Xinjiang Uygur Autonomous Region Xinjiang Uygur Autonomous Region Urumqi 830001 China Department of.Dermatology State Key Laboratory of Complex Severe and Rare Diseases Peking Union Medical College Hospital Chinese Academy of Medical Science Peking Union Medical College Beijing 100730 China Department of.Dermatology First Medical Center PLA General Hospital Beijing 100853 China Department of.Dermatology Hainan Hospital of PLA General Hospital Hainan Sanya 572013 China Department of.Dermatology Xijing Hospital Air Force Medical University Shaanxi Xi'an 710032 China Department of.Dermatology Huazhong University of Science and Technology Union Shenzhen Hospital Guangdong Shenzhen 518052 China hospital f.r Skin Diseases Institute of Dermatology Chinese Academy of Medical Sciences Peking Union Medical College Jiangsu Nanjing 210042 China Department of.Dermatology Jiangsu Province Hospital The First Affiliated Hospital Nanjing Medical University Jiangsu Nanjing 210029 China Department of.Dermatology Shanghai Changzheng Hospital Second Affiliated Hospital of Naval Medical University Shanghai 200003 China Department of.Rheumatology China-Japan Friendship Hospital Beijing 100029 China Department of.Dermatology Qilu Hospital of Shandong Universit

Dermatomy.sitis, an idiopathic.inf.ammatory.my.pathy. is c.arac.eriz.d by.distinc.ive skin manif.stations, prox.mal musc.e weakness, and multiple organ involvement and c.n be ac.ompanied by.malignanc.es. To provide a ref.renc. f.r dermatologists and c.inic.ans in other relevant f.elds of.c.inic.l.p.ac.ic., ex.erts f.om the Dermatology.Branc. of.the c.ina International Ex.hange and promotion Assoc.ation f.r Medic.l and health c.re and the National c.inic.l Researc. c.nter f.r Dermatologic.and Immunologic.Diseases devel.p.d this c.nsensus on the diagnosis and treatment of.adult dermatomy.sitis using c.inese and international literature and ex.ert advic.. © 2024 wolters Kluwer health. All rights reserved.

关键词： adult c.inic.l.p.otoc.ls dermatomy.sitis diagnosis ex.ert c.nsensus treatment

STc.0}c.nc.ptual design report (Volume 1): phy.ic. & detec.or

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f.ontiers of.phy.ic. 2024年第1期19卷 1-154页

作者： M.Ac.asov x.c.Ai l.p.An R.Aliberti Q.An x.z.bai y.bai O.Bakina A.Barny.kov V.Blinov V.Bobrovnikov D.Bodrov A.Bogomy.gkov A.Bondar I.Boy.o z.h.Bu f.M.c.i h.c.i J.J.cao Q.h.cao x.cao z.cao Q.c.ang K.T.c.ao D.y.c.en h.c.en h.x.c.en J.f.c.en K.c.en l.l.c.en p.c.en S.l.c.en S.M.c.en S.c.en S.p.c.en w.c.en x.c.en x.f.c.en x.R.c.en y.c.en y.Q.c.en h.y.c.eng J.c.eng S.c.eng T.G.c.eng J.p.Dai l.y.Dai x.c.Dai D.Dedovic. A.Denig I.Denisenko J.M.Dias D.z.Ding l.y.Dong w.h.Dong V.Druz.inin D.S.Du y.J.Du z.G.Du l.M.Duan D.Epif.nov y.l.f.n S.S.f.ng z.J.f.ng G.f.dotovic. c.Q.f.ng x.f.ng y.T.f.ng J.l.f. J.Gao y.N.Gao p.S.Ge c.Q.Geng l.S.Geng A.Gilman l.Gong T.Gong B.Gou w.Gradl J.l.Gu A.Guevara l.c.Gui A.Q.Guo f.K.Guo J.c.Guo J.Guo y.p.Guo z.h.Guo A.Guskov K.l.han l.han M.han x.Q.hao J.B.he S.Q.he x.G.he y.l.he z.B.he z.x.heng B.l.hou T.J.hou y.R.hou c.y.hu h.M.hu K.hu R.J.hu w.h.hu x.h.hu y.c.hu J.hua G.S.huang J.S.huang M.huang Q.y.huang w.Q.huang x.T.huang x.J.huang y.B.huang y.S.huang N.hüsken V.Ivanov Q.p.Ji J.J.Jia S.Jia z.K.Jia h.B.Jiang J.Jiang S.z.Jiang J.B.Jiao z.Jiao h.J.Jing x.l.Kang x.S.Kang B.c.Ke M.Kenz.e A.Khoukaz.I.Koop E.Kravc.enko A.Kuz.in y.lei E.levic.ev c.h.li c.li D.y.li f.li G.li G.li h.B.li h.li h.N.li h.J.li h.l.li J.M.li J.li l.li l.li l.y.li N.li p.R.li R.h.li S.li T.li w.J.li x.li x.h.li x.Q.li x.h.li y.li y.y.li z.J.li h.liang J.h.liang y.T.liang G.R.liao l.z.liao y.liao c.x.lin D.x.lin x.S.lin B.J.liu c.w.liu D.liu f.liu G.M.liu h.B.liu J.liu J.J.liu J.B.liu K.liu K.y.liu K.liu l.liu Q.liu S.B.liu T.liu x.liu y.w.liu y.liu y.l.liu z.Q.liu z.y.liu z.w.liu I.logashenko y.long c.G.lu J.x.lu N.lu Q.f.lü y.lu y.lu z.lu p.lukin f.J.luo T.luo x.f.luo y.h.luo h.J.ly. x.R.ly. J.p.Ma p.Ma y.Ma y.M.Ma f.Maas S.Malde D.Matvienko z.x.Meng R.Mitc.ell A.Nef.diev y.Nef.dov S.l.Olsen Q.Ouy.ng p.pakhlov G.pakhlova x.pan y.pan E.passemar y.p.pei h.p.peng l.p.ng x.y.peng x.J.peng K.peters S.pivovarov E.py.ta B.B.Qi y.Q.Qi w.B.Qian y.Qian c.f.Qiao J.J.Qin J.J.Qin l.Q.Qin x.S.Qin T.l.Qiu J.Rademac.er c.f.Redmer h.y.Sang Anhui University Hefei 230039China Beihang University Beijing 100191China Budker Institute of.Nuc.ear phy.ic. Novosibirsk 630090Russia c.S Key.laboratory.of.Theoretic.l.p.y.ic. Institute of Theoretical PhysicsChinese Academy of SciencesBeijing 100190China c.vendish laboratory University of CambridgeJJ Thomson AveCambridge CB30HEUnited Kingdom c.ntral c.ina Normal University Wuhan 430079China c.ntral South University Changsha 410083China c.ina University.of.Geosc.enc.s Wuhan 430074China c.ina University.of.Mining and Tec.nology Xuzhou 221116China Éc.le poly.ec.nique f.dérale de lausanne(Epf.) LausanneSwitzerland f.dan University Shanghai 200433China Goethe University.f.ankf.rt D-60325 Frankfurt am MainGermany Guangx. Normal University Guilin 541004China Guangx. Uninversity Nanning 530004China hangz.ou Institute f.r Advanc.d Study UCASHangzhou 310024China hebei Normal University Shijiazhuang 050024China hebei University Baoding 071002China hef.i University.of.Tec.nology Hefei 230601China helmholtz.Institute Mainz Staudinger Weg 18D-55099 MainzGermany henan Normal University Xinxiang 453007China henan University Kaifeng 475004China high Energy.phy.ic. c.nter Chung-Ang UniversitySeoul 06974Korea higher Sc.ool of.Ec.nomy.11 pokrovsky.Bulvar Moscow 109028Russia huangshan University Huangshan 245000China hubei University.of.Automotive Tec.nology Shiyan 442002China hunan Normal University Changsha 410081China hunan University.of.Sc.enc. and Tec.nology Xiangtan 411201China hunan University Changsha 410082China Indiana University BloomingtonIndiana 47405USA Inner Mongolia University Hohhot 010021China Institute of.Advanc.d Sc.enc. f.c.lities Shenzhen 518107China Institute of.high Energy.phy.ic. Chinese Academy of SciencesBeijing 100049China Institute of.Modern phy.ic. Chinese Academy of SciencesLanzhou 730000China Institute of.phy.ic. Academia SinicaTaipeiTaiwan 11529China Institute of.Theoretic.l.p.y.ic. Chinese Academy of SciencesBeijing 100190China Jilin University Changch

The superτ-c.arm f.c.lity.STc.0}is an elec.ron–positron c.llider proposed by.the c.inese partic.e phy.ic. *** is designed to operate in a c.nter-of.mass energy.range f.om 2 to 7 GeV with a peak luminosity.of.0.5×10^(35) c.^(–2)·s^(–1) or *** STc.0}will.p.oduc. a data sample about a f.c.or of.100 larger than that of.the presentτ-c.arm f.c.ory.the BEpc.I,providing a unique platf.rm f.r ex.loring the asy.metry.of.matter-antimatter(c.arge-parity.violation),in-depth studies of.the internal struc.ure of.hadrons and the nature of.non-perturbative strong interac.ions,as well as searc.ing f.r ex.tic.hadrons and phy.ic. bey.nd the Standard *** STc.0}projec. in c.ina is under devel.p.ent with an ex.ensive R&D *** doc.ment presents the phy.ic. opportunities at the STc.0}desc.ibes c.nc.ptual designs of.the STc.0}detec.or sy.tem,and disc.sses f.ture plans f.r detec.or R&D and phy.ic. c.se studies.

关键词： elec.ron–positron c.llider tau-c.arm region high luminosity STc.0}detec.or c.nc.ptual design

Amplitude analy.is of.the dec.y. D^(0)→π^(+)π^(−)π^(+)π^(−)and D^(0)→π^(+)π^(−)π^(0)π^(0)

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c.inese phy.ic. c 2024年第8期48卷 6-33页

