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Plasma Science and Technology 2020年第10期22卷 135-144页

作者： Junmyung lee Yunho NAM Jongchan lee hyun woo lee Kwang-Ho KWON Department of Control and Instrumentation Engineering Korea UniversitySejong 30019Republic of Korea Department of Aeronautic Computer Engineering Hanseo UniversitySeosan 31962Republic of Korea

Perfluorocarbon gas is widely used in the semiconductor ***,perfluorocarbon has a negative effect on the global environment owing to its high global warming potential(GWP) *** alternative solution is ***,we evaluated the possibility of replacing conventional perfluorocarbon etching gases such as CHF_3 with C_6F_(12)O,which has a low GWP and is in a liquid state at room *** this study,silicon oxynitride(SiON) films were plasma-etched using inductively coupled CF4+C_6F_(12)O+O_2 mixed ***,the etching characteristics of the film,such as etching rate,etching profile,selectivity over Si,and photoresist,were investigated.A double Langmuir probe was used and optical emission spectroscopy was performed for plasma *** addition,a contact angle goniometer and x-ray photoelectron spectroscope were used to confirm the change in the surface properties of the etched SiON film ***,the etching characteristics of the C_6F_(12)O mixed plasma exhibited a lower etching rate,higher SiON/Si selectivity,lower plasma damage,and more vertical etched profiles than the conventional CHF_3 mixed *** addition,the C_6F_(12)O gas can be recovered in the liquid state,thereby decreasing global *** results confirmed that the C_6F_(12)O precursor can sufficiently replace the conventional etching gas.

关键词： global warming potential perfluorocarbon silicon oxynitride etching characteristics liquid-state perfluorocarbon

Improving construction work zone safety using technology:A systematic review of applicable technologies

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Journal of Traffic and Transportation Engineering(English Edition) 2020年第1期7卷 61-75页

作者： Chukwuma Nnaji John Gambatese hyun woo lee Fan Zhang Department of Civil Construction and Environmental EngineeringThe University of AlabamaTuscaloosaAL 35487USA School of Civil and Construction Engineering Oregon State UniversityCoruallisOR 97331USA Department of Construction Management University of WashingtonSeattleWA 98195USA School of Construction and Design University of Southern MississippiHattiesburgMS 39406USA

Once considered conventional,the construction industry is gradually increasing its reliance on innovations such as the application of technologies in safety *** the growing literature on technology applications in safety management and the varying opinions on the utility of applied technologies,a systematic review that streamlines findings from past studies is indispensable to construction *** a number of review studies are available in the building construction sector,the level of fragmentation and uniqueness within the construction industry necessitates a review study specifically targeting the heavy civil *** response,the present study applies a three-step approach to identify and review articles pertinent to the safety of highway construction work *** factors considered include the number of publications per year,publication locations,and technology *** addition,the present study proposes to broadly group work zone safety technologies(WZSTs)into three categories based on their primary purpose:speed reduction systems,intrusion prevention and warning systems,and human-machine-interaction detection *** findings include WZST research trends,application of smart work zone systems,and the potential relationship between WZSTs and *** paper ends with the identification of six additional research areas aimed at deepening the understanding of technology’s role in highway safety *** trend analysis and an in-depth discussion of each technology category alongside the identified research gaps will provide a substantial informative body of knowledge that both benefits current practitioners and directs researchers towards potential future studies.

关键词： Transportation Work zone Worker safety Technology application Safety technology Systematic review

Diagnostic performance of the current risk-stratified approach with computed tomography for suspected choledocholithiasis and its options when negative finding

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Hepatobiliary & Pancreatic Diseases International 2019年第4期18卷 366-372页

作者： hyun woo lee Tae Jun Song Do hyun Park Sang Soo lee Dong-Wan Seo Sung Koo lee Myung-Hwan Kim Jae Hyuck Jun Ji Eun Moon Yeon Han Song Digestive Disease Center and Research Institute Department of Internal MedicineSoonchunhyang University School of MedicineBucheonKorea Division of Gastroenterology Department of Internal MedicineUniversity of Ulsan College of MedicineAsan Medical CenterSeoulKorea Division of Gastroenterology Department of Internal MedicineUniversity of Eulji College of MedicineEulji Medical CenterDaejeonKorea Department of Biostatistics Clinical trial centerSoonchunhyang University Bucheon HospitalBucheonKorea

Background:Several studies evaluated the current guideline of the American Society for Gastrointestinal Endoscopy(ASGE)and reported only suboptimal *** study evaluated the diagnostic performance of the ASGE guideline based on computed tomography(CT)and role of endoscopic ultrasonography(EUS)and magnetic resonance cholangiopancreatography(MRCP)in patients with suspected choledocholithiasis but negative CT ***:Patients with suspected choledocholithiasis undergoing ERCP between January 2016 and January 2017 were retrospectively *** patients underwent CT to detect *** or MRCP was performed when the CT scan showed negative *** were classified into the high and intermediate-risk groups,based on predictors from the ASGE ***:Of 583 patients with suspected choledocholithiasis,340(58.3%)had stones on ERCP(65.9%in the high-risk group and 40.6%in the intermediate-risk group).The accuracy of ASGE guideline for CT was 63.98%(79.12%sensitivity,42.80%specificity)and 36.02%(20.88%sensitivity,57.20%specificity)in the high-risk and intermediate-risk groups,*** 103 patients in the high-risk group underwent both CT and US,the accuracy of CT was higher than that of US for detecting choledocholithiasis(78.64%vs.53.40%),with a significant difference in area under the curve(AUC)(0.78 vs.0.59,P<0.001).Of 339 with negative CT finding,the accuracy of EUS was higher than that of MRCP(90.91%vs.82.76%),but with no significant difference in AUC(0.91 vs.0.83,P=0.347).Conclusions:CT-based ASGE guideline showed superior diagnostic performance than US for predicting *** diagnostic options,EUS or MRCP,with negative CT finding showed comparable ***,the diagnostic modality should be selected based on availability,experience,cost,and contraindications.

关键词： Choledocholithiasis ASGE guideline Accuracy Endoscopic ultrasound Magnetic resonance cholangiopancreatography

Two distinct subpopulations of marginal zone B cells exhibit differential antibody-producing capacities and radioresistance

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Cellular & Molecular Immunology 2024年第4期21卷 393-408页

作者： Sujin lee Yeunjung Ko hyun woo lee Won Joon Oh Hun Gi Hong Dinuka Ariyaratne Se Jin Im Tae Jin Kim Department of Immunology Graduate School of Basic Medical ScienceSungkyunkwan University School of MedicineSuwon16419Republic of Korea Department of Immunology and Molecular Medicine Faculty of Medical SciencesUniversity of Sri JayewardenepuraNugegodaSri Lanka Present address:Immunology and Microbiology Graduate Program Baylor College of MedicineHoustonTX77030USA

Marginal zone(MZ)B cells,which are splenic innate-like B cells that rapidly secrete antibodies(Abs)against blood-borne pathogens,are composed of heterogeneous ***,we showed that MZ B cells can be divided into two distinct subpopulations according to their CD80 expression ***80^(high)MZ B cells exhibited greater Ab-producing,proliferative,and IL-10-secreting capacities than did CD80^(low)MZ B ***,CD80^(high)MZ B cells survived 2-Gy whole-body irradiation,whereas CD80^(low)MZ B cells were depleted by irradiation and then repleted with one month after *** of CD80^(low)MZ B cells led to accelerated development of type II collagen(CII)-induced arthritis upon immunization with bovine ***80^(high)MZ B cells exhibited higher expression of genes involved in proliferation,plasma cell differentiation,and the antioxidant ***80^(high)MZ B cells expressed more autoreactive B cell receptors(BCRs)that recognized double-stranded DNA or CII,expressed more immunoglobulin heavy chain sequences with shorter complementarity-determining region 3 sequences,and included more clonotypes with no N-nucleotides or with B-1a BCR sequences than CD80^(low)MZ B *** transfer experiments showed that CD21^(+)CD23^(+)transitional 2 MZ precursors preferentially generated CD80^(low)MZ B cells and that a proportion of CD80^(low)MZ B cells were converted into CD80^(high)MZ B cells;in contrast,CD80^(high)MZ B cells stably remained CD80^(high)MZ B *** summary,MZ B cells can be divided into two subpopulations according to their CD80 expression levels,Ab-producing capacity,radioresistance,and autoreactivity,and these findings may suggest a hierarchical composition of MZ B cells with differential stability and BCR specificity.

关键词： Marginal Zone B Cell CD80 Autoreactivity Radioresistance

Game Selection Method for Game-Based History Learning

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Journal of Contemporary Educational Research 2021年第10期5卷 67-81页

作者： woo-hyun lee Won-hyung lee Chung-Ang University 84 Heukseok-ro Dongjak-gu 06974Korea

Games that are used in research on game-based learning and serious games that are used for education are usually exclusive,making it difficult for teachers to attempt new methods in *** to the data published in 2009 by the European Schoolnet(EUN),a network of European Ministries of Education,most of the problems that teachers face when using games in class are related to game *** on the aforementioned data,this study presents a set of criteria for selecting games in order to solve the inconvenience experienced by *** games,which are used as teaching materials for game-based learning,have been replaced with commercial games that are easily purchased,rather than serious games that are difficult to obtain the *** on the criteria,two games were selected in this study and the classes were conducted at the educational *** to the group trained with textbooks,it has been confirmed that the effect of game-based learning was *** addition,five out of ten problems that teachers face were resolved.

关键词： Game-based learning History education Commercial game Reenactment of history learning

An Effective Control Report Based Security Countermeasure against the Joint Attacks of False Report Injection Attack and Selective Forwarding Attack

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Wireless Sensor Network 2012年第8期4卷 185-190页

作者： hyun woo lee Tae Ho Cho College of Information and Communication Engineering Sungkyunkwan University Suwon Korea

Sensor networks are vulnerable to many attacks because the sensor networks operate in open environments. It is easy to incur one or more attacks such as a selective forwarding attack, a false report injection attack. It is hard to defend the sensor network from the multiple attacks through existing security methods. Thus, we suggest an energy-efficient security method in order to detect the multiple attacks. This paper presents a security method to detect the false report injection attack and the selective forwarding attack in the sensor network using a new message type. The message type is a filtering message. The filtering message prevents from generating and forwarding false alert messages. We evaluated performance of our proposed method through a simulation in comparison with an application of SEF (statistical enroute filtering scheme) and CHEMAS (Check point-based Multi-hop Acknowledgement Scheme). The simulation results represent that the proposed method is 10% more energy-efficient than the application when the number of false reports is great while retaining the detection performance.

关键词： False Report Injection Attack Selective Forwarding Attack SEF CHEMAS

Probability Control for Verification of an Event Report Using Fuzzy System

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Wireless Sensor Network 2011年第12期3卷 371-377页

作者： hyun woo lee Soo Young Moon Tae Ho Cho 不详

Sensor networks include numerous sensor nodes that are vulnerable to physical attacks from the outside because they operate in open environments. The sensor nodes are compromised by an attacker. The compromised nodes generate false reports and inject the reports into sensor networks. The false report injection attacks deplete energy of the sensor nodes. Ye et al. proposed Statistical En-Route Filtering (SEF) to defend sensor nodes against the false report injection attacks. In SEF, sensor nodes verify the event reports based on a fixed probability. Thus, the verification energy of a node is the same whether the report is false or valid. But when there are few false reports, energy for verifying legitimate reports may be wasted. In this paper, we propose a method in which each node controls a probability of attempts at verification of an event report to reduce the wasted energy. The probability is determined through consideration of the number of neighboring nodes, the number of hops from the node to the sink node, and the rate of false reports among the 10 most recent event reports forwarded to a node. We simulated our proposed method to prove its energy efficiency. After the simulation, we confirmed that the proposed method is more efficient than SEF for saving sensor node’s energy.

关键词： Sensor Network Statistical En-Route Filtering False Report Injection Attack

Attenuated FOLFIRINOX in the salvage treatment of gemcitabine-refractory advanced pancreatic cancer: a phase II study

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Cancer Communications 2018年第1期38卷 344-351页

作者： Jung Hoon Kim Sang-Cheol lee Sung Yong Oh Seo-Young Song Namsu lee Eun Mi Nam Soonil lee In Gyu Hwang Hyo Rak lee Kyu Taek lee Sang-Byung Bae Han Jo Kim Joung Soon Jang Do Hyoung Lim hyun woo lee Seok Yun Kang Jung Hun Kang Department of Internal Medicine Institute of Health SciencesGyeongsang National University15 Jinju-daero 816beon-gilJinju 52727Republic of Korea Divsion of Hematology and Oncology Department of Internal MedicineSoonchunhyang University Hospital CheonanCheonan 31151Republic of Korea Department of Internal Medicine Dong-A University HospitalBusan 49201Republic of Korea Department of Internal Medicine Kangwon National University School of MedicineChuncheon 24289Republic of Korea Divsion of Hematology and Oncology Department of Internal MedicineSoonchunhyang University Hospital SeoulSeoul 04401Republic of Korea Department of Internal Medicine Ewha Womans UniversityCollege of MedicineSeoul 07985Republic of Korea Department of Internal Medicine Dankook University HospitalCheonan 31116Republic of Korea Department of Internal Medicine Chung-Ang UniversityCollege of MedicineSeoul 06973Republic of Korea Division of Hematology and Medical Oncology Department of Internal MedicineKorea Cancer HospitalSeoul 01812Republic of Korea Department of Hematology-Oncology Ajou University HospitalSuwon 16499Republic of Korea

Background:Combination therapy with oxaliplatin,irinotecan,fluorouracil,and leucovorin(FOLFIRINOX)chemotherapy drastically improves survival of advanced pancreatic cancer ***,the efficacy of FOLFIRINOX as a second-line treatment after gemcitabine failure has not been tested *** investigated the feasibility and safety of attenuated FOLFIRINOX in patients with gemcitabine-refractory advanced pancreatic ***:A multicenter phase II prospective open-label,single-arm study was conducted at 14 *** with histologically proven invasive ductal pancreatic adenocarcinoma,a measurable or evaluable lesion,Eastern Cooperative Oncology Group performance status 0 or 1,adequate organ function,and aged 19 years or older were *** FOLFIRINOX consisted of oxaliplatin 65 mg/m2,irinotecan 135 mg/m2,and leucovorin 400 mg/m2 injected intravenously on day 1 and 5-fluorouracil 2000 mg/m2 continuously infused intravenously over 46 h on days 1-2,repeated every 2 *** primary endpoint was progression-free survival from the initiation of *** endpoints were the objective response rate,disease control rate,overall survival,safety,and *** estimated overall survival and progression-free survival using the Kaplan-Meier ***:We enrolled 39 patients from 14 *** objective response rate was 10.3%,while the disease control rate was 64.1%.The 6-month and 1-year overall survival rates were 59.0%and 15.4%,*** progression-free survival and overall survival were 3.8 months(95%confidence interval[CI]1.5-6.0 months)and 8.5 months(95%CI 5.6-11.4 months),*** 3 or 4 adverse events were neutropenia(41.0%),nausea(10.3%),anorexia(10.3%),anemia(7.7%),mucositis(7.7%),pneumonia/pleural effusion(5.1%),and fatigue(5.1%).One treatment-related death attributable to septic shock ***:Attenuated FOLFIRINOX may be promising as a second-line therapy for gemcitabin

关键词： Attenuated FOLFIRINOX Second-line Pancreatic cancer Gemcitabine

A Switched-Capacitor Lossless Inductor ZCS Snubber-Assisted Series Load Resonant High Frequency Inverter with Dual Mode Pulse Modulation Scheme

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A Switched-Capacitor Lossless Inductor ZCS Snubber-Assisted ...

An Asymmetrical Switched Capacitor and Lossless Inductor Quasi-Resonant Snubber-Assisted ZCS-PWM DC-DC Converter with High frequency Link

CES/IEEE 5th International Power Electronics and Motion Control Conference

作者： