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The modulatory effect of oolong tea polyphenols on intestinal flora and hypothalamus gene expression in a circadian rhythm disturbance mouse model

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Food Science and Human Wellness 2024年第2期13卷 748-764页

作者： Ruonan Yan chi-Tang Ho Yanan Liu Shengnan Zhan Zufang wu Xin Zhang Department of Food Science and Engineering Ningbo UniversityNingbo 315211China Department of Food Science Rutgers UniversityNew BrunswickNew Jersey 08901USA

The interaction between host circadian rhythm and gut microbes through the gut-brain axis provides new clues for tea polyphenols to improve host *** present research showed that oolong tea polyphenols(OTP)improved the structural disorder of the intestinal flora caused by continuous darkness,thereby modulating the production of metabolites related to pyruvate metabolism,glycolysis/gluconeogenesis,and tryptophan metabolism to alleviate the steady-state *** fecal microbiota transplantation from the OTP group,the single-cell transcriptomic analysis revealed that OTP significantly increased the number of hypothalamus cell clusters,up-regulated the number of astrocytes and fibroblasts,and enhanced the expression of circadian rhythm genes Cry2,Per3,Bhlhe41,Nr1d1,Nr1d2,Dbp and Rorb in hypothalamic *** results confirmed that OTP can actively improve the intestinal environmental state as well as internal/peripheral circadian rhythm disorders and cognitive impairment,with potential prebiotic functional characteristics to notably contribute to host health.

关键词： Gut microbiota Circadian rhythm Oolong tea polyphenols Single-cell sequencing Metabolism

54例孕妇超前分娩镇痛的有效性和安全性观察

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广东医科大学学报 2024年第1期42卷 86-88页

作者：颜振艺陈晓凤莫坚陈昊王永燕吴驰广东医科大学附属医院广东湛江524000 广东医科大学附属第二医院广东湛江524001

目的观察超前镇痛用于孕妇超前分娩镇痛的有效性和安全性。方法 108例孕妇随机分为对照组和超前镇痛组,每组54例。对照组:采用硬膜外注入罗哌卡因+舒芬太尼混合液进行自控麻醉镇痛(PCEA)。超前镇痛组:孕妇即将进入临产、未规律宫缩前泵... 详细信息

目的观察超前镇痛用于孕妇超前分娩镇痛的有效性和安全性。方法 108例孕妇随机分为对照组和超前镇痛组,每组54例。对照组:采用硬膜外注入罗哌卡因+舒芬太尼混合液进行自控麻醉镇痛(PCEA)。超前镇痛组:孕妇即将进入临产、未规律宫缩前泵入1 mL/h镇痛药(包括1.2 g/L罗哌卡因、0.4 mg/L舒芬太尼),进入规律宫缩后进行PCEA。比较两组镇痛效果、麻醉药物用量、分娩方式、孕妇满意度以及不良反应。结果超前镇痛组的镇痛有效率、孕妇满意度均明显高于对照组,剖宫产率低于对照组(P0.05)。结论超前镇痛用于分娩镇痛可以有效提高镇痛效果和孕妇满意度,降低剖宫产率。

关键词：超前镇痛分娩镇痛罗哌卡因舒芬太尼

The clinical features and meningeal histochemistry of meningeal malignant melanosis

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chinese Medical Journal 2008年第23期121卷 2458-2460页

作者： LIU Xue-wu chi Zhao-fu ZHAO Xiu-he wu Wei Department of Neurology Qilu Hospital of Shandong University Jinan Shandong 250012 China

Meningeal malignant melanosis is a meninges tumor that can produce melanin. Primary intracranial neurocutaneous melanosis is rare. It grows fast with a high degree of malignancy and is associated with earlier intracranial hypertension and meningeal irritation. Most of them can not be diagnosed unless by biopsy or autopsy1. lntracranial malignant melanosis is divided into two kinds： primary and secondary which transfers through the lymph or blood. We report one case of meningeal malignant melanosis that was confirmed by meningeal pathology.