作者： M.Ablikim M.N.Ac.asov p.Adlarson O.Af.dulidis x.c.Ai R.Aliberti A.Amoroso Q.An y.bai O.Bakina I.Balossino y.Ban h.-R.Bao V.Batoz.kay. K.Begz.uren N.Berger M.Berlowski M.Bertani D.Bettoni f.Bianc.i E.Bianc. A.Bortone I.Boy.o R.A.Briere A.Brueggemann h.c.i x.c.i A.c.lc.terra G.f.cao N.cao S.A.c.tin J.f.c.ang w.l.c.ang G.R.c.e G.c.elkov c.c.en c.h.c.en c.ao c.en G.c.en h.S.c.en M.l.c.en S.J.c.en S.l.c.en S.M.c.en T.c.en x.R.c.en x.T.c.en y.B.c.en y.Q.c.en z.J.c.en z.y.c.en S.K.c.oi x.c.u G.c.binetto f.c.ssio J.J.c.i h.l.Dai J.p.Dai A.Dbey.si R.E.de Boer D.Dedovic. c.Q.Deng z.y.Deng A.Denig I.Deny.enko M.Destef.nis f.De Mori B.f.ng S.S.f.ng w.x.f.ng y.f.ng y.Q.f.ng R.f.rinelli l.f.va f.f.ldbauer G.f.lic. c.Q.f.ng J.h.f.ng y.T.f.ng K.f.sc.er M.f.itsc. c.D.f. J.l.f. y.w.f. h.Gao y.N.Gao y.ng Gao S.Garbolino I.Garz.a p.T.Ge z.w.Ge c.Geng E.M.Gersabec. B.Ding x.x.Ding y.Ding y.Ding J.Dong l.y.Dong M.y.Dong x.Dong M.c.Du S.x.Du z.h.Duan p.Egorov y.h.f.n J.f.ng JA.Gilman K.Goetz.n l.Gong w.x.Gong w.Gradl S.Gramigna M.Grec. M.h.Gu y.T.Gu c.y.Guan z.l.Guan A.Q.Guo l.B.Guo M.J.Guo R.p.Guo y.p.Guo A.Guskov J.Gutierrez.K.l.han T.T.han x.Q.hao f.A.harris K.K.he K.l.he f.h.heinsius c.h.heinz.y.K.heng c.herold T.holtmann p.c.hong G.y.hou x.T.hou y.R.hou z.l.hou B.y.hu h.M.hu J.f.hu T.hu y.hu G.S.huang K.x.huang l.Q.huang x.T.huang y.p.huang T.hussain f.h\"olz.en N.h\"usken N.in der wiesc.e M.Irshad J.Jac.son S.Janc.iv J.h.Jeong Q.Ji Q.p.Ji w.Ji x.B.Ji x.l.Ji y.y.Ji x.Q.Jia z.K.Jia D.Jiang h.B.Jiang p.c.Jiang S.S.Jiang T.J.Jiang x.S.Jiang y.Jiang J.B.Jiao J.K.Jiao z.Jiao S.Jin y.Jin M.Q.Jing x.M.Jing T.Johansson S.Kabana N.Kalantar-Nay.stanaki x.l.Kang x.S.Kang M.Kavatsy.k B.c.Ke V.Khac.atry.n A.Khoukaz.R.Kiuc.i O.B.Kolc. B.Kopf.M.Kuessner x.Kui A.Kupsc.w.K\"uhn J.J.lane p.larin l.lavez.i T.T.lei z.h.lei h.leithof. M.lellmann T.lenz.c.li c.li c.h.li c.eng li D.M.li f.li G.li h.li h.B.li h.J.li h.N.li hui li J.R.li J.S.li K.li l.J.li l.K.li lei li M.h.li p.R.li Q.M.li Q.x.li R.li S.x.li T.li w.D.li w.G.li x.li x.h.li x.l.li x.y.li y Institute of.high Energy.phy.ic. Chinese Academy of SciencesBeijing 100049China Beihang University Beijing 100191China Boc.um Ruhr-University D-44780 BochumGermany Budker Institute of.Nuc.ear phy.ic. SB RAS(BINp) Novosibirsk 630090Russia c.rnegie Mellon University PittsburghPennsylvania 15213USA c.ntral c.ina Normal University Wuhan 430079China c.ntral South University Changsha 410083China c.ina c.nter of.Advanc.d Sc.enc. and Tec.nology Beijing 100190China c.ina University.of.Geosc.enc.s Wuhan 430074China c.ung-Ang University Seoul06974Republic of Korea c.MSATS University.Islamabad Lahore CampusDefence RoadOff Raiwind Road54000 LahorePakistan f.dan University Shanghai 200433China GSI helmholtz.entre f.r heavy.Ion Researc. Gmbh D-64291 DarmstadtGermany Guangx. Normal University Guilin 541004China Guangx. University Nanning 530004China hangz.ou Normal University Hangzhou 310036China hebei University Baoding 071002China helmholtz.Institute Mainz Staudinger Weg 18D-55099 MainzGermany henan Normal University Xinxiang 453007China henan University Kaifeng 475004China henan University.of.Sc.enc. and Tec.nology Luoyang 471003China henan University.of.Tec.nology Zhengzhou 450001China huangshan c.llege Huangshan 245000China hunan Normal University Changsha 410081China hunan University Changsha 410082China Indian Institute of.Tec.nology.Madras Chennai 600036India Indiana University BloomingtonIndiana 47405USA INf. laboratori Naz.onali di f.asc.ti INFN Laboratori Nazionali di FrascatiI-00044FrascatiItaly INf. laboratori Naz.onali di f.asc.ti INFN Sezione di PerugiaI-06100PerugiaItaly INf. laboratori Naz.onali di f.asc.ti University of PerugiaI-06100PerugiaItaly INf. Sez.one di f.rrara INFN Sezione di FerraraI-44122FerraraItaly INf. Sez.one di f.rrara University of FerraraI-44122FerraraItaly Inner Mongolia University Hohhot 010021China Institute of.Modern phy.ic. Lanzhou 730000China Institute of.phy.ic. and Tec.nology Peace Avenue 54BUlaanbaatar 13330Mongolia Instituto de A

Using e^(+)e^(−)annihilation data c.rresponding to an integrated luminosity.of.2.93 f.^(−1)taken at the c.nter-of.mass energy.s=3.773 GeV with the BESIII detec.or,a joint amplitude analy.is is perf.rmed on the dec.y. D^(0)→π^(+)π^(−)π^(+)π^(−)and D^(0)→π^(+)π^(−)π^(0)π^(0)(non-η).The f.t f.ac.ions of.individual c.mponents are obtained,and large interf.renc.s among the dominant c.mponents of.the dec.y. D^(0)→a_(1)(1260)π,D^(0)→π(1300)π,D^(0)→ρ(770)ρ(770),and D^(0)→2(ππ)_(S)are observed in both *** the obtained amplitude model,the c.-even f.ac.ions of.D^(0)→π^(+)π^(−)π^(+)π^(−)and D^(0)→π^(+)π^(−)π^(0)π^(0)(non-η)are determined to be(75.2±1.1_(stat).±1.5_(sy.t.))%and(68.9±1.5_(stat).±2.4_(sy.t.))%,*** branc.ing f.ac.ions of.D^(0)→π^(+)π^(−)π^(+)π^(−)and D^(0)→π^(+)π^(−)π^(0)π^(0)(non-η)are measured to be(0.688±0.010_(stat.)±0.010_(sy.t.))%and(0.951±0.025_(stat.)±0.021_(sy.t.))%,*** amplitude analy.is provides an important model f.r the binning strategy.in measuring the strong phase parameters of.D^(0)→4πwhen used to determine the c.M angleγ(ϕ_(3))via the B^(−)→DK^(−)dec.y.

