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Th.rapy for benign rectal anastomotic stricture after surgery for colorectal cancer: A systematic review

Laparoscopic, Endoscopic, and Robotic Surgery 2024年第4期7卷 166-173页

作者： Cao G. Wu S. Zh.ng L. Zh.ng x. Zh.u W. Department of Colorectal Surgery Sir Run Run Shaw Hospital Zhejiang University School of Medicine Hangzhou 310016 China Zh.jiang University Sch.ol of Medicine Hangzhou 310030 China Department of General Surgery Tan Tock Seng Hospital Singapore 308433 Singapore

Aim: To evaluate various treatment meth.ds for benign rectal anastomotic stricture (AS) following surgery for colorectal cancer. Meth.d: A systematic review of th. literature was conducted, focusing on studies th.t reported outcomes of different treatment modalities for benign AS. Th. PubMed, Embase, Scopus, Ch.na National Knowledge Infrastructure, and Coch.ane Library databases were search.d from January 2000 to December 2023. Th. inclusion criteria were studies involving h.man subjects, publish.d in English. and reporting on th.rapeutic outcomes for benign AS. Results: A total of 19 papers identified a range of th.rapeutic strategies, including nonoperative anastomotic dilation, endoscopic balloon dilation (EBD), transanal minimally invasive surgery (TAMIS), self-ex.andable metal stents (SEMS), endoscopic incision (EI) and newer tech.iques such.as prostate resection instrumentation. Nonoperative anastomotic dilation can serve as an initial treatment for lower AS. EI demonstrated promise in cases wh.re EBD was ineffective, providing an alternative meth.d for managing AS. TAMIS and SEMS sh.wed h.gh.r efficacy in refractory cases, with.TAMIS being particularly effective for severe fibrotic or completely closed AS. Th. use of rigid instrumentation with.an electric knife for transanal incisions demonstrated precision but lacked th. flex.bility needed for complex.procedures. Conclusion: Wh.le traditional meth.ds such.as nonoperative anastomotic dilation and EBD remain first-line treatments for benign AS, advanced tech.iques such.as EI, TAMIS, and SEMS offer promising alternatives, particularly in refractory cases. Th. ch.ice of treatment sh.uld be tailored to individual patient conditions, with.consideration for th. tech.ical ex.ertise required and th. potential for complications. © 2024 Zh.jiang University

关键词： Colorectal cancer Rectal anastomotic stricture Th.rapy

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Effects of PI3-k/Akt sh.rt h.irpin RNA on proliferation, fibronectin production and synth.sis of th.ombospondin-1 and transforming growth.factor-beta（1 ） in glomerular mesangial cells induced by sublytic C5b-9 complex.s

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南京医科大学学报（自然科学版） 2009年第3期29卷 344-344页

作者： Gao, L. Zh.ng, Y. Qiu, W. x., W. Feng, x. Ren, J. Jiang, x. Wang, h. Zh.o, D. Wang, Y. Nanjing Med Univ Dept Microbiol & Immunol Nanjing 210029 Peoples R China.

To ex.lore proliferation of glomerular mesangial cells (GMC) and secretion of ex.racelluar matrix.(fibronectin induced by sublytic C5b-9 complex.s), and th.n ascertain th. role of ph.sph.tidylinositol 3-kinase(PI3-k)/Akt signal path.ay in th.se processes, by using small h.irpin RNAs. Th. ex.ression of cyelin D-2, h.3-th.midine into DNA and production of fibronectin including th.ombospondin-1 and transforming growth.factor-beta (1) in th. GMCs stimulated by sublytie C5b-9 or transfected with.ex.ression vectors of PI3-k and Akt sh.rt h.irpin RNA or LY294002(PI3-k inh.bitor) were measured by Real-time quantitative polymerase ch.in reaction(PCR), Western blot, enzyme-linked immunosorbent assay(ELISA) and h.3-th.midine incorporation(h.3-TdR), respectively. Th. ex.ression of cyclin D-2, h.3-th.midine into DNA and fibronectin in th. GMCs stimulated by sublytic C5b-9 could all be increased, and th. elevations of th.se parameters mentioned above were also markedly reduced in th. GMCs transfected with.vectors of PI3-k and Akt sh.rt h.irpin RNA or LY294002, respectively. Th.se data indicate th.t sublytic C5b-9 can promote proliferation of GMCs and secretion of fibronectin as well as synth.sis of th.ombospondin-1 and transforming growth.factor-beta (1). Th. PI3-k/Akt signal path.ay in th.se reactions, mediated by sublytic C5b-9 complex.s, may play at least a partial role.

关键词：连接蛋白凝血栓蛋白临床分析治疗方法白血病

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h.rd yet tough.and self-lubricating(CuNiTiNbCr)C_(x. h.gh.entropy nanocomposite films:Effects of carbon content on structure and properties

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Journal of Materials Science & Tech.ology 2024年第6期173卷 20-30页

作者： Y.T.Li x.M.Ch.n x.K.Zeng M.Liu x.Jiang Y.x.Leng Key Laboratory of Advanced Tech.ologies of Materials Ministry of EducationSchool of Materials Science and EngineeringSouthwest Jiaotong UniversityChengdu 610031China Key Laboratory of Noise and Vibration Research Institute of AcousticsChinese Academy of SciencesBeijing 100190China State Key Laboratory of Acoustics Institute of AcousticsChinese Academy of SciencesBeijing 100190China Sch.ol of Mech.nical and Electrical Engineering Mianyang Teachers’CollegeMianyang 621000China

Th. single-ph.se h.gh.entropy alloy film is difficult to meet severe friction conditions due to its low h.rdness and h.gh.friction ***-composite structure film is composed of at least two separated ph.ses,sh.wing th. properties of strength.and tough.ess integration and ex.ellent wear *** design of nanocomposite structures can effectively improve th. mech.nical properties and tribological properties of h.gh.entropy alloy *** th.s study,th.(CuNiTiNbCr)C_(x. nanocomposite h.gh.entropy films(h.Fs)integrated with.h.gh.h.rdness,h.gh.tough.ess,and self-lubrication were synth.sized by th. double-target co-sputtering *** effect of carbon content on microstructure,mech.nical properties,and tribological properties of(CuNiTiNbCr)C_(x. films was *** th. increase of carbon content in th. h.Fs,th. carbon atoms preferentially react with.Ti,Nb,and Cr to form a(TiNbCr)C ceramic-reinforced ph.se,and th.n th. ex.ess carbon atoms precipitate in th. form of amorph.us carbon(a-C)lubricating ph.se in th. *** structure of th. h.Fs ch.nges from an amorph.us structure to a nanocomposite structure of amorph.us(amorph.us CuNiTiNbCr ph.se+a-C ph.se)/nanocrystalline(TiN-bCr)C *** th. carbon content is about 21.2 at.%,th. carbide ph.se in th. film reach.s saturation and th. h.rdness and modulus of th. films are h.gh.st,wh.ch.are 18 GPa and 228 GPa,*** h.Fs with.a carbon content of 44.0 at.%sh.w th. best tough.ess and tribological properties with.a friction coefficient of 0.16 and a wear rate of 2.4×10^(-6) mm^(3)/(N m),wh.ch.is mainly attributed to th. ex.ellent resistance to fatigue crack growth.and th. interfacial lubricating layer formed in th. friction *** nanocomposite(CuNiTiNbCr)C_(x. h.Fs sh.w very promising application prospect in th. field of friction protection.

关键词： h.gh.entropy films Nanocomposite Double-target co-sputtering Strength.ning-tough.ning Tribological properties

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Effect of cold-working on corrosion induced damage in lug joints

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Defence Tech.ology（防务技术） 2024年第6期36卷 175-182页

作者： Ramanath.M.N Ch.kmath.L. Murth. h. Department of Aerospace Engineering Indian Institute of Technology-MadrasChennai 600036India Department of Aeronautical Engineering KLS Gogte Institute of TechnologyBelagavi 590008India

Lug joints are preferred joineries for transferring h.avy loads to parent components in aerospace *** ex.erience corrosion due to environmental conditions,improper surface finish.s and rubbing displacement between th. pin and *** causes damage of different sizes and sh.pes near th. *** degradation due to corrosion-induced damage is modelled as a th.ough.pit at one of th. identified critical locations th.ough.stress *** effect of th.s pit on fatigue crack initiation life is ***-h.le is pre-stressed by cold-working and th. benefits of inducing plastic wake on th. intended performance of th. lug joint during th. damages due to corrosion are brough. out and compared with.non-cold-worked *** analysis is performed on th.s lug joint with.*** results obtained h.gh.igh. th. benefits of cold-working and th. meth.dology can be ex.ended to damage growth.and analyse th. effect of surface treatments for better structural integrity of components of aerospace veh.cles.

关键词： Lug joint Corrosion Crack initiation Cold-working Structural integrity

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Intracellular tat of h.man immunodeficiency virus type 1 activates lytic cycle replication of Kaposi＇s sarcoma-associated h.rpesvirus. Role of JAK/STAT signaling

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南京医科大学学报（自然科学版） 2007年第5期27卷 514-514页

作者： Zeng, Y. Zh.ng, x. h. h.ang, Z. Ch.ng, L. Yao, S. h. Qin, D. Ch.n, x. Y. Tang, Q. Lv, Z. G. Zh.ng, L. Lu, C. Nanjing Med Univ Dept Microbiol ＆ Immunol Nanjing 210029 Peoples R China Nanjing Med Univ Lab Reprod Med Nanjing 210029 Peoples R China Nanjing Med Univ Jiangsu Prov Lab Pathogen Biol Nanjing 210029 Peoples R China Youjiang Med Coll Nationalities Dept Microbiol ＆ Immunol Bose 533000 Peoples R China A nh.i Sci ＆ Tech.ol Univ Coll A nim Sci Fengyang 233100 Peoples R China Univ Ch.cago Ben May Inst Caac Res Chicago IL 60637 USA

h.man immunodeficiency virus typeⅠ(h.V-1) infection significantly increases th. risk of Kaposi's sarcoma(KS) occurrence in individuals infected with.Kaposi's sarcoma-associated h.rpesvirus(KSh.)。KSh. infection appears to be necessary but not sufficient for KS development with.ut oth.r cofactors。h.wever, factors th.t facilitate KSh. to cause KS h.ve not been well defined。Previously, we determined th.t h.man h.rpesvirus 6 was one of th. cofactors th.t activated lytic cycle replication of KSh.。h.re, we demonstrate th.t th. Tat protein of h.V-1 is a potentially important factor in th. path.genesis of KS, as determined by production of lyric ph.se mRNA transcripts and viral proteins in BCBL-1 cells。

关键词：免疫缺陷性病毒1 疱疹病毒肉瘤 JAK/STAT信号 h.V-1 T细胞转录因子基因表达

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Ab initio calculation of th. lattice dynamics of th. single-bonded cubic nitrogen

Ab initio calculation of the lattice dynamics of the single-...

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中国化学会第九届全国量子化学学术会议

作者： h. L. Yu, G.W. Yang, Y. x.ao, x. h. Yan, Y. L. Mao, Y. R. Yang, M. x. Ch.ng, Y, Zh.ng Key Laboratory for Advanced Materials and Rh.logical Properties, Ministry of Education, Institute of Modern Ph.sics, x.angtan University, x.angtan 411105 State key laboratory of optoelectronic materials and tech.ologies, Sch.ol of Ph.s. & Eng., Zh.ngsh.n University, Guangzh.u 510275

＜正＞We present a first principles calculation of lattice dynamical properties of single-bonded cubic nitrogen. Our calculations h.ve been performed using density-functional perturbation th.ory togeth.r with.plane-wave ex.ansion and nonlocal pseudopotentials. As a first step we h.ve evaluated th. equilibrium structure of single-bonded cubic nitrogen via th. minimization of th. total energy.

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Rational design of AgGaS/ZnS/ZnS quantum dots with.a near-unity ph.toluminescence quantum yield via double sh.lling sch.me

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Journal of Materials Science & Tech.ology 2024年第2期169卷 235-242页

作者： h.x.Lu h.Liu Z.Z.Fu Y.Y.Ch.n h.Q.Dai Z.h. W.L.Zh.ng R.Q.Guo Institute for Electric Ligh. Sources School of Information Science and TechnologyFudan UniversityShanghai 200433China Institute of Future Ligh.ing Academy for Engineering and TechnologyFudan UniversityShanghai 200433China Yiwu Research.Institute of Fudan University YiwuZhejiang 322000China Zh.ngsh.n-Fudan Joint Innovation Center Zhongshan 528437China

In th.s study,a two-step meth.d was used to synth.size h.gh.y luminescent AgGaS/ZnS/ZnS quantum dots(QDs).In th. first step,an inner ZnS sh.ll was formed via a one-pot meth.d,wh.ch.resulted in a smaller lattice mismatch.between th. AgGaS core and th. outer ZnS sh.ll,th.reby facilitating th. formation of a th.ck outer *** th. two-step sh.lling process,th. synth.sized AgGaS/ZnS/ZnS QDs sh.wed an ex.ellent ph.toluminescence quantum yield(PLQY)of 96.4%with.a peak wavelength.of 508 nm,repre-senting th. h.gh.st PLQY reported th.s far for AgGaS ***,th. effect of h.logen ions in Zn precursors on th. sh.lling process was *** was proposed th.t th. capacity of h.logen ions to coordinate with.th. QDs influenced th. balance between Zn cation diffusion and ZnS sh.lling ***,th. ZnS sh.lling reaction was dominant wh.n ZnCl_(2)was employed,wh.le Zn cation diffusion was th. dominant process under th. I^(−)-rich.*** work provides insigh.s into th. interfacial restructuring during th. ZnS sh.lling and offers a clear map for th. tailored synth.sis of core/sh.ll QDs.

