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black hole shadows in Einstein-bel-Robinson gravity

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chinese Physics c 2024年第5期48卷 272-283页

作者： b.Hamil b.c.Lütfüoğlu Laboratoire de Physique Mathématique et Subatomique Facultédes Sciences ExactesUniversitéConstantine 1ConstantineAlgeria Department of Physics University of Hradec KrálovéRokitanského 6250003 Hradec KrálovéCzechia

Gravity models given by higher-order scalar curvature corrections are believed to bear important consequences. Einstein-bel-Robinson (EbR) gravity with quartic curvature modification motivated Sajadi et al. to explore static spherically symmetric.b.ack hole solutions using perturbative methods. In this study, inspired by their work, we investigate AdS black hole shadows in EbR gravity and demonstrate how the gravity parameter alters the energy emission rate. Finally, we address the same problem in the presence of plasma, because the black holes are thought to be surrounded by a medium that changes the geodesic of photons.

关键词： black hole shadows Einstein-bel-Robinson gravity plasma

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Lipocoacervate,a tunable vesicle for protein delivery

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Nano Research 2024年第10期17卷 9135-9140页

作者： chia-Wei Yeh Nathaniel wright chelsea Loh Nabeen chu Yadong Wang Nancy E.and Peter c.Meinig School of biomedical Engineering Cornell UniversityKimball Hall 290Ithaca 14853USA Human biology Healthand Society.College of Human EcologyCornell UniversityIthaca 14853USA

controlled delivery of proteins and other biologics is a growing medium of therapy for diseases previously *** we report a self-assembling,tunable vesicle for the controlled delivery of growth factors and *** made of heparin and a biocompatible polycation,PEAD,forms the core of the vesicle;lipids form the membrane of the *** call this vesicle lipocoacervate(Lipco),which has a high affinity for growth factors and cytokines due to *** is a tunable protein delivery *** vesicle size is controlled through polymer and salt *** functionalization enables potential for targeting capabilities with long-term storage through ***,the controlled delivery of therapeutics also avoids high toxicity to treated cells in *** we report on these key principles of Lipco assembly and design.

关键词： complex coacervate drug delivery protein delivery heparin lipid particle

Semi-analytical investigation of heat transfer in a porous convective radiative moving longitudinal fin exposed to magnetic field in the presence of a shape-dependent trihybrid nanofluid

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Applied Mathematics and Mechanics(English Edition) 2024年第1期45卷 197-216页

作者： c.G.PAVITHRA b.J.GIREESHA M.L.KEERTHI Department of PG Studies and Research in Mathematics Kuvempu UniversityShankaraghatta 577451India Department of Mathematics and Statistics M.S.Ramaiah University of Applied SciencesBengaluru 560058India

The thermal examination of a non-integer-ordered mobile fin with a magnetism in the presence of a trihybrid nanofluid(Fe_3O_4-Au-Zn-blood) is carried out. Three types of nanoparticles, each having a different shape, are considered. These shapes include spherical(Fe_3O_4), cylindrical(Au), and platelet(Zn) configurations. The combination approach is utilized to evaluate the physical and thermal characteristics of the trihybrid and hybrid nanofluids, excluding the thermal conductivity and dynamic viscosity. These two properties are inferred by means of the interpolation method based on the volume fraction of nanoparticles. The governing equation is transformed into a dimensionless form, and the Adomian decomposition Sumudu transform method(ADSTM) is adopted to solve the conundrum of a moving fin immersed in a trihybrid nanofluid. The obtained results agree well with those numerical simulation results, indicating that this research is reliable. The influence of diverse factors on the thermal overview for varying noninteger values of γ is analyzed and presented in graphical representations. Furthermore, the fluctuations in the heat transfer concerning the pertinent parameters are studied. The results show that the heat flux in the presence of the combination of spherical, cylindrical, and platelet nanoparticles is higher than that in the presence of the combination of only spherical and cylindrical nanoparticles. The temperature at the fin tip increases by 0.705 759% when the value of the Peclet number increases by 400%, while decreases by 11.825 13% when the value of the Hartman number increases by 400%.

关键词： convection radiation moving longitudinal fin Adomian decomposition Sumudu transform method(ADSTM) trihybrid nanofluid magnetic field

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Urotensin-I suppresses the hypothalamo-hypophyseal-ovarian axis in the Mozambique tilapia,Oreochromis mossambicus

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Aquaculture and Fisheries 2024年第3期9卷 339-346页

作者： Jyoti A.Kumbar c.b.Ganesh Neuroendocrinology Research Laboratory Department of Studies in ZoologyKarnatak UniversityDharwad580003India

Urotensin-I(UI)is a peptide belonging to the corticotropin-releasing hormone family,produced in the urophysis of *** investigation was undertaken to examine the effect of UI on the hypothalamo-hypophyseal-ovarian axis in the Mozambique tilapia,a cichlid *** the first experiment,administration of UI(2μg/100μL saline)for 22 days caused a significant reduction in the number of follicles at stages I,II,III(previtellogenic),IV(vitellogenic),and V(preovulatory),concomitant with a significant increase in the percent atresia of follicles at stages II,III,and IV than in *** the pituitary,gonadotropin-releasing hormone(GnRH)-positive fibres were detected in the proximal pars distalis(PPD)in both controls and UI-treated fish;however,there was a significant reduction in the intensity and percent area of GnRH-immunoreactive fibres in fish treated with UI compared with *** serum luteinizing hormone(LH)level was significantly lower,whereas a significant rise in the serum level of cortisol was noticed in UI-treated fish compared with *** the second experiment,treatment with a low dose of UI(10 mM)did not affect the number of AcTH-secreting cells in vitro,but the number of these cells was significantly higher in high-dose UI(50 mM)-treated pituitaries compared to ***,the present investigation reveals for the first time that the treatment of UI affects the follicular development process through the downregulation of the GnRH-LH axis and activation of the pituitary-interrenal pathway in teleosts.

关键词： Urotensin-I cRH family Gonadotropin-releasing hormone Luteinizing hormone Ovary Oreochromis mossambicus

cYP3A5 unexpectedly regulates glucose metabolism through the AKT-TXNIP-GLUT1 axis in pancreatic cancer

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Genes & Diseases 2024年第4期11卷 381-399页

作者： Ming Shao Qingfei Pan Haiyan Tan Jing Wu Ha Won Lee Andrew D.Huber William c.wright Ji-Hoon cho Jiyang Yu Junmin Peng Taosheng chen Department of chemical biology and Therapeutics St.Jude Children's Research HospitalMemphisTN 38105USA Department of computational biology St.Jude Children's Research HospitalMemphisTN 38105USA center for Proteomics and Metabolomics St.Jude Children's Research HospitalMemphisTN 38105USA Department of Structural biology St.Jude Children's Research HospitalMemphisTN 38105USA Department of Developmental Neurobiology St.Jude Children's Research HospitalMemphisTN 38105USA

cYP3A5 is a cytochrome P450(cYP)enzyme that metabolizes drugs and contributes to drug resistance in ***,it remains unclear whether cYP3A5 directly influences cancer *** this report,we demonstrate that cYP3A5 regulates glucose metabolism in pancreatic ductal ***-omics analysis showed that cYP3A5 knockdown re-sults in a decrease in various glucose-related metabolites through its effect on glucose trans-port.A mechanistic study revealed that cYP3A5 enriches the glucose transporter GLUT1 at the plasma membrane by restricting the translation of TXNIP,a negative regulator of ***,cYP3A5-generated reactive oxygen species were proved to be responsible for atten-uating the AKT-4EbP1-TXNIP signaling ***3A5 contributes to cell migration by maintaining high glucose uptake in pancreatic *** together,our results,for the first time,reveal a role of cYP3A5 in glucose metabolism in pancreatic ductal adenocarcinoma and identify a novel mechanism that is a potential therapeutic target.

关键词： cell migration cYP3A5 Glucose metabolism GLUT1 Pancreatic cancer TXNIP

The role of extracorporeal life support and timing of repair in infants with congenital diaphragmatic hernia

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World Journal of Pediatric Surgery 2024年第2期7卷 90-99页

作者： Daniel b Gehle Logan c Meyer Tim Jancelewicz Le bonheur children's Hospital University of Tennessee Health Science CenterMemphisTennesseeUSA

Extracorporeal life support(EcLS)serves as a rescue therapy for patients with congenital diaphragmatic hernia(cDH)and severe cardiopulmonary failure,and only half of these patients survive to *** costly intervention has a significant complication risk and is reserved for patients with the most severe disease physiology refractory to maximal cardiopulmonary *** contraindications to EcLS do exist such as coagulopathy,lethal chromosomal or congenital anomaly,very preterm birth,or very low birth weight,but many of these limits are being evaluated through further *** guidelines from the past decade vary in recommendations for EcLS use in patients with cDH but this therapy appears to have a survival benefit in the most severe subset of *** outcomes have been observed for patients treated at high-volume *** review details the evolving literature surrounding management paradigms for timing of cDH repair for patients receiving preoperative *** recent data support early repair following cannulation to avoid non-repair which is uniformly fatal in this *** EcLS runs are associated with decreased survival,and patient physiology should guide EcLS weaning and eventual decannulation rather than limiting patients to arbitrary run *** of care across centers is a major focus to limit unnecessary costs and improve short-term and long-term outcomes for these complex patients.

关键词： congenital life repair

Efficient guiding and focusing of intense laser pulse using periodic thin slits

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Matter and Radiation at Extremes 2024年第4期9卷 29-39页

作者： L.Xu T.W.Huang K.Jiang c.N.Wu H.Peng P.c.hen R.Li H.b.Zhuo c.T.Zhou Shenzhen Key Laboratory of Ultraintense Laser and Advanced Material Technology Center for Intense Laser ApplicationTechnologyand College of Engineering PhysicsShenzhen Technology UniversityShenzhen 518118People’s Republic of China

Slits have been widely used in laser-plasma interactions as plasma optical components for generating high-harmonic light and controlling laser-driven particle ***,we propose and demonstrate that periodic thin slits can be regarded as a new breed of optical elements for efficient focusing and guiding of intense laser *** fundamental physics of intense laser interaction with thin slits is studied,and it is revealed that relativistic effects can lead to enhanced laser focusing far beyond the pure diffractive focusing *** addition,the interaction of an intense laser pulse with periodic thin slits makes it feasible to achieve multifold enhancement in both laser intensity and energy transfer efficiency compared with conventional *** results provide a novel method for manipulating ultra-intense laser pulses and should be of interest for many laser-based applications.

关键词： laser pulse intense

Rescattering of stimulated Raman side scattering in nonuniform plasmas

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Matter and Radiation at Extremes 2024年第5期9卷 68-76页

作者： S.Tan Q.Wang Y.chen W.b.Yao c.Z.Xiao J.F.Myatt School of Physics and Electronics Hunan UniversityChangsha 410082China Institute of Applied Physics and computational Mathematics Beijing 100094China School of Electrical and Information Engineering Anhui University of Science and TechnologyHuainanAnhui 232001China Department of Electrical and computer Engineering University of Alberta9211116 St.NWEdmontonAlberta T6G 1H9Canada

Rescattering of stimulated Raman side scattering(SRSS)is observed for the first time via two-dimensional(2D)particle-in-cell(PIc)*** construct a theoretical model for the rescattering process,which can predict the region of occurrence of mth-order SRSS and estimate its *** rescattering process is identified by the 2D PIc simulations under typical conditions of a direct-drive inertial confinement fusion *** electrons produced by second-order SRSS propagate nearly perpendicular to the density gradient and gain nearly the same energy as in first-order SRSS,but there is no cascade acceleration to produce superhot *** studies for a wide range of ignition conditions show that SRSS and associated rescatterings are robust and important processes in inertial confinement fusion.

关键词： nonuniform acceleration scattering

Exploring one material for dual applications:A red-emitting Mg2GeO4:Eu3+ nanophosphor for future generation energy efficient WLEDs and dosimetric applications

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Journal of Rare Earths 2024年第10期42卷 1835-1845页

作者： Akshay Arjun G.P.Darshan S.c.Sharma H.Nagabhushana D.V.Sunitha H.b.Premkumar Department of Physics Faculty of Mathematical and Physical SciencesM.S.Ramaiah University of Applied Sciences Jain University c.N.R.Rao centre for Advanced Materials Tumkur University School of Applied Sciences (Physics) REVA University

The envisaged design and developme nt of individual mate rials to excavate a broader spectrum of desired properties and offer multiple applications are highly *** this in mind,a series of forsterite-structured Mg2GeO4:Eu3+（1 mol%-9 mol%） nanophosphors was synthesized via a solution combustion method using oxalyl dihydrazide as a *** X-ray diffraction patterns confirm the orthorhombic crystal system with a Puma space *** results clearly show irregularly shaped cluster-like structures with aggregation of the *** diffuse reflectance spectra,the optical energy band gap of the Mg2GeO4:Eu3+（1 mol%-9 mol%） nanophosphors was estimated and obtained to be～4.12-4.32 *** photoluminescence emission spectra exhibit intense peaks at ～579,589,610,661,and 707 nm,which are due to characteristic5D0→7F0,5D0→7F1,5Do→7F2,5D0→7F3and5D0→7F4transitions of Eu3+ions,*** commission International de L'Eclairage color coordinates are gradually tuned from pale red（0.5980,0.4012） to a pure red（0.6385,0.3611） *** glow peaks showcase excellent super-linear response at low doses of γ-irradiations,indicating that the prepared phosphor can be used in thermoluminescent personal dosimetry which is a biological tissue *** aforementioned results demonstrate that the prepared Mg2GeO4:Eu3+（1 mol%-9 mol%） nanophosphors are considered an excellent candidate for dual applications,i.e.,red component in future generation white-light-emitting diodes（WLEDs） and personal dosimetric applications.

关键词： Dosimetry Nanophosphors Photoluminescence Photometric properties Rare earths Thermoluminescence