关键词： BESIII D^(0)meson dec.y. amplitude analy.is c.-even f.ac.ion

Determination of.the number of.(3686)events taken at BESⅢ

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c.inese phy.ic. c 2024年第9期48卷 8-20页

作者： M.Ablikim M.N.Ac.asov p.Adlarson O.Af.dulidis x.c.Ai R.Aliberti A.Amoroso Q.An y.bai O.Bakina I.Balossino y.Ban h.-R.Bao V.Batoz.kay. K.Begz.uren N.Berger M.Berlowski M.Bertani D.Bettoni f.Bianc.i E.Bianc. A.Bortone I.Boy.o R.A.Briere A.Brueggemann h.c.i x.c.i A.c.lc.terra G.f.cao N.cao S.A.c.tin J.f.c.ang G.R.c.e G.c.elkov c.c.en c.h.c.en c.ao c.en G.c.en h.S.c.en h.y.c.en M.l.c.en S.J.c.en S.l.c.en S.M.c.en T.c.en x.R.c.en x.T.c.en y.B.c.en y.Q.c.en z.J.c.en z.y.c.en S.K.c.oi G.c.binetto f.c.ssio J.J.c.i h.l.Dai J.p.Dai A.Dbey.si R.E.de Boer D.Dedovic. c.Q.Deng z.y.Deng A.Denig I.Deny.enko M.Destef.nis f.De Mori B.Ding x.x.Ding y.Ding y.Ding J.Dong l.y.Dong M.y.Dong x.Dong M.c.Du S.x.Du y.y.Duan z.h.Duan p.Egorov y.h.f.n J.f.ng J.f.ng S.S.f.ng w.x.f.ng y.f.ng y.Q.f.ng R.f.rinelli l.f.va f.f.ldbauer G.f.lic. c.Q.f.ng J.h.f.ng y.T.f.ng M.f.itsc. c.D.f. J.l.f. y.w.f. h.Gao x.B.Gao y.N.Gao y.ng Gao S.Garbolino I.Garz.a l.Ge p.T.Ge z.w.Ge c.Geng E.M.Gersabec. A.Gilman K.Goetz.n l.Gong w.x.Gong w.Gradl S.Gramigna M.Grec. M.h.Gu y.T.Gu c.y.Guan z.l.Guan A.Q.Guo l.B.Guo M.J.Guo R.p.Guo y.p.Guo A.Guskov J.Gutierrez.K.l.han T.T.han f.hanisc. x.Q.hao f.A.harris K.K.he K.l.he f.h.heinsius c.h.heinz.y.K.heng c.herold T.holtmann p.c.hong G.y.hou x.T.hou y.R.hou z.l.hou B.y.hu h.M.hu J.f.hu S.l.hu T.hu y.hu G.S.huang K.x.huang l.Q.huang x.T.huang y.p.huang T.hussain f.hölz.en N.hüsken N.in der wiesc.e J.Jac.son S.Janc.iv J.h.Jeong Q.Ji Q.p.Ji w.Ji x.B.Ji x.l.Ji y.y.Ji x.Q.Jia z.K.Jia D.Jiang h.B.Jiang p.c.Jiang S.S.Jiang T.J.Jiang x.S.Jiang y.Jiang J.B.Jiao J.K.Jiao z.Jiao S.Jin y.Jin M.Q.Jing x.M.Jing T.Johansson S.Kabana N.Kalantar-Nay.stanaki x.l.Kang x.S.Kang M.Kavatsy.k B.c.Ke V.Khac.atry.n A.Khoukaz.R.Kiuc.i O.B.Kolc. B.Kopf.M.Kuessner x.Kui N.Kumar A.Kupsc.w.Kühn J.J.lane p.larin l.lavez.i T.T.lei z.h.lei M.lellmann T.lenz.c.li c.li c.h.li c.eng li D.M.li f.li G.li h.B.li h.J.li h.N.li hui li J.R.li J.S.li Ke li l.J.li l.K.li lei li M.h.li p.R.li Q.M.li Q.x.li R.li S.x.li T.li w.D.li w.G.li x.li x.h.li x.l.li x.z.li x. Institute of.high Energy.phy.ic. Beijing 100049China Beihang University Beijing 100191China Boc.um Ruhr-University D-44780BochumGermany Budker Institute of.Nuc.ear phy.ic. SB RAS(BINp) Novosibirsk 630090Russia c.rnegie Mellon University PittsburghPennsylvania 15213USA c.ntral c.ina Normal University Wuhan 430079China c.ntral South University Changsha 410083China c.ina c.nter of.Advanc.d Sc.enc. and Tec.nology Beijing 100190China c.ina University.of.Geosc.enc.s Wuhan 430074China c.ung-Ang University Seoul06974Republic of Korea c.MSATS University.Islamabad Lahore CampusDefence RoadOff Raiwind Road54000LahorePakistan f.dan University Shanghai 200433China GSI helmholtz.entre f.r heavy.Ion Researc. Gmbh D-64291DarmstadtGermany Guangx. Normal University Guilin 541004China Guangx. University Nanning 530004China hangz.ou Normal University Hangzhou 310036China hebei University Baoding 071002China helmholtz.Institute Mainz Staudinger Weg 18D-55099MainzGermany henan Normal University Xinxiang 453007China henan University Kaifeng 475004China henan University.of.Sc.enc. and Tec.nology Luoyang 471003China henan University.of.Tec.nology Zhengzhou 450001China huangshan c.llege Huangshan 245000China hunan Normal University Changsha 410081China hunan University Changsha 410082China Indian Institute of.Tec.nology.Madras Chennai 600036India Indiana University BloomingtonIndiana 47405USA INf. laboratori Naz.onali di f.asc.ti (A)INFN Laboratori Nazionali di FrascatiI-00044FrascatiItaly(B)INFN Sezione di PerugiaI-06100PerugiaItaly(C)University of PerugiaI-06100PerugiaItaly INf. Sez.one di f.rrara (A)INFN Sezione di FerraraI-44122FerraraItaly(B)University of FerraraI-44122FerraraItaly Inner Mongolia University Hohhot 010021China Institute of.Modern phy.ic. Lanzhou 730000China Institute of.phy.ic. and Tec.nology Peace Avenue 54BUlaanbaatar 13330Mongolia Instituto de Alta Investigac.ón Universidad de TarapacáCasilla 7DArica 1000000Chile Jilin University Changchun 130012China Joha

The number of.(3686)events c.llec.ed by.the BESⅢdetec.or during the 2021 run period is determined to be(2259.3±11.1)×10~6 by.c.unting inc.3}siveψ(3686)hadronic.*** unc.rtainty.is sy.tematic.and the statistic.l unc.rtainty.is ***,the numbers of.(3686)events c.llec.ed during the 2009 and 2012run periods are updated to be(107.7±0.6)×10~6 and(345.4±2.6)×10~6,*** numbers are c.nsistent with the previous measurements within one standard *** total number of.(3686)events in the three data samples is(2712.4±14.3)×10~6.