关键词： AgGaS Quantum dots Ph.toluminescence Core/sh.ll Alloyed core/sh.ll interface

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Editorial for th. Special Issue on Emerging Tech.ology and Advanced Application of Nondestructive Detection for Power Equipment

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Ch.nese Journal of Electrical Engineering 2024年第1期10卷 1-2页

作者： Li J. Mei h. Li S. Tianjin University China Tsingh.a Sh.nzh.n International Graduate Sch.ol China Lanzh.u Jiaotong University China

Th. rapid development of clean and renewable energy tech.ologies represented by wind and solar energy,as well as th. continuous growth.of load demand,h.ve put forward h.gh.r requirements for th. safe operation of th. power *** performance of power equipment based on traditional dielectric materials is often limited by various defects generated during molding,transportation,assembly,and operation,wh.ch.cannot meet th. reliability requirements of power systems in th. new *** detection is an essential tech.ical meth.d in industrial development,wh.ch.can detect and evaluate th. defect and damage status of in-service equipment,key components,and materials with.ut damaging th. object.

关键词： service Application operation

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Th. Monolith.c Glass-Ceramic Lined Steel Elbow Made by Sh. Gravitational-Th.rmite Process

The Monolithic Glass-Ceramic Lined Steel Elbow Made by SHS G...

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Th. 3～〔rd〕International Conference on h.gh.Performance Ceramics(CICC-3)（2）

作者： S.-x. Wang W.-Y. Gao T.-C. Ma K.-M. Liang and x.-h. Zh.ngDepart. Mater. Sci. and Eng. Dalian Institute of Ligh. Industry Dalian 116034 P.R. Ch.na Depart. Mater. Sci. and Eng. Tsingh.a University Beijing 100084 P.R. Ch.na

＜正＞ A monolith.c glass-ceramic lined steel elbow with.90°-bend angle was fabricated using a self-propagating h.gh.temperature synth.sis gravitational-th.rmite process （Sh. G-T process）. Th. manufacture principle and some tech.ologies were introduced. Ex.eriment results sh.wed th.t th. inner surface of th. composite elbow was smooth.and th.re were no visible cracks and pores in it. Th. coating layer was symmetry and was of-2.5 mm th.ck. It consisted of two zones （glass-like zone, columnar zone） and th.t th.re ex.sted th.ee ph.ses （Al2O3, glass and Fe particles） in both.of th. two zones. h.wever, th. Al2O3 grains were different evidently in th. two zones. x.D results sh.wed th.t th.re was no h.rcynite ph.se in th. coating layer.

关键词： Self-propagating h.gh.temperature synth.sis Coatings Wear Elbow

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Demand-Responsive Transportation Veh.cle Routing Optimization Based on Two-Stage Meth.d

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Computers, Materials and Continua 2024年第1期81卷 443-469页

作者： Ma J. Liu h. Ch.n L. Sch.ol of Railway Transportation Shanghai Institute of Technology Shanghai 201418 China

Demand-responsive transportation (DRT) is a flex.ble passenger service designed to enh.nce road efficiency, reduce peak-h.ur traffic, and boost passenger satisfaction. h.wever, ex.sting optimization meth.ds for initial passenger requests fall sh.rt in addressing real-time passenger needs. Consequently, th.re is a need to develop real-time DRT route optimization meth.ds th.t integrate both.initial and real-time requests. Th.s paper presents a two-stage, multi-objective optimization model for DRT veh.cle sch.duling. Th. first stage involves an initial sch.duling model aimed at minimizing veh.cle configuration, and operational, and CO2 emission costs wh.le ensuring passenger satisfaction. Th. second stage develops a real-time sch.duling model to minimize additional operational costs, penalties for time window violations, and costs due to rejected passengers, th.reby addressing real-time demands. Additionally, an enh.nced genetic algorith. based on Non-dominated Sorting Genetic Algorith.-II (NSGA-II) is designed, incorporating multiple crossover points to accelerate convergence and improve solution efficiency. Th. proposed sch.duling model is validated using a real network in Sh.ngh.i. Results indicate th.t real-time sch.duling can serve more passengers, and improve veh.cle utilization and occupancy rates, with.only a minor increase in total operational costs. Compared to th. traditional NSGA-II algorith., th. improved version enh.nces convergence speed by 31.7% and solution speed by 4.8%. Th. proposed model and algorith. offer both.th.oretical and practical guidance for real-world DRT sch.duling. © 2024 Th. Auth.rs.

关键词： artificial intelligence applications Demand responsive transit genetic algorith. muti-objective optimization

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