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Ventricular fibrillation and sudden cardiac arrest in apical hypertrophic cardiomyopathy:Two case reports

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World Journal of Clinical Cases 2021年第35期9卷 11102-11107页

作者： Yae Min Park Albert Youngwoo Jang wook-jin chung Seung Hwan Han Christopher Semsarian In Suck Choi Department ofCardiology Gachon University Gil Medical CenterIncheon 21556South Korea Agnes Ginges Centre for Molecular Cardiology Centenary Institute The University of SydneySydney 21556Australia

BACKGROUND Apical hypertrophic cardiomyopathy(HCM)is considered to have a benign prognosis in terms of cardiovascular *** serial case report aimed to raise awareness of ventricular fibrillation(VF)and sudden cardiac death(SCD)in apical *** SUMMARY Here we describe two rare cases of apical HCM that presented with documented VF and sudden cardiac *** patients were previously not recommended for primary prevention using implantable cardioverter-defibrillator(ICD)therapy based on current ***,both received ICD therapy for the secondary prevention of *** These cases illustrate serious complications including VF and aborted sudden cardiac arrest in apical HCM patients who are initially not candidates for primary prevention using ICD implantation based on current guidelines.

关键词： Apical hypertrophic cardiomyopathy Ventricular fibrillation Implantable cardioverter-defibrillator Case report

硅负载离子液体的合成、表征以及其催化甲酸和三乙基胺作为氢源的环己酮还原胺化反应（英文）

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催化学报 2015年第8期36卷 1365-1371页

作者： Ashif H.Tamboli Avinash A.Chaugule Faheem A.Sheikh wook-jin chung Hern Kim Department of Energy Science and Technology Energy and Environment Fusion Technology CenterMyongji University

A silica supported ionic liquid was synthesized and characterized by scanning electron microscopy(SEM), Fourier transform infrared spectroscopy, X-ray diffraction, N2 adsorption-desorption, and thermogravimetric analysis. All these techniques, especially SEM results indicated the presence of well-defined spherical particles having diameters larger than the pristine silica particles, confirming the successful immobilization of the ionic liquid. The prepared silica supported ionic liquid was used in the reductive amination of cyclohexanone under different conditions with different azeotropic mixtures of formic acid and triethyl amine as a hydrogen source. The catalyst showed efficient catalytic performance and excellent yields of N-cyclohexyl amine derivatives in the range of 58% to 84% at 30 °C. After completion of the reaction, the catalyst was easily recovered by simple filtration and reused for another five cycles without any significant impact on product yields. The obtained catalytic performance indicates that the present catalyst is green, very active, and reusable for the reductive amination of cyclohexanone.

关键词：离子液体催化剂还原胺化硅胶负载环己酮三乙胺合成氢源甲酸

Defect Detection Model Using Time Series Data Augmentation and Transformation

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Computers, Materials & Continua 2024年第2期78卷 1713-1730页

作者： Gyu-Il Kim Hyun Yoo Han-jin Cho Kyungyong chung Department of Computer Science Kyonggi UniversitySuwon-si16227Korea Contents Convergence Software Research Institue Kyonggi UniversitySuwon-si16227Korea Department of Energy IT Engineering Far East UniversityEumsung-gun27601Korea Division of AI Computer Science and Engineering Kyonggi UniversitySuwon-si16227Korea