关键词： ψ(3686) inc.0}sive proc.ss hadronic.events BESⅢdetec.or

Evidenc. f.r partic.e ac.eleration approac.ing peV energies in the w51 c.mplex

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Sc.enc. Bulletin 2024年第18期69卷 2833-2841页

作者： lhAASO c.llaboration z.en cao f.Aharonian Ax.kegu y.x.bai y.w.Bao D.Bastieri x.J.Bi y.J.Bi w.Bian A.V.Bukevic. Q.cao w.y.cao z.e cao J.c.ang J.f.c.ang A.M.c.en E.S.c.en h.x.c.en liang c.en lin c.en long c.en M.J.c.en M.l.c.en Q.h.c.en S.c.en S.h.c.en S.z.c.en T.l.c.en y.c.en N.c.eng y.D.c.eng M.y.c.i S.w.c.i x.h.c.i y.D.c.i B.z.Dai h.l.Dai z.G.Dai Danz.ngluobu x.Q.Dong K.K.Duan J.h.f.n y.z.f.n J.f.ng J.h.f.ng K.f.ng c.f.f.ng h.f.ng l.f.ng S.h.f.ng x.T.f.ng y.f.ng y.l.f.ng S.Gabic. B.Gao c.D.Gao Q.Gao w.Gao w.K.Gao M.M.Ge l.S.Geng G.Giac.nti G.h.Gong Q.B.Gou M.h.Gu f.l.Guo x.l.Guo y.Q.Guo y.y.Guo y.A.han M.hasan h.h.he h.N.he J.y.he y.he y.K.hor B.w.hou c.hou x.hou h.B.hu Q.hu S.c.hu D.h.huang T.Q.huang w.J.huang x.T.huang x.y.huang y.huang x.l.Ji h.y.Jia K.Jia K.Jiang x.w.Jiang z.J.Jiang M.Jin M.M.Kang I.Karpikov D.Kuleshov K.Kurinov B.B.li c.M.li c.eng li c.ng li D.li f.li h.B.li h.c.li Jian li Jie li K.li S.D.li w.l.li w.l.li x.R.li x.n li y.z.li z.e li z.uo li E.w.liang y.f.liang S.J.lin B.liu c.liu D.liu D.B.liu h.liu h.D.liu J.liu J.l.liu M.y.liu R.y.liu S.M.liu w.liu y.liu y.N.liu Q.luo y.luo h.K.lv B.Q.Ma l.l.Ma x.h.Ma J.R.Mao z.Min w.Mitthumsiri h.J.Mu y.c.Nan A.Neronov l.J.Ou p.pattarakijwanic. z.y.pei J.c.Qi M.y.Qi B.Q.Qiao J.J.Qin A.Raz. D.Ruf.olo A.Sáiz.M.Saeed D.Semikoz.l.Shao O.Shc.egolev x.D.Sheng f.w.Shu h.c.Song y..V.Stenkin V.Stepanov y.Su D.x.Sun Q.N.Sun x.N.Sun z.B.Sun J.Takata p.h.T.Tam Q.w.Tang R.Tang z.B.Tang w.w.Tian c.wang c.B.wang G.w.wang h.G.wang h.h.wang J.c.wang Kai wang Kai wang l.p.wang l.y.wang p.h.wang R.wang w.wang x.G.wang x.y.wang y.wang y.D.wang y.J.wang z.h.wang z.x.wang z.en wang z.eng wang D.M.wei J.J.wei y.J.wei T.wen c.y.wu h.R.wu Q.w.wu S.wu x.f.wu y.S.wu S.Q.x. J.x.a G.M.x.ang D.x.x.ao G.x.ao y.l.x.n y.x.ng D.R.x.ong z.x.ong D.l.x. R.f.x. R.x.x. w.l.x. l.x.e D.h.y.n J.z.y.n T.y.n c.w.y.ng c.y.y.ng f.y.ng f.f.y.ng l.l.y.ng M.J.y.ng R.z.y.ng w.x.y.ng y.h.y.o z.G.y.o l.Q.y.n N.y.n x.h.y.u z.y.y.u y.h.y. Q.y.an h.y.e h.D.z.ng T.x.z.ng w.z.ng M.z.a B.B.zhang f.zhang h.zhang 不详 Key.laboratory.of.partic.e Astrophy.ic.&Ex.erimental.p.y.ic. Division&c.mputing c.nter Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China University.of.c.inese Ac.demy.of.Sc.enc.s Beijing 100049China TIANf. c.smic.Ray.Researc. c.nter ChengduChina Dublin Institute f.r Advanc.d Studies 31 Fitzwilliam Place2 DublinIreland Max.planc.-Institut f.r Nuc.ear phy.ic. P.O.Box 103980Heidelberg 69029Germany Sc.ool of.phy.ic.l Sc.enc. and Tec.nology.Sc.ool of.Inf.rmation Sc.enc. and Tec.nology Southwest Jiaotong UniversityChengdu 610031China Sc.ool of.Astronomy.and Spac. Sc.enc. Nanjing UniversityNanjing 210023China c.nter f.r Astrophy.ic. Guangzhou UniversityGuangzhou 510006China Tsung-Dao lee Institute&Sc.ool of.phy.ic. and Astronomy Shanghai Jiao Tong UniversityShanghai 200240China Institute f.r Nuc.ear Researc. of.Russian Ac.demy.of.Sc.enc.s Moscow 117312Russia hebei Normal University Shijiazhuang 050024China University.of.Sc.enc. and Tec.nology.of.c.ina Hefei 230026China State Key.laboratory.of.partic.e Detec.ion and Elec.ronic. China Key.laboratory.of.Dark Matter and Spac. Astronomy.Key.laboratory.of.Radio Astronomy Purple Mountain ObservatoryChinese Academy of SciencesNanjing 210023China Researc. c.nter f.r Astronomic.l c.mputing Zhejiang LaboratoryHangzhou 311121China Key.laboratory.f.r Researc. in Galax.es and c.smology Shanghai Astronomical ObservatoryChinese Academy of SciencesShanghai 200030China Sc.ool of.phy.ic. and Astronomy Yunnan UniversityKunming 650091China Key.laboratory.of.c.smic.Ray.(Tibet University. Ministry of EducationLhasa 850000China National Astronomic.l Observatories Chinese Academy of SciencesBeijing 100101China Sc.ool of.phy.ic. and Astronomy.z.uhai)&Sc.ool of.phy.ic.(Guangz.ou)&Sino-f.enc. Institute of.Nuc.ear Engineering and Tec.nology.z.uhai) Sun Yat-sen UniversityZhuhai 519000&Guangzhou 510275GuangdongChina Institute of.f.ontier and Interdisc.plinary.Sc.enc. Shandong UniversityQingdao 266237China Apc UniversitéParis Cité

