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Pulses in ground motions identified through surface partial matching and their impact on seismic rocking consequence

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Earthquake Engineering and Engineering Vibration 2024年第1期23卷 35-50页

作者： Tang Yuchuan Wang jiankang wu Gang School of Civil Engineering Southeast UniversityKey Laboratory of Concrete and Prestressed Concrete Structures of the Ministry of EducationNanjing 211102China National and Local Joint Engineering Research Center for Intelligent Construction and Maintenance Nanjing 211102China

In seismology and earthquake engineering,it is fundamental to identify and characterize the pulse-like features in pulse-type ground *** capture the pulses that dominate structural responses,this study establishes congruence and shift relationships between response spectrum surfaces.A similarity search between spectrum surfaces,supplemented with a similarity search in time series,has been applied to characterize the pulse-like features in pulse-type ground *** identified pulses are tested in predicting the rocking consequences of slender rectangular blocks under the original ground ***,the prediction is promising for the majority of the ground motions where the dominant pulse is correctly identified.

关键词： velocity pulse ground motion surface similarity rocking overturning

A Prediction-Based Multi-Objective VM Consolidation Approach for Cloud Data Centers

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Computers, Materials & Continua 2024年第7期80卷 1601-1631页

作者： Xialin Liu Junsheng wu lijun Chen Jiyuan Hu School of Computer Science Northwestern Polytechnical UniversityXi’an710005China School of Computer Science and Technology Xi’an University of Posts and TelecommunicationsXi’an710021China Shaanxi Key Laboratory of Network Data Analysis and Intelligent Processing Xi’an University of Posts and TelecommunicationsXi’an710021China School of Software and Microelectronics Northwestern Polytechnical UniversityXi’an710005China School of Automation Xi’an University of Posts and TelecommunicationsXi’an710021China

Virtual machine(VM)consolidation aims to run VMs on the least number of physical machines(PMs).The optimal consolidation significantly reduces energy consumption(EC),quality of service(QoS)in applications,and resource *** paper proposes a prediction-basedmulti-objective VMconsolidation approach to search for the best mapping between VMs and PMs with good timeliness and practical *** use a hybrid model based on Auto-Regressive Integrated Moving Average(ARIMA)and Support Vector Regression(SVR)(HPAS)as a prediction model and consolidate VMs to PMs based on prediction results by HPAS,aiming at minimizing the total EC,performance degradation(PD),migration cost(MC)and resource wastage(RW)*** results usingMicrosoft Azure trace show the proposed approach has better prediction accuracy and overcomes the multi-objective consolidation approach without prediction(i.e.,Non-dominated sorting genetic algorithm 2,Nsga2)and the renowned Overload Host Detection(OHD)approaches without prediction,such as Linear Regression(LR),Median Absolute Deviation(MAD)and Inter-Quartile Range(IQR).

关键词： VM consolidation prediction multi-objective optimization machine learning

Effects of projectile parameters on the momentum transfer and projectile melting during hypervelocity impact

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Defence Technology（防务技术） 2024年第2期32卷 89-103页

作者： Wenjin Liu Qingming Zhang Renrong Long Zizheng Gong Ren jiankang Xin Hu Siyuan Ren Qiang wu Guangming Song State Key Laboratory of Explosion Science and Technology Beijing Institute of TechnologyBeijing100081China Beijing Institute of Spacecraft Environment Engineering China Academy of Space TechnologyBeijing100094China

The effects of projectile/target impedance matching and projectile shape on energy,momentum transfer and projectile melting during collisions are investigated by numerical *** comparing the computation results with the experimental results,the correctness of the calculation and the statistical method of momentum transfer coefficient is *** shapes of aluminum,copper and heavy tungsten alloy projectiles striking aluminum,basalt,and pumice target for impacts up to 10 km/s are *** influence mechanism of the shape of the projectile and projectile/target density on the momentum transfer was *** an increase in projectile density and length-diameter ratio,the energy transfer time between the projectile and targets is *** projectile decelerates slowly,resulting in a larger cratering *** energy consumed by the projectile in the excavation stage increased,resulting in lower mass-velocity of ejecta and momentum transfer *** numerical simulation results demonstrated that for different projectile/target combinations,the higher the wave impedance of the projectile,the higher the initial phase transition velocity and the smaller the mass of phase *** results can provide theoretical guidance for kinetic impactor design and material selection.

关键词： Hypervelocity impact Energy partitioning Impact melting Momentum transfer

Dual-Schottky-junctions coupling device based on ultra-longβ-Ga_(2)O_(3)single-crystal nanobelt and its photoelectric properties

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Journal of Semiconductors 2024年第5期45卷 90-98页

作者： Haifeng Chen Xiaocong Han Chenlu wu Zhanhang Liu Shaoqing Wang Xiangtai Liu Qin lu Yifan Jia Zhan Wang Yunhe Guan lijun Li Yue Hao Key Laboratory of Advanced Semiconductor Devices and Materials School of Electronic EngineeringXi’an University of Posts andT elecommunicationsXi’an 710121China State Key Discipline Laboratory of Wide Band Gap Semiconductor Technology School of MicroelectronicsXidian UniversityXi'an 710071China

