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A Review of Deep Learning-Based Vulnerability Detection Tools for Ethernet Smart Contracts

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Computer Modeling in Engineering & Sciences 2024年第7期140卷 77-108页

作者： Huaiguang wu yibo Peng Yaqiong He Jinlin Fan School of Computer Science and Technology Zhengzhou University of Light IndustryZhengzhou450001China

In recent years,the number of smart contracts deployed on blockchain has ***,the issue of vulnerability has caused incalculable *** to the irreversible and immutability of smart contracts,vulnerability detection has become particularly *** the popular use of neural network model,there has been a growing utilization of deep learning-based methods and tools for the identification of vulnerabilities within smart *** paper commences by providing a succinct overview of prevalent categories of vulnerabilities found in smart ***,it categorizes and presents an overview of contemporary deep learning-based tools developed for smart contract *** tools are categorized based on their open-source status,the data format and the type of feature extraction they *** we conduct a comprehensive comparative analysis of these tools,selecting representative tools for experimental validation and comparing them with traditional tools in terms of detection coverage and ***,Based on the insights gained from the experimental results and the current state of research in the field of smart contract vulnerability detection tools,we suppose to provide a reference standard for developers of contract vulnerability detection ***,forward-looking research directions are also proposed for deep learning-based smart contract vulnerability detection.

关键词： Smart contract vulnerability detection deep learning

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中国社区肿瘤患者抑郁症状现况调查

中国心理卫生杂志 2024年第1期38卷 55-62页

作者：李涵云李秀婷许瑞雪慕福芹秦岩黄悦勤吴一波刘燕山东大学齐鲁医学院济南250012 济宁医学院精神卫生学院山东济宁272013 济宁市妇幼保健计划服务中心山东济宁272000 滨州医学院公共卫生与管理学院山东烟台264003 山东第一医科大学公共卫生与健康管理学院济南250117 北京大学第六医院北京大学精神卫生研究所国家卫生健康委员会精神卫生学重点实验室(北京大学)国家精神心理疾病临床医学研究中心(北京大学第六医院)北京100083 北京大学公共卫生学院北京100191

目的:探讨社区肿瘤患者抑郁症状现况及相关因素。方法:在全国范围内(不包含港澳台)以分层抽样与按全国第7次人口普查比例配额抽样相结合的方法抽取30505例居民。采用中文版患者健康问卷-9、广泛性焦虑障碍量表、自编调查问卷、简化版领... 详细信息

目的:探讨社区肿瘤患者抑郁症状现况及相关因素。方法:在全国范围内(不包含港澳台)以分层抽样与按全国第7次人口普查比例配额抽样相结合的方法抽取30505例居民。采用中文版患者健康问卷-9、广泛性焦虑障碍量表、自编调查问卷、简化版领悟社会支持量表等评估肿瘤患者抑郁症状、焦虑症状、行为方式、社会支持情况等。结果:自我报告临床诊断肿瘤患者共359例(1.2%)。其中,恶性肿瘤患者151例(42.1%),良性肿瘤患者208例(57.9%),肿瘤患者的抑郁症状检出率76.6%。过去1周内每天走路超过10min少于3d(OR=6.63)或4~6d(OR=5.00)、整体睡眠质量很差(OR=4.80)或一般(OR=3.06)、领悟朋友支持程度低(OR=4.66)及伴有焦虑症状(OR=1.74)是肿瘤患者抑郁症状的危险因素。结论:肿瘤患者抑郁症状检出率较高,特别是睡眠质量差、运动量少、领悟社会支持低的患者。

关键词：肿瘤抑郁症状相关因素

Numerical investigation of hydro-morphodynamic characteristics of a cascading failure of landslide dams

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Journal of Mountain Science 2024年第6期21卷 1868-1885页

作者： ZHONG Qiming CHEN Lingchun MEI Shengyao SHAN yibo wu Hao ZHAO Kunpeng Department of Geotechnical Engineering Nanjing Hydraulic Research InstituteNanjing 210024China National Key Laboratory of Water Disaster Prevention Nanjing 210098China Key Laboratory of Reservoir and Dam Safety of the Ministry of Water Resources Nanjing 210029China

A cascading failure of landslide dams caused by strong earthquakes or torrential rains in mountainous river valleys can pose great threats to people’s lives,properties,and *** this study,based on the three-dimensional Reynoldsaveraged Navier-Stokes equations(RANS),the renormalization group(RNG)k-εturbulence model,suspended and bed load transport equations,and the instability discriminant formula of dam breach side slope,and the explicit finite volume method(FVM),a detailed numerical simulation model for calculating the hydro-morphodynamic characteristics of cascading dam breach process has been *** developed numerical model can simulate the breach hydrograph and the dam breach morphology evolution during the cascading failure process of landslide dams.A model test of the breaches of two cascading landslide dams has been used as the validation *** comparison of the calculated and measured results indicates that the breach hydrograph and the breach morphology evolution process of the upstream and downstream dams are generally consistent with each other,and the relative errors of the key breaching parameters,i.e.,the peak breach flow and the time to peak of each dam,are less than±5%.Further,the comparison of the breach hydrographs of the upstream and downstream dams shows that there is an amplification effect of the breach flood on the cascading landslide dam *** key parameters,i.e.,the distance between the upstream and the downstream dams,the river channel slope,and the downstream dam height,have been used to study the flood amplification *** parameter sensitivity analyses show that the peak breach flow at the downstream dam decreases with increasing distance between the upstream and the downstream dams,and the downstream dam ***,the peak breach flow at the downstream dam first increases and then decreases with steepening of the river channel *** the flood caused by the upstream dam failure flows to the

关键词： Cascading landslide dams Cascading dam failure process Detailed numerical simulation model Flood amplification effect Parameter sensitivity analyses

The OsCLV2s-OsCRN1 co-receptor regulates grain shape in rice

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Journal of Genetics and Genomics 2024年第7期51卷 691-702页

作者： Xingxing Li Meng-en wu Juncheng Zhang Jingyue Xu Yuanfei Diao yibo Li National Key Laboratory of Crop Genetic Improvement and National Centre of Plant Gene Research(wuhan) Huazhong Agricultural UniversityWuhanHubei 430070China Hubei Hongshan Laboratory WuhanHubei 430070China

The highly conserved CLV–wuS negative feedback pathway plays a decisive role in regulating stem cell maintenance in shoot and floral meristems in higher plants,including Arabidopsis,rice,maize,and ***,we find significant natural variations in the OsCLV2c,OsCLV2d,and OsCRN1 loci in a genome-wide association study of grain shape in ***2a,OsCLV2c,OsCLV2d,and OsCRN1 negatively regulate grain length–width ratio and show distinctive geographical distribution,indica–japonica differentiation,and artificial selection ***,OsCLV2a and OsCRN1 interact biochemically and genetically,suggesting that the two components function in a complex to regulate grain shape of ***,the genetic contributions of the haplotypes combining OsCLV2a,OsCLV2c,and OsCRN1 are significantly higher than those of each single gene alone in controlling key yield *** findings identify two groups of receptor-like kinases that may function as distinct co-receptors to control grain size in rice,thereby revealing a previously unrecognized role of the CLV class genes in regulating seed development and proposing a framework to understand the molecular mechanisms of the CLV–wuS pathway in rice and other crops.

关键词： Rice Grain shape OsCLV2s OsCRN1 Natural variations Indica-japonica differentiation

The expression and localization of a novel protein phosphatase inhibitor 2810408A11Rik in mouse testis and sperm

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The Journal of Biomedical Research 2012年第2期26卷 110-116页

作者： Ye Bi Mingxi Liu Wenjiao Tu yibo wu Xuejiang Guo Zuomin Zhou Jiahao Sha State Key Laboratory of Reproductive Medicine Department of Histology and EmbryologyNanjing Medical UniversityNanjingJiangsu 210029China

This study investigated the expression and distribution of 2810408A11Rik in mouse testis and sperm, and explored its role in sperrnatogenesis and sperm function. The expression levels of 2810408A11Rik mRNA in multiple tissue samples were analyzed using bioinformatic resources and RT-PCR technique. A specific rabbit polyclonal antibody was prepared by prokaryotic expression of 2810408A11Rik recombinant protein and utilized for animal immunization. Western blotting, immunohistochemistry and immunofluorescence were used to detect the expression and distribution of 2810408A11Rik. The results of the bioinformatic analysi and RT-PCR showed that 2810408A11Rik mRNA was specifically expressed in mouse testis, and 2810408AllRik protein included a protein phosphatase inhibitor domain. Western blotting assays, immunohistochemistry and immunofluorescence confirmed the expression of 2810408A11Rik protein in mouse testis, especially in post-meiosis round and long spermatids, and that it is localized in the acrosome and the post-nucleus area of sperm. Our findings suggest that 2810408A11Rik may play an important role in spermatogenesis, sperm capacitation and fertilization.

关键词： 2810408A11Rik testis specific protein phosphatase inhibitor capacitation

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老年慢性病患者生命质量现状及影响因素研究

卫生经济研究 2024年第4期41卷 39-42页

作者：司俊霄姚依松何景波姜茂敏黄新城张熠扬廖坤锋李丹吴一波贵州财经大学公共管理学院贵州贵阳550025 川北医学院四川省基层卫生事业发展研究中心四川南充637000 青岛大学第四临床医学院山东烟台264001 厦门大学公共事务学院福建厦门361005 北京印刷学院经济管理学院北京102600 广西中医药大学护理学院广西南宁530000 北京大学公共卫生学院北京100191

目的:了解我国老年慢性病患者的生命质量状况,探究其影响因素,为制定相关政策提供依据。方法:采用多阶段抽样方法,针对120个城市的居民进行横断面研究;应用量表进行问卷调查,探究老年慢性病患者抑郁、自我效能、疾病感知与生命质量的相... 详细信息

目的:了解我国老年慢性病患者的生命质量状况,探究其影响因素,为制定相关政策提供依据。方法:采用多阶段抽样方法,针对120个城市的居民进行横断面研究;应用量表进行问卷调查,探究老年慢性病患者抑郁、自我效能、疾病感知与生命质量的相关性;运用多元线性回归方法分析老年慢性病患者生命质量的影响因素。结果:老年慢性病患者生命质量得分为22.90±2.81分,已婚、周围有基层医疗卫生机构的老年慢性病患者生命质量较高,疾病感知与抑郁对老年慢性病患者生命质量产生显著负向影响,自我效能对老年慢性病患者生命质量产生显著正向影响。结论:我国老年慢性病患者生命质量偏低,应加强居家照护,提升基层医疗卫生服务能力,开展健康教育,综合提升老年人的健康素养。

关键词：慢性病老年人生命质量疾病感知抑郁自我效能

继发急性髓系白血病异基因造血干细胞移植疗效及预后影响因素分析

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中华血液学杂志 2024年第1期45卷 41-47页

作者：袁晓琳吴一波宋晓露陈怡陆滢来晓瑜施继敏刘丽珍赵妍敏余建杨露欣蓝建平蔡真黄河罗依浙江大学医学院附属第一医院骨髓移植中心、良渚实验室、浙江大学血液学研究所、浙江省干细胞与细胞免疫治疗工程实验室杭州310003 浙江省人民医院杭州310014 温州医科大学附属第一医院温州325035 宁波大学附属人民医院宁波315000

目的探讨成人继发急性髓系白血病(AML)接受异基因造血干细胞移植(allo-HSCT)的疗效及预后影响因素。方法多中心回顾性临床研究。纳入2014年1月至2022年11月因继发AML在浙江省造血干细胞移植协作组4个中心接受allo-HSCT的18岁以上的成人... 详细信息

目的探讨成人继发急性髓系白血病(AML)接受异基因造血干细胞移植(allo-HSCT)的疗效及预后影响因素。方法多中心回顾性临床研究。纳入2014年1月至2022年11月因继发AML在浙江省造血干细胞移植协作组4个中心接受allo-HSCT的18岁以上的成人患者,并进行疗效及预后影响因素分析。结果共纳入95例患者,其中66例(69.5%)为骨髓增生异常综合征(MDS)转化AML(MDS-AML),4例(4.2%)为MDS/骨髓增殖性肿瘤(MPN)转化AML(MDS/MPN-AML),25例(26.3%)为治疗相关AML(tAML)。所有患者的3年累积复发率(CIR)、无白血病生存(LFS)率和总生存(OS)率分别为18.6%(95%CI 10.2%~27.0%)、70.6%(95%CI 60.8%~80.4%)和73.3%(95%CI 63.9%~82.7%)。M-AML(包括MDS-AML、MDS/MPN-AML)组和tAML组的3年CIR分别为20.0%和16.4%(P=0.430);3年LFS率分别为68.3%和75.4%(P=0.176);3年OS率分别为69.7%和75.4%(P=0.233),两组间差异均无统计学意义。TP53突变组和无TP53突变组的3年CIR分别为60.0%和13.7%(P=0.003),3年LFS率分别为20.0%和76.5%(P=0.002),3年OS率分别为40.0%和77.6%(P=0.002)。根据2022欧洲白血病网(ELN2022)危险分层,低危、中危和高危3组患者的3年CIR分别为8.3%、17.8%和22.6%(P=0.639),3年LFS率分别为91.7%、69.5%和65.6%(P=0.268),3年OS率分别为91.7%、71.4%和70.1%(P=0.314)。多因素分析表明,移植时疾病未缓解和伴有TP53突变是影响患者CIR、LFS和OS的独立危险因素。结论M-AML组(MDS-AML、MDS/MPN-AML)与tAML组患者allo-HSCT预后相近。移植时疾病未缓解和伴有TP53突变是不良预后因素。ELN2022危险分层对继发AML患者allo-HSCT预后的预测价值有限。