关键词： melanosis cerebrospinal fluid pathology

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氟吡菌酰胺对非靶标生物的急性毒性效应

现代农药 2024年第1期23卷 65-69页

作者：吴迟李敏刘新刚崔少青孙田何明远中国农业科学院植物保护研究所植物病虫害生物学国家重点实验室北京100193 广西思浦林科技有限公司南宁530001

探究了氟吡菌酰胺对8种非靶标生物的急性毒性,以明确氟吡菌酰胺对环境生物的毒性风险。结果表明,氟吡菌酰胺对鸟、蜜蜂、家蚕、蚯蚓和鱼的毒性等级均为低毒,对赤眼蜂属于低风险,对水生生物大型溞和藻类的毒性等级均为中等毒。因此,在田... 详细信息

探究了氟吡菌酰胺对8种非靶标生物的急性毒性,以明确氟吡菌酰胺对环境生物的毒性风险。结果表明,氟吡菌酰胺对鸟、蜜蜂、家蚕、蚯蚓和鱼的毒性等级均为低毒,对赤眼蜂属于低风险,对水生生物大型溞和藻类的毒性等级均为中等毒。因此,在田间施用氟吡菌酰胺时,应注意对水生生物的保护,使用时远离水产养殖区,避免在水体中清洗施药用具。

关键词：氟吡菌酰胺非靶标生物急性毒性

Clinical Study on Puncturing Houxi (SI 3) Toward Hegu (LI 4) plus Lumbar Movement for Acute Lumbar Sprain

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Journal of Acupuncture and Tuina Science 2013年第1期11卷 53-56页

作者： Zhou Jing-hui wu Yao-chi SunYi-jun Zhang Jun-feng Hong Jue Department of Acupuncture Tuina and TraumatologyNo.6 People's Hospital Affiliated to Shanghai Jiaotong University Department of Acupuncture Tuina and TraumatologyNo.6 People’s Hospital Affiliated to Shanghai Jiaotong University

Objective： To observe the therapeutic efficacy of puncturing Houxi （SI 3） toward Hegu （LI 4） plus lumbar movement in treating acute lumbar sprain. Methods： A total of 212 patients with acute lumbar sprain were randomized into two groups. There were 106 subjects in the observation group who were treated with puncturing Houxi （SI 3） toward Hegu （LI 4） plus lumbar movement; the other 106 patients in the control group were treated with puncturing Houxi （SI 3） toward Hegu （LI 4） alone. Therapeutic efficacy was evaluated after 2 treatment courses. Results： The total effective rate was 95.3% in the observation group versus 88.7% in the control group, and the difference was statistically insignificant between the two groups （P〉O.05）. However, in comparing the treatment times for achieving recovery and effectiveness, differences between the two groups were statistically significant （both P〈O.05）, indicating that integrated use of acupuncture and exercise is faster in realizing therapeutic effectiveness. Conclusion： By selecting fewer acupoints, puncturing Houxi （Sl 3） toward Hegu （LI 4） is effective in treating acute lumbar sprain, and with the help of lumbar movement, it can achieve even better treatment effect.

关键词： Point-through-point Method Acupuncture Therapy Electroacupuncture Low Back Pain Lumbar Sprain Sprains and Strains

Leaching kinetics and permeability of polyethyleneimine added ammonium sulfate on weathered crust elution-deposited rare earth ores

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Journal of Rare Earths 2024年第8期42卷 1610-1619,I0008页

作者： Huifang Yang Aoyang Sha Zhengyan He Chenjie wu Yuanlai Xu Jingjing Hu Zhigao Xu Ru'an chi Key Laboratory for Green Chemical Process of Ministry of Education School of Resources&Safety EngineeringWuhan Institute of TechnologyWuhan 430073China Key Laboratory of Resources Conversion and Pollution Control of the State Ethnic Affairs Commission College of Resources and Environmental ScienceSouth-Central MinzuUniversityWuhan430074China

At present,in-situ leaching of weathered crust elution-deposited rare earth ores(WCE-DREOs) encounter with problems such as long leaching cycles,slow infiltration rate and low product *** order to solve the above problems,the conventional leaching agent ammonium sulfate((NH_(4))_(2)SO_(4)) was compounded with polymeric surfactant polyethyleneimine(PEI) to form a composite leaching *** effects of leaching temperature,PEI *** rate and pH on leaching kinetics and permeability of rare earths(RE) and aluminum(AI) in orebody were *** is found that with temperature increasing,the time required to reach leaching equilibrium for both RE and Al is shortened,the apparent activation energies of RE and AI are 14.79 and 13.45 kJ/mol,respectively,and the leaching processes are in accordance with the outer diffusion control,When the concentrations of(NH_(4))_(2)SO_(4) and PEI in the composite leaching agent are 2.0 wt% and 0.4 wt%;the time required to reach leaching equilibrium for RE and AI is about 50% shorter than that using(NH_(4))_(2)SO_(4) alone,and the leaching efficiencies of RE are slightly higher than that of *** increasing the temperature and flow rate of the composite leaching agent can improve the leaching efficiencies of RE and Al,but pH has neglected effects on the leaching efficiencies of *** PEI concentrations below 0,4 wt%, the addition of PEI promotes the leaching of RE and *** column leaching studies of the WCE-DREO,the addition of 0.4 wt% PEI to the traditional leaching agent(NH_(4))_(2)SO_(4) has no impact on the leaching efficiencies of ***,it can significantly increase the infiltration rate of WCE-DREO,shortening the leaching time per 10 mL effluent from about 30 min for(NH_(4))_(2)SO_(4) leaching system to 20 min for the composite leaching *** leaching time is shortened by one-third,and the leaching cost is reduced,which can provide theoretical guidance for the development and commercial implementa