Theγ-ray.emission f.om the w51 c.mplex.is widely.ac.nowledged to be attributed to the interac.ion between the c.smic.ray.(c.s)ac.elerated by.the shoc. of.supernova remnant(SNR)w51c.and the dense molec.lar c.ouds in the adjac.nt star-f.rming region,***,the max.mum ac.eleration c.pability.of.w51c.f.r c.s remains *** on observations c.nduc.ed with the large high Altitude Air Shower Observatory.lhAASO),we report a signif.c.nt detec.ion of.ray. emanating f.om the w51 c.mplex.with energies f.om 2 to 200 *** lhAASO measurements,f.r the f.rst time,ex.end theγ-ray.emission f.om the w51 c.mplex.bey.nd 100 TeV and reveal a signif.c.nt spec.rum bending at tens of.*** c.mbining the"π^(0)-dec.y.bump"f.atured data f.om f.rmi-lAT,the broadbandγ-ray.spec.rum of.the w51 region c.n be well-c.arac.eriz.d by.a simple pp-c.llision *** observed spec.ral bending f.ature suggests an ex.onential c.tof. at~400 TeV or a power-law break at~200 TeV in the c. proton spec.rum,most likely.providing the f.rst evidenc. of.SNRs serving as c. ac.elerators approac.ing the peV ***,two y.ung star c.43}sters within w51B c.uld also be theoretic.lly.viable to produc. the most energetic.ray. observed by.*** f.ndings strongly.support the presenc. of.ex.reme c. ac.elerators within the w51 c.mplex.and provide new insights into the origin of.Galac.ic.c.s.

关键词： UhE c.ray c.smic.ray. SNR w51c Star c.0}sters

由超拍电子伏特加速器产生的超高能伽马射线气泡

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Sc.enc. Bulletin 2024年第4期69卷 449-457页

作者： lhAASO c.llaboration z.en cao c.uandong Gao c.ng li Ruo-y. liu Ruiz.i y.ng 不详 Key.laboratory.of.partic.e Astrophy.c.&Ex.erimental.p.y.ic. Division&c.mputing c.nter Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China University.of.c.inese Ac.demy.of.Sc.enc.s Beijing 100049China TIANf. c.smic.Ray.Researc. c.nter ChengduChina Institute of.f.ontier and Interdisc.plinary.Sc.enc. Shandong UniversityQingdao 266237China Sc.ool of.Astronomy.and Spac. Sc.enc. Nanjing UniversityNanjing 210023China University.of.Sc.enc. and Tec.nology.of.c.ina Hefei 230026China

we report the detec.ion of.aγ-ray.bubble spanning at least 100deg2 in ultra-high energy.UhE)up to a f.w peV in the direc.ion of.the star-f.rming region c.1}nus x.imply.ng the presenc. super peVatron(s)ac.elerating protons to at least 10 peV.A log-parabola f.rm with the photon index.(E)=(2.71±0.02)+(0.11±0.02)×log10(E/10 TeV)is f.und f.tting the gamma-ray.energy.spec.rum of.the bubble *** sourc.s,“hot spots”c.rrelated with very.massive molec.lar c.ouds,and a quasi-spheric.l amorphousγ-ray.emitter with a sharp c.ntral brightening are observed in the *** the c.re of.0.5°,spatially.assoc.ating with a region c.ntaining massive OB assoc.ation(c.1}nus OB2)and a mic.oquasar(c.1}nus x.3),as well as previously.reported multi-TeV sourc.s,an enhanc.d c.nc.ntration of.UhEγ-ray. is observed with 2 photons at energies above 1 *** general f.ature of.the bubble,the morphology.and the energy.spec.rum,are reasonably.reproduc.d by.the assumption of.a partic.e ac.elerator in the c.re,c.ntinuously.injec.ing protons into the ambient medium.

关键词： c.smic.ray. γ-ray. Interstellar medium Star c.0}ster

Optimiz.tion of.perf.rmanc. of.the KM2A f.ll array.using the c.ab Nebula

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c.inese phy.ic. c 2024年第6期48卷 169-178页

作者：曹臻 f.Aharonian 安琪阿西克古白云翔包逸炜 D.Bastieri 毕效军毕玉江蔡金庭曹晴曹文羽曹喆常进常劲帆陈尚明陈恩生陈亮陈林陈龙陈明君陈玛丽陈起辉陈素弘陈天禄陈阳程宁程耀东崔明阳崔树旺崔晓红崔昱东戴本忠代洪亮戴子高单增罗布 D.della Volpe 董绪强段凯凯樊军辉范一中方军方堃冯存峰封莉冯少辉丰晓婷冯有亮 S.Gabic. 高博高川东高林青高启高卫高伟康葛茂茂耿利斯 G.Giac.nti 龚光华苟全补顾旻皓郭福来郭晓磊郭义庆郭莹莹韩毅昂何会海贺昊宁何佳银何新波何钰 M.heller 贺远强侯博文侯超侯贤胡红波胡铨胡世聪黄代绘黄天奇黄文俊黄性涛黄晓渊黄勇黄志成季筱璐贾焕玉贾康江琨姜晓巍姜泽军金敏康明铭柯通 D.Kuleshov.K.Kurinov 李兵兵李澄李骢李丹李飞李海波李会财李华阳李军李剑李捷李凯李文龙李文莲李秀荣李昕李一卓李哲黎卓梁恩维梁云峰林苏杰刘冰刘成刘栋刘虎刘海东刘佳刘江来刘金艳刘茂元柳若愚刘四明刘伟刘怡刘以农鲁睿罗晴吕洪魁马伯强马玲玲马欣华毛基荣闵振 w.Mitthumsiri 穆慧君南云程 A.Neronov 区子维庞彬宇 p.pattarakijwanic. 裴致远齐孟尧祁业情乔冰强秦家军 D.Ruf.olo A.Sáiz.D.Semikoz.邵澄宇邵琅 O.Shc.egolev 盛祥东舒富文宋慧超 y..V.Stenkin V.Stepanov 苏扬孙秦宁孙晓娜孙志斌谭柏轩唐庆文唐泽波田文武王超王昌贝王广威王洪光王惠惠王建成汪凯王利苹王玲玉王培汉王冉王为王祥高王祥玉王阳王玉东王岩谨王忠海王仲翔王振王铮韦大明魏俊杰魏永健文韬吴超勇吴含荣武莎吴雪峰吴雨生席邵强夏捷夏君集项光漫肖迪泫肖刚辛广广辛玉良邢祎熊峥徐东莲徐仁峰徐仁新徐伟立薛良闫大海颜景志颜田杨朝文杨帆杨冯帆杨何文杨佳盈杨莉莉杨明洁杨睿智杨深邦姚玉华姚志国叶一锰尹丽巧尹娜游晓浩游智勇于艳红袁强岳华曾厚敦曾婷轩曾玮查敏张彬彬张丰张海明张恒英张建立张丽霞张力张鹏飞张佩佩张瑞张少博张少如张寿山张潇张笑鹏张云峰张毅张勇赵兵赵静赵雷赵立志赵世平郑福周斌周浩周佳能周猛周平周荣周勋秀祝成光祝凤荣朱辉朱科军左雄 lhAASO c.llaboration Key.laboratory.of.partic.e Astrophy.c.&Ex.erimental.p.y.ic. Division&c.mputing c.nter Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China University.of.c.inese Ac.demy.of.Sc.enc.s Beijing 100049China Tianf. c.smic.Ray.Researc. c.nter Chengdu 610000China Dublin Institute f.r Advanc.d Studies 31 Fitzwilliam Place2 DublinIreland Max.planc.-Institut f.r Nuc.ear phy.ic. P.O.Box 10398069029 HeidelbergGermany State Key.laboratory.of.partic.e Detec.ion and Elec.ronic. China University.of.Sc.enc. and Tec.nology.of.c.ina Hefei 230026China Sc.ool of.phy.ic.l Sc.enc. and Tec.nology.Sc.ool of.Inf.rmation Sc.enc. and Tec.nology Southwest Jiaotong UniversityChengdu 610031China Sc.ool of.Astronomy.and Spac. Sc.enc. Nanjing UniversityNanjing 210023China c.nter f.r Astrophy.ic. Guangzhou UniversityGuangzhou 510006China hebei Normal University Shijiazhuang 050024China Key.laboratory.of.Dark Matter and Spac. Astronomy.Key.laboratory.of.Radio Astronomy Purple Mountain ObservatoryChinese Academy of SciencesNanjing 210023China Tsung-Dao lee Institute&Sc.ool of.phy.ic. and Astronomy Shanghai Jiao Tong UniversityShanghai 200240China Key.laboratory.f.r Researc. in Galax.es and c.smology Shanghai Astronomical ObservatoryChinese Academy of SciencesShanghai 200030China Key.laboratory.of.c.smic.Ray.(Tibet University. Ministry of EducationLhasa 850000TibetChina National Astronomic.l Observatories Chinese Academy of SciencesBeijing 100101China Sc.ool of.phy.ic. and Astronomy.z.uhai)&Sc.ool of.phy.ic.(Guangz.ou)&Sino-f.enc. Institute of.Nuc.ear Engineering and Tec.nology.z.uhai) Sun Yat-sen UniversityZhuhai 519000&Guangzhou 510275China Sc.ool of.phy.ic. and Astronomy Yunnan UniversityKunming 650091China Département de phy.ique Nuc.éaire et c.rpusc.laire Facultéde SciencesUniversitéde Genève24 Quai Ernest Ansermet1211 GenevaSwitzerland Institute of.f.ontier and Interdisc.plinary.Sc.enc. Shandong UniversityQingdao 266237China Apc Universit'e Paris Cit'eCNRS/IN2P3CEA/IRFUObservat

The f.ll array.of.the large high Altitude Air Shower Observatory.lhAASO)has been in operation sinc. July.*** its kilometer-square array.KM2A),we optimiz.d the selec.ion c.iteria f.r very.high and ultrahigh energy.-ray. using data c.llec.ed f.om August 2021 to August 2022,resulting in an improvement in signif.c.nc. of.the detec.ion in the c.ab Nebula of.approx.mately.15%,c.mpared with that of.previous *** the implementation of.these new selec.ion c.iteria,the angular resolution was also signif.c.ntly.improved by.approx.mately.10%at tens of.*** aspec.s of.the f.ll KM2A array.perf.rmanc.,suc. as the pointing error,were also c.librated using the c.ab *** resulting energy.spec.rum of.the c.ab Nebula in the energy.range of.10-1000 TeV are well f.tted by.a log-parabola model,whic. is c.nsistent with the previous results f.om lhAASO and other ex.eriments.

关键词： γ-ray c.ab Nebula signif.c.nc.

Struc.ure-based design of.pan-c.ronavirus inhibitors targeting host c.thepsin l and c.lpain-1

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Signal Transduc.ion and Targeted Therapy 2024年第4期9卷 1651-1664页

作者： x.ong x.e Qiaoshuai lan Jiny. z.ao Sulin zhang lu liu y.min zhang wei x. Maolin Shao Jingjing peng Shuai x.a y.n z.u Keke zhang x.anglei zhang Rux.e zhang jian li wenhao Dai z.en Ge Shulei hu c.angy.e y. Jiang wang Dakota Ma Mingy.e z.eng haitao y.ng Gengf. x.ao z.h. Rao lu lu leike zhang f.ng bai y.o z.ao Shibo Jiang hong liu Drug Disc.very.and Design c.nter State Key Laboratory of Drug ResearchCAS Key Laboratory of Receptor ResearchShanghai Institute of Materia MedicaChinese Academy of SciencesShanghai 201203China University.of.c.inese Ac.demy.of.Sc.enc.s Beijing 100049China Key.laboratory.of.Medic.l Molec.lar Virology.MOE/Nhc.c.MS) School of Basic Medical SciencesShanghai Institute of Infectious Disease and BiosecurityFudan UniversityShanghai 200032China Shanghai Institute f.r Advanc.d Immunoc.emic.l Studies and Sc.ool of.lif. Sc.enc. and Tec.nology ShanghaiTech UniversityShanghai 201210China State Key.laboratory.of.Virology Wuhan Institute of VirologyCenter for Biosafety Mega-ScienceChinese Academy of SciencesWuhan 430071China Sc.ool of.c.inese Materia Medic. Nanjing University of Chinese Medicine138 Xian Lin RoadJiangsu 210023 NanjingChina Sc.ool of.pharmac.utic.l Sc.enc. and Tec.nology Hangzhou Institute for Advanced StudyUCASHangzhou 310024China National c.inic.l Researc. c.nter f.r Inf.c.ious Disease Shenzhen Third People's HospitalShenzhen 518112China

Respiratory.disease c.used by.c.ronavirus inf.c.ion remains a global health *** several SARS-c.V-2-spec.f.c.vac.ines and direc.-ac.ing antivirals are available,their ef.c.c.0}on emerging c.ronaviruses in the f.ture,inc.7}ding SARS-c.V-2 variants,might be ***-targeting antivirals provide preventive and therapeutic.strategies to overc.me resistanc. and manage f.ture outbreak of.emerging *** l(c.Sl)and c.lpain-1(c.pN1)are host c.0}teine proteases whic. play.c.uc.al roles in c.ronaviral entranc. into c.lls and inf.c.ion-related immune ***,two peptidomimetic.a-ketoamide c.mpounds,14a and 14b,were identif.ed as potent dual target inhibitors against c.Sl and *** x.ray.c.y.tal struc.ures of.human c.Sl and c.pN1 in c.mplex.with 14a and 14b revealed the c.valent binding of.a-ketoamide groups of.14a and 14b to c.5 of.c.Sl and c.15 of.*** showed potent and broad-spec.rum antic.ronaviral ac.ivities in vitro,and it is worth noting that they.ex.ibited low nanomolar potenc.0}against SARS-c.V-2 and its variants of.c.nc.rn(VOc.)with Ec.o values ranging f.om 0.80 to 161.7 nM in various *** mec.anistic.ex.loration indic.ted that they.ex.ibited antic.ronaviral ac.ivity.through bloc.ing viral ***,14a and 14b ex.ibited good oral.p.armac.kinetic.properties in mic.,rats and dogs,and f.vorable saf.ty.in *** addition,both 14a and 14b treatments demonstrated potent antiviral.p.tenc.0}against SARS-c.V-2 x.B 1.16 variant inf.c.ion in a K18-hAc.2 transgenic.mouse *** 14b also showed ef.ec.ive antiviral ac.ivity.against hc.V-Oc.3 inf.c.ion in a mouse model with a f.nal survival rate of.60%.f.rther evaluation showed that 14a and 14b ex.ibited ex.ellent antiinf.ammatory.ef.ec.s in Raw 264.7 mouse mac.ophages and in mic. with ac.te *** together,these results suggested that 14a and 14b are promising drug c.ndidates,providing novel insight into devel.p.ng pan-c.ronavirus inhibitors with anti

关键词： c.lpain overc.me entranc.

SRy.Box.transc.iption f.c.or 9 triggers y.p nuc.ear entry.via direc. interac.ion in tumors

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Signal Transduc.ion and Targeted Therapy 2024年第5期9卷 2285-2297页

作者： hui Qian c.en-hong Ding f.ng liu Shi-Jie c.en c.en-Kai huang Meng-c.ao x.ao x.a-lu hong Ming-c.en wang f.ng-z.i y.n Kai Ding y.-lu c.i bai-Nan z.eng Jin Ding c.eng luo x.n zhang wei-f.n x.e Department of.Gastroenterology Changzheng HospitalNaval Medical UniversityShanghaiChina Department of.Gastroenterology Shanghai East HospitalSchool of MedicineTongji UniversityShanghaiChina Drug Disc.very.and Design c.nter CAS Key Laboratory of Receptor ResearchState Key Laboratory of Drug ResearchShanghai Institute of Materia MedicaChinese Academy of SciencesShanghaiChina Department of.Gastroenterology First Affiliated Hospital of Nanchang UniversityNanchangChina c.inic.l c.nc.r Institute Center for Translational MedicineNaval Medical UniversityShanghaiChina

The transloc.tion of.y.p f.om the c.1}oplasm to the nuc.eus is c.itic.l f.r its ac.ivation and play. a key.role in tumor ***,the prec.se molec.lar mec.anisms governing the nuc.ear import of.y.p are not f.lly.*** this study.we have unc.vered a c.uc.al role of.SOx. in the ac.ivation of.***9 promotes the nuc.ear transloc.tion of.y.p by.direc. ***,we have identif.ed that the binding between Asp-125 of.SOx. and Arg-124 of.y.p is essential f.r SOx.-y.p interac.ion and subsequent nuc.ear entry.of.***,we have disc.vered a novel asy.metric.l dimethy.ation of.y.p at Arg-124(y.p-R124me2a)c.taly.ed by.***-R124me2a enhanc.s the interac.ion between y.p and SOx. and is assoc.ated with poor prognosis in multiple ***,we disrupted the interac.ion between SOx. and y.p using a c.mpetitive peptide,S-A1,whic. mimic. anα-helix.of.SOx. c.ntaining Asp-125.S-A1 signif.c.ntly.inhibits y.p nuc.ear transloc.tion and ef.ec.ively.suppresses tumor *** study.provides the f.rst evidenc. of.SOx. as a pivotal regulator driving y.p nuc.ear transloc.tion and presents a potential therapeutic.strategy.f.r y.p-driven human c.nc.rs by.targeting SOx.-y.p interac.ion.

关键词： interac.ion interac.ion prec.se