Time-series data provide important information in many fields,and their processing and analysis have been the focus of much ***,detecting anomalies is very difficult due to data imbalance,temporal dependence,and ***,methodologies for data augmentation and conversion of time series data into images for analysis have been *** paper proposes a fault detection model that uses time series data augmentation and transformation to address the problems of data imbalance,temporal dependence,and robustness to *** method of data augmentation is set as the addition of *** involves adding Gaussian noise,with the noise level set to 0.002,to maximize the generalization performance of the *** addition,we use the Markov Transition Field(MTF)method to effectively visualize the dynamic transitions of the data while converting the time series data into *** enables the identification of patterns in time series data and assists in capturing the sequential dependencies of the *** anomaly detection,the PatchCore model is applied to show excellent performance,and the detected anomaly areas are represented as heat *** allows for the detection of anomalies,and by applying an anomaly map to the original image,it is possible to capture the areas where anomalies *** performance evaluation shows that both F1-score and Accuracy are high when time series data is converted to ***,when processed as images rather than as time series data,there was a significant reduction in both the size of the data and the training *** proposed method can provide an important springboard for research in the field of anomaly detection using time series ***,it helps solve problems such as analyzing complex patterns in data lightweight.

关键词： Defect detection time series deep learning data augmentation data transformation

Fabrication of La,Ce co-doped ZnO nanorods for improving photodegradation of methylene blue

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Journal of Rare Earths 2024年第1期42卷 76-83,I0003页

作者： Erfan Hakim Azmal Zaid jin-chung Sin Sze-Mun Lam Abdul Rahman Mohamed School of Chemical Engineering Universiti Sains Malaysia(USM)14300Nibong TebalPenangMalaysia College of Environmental Science and Engineering Guilin University of TechnologyGuilin541004China Guangxi Key Laboratory of Theory and Technology for Environmental Pollution Control Guilin University of TechnologyGuilin541004China Collaborative Innovation Center for Water Pollution Control and Water Safety in Karst Area Guilin University of TechnologyGuilin541004China Faculty of Engineering and Green Technology Universiti Tunku Abdul RahmanJalan UniversitiBandar Barat31900KamparPerakMalaysia

La,Ce co-doped ZnO nanorods(ZnLC)were synthesized through a one-step solvothermal *** photocatalysts were characterized by X-ray diffraction,Raman spectroscopy,field-emission scanning electron microscopy,energy dispersive X-ray,transmission electron microscopy,UV-vis diffuse reflectance spectroscopy and photo luminescence *** La and Ce doping enhanced the visible light absorption ability of ZnLC and a red shift was detected for *** simulated solar light irradiation,the ZnO doped with 3 at%La and 1 at%Ce(ZnLC1)degrades methylene blue(MB)more effectively than those of pure ZnO,La-doped ZnO(ZnL)and commercially available *** improved photocatalytic performance of ZnLC1 can be attributed to the high charge separation efficiency as demonstrated by the photoluminescence ***,the photocatalytic experiments reveal that several parameters have their own impact on the MB *** a variety of radical scavengers,it is discovered that superoxide anion radical plays a crucial role in the degradation of *** ZnLC1 is also reused several times without noticeable decrease of photoactivity,indicating that it has a substantial potential for environmental remediation applications.

关键词： ZnO Lanthanum Cerium Co-doping Photodegradation Rare earths

Highly Aligned Ternary Nanofiber Matrices Loaded with MXene Expedite Regeneration of Volumetric Muscle Loss

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Nano-Micro Letters 2024年第4期16卷 269-292页

作者： Moon Sung Kang Yeuni Yu Rowoon Park Hye jin Heo Seok Hyun Lee Suck Won Hong Yun Hak Kim Dong‑wook Han Department of Cogno‑Mechatronics Engineering College of Nanoscience and NanotechnologyPusan National UniversityBusan 46241Republic of Korea Medical Research Institute School of MedicinePusan National UniversityYangsan 50612Republic of Korea Department of Anatomy School of MedicinePusan National UniversityYangsan 50612Republic of Korea Engineering Research Center for Color‑Modulated Extra‑Sensory Perception Technology Pusan National UniversityBusan 46241Republic of Korea Department of Biomedical Informatics School of MedicinePusan National UniversityYangsan 50612Republic of Korea Periodontal Disease Signaling Network Research Center and Dental and Life Science Institute School of DentistryPusan National UniversityYangsan 50612Republic of Korea BIO‑IT Fusion Technology Research Institute Pusan National UniversityBusan 46241Republic of Korea Present Address:Osstem Implant Inc. Seoul 07789Republic of Korea

Current therapeutic approaches for volumetric muscle loss(VML)face challenges due to limited graft availability and insufficient *** overcome these limitations,tissue-engineered scaffolds have emerged as a promising *** this study,we developed aligned ternary nanofibrous matrices comprised of poly(lactide-co-ε-caprolactone)integrated with collagen and Ti_(3)C_(2)T_(x)MXene nanoparticles(NPs)(PCM matrices),and explored their myogenic potential for skeletal muscle tissue *** PCM matrices demonstrated favorable physicochemical properties,including structural uniformity,alignment,microporosity,and *** vitro assays revealed that the PCM matrices promoted cellular behaviors and myogenic differentiation of C2C12 ***,in vivo experiments demonstrated enhanced muscle remodeling and recovery in mice treated with PCM matrices following VML *** insights from next-generation sequencing revealed that MXene NPs facilitated protein and ion availability within PCM matrices,leading to elevated intracellular Ca^(2+)levels in myoblasts through the activation of inducible nitric oxide synthase(i NOS)and serum/glucocorticoid regulated kinase 1(SGK1),ultimately promoting myogenic differentiation via the m TOR-AKT ***,upregulated i NOS and increased NO–contributed to myoblast proliferation and fiber fusion,thereby facilitating overall myoblast *** findings underscore the potential of MXene NPs loaded within highly aligned matrices as therapeutic agents to promote skeletal muscle tissue recovery.

关键词： Ti_(3)C_(2)T_(x)MXene nanoparticle Ternary nanofibrous matrices Myogenesis Regeneration of volumetric muscle loss Next generation sequencing

Transparent high-performance piezoceramics through pressureless sintering

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Journal of Advanced Ceramics 2024年第5期13卷 561-567页

作者： Hye-Lim Yu Woo-Seok Kang Ju-Hyeon Lee Temesgen Tadeyos Zate Young-jin Lee Bo-Kun Koo Dong-jin Shin Min-Soo Kim Soon-Jong Jeong Young Ghyu Ahn wook Jo Department of Material Science and Engineering Ulsan National Institute of Science and TechnologyUlsan 44919Republic of Korea Energy Conversion Research Center Korea Electrotechnology Research InstituteChangwon 51543Republic of Korea MLCC Development Team Component Biz.UnitSamsung Electro-Mechanics Co.Ltd.Suwon 16674Republic of Korea

Piezoelectricity offers an electromechanical coupling that is widely utilized in transducer *** has been a consistent demand for transparent piezoelectric materials for optoelectrical ***,despite the inherent tradeoff between the transparency and the piezoelectricity,numerous strategies have been explored to develop the transparent piezoelectric ***,the most transparent piezoelectric materials developed to date is either a single crystal or materials that achieve transparency via hot-press sintering,limiting its industrial ***,we introduce a novel piezoelectric material that ensures transparency through co-doping and pressureless sintering of polycrystalline *** this study,we employed a compositional optimization approach to enhance the synergistic effect between the transparency and the piezoelectric properties of 0.71Pb(Mg_(1/3)Nb_(2/3))O_(3)–0.29PbTiO_(3)(PMN–0.29PT)*** utilizing the tape casting process for mass production and large-area manufacturing,our Pb_(0.913)La_(0.0145)Sm_(0.0145)(Mg_(1/3)Nb_(2/3))_(0.71)Ti_(0.29)O_(3)(TP2.9)ceramics exhibited over 60%transparency and large piezoelectric coefficient(d33)of 1104 pC/*** material holds considerable promise for a wide range of industrial applications in both the optical and electronic domains.

关键词： piezoelectric ceramics transparency pressureless sintering co-doping tape casting

Crystallographically vacancy‐induced MOF nanosheet as rational single‐atom support for accelerating CO_(2)electroreduction to CO

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Carbon Energy 2024年第8期6卷 49-62页

作者： jin Hyuk Cho Joonhee Ma Chaehyeon Lee jin wook Lim Youngho Kim Ho Yeon Jang Jaehyun Kim Myung‐gi Seo Youngheon Choi Youn Jeong Jang Sang Hyun Ahn Ho Won Jang Seoin Back Jong‐Lam Lee Soo Young Kim Department of Materials Science and Engineering Korea UniversitySeoulRepublic of Korea Department of Chemical and Biomolecular Engineering Sogang UniversitySeoulRepublic of Korea Department of Materials Science and Engineering Pohang University of Science and Technology(POSTECH)PohangRepublic of Korea Department of Materials Science and Engineering Research Institute of Advanced MaterialsSeoul National UniversitySeoulRepublic of Korea Lotte Chemical R&D Center DaejeonRepublic of Korea Department of Chemical Engineering Hanyang UniversitySeoulRepublic of Korea School of Chemical Engineering and Material Science Chung‐Ang UniversitySeoulRepublic of Korea

To attain a circular carbon economy and resolve CO_(2)electroreduction technology obstacles,single‐atom catalysts(SACs)have emerged as a logical option for electrocatalysis because of their extraordinary catalytic *** SACs,metal–organic frameworks(MOFs)have been recognized as promising support materials because of their exceptional ability to prevent metal *** study shows that atomically dispersed Ni single atoms on a precisely engineered MOF nanosheet display a high Faradaic efficiency of approximately 100%for CO formation in H‐cell and three‐compartment microfluidic flow‐cell reactors and an excellent turnover frequency of 23,699 h−1,validating their intrinsic catalytic *** results suggest that crystallographic variations affect the abundant vacancy sites on the MOF nanosheets,which are linked to the evaporation of Zn‐containing organic linkers during ***,using X‐ray absorption spectroscopy and density functional theory calculations,a comprehensive investigation of the unsaturated atomic coordination environments and the underlying mechanism involving CO^(*)preadsorbed sites as initial states was possible and provided valuable insights.

关键词： 2‐dimensional material carbon dioxide reduction metal-organic frameworks single‐atom catalysts vacancy sites

Trifunctional robust electrocatalysts based on 3D Fe/N-doped carbon nanocubes encapsulating Co4N nanoparticles for efficient battery-powered water electrolyzers

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Carbon Energy 2024年第6期6卷 124-139页

作者： Hyung wook Choi Hongdae Lee Jun Lu Seok Bin Kwon Dong In Jeong Beum jin Park Jiwon Kim Bong Kyun Kang Gun Jang Dae Ho Yoon Ho Seok Park SKKU Advanced Institute of Nano Technology(SAINT) Sungkyunkwan UniversitySuwon-siGyeonggi-doRepublic of Korea School of Chemical Engineering Sungkyunkwan UniversitySuwon-siGyeonggi-doRepublic of Korea School of Advanced Materials Science and Engineering Sungkyunkwan UniversitySuwon-siGyeonggi-doRepublic of Korea Department of Electronic Materials Devicesand Equipment EngineeringSoonchunhyang UniversityAsan CityChungnamRepublic of Korea SKKU Institute of Energy Science and Technology(SIEST) Sungkyunkwan UniversitySuwon-siGyeonggi-doRepublic of Korea Department of Health Sciences and Technology Samsung Advanced Institute for Health Sciences and Technology(SAIHST)Sungkyunkwan UniversitySuwonRepublic of Korea

Herein,we have designed a highly active and robust trifunctional electrocatalyst derived from Prussian blue analogs,where Co_(4)N nanoparticles are encapsulated by Fe embedded in N-doped carbon nanocubes to synthesize hierarchically structured Co_(4)N@Fe/N-C for rechargeable zinc-air batteries and overall water-splitting *** confirmed by theoretical and experimental results,the high intrinsic oxygen reduction reaction,oxygen evolution reaction,and hydrogen evolution reaction activities of Co_(4)N@Fe/N-C were attributed to the formation of the heterointerface and the modulated local electronic ***,Co_(4)N@Fe/N-C induced improvement in these trifunctional electrocatalytic activities owing to the hierarchical hollow nanocube structure,uniform distribution of Co_(4)N,and conductive encapsulation by Fe/***,the rechargeable zinc-air battery with Co_(4)N@Fe/N-C delivers a high specific capacity of 789.9 mAh g^(-1) and stable voltage profiles over 500 ***,the overall water electrolyzer with Co_(4)N@Fe/N-C achieved better durability and rate performance than that with the Pt/C and IrO2 catalysts,delivering a high Faradaic efficiency of 96.4%.Along with the great potential of the integrated water electrolyzer powered by a zinc-air battery for practical applications,therefore,the mechanistic understanding and active site identification provide valuable insights into the rational design of advanced multifunctional electrocatalysts for energy storage and conversion.

关键词： battery-powered electrolyzers hierarchical structure Prussian blue analog trifunctional electrocatalyst zinc-air battery

Ten- year follow- up investigation of stroke risk in systemic lupus erythematosus

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Stroke & Vascular Neurology 2024年第1期9卷 1-7页

作者： jin-An Huang Ching-Heng Lin Ming-Ju Wu Yi-Hsing Chen Kuo-Cheng Chang chung-Wei Hou Division of Neurology Neurological InstituteTaichung Veterans General HospitalTaichungTaiwan Department of Health Business Administration Hungkuang UniversityTaichungTaiwan Department of Medical Research Taichung Veterans General HospitalTaichungTaiwan Division of Nephrology Department of Internal MedicineTaichung Veterans General HospitalTaichungTaiwan School of Medicine Chung Shan Medical UniversityTaichungTaiwan College of Medicine National Chung Hsing UniversityTaichungTaiwan Division of Allergy Immunology and RheumatologyDepartment of Internal MedicineTaichung Veterans General HospitalTaichungTaiwan School of Medicine National Yang-Ming Chiao Tung UniversityTaichungTaiwan

Background and purpose To analyse the long-term risk of ischaemic stroke and the clinical effects of antithrombotics on the risk of haemorrhagic stroke in patients with systemic lupus erythematosus(SLE).Methods A retrospective cohort study was conducted using a population-based database taken from Taiwan National Health Insurance Research *** with SLE between 2000 and 2008 were registered and matched with two controls by the index date,age,gender and Charlson Comorbidity Index(CCI).These subjects were followed until either stroke event or 31 December *** HRs(aHRs)for strokes were estimated with Cox regression models,and the cumulative incidence of ischaemic stroke was analysed by log-rank test and Kaplan-Meier survival *** In total,8310 patients with SLE and 16620 patients without SLE were *** general,patients with SLE had higher rates of ischaemic stroke(5.4%vs 3.3%)and haemorrhagic stroke(1.5%vs 0.6%)than in *** multivariate analysis adjusted to age,gender,CCI,urbanisation level and antithrombotics uses,aHRs of all strokes,ischaemic stroke and haemorrhagic stroke were 1.73(95%CI:1.54 to 1.94),1.65(95%CI:1.45 to 1.87)and 2.24(95%CI:1.71 to 2.95),respectively,in patients with *** with SLE were significantly more likely to suffer ischaemic stroke than patients without SLE,even 10 years after SLE diagnosis(6.12%vs 3.50%,p<0.001).Antiplatelet use increased the risk of haemorrhagic stroke in SLE group(aHR=1.74,95%CI:1.18 to 2.57).Conclusions Patients with SLE are at greater risk of developing ischaemic stroke that lasts for 10 *** should be carefully administered to prevent cardiovascular events in patients with SLE due to the risk of haemorrhagic stroke.

关键词： erythematosus diagnosis likely