关键词：白血病髓系急性继发白血病造血干细胞移植生存复发

Real time observation of the photocleavage of single DNA molecules

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Chinese Science Bulletin 2003年第7期48卷 673-675页

作者： LI Bin , HU Jun , WANG Ying, wu Shiying, HUANG yibo & LI Minqian Shanghai Institute of Nuclear Research,Chinese Academy of Sciences, Shanghai 201800,China Shanghai Institute of Nuclear Research Chinese Academy of Sciences Shanghai 201800 China

A method for real time observation of photo-cleavage of stretched λDNA at single molecular level by a fluorescent microscope coupled with CCD is developed. DNA molecules stained with YOYO-1 are stretched by the mo-lecular combing technique and fixed on a modified slide. Then the process of photocleavage and relaxation of DNA under radiation of blue light is observed. We speculate that the conformation change of stretched DNA and the effect of water are likely to facilitate the effect of YOYO photocleav-age DNA molecules. The photocleavage effect of YOYO for stretched DNA may be useful to study DNA elasticity, cancer research as well as the interaction between DNA and dyes.

关键词：单个DNA分子光致断裂原子力显微镜荧光显微镜实时观察生物大分子

Heterogeneous population distribution enhances resistance to wheat lodging by optimizing the light environment

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Journal of Integrative Agriculture 2024年第7期23卷 2211-2226页

作者： yibo Hu Feng Qin Zhen wu Xiaoqin Wang Xiaolong Ren Zhikuan Jia Zhenlin Wang Xiaoguang Chen Tie Cai College of Agronomy Northwest A&F UniversityYangling 712100China Key Laboratory of Crop Physi-Ecology and Tillage Science in Northwestern Loess Plateau Ministry of Agriculture and Rural AffairsNorthwest A&F UniversityYangling 712100China College of Agronomy Shandong Agricultural University/State Key Laboratory of Crop BiologyTai’an 271018China Xuzhou Institute of Agricultural Sciences in Jiangsu Xuhuai Area Xuzhou 221131China

Lodging is still the key factor that limits continuous increases in wheat yields today,because the mechanical strength of culms is reduced due to low-light stress in populations under high-yield *** mechanical properties of the culm are mainly determined by lignin,which is affected by the light ***,little is known about whether the light environment can be sufficiently improved by changing the population distribution to inhibit culm ***,in this study,we used the wheat cultivar“Xinong 979”to establish a low-density homogeneous distribution treatment(LD),high-density homogeneous distribution treatment(HD),and high-density heterogeneous distribution treatment(HD-h)to study the regulatory effects and mechanism responsible for differences in the lodging resistance of wheat culms under different population *** with LD,HD significantly reduced the light transmittance in the middle and basal layers of the canopy,the net photosynthetic rate in the middle and lower leaves of plants,the accumulation of lignin in the culm,and the breaking resistance of the culm,and thus the lodging index values increased significantly,with lodging rates of 67.5%in 2020–2021 and 59.3%in 2021–*** HD-h,the light transmittance and other indicators in the middle and basal canopy layers were significantly higher than those under HD,and the lodging index decreased to the point that no lodging *** with LD,the activities of phenylalanine ammonia-Lyase(PAL),4-coumarate:coenzyme A ligase(4CL),catechol-O-methyltransferase(COMT),and cinnamyl-alcohol dehydrogenase(CAD)in the lignin synthesis pathway were significantly reduced in the culms under HD during the critical period for culm formation,and the relative expression levels of TaPAL,Ta4CL,TaCOMT,and TaCAD were significantly ***,the activities of lignin synthesis-related enzymes and their gene expression levels were significantly increased under HD-h compare

关键词： canopy light environment lignin lodging population distribution wheat