关键词： Polyethyleneimine Kinetics Rare earths Permeability Activation energy

NOVEL SYNTHESIS OF LONG MULTI-BLOCK HETEROPOLYMER CHAINS WITH AN ORDERED SEQUENCE AND CONTROLLABLE BLOCK LENGTHS

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chinese Journal of Polymer Science 2001年第5期19卷 451-454页

作者： chi wu Zuo-wei Xie Guang-zhao Zhang Guo-fu Zi Department of Chemistry, The chinese University of Hong Kong Shatin, N.T., Hong Kong china 香港中文大学香港

It had very long been a dream in polymer science to synthesize long multi-block polymer chains with an orderedchain sequence and controllable block lengths. Using ionic or living free radical polymerization or furnishing each end ofpolymer blocks with a reactive functional group, one can only prepare heteropolymer chains with few long blocks, such asdiblock and triblock copolymers. The most plausible result so far was a pentablock copolymer. Recently, using a combinationof polymer physics and synthetic chemistry, we have invented self-assembly assisted polycondensation (SAAP). Thiscommunication reports the results of using this novel. method to connect 10-100 triblock polymer chains together to formlong multi-block heteropolymer chains with an ordered sequence and controllable block lengths.

关键词： multi-block copolymer self assembly self assembly assisted polypolymerization novel polymer synthesis

Enclosed Extent of the Saline Water and its Constraints on the Sedimentary and Salt Forming Characteristics:A Case Study of the Paleogene Playas in Hoh Xil Basin

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Acta Geologica Sinica(English Edition) 2014年第S1期88卷 320-322页

作者： GONG Daxing YI Haisheng ZHOU Jiayun wu chi Hua Xia Guoqing Institute of Multipurpose Utilization of Mineral Resources Chinese Academy of Geological Sciences Chengdu University of Techology

1 Introduction There is a long period of hot,arid climates in the Jurassic-Neogene,in the eastern of the Neo-Tethys where is been called Western Yunnan—Qiangtang tectonic belt(Zheng et al.,2010).Especially in the Paleogene,under the control of the planetary winds and the north subtropical high pressure belts,a ribbon arid,semi-arid

关键词： Enclosed extent Paleogene playas sedimentary and salt forming characteristics Hoh Xil Basin

高分子线性柔性链在超滤过程中第一类突变现象的观察

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高分子学报 2005年第4期15卷 486-490页

作者：金帆吴奇香港中文大学化学系中国香港新界沙田

利用一种双层结构的膜屏蔽了每个微孔所产生的流场之间的相互作用,从而首次观测到理论上预计的高分子线性柔性链在超滤过程中的第一类突变现象,即仅当宏观流速高于一宏观阈值时,高分子长链方可通过尺寸远小于链无扰半径的微孔,且该宏观... 详细信息

利用一种双层结构的膜屏蔽了每个微孔所产生的流场之间的相互作用,从而首次观测到理论上预计的高分子线性柔性链在超滤过程中的第一类突变现象,即仅当宏观流速高于一宏观阈值时,高分子长链方可通过尺寸远小于链无扰半径的微孔,且该宏观阈值与高分子链的长短无关.另外,实验中的过滤膜含有多个微孔,实验结果显示,当一给定的宏观流速低于宏观阈值时,部分微孔会被无法通过的较长的高分子链堵塞,造成未堵塞微孔中的微观流速大于微观阈值.因此,较短的高分子链可从未堵塞的微孔通过滤膜.

关键词：高分子超滤微孔滤膜第一类突变激光光散射高分子线性柔性链高分子链突变现象超滤过程第一类长链