High qualityβ-Ga_(2)O_(3)single crystal nanobelts with length of 2−3 mm and width from tens of microns to 132μm were synthesized by carbothermal reduction *** on the grown nanobelt with the length of 600μm,the dual-Schottky-junctions coupling device(DSCD)was *** to the electrically floating Ga_(2)O_(3)nanobelt region coupling with the double Schottky-junctions,the current I_(S2)increases firstly and rapidly reaches into saturation as increase the voltage V_(S2).The saturation current is about 10 pA,which is two orders of magnitude lower than that of a single *** the case of solar-blind ultraviolet(UV)light irradiation,the photogenerated electrons further aggravate the coupling physical mechanism in device.I_(S2)increases as the intensity of UV light *** the UV light of 1820μW/cm^(2),I_(S2)quickly enters the saturation *** V_(S2)=10 V,photo-to-dark current ratio(PDCR)of the device reaches more than 104,the external quantum efficiency(EQE)is 1.6×10^(3)%,and the detectivity(D*)is 7.5×10^(12)*** addition,the device has a very short rise and decay times of 25−54 ms under different positive and negative *** shows unique electrical and optical control characteristics,which will open a new way for the application of nanobelt-based devices.

关键词： β-Ga_(2)O_(3)nanobelt carbothermal reduction UV light dual-Schottky coupling device

AB_(2)-type rare earth-based compounds with C-15 structure:Looking for reversible hydrogen storage materials

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Journal of Rare Earths 2024年第5期42卷 803-816,I0001页

作者： Hao Shen Junxian Zhang Valerie Paul-Boncour Ping Li Zhinian Li Yuanfang wu lijun Jiang National Engineering Research Center of Nonferrous Metals Materias and Products for New Energy GRINM Group Co.LtdBeijing00088China Univ Paris Est Creteil CNRSICMPEUMR 71822 rue Henri Dunant94320ThiaisFrance Institute for Advanced Materials and Technology University of Science and TechnologyBeijing100083China GRIMAT Engineering Institute Co. Ltd.Beijing101407China

AB_(2)-type(A=rare earth,B=transition metal)intermetallic compounds with C15 structure can easily absorb large amount of hydrogen,showing their potential use as hydrogen storage *** crucial problem hindering their application is hydrogen induced amorphization(HIA),which leads to the irreversible hydrogen sorption *** stability of the AB_2 Laves phase compounds,the structural properties,the hydrogenation properties and the controlling factors of HIA are discussed in this *** with other factors,the atomic radii ratio r_A/r_B is the most important one influencing the ***-element substitution is an efficient way to suppress or limit HIA and may enable AB_2 compounds to be suitable for hydrogen storage.

关键词： Rare earth-based AB_2-type compounds Hydrogenation properties Hydrogen induced amorphization Elemental substitution

N6-methyladenosine facilitates mitochondrial fusion of colorectal cancer cells via induction of GSH synthesis and stabilization of OPA1 mRNA

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National Science Review 2024年第3期11卷 72-91页

作者： Jiawang Zhou Haisheng Zhang Ke Zhong lijun Tao Yu Lin Guoyou Xie Yonghuang Tan You wu Yunqing lu Zhuojia Chen Jiexin Li Xin Deng Qin Peng Zigang Li Hongsheng Wang Guangdong Provincial Key Laboratory of New Drug Design and Evaluation School of Pharmaceutical Sciences Sun Yat-sen University Sun Yat-sen University Cancer Center State Key Laboratory of Oncology in South China and Collaborative Innovation Center for Cancer Medicine Department of Biomedical Sciences City University of Hong Kong Institute of Systems and Physical Biology Shenzhen Bay Laboratory

Mitochondria undergo fission and fusion that are critical for cell survival and cancer development, while the regulatory factors for mitochondrial dynamics remain elusive. Herein we found that RNA m6A accelerated mitochondria fusion of colorectal cancer（CRC） cells. Metabolomics analysis and function studies indicated that m6A triggered the generation of glutathione（GSH） via the upregulation of RRM2B——a p53-inducible ribonucleotide reductase subunit with anti-reactive oxygen species potential. This in turn resulted in the mitochondria fusion of CRC cells. Mechanistically, m6A methylation of A1240 at 3 UTR of RRM2B increased its m RNA stability via binding with IGF2BP2. Similarly, m6A methylation of A2212 at the coding sequence（CDS） of OPA1——an essential GTPase protein for mitochondrial inner membrane fusion——also increased m RNA stability and triggered mitochondria fusion. Targeting m6A through the methyltransferase inhibitor STM2457 or the dm6ACRISPR system significantly suppressed mitochondria fusion. In vivo and clinical data confirmed the positive roles of the m6A/mitochondrial dynamics in tumor growth and CRC progression. Collectively, m6A promoted mitochondria fusion via induction of GSH synthesis and OPA1 expression, which facilitated cancer cell growth and CRC development.

关键词： m6A mitochondrial fusion glutathione OPA1 colorectal cancer

Embedded Scenario Clustering for Wind and Photovoltaic Power,and Load Based on Multi-head Self-attention

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Protection and Control of Modern Power Systems 2024年第1期9卷 122-132页

作者： lijun Liu Xin Hu Junsheng Chen Ruixing wu Feixiong Chen School of Electrical Engineering and Automation Fuzhou UniversityFuzhou 350108China State Grid Fuzhou Power Supply Company Fujian Smart Electrical Engineering Technology Research Center

The source and load uncertainties arising from increased applications of renewable energy sources such as wind and photovoltaic energy in the power system have had adverse effects on optimal planning and *** for generating typical renewable energy and load scenarios are constructed to reduce such effects and improve the applicability of a planning and optimal dispatching model of power systems with a high proportion of renewable *** traditional clustering-based model for representing such scenarios cannot handle high-dimensional time-series data and consequently the feature-related information obtained cannot fully reflect the characteristics of the ***,a deep convolutional embedded clustering model based on multi-head self-attention is ***,a variational mode decomposition model is optimized to reduce the influence of noise-related signals on the feature *** deep features are then extracted from the data using an improved convolutional autoencoder,and the appropriate number of clusters is determined using the elbow *** this,the network parameters are optimized based on the sum of losses during reconstruction and ***,typical scenarios are then generated based on the optimized network ***,the proposed method is evaluated based on data visualization and evaluation *** is shown that the quality of features and the accuracy of clustering can be effectively improved by the proposed scenario generation method.

关键词： handle Embedded network

Correlation of Oral Microbiota With Different Immune Responses to Antiretroviral Therapy in People Living With HIV

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Infectious Microbes & Diseases 2024年第2期6卷 85-92页

作者： Jingying Pan Xiaodi Zhang Danrong Shi Xuebin Tian lijun Xu Xiangyun lu Mingqing Dong Peng Yao Zhaoyi Pan Nanping wu Hangping Yao State Key Laboratory for Diagnosis and Treatment of Infectious Diseases National Clinical Research Center for Infectious DiseasesCollaborative Innovation Center for Diagnosis and Treatment of Infectious DiseasesThe First Affiliated HospitalSchool of MedicineZhejiang UniversityHangzhouChina Department of Infectious Disease Zhejiang Qingchun HospitalZhejiang UniversityHangzhouChina Jinan Microecological Biomedicine Shandong Laboratory JinanChina

Both HIV infection and antiretroviral therapy(ART)affect the oral *** successful treatment with ART in people living with HIV(PLWH),which leads to a significant decline in viral loads and immune reconstitution,is associated with changes in or recovery of the oral microbiome remains ***,we performed a cross-sectional study of 118 PLWH receiving regular ART and 40 healthy controls(HCs).Among the 118 PLWH,18 immunological nonresponders(INRs;lus were more abundant in the IR *** genera Rothia and Alloprevotella were negatively and positively associated with CD4^(+)T cell counts,***,an increased abundance of Rothia in the oral microbiome is associated with unfavorable outcomes regarding immune reconstitution in PLWH receiving regular ART,whereas Prevotella,Alloprevotella,Porphyromonas and Haemophilus are associated with favorable outcomes.

关键词： HIV oral microbiome antiretroviral therapy immunological nonresponders immunological responders

PFOA/PFOS Facilitated Intestinal Fatty Acid Absorption by Activating the PPARαPathway:Insights from Organoids Model

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Environment & Health 2024年第2期2卷 85-94页

作者： Wen Zhang Yushan Tian Biao Chen Shengmin Xu lijun wu Information Materials and Intelligent Sensing Laboratory of Anhui Province Institutes of Physical Science and Information TechnologyAnhui UniversityHefeiAnhui 230601China China National Tobacco Quality Supervision and Test Center ZhengzhouHenan 450001China

Perfluorooctanoic acid(PFOA)and perfluorooctanesulfonate(PFOS)continue to be extensively present in the natural environment and seriously threaten human *** intestinal tract is the primary organ of PFOA/PFOS exposure due to the consumption of contaminated food and drinking ***,it remains unclear how PFOA/PFOS affects intestinal function and overall *** aim of this study was to investigate the influence of PFOA/PFOS on the absorption of fatty acids in the intestine and the underlying mechanisms using three-dimensional(3D)intestinal *** results showed that PFOS,but not PFOA,could significantly enhance the fatty acid uptake capacity without obvious damage to the ***,PFOS markedly reduced the protein levels of ChgA in enteroendocrine cells,but with no observed impact on aldolase B+***,exposure to PFOS induced the activation of the peroxisome proliferator-activated receptor(PPAR)αpathway in intestinal organoids,with enhanced expression of PPARαtarget genes associated with fatty acid metabolism,such as Fabp1 and Cd36(fatty acid transporter genes),Acox1 and Pdk4(fatty acid oxidation genes),and Plin2 and Plin3(lipid droplet synthesis genes).These data suggest that PFOS have the potential to affect the absorption function of the intestinal epithelium through the PPARαpathway,and its effect is much stronger than that of *** findings also highlight that organoids can be used as a valuable model for conducting toxicological research on environmental chemicals.

关键词： PFOA PFOS intestinal organoids fatty acid absorption enteroendocrine cells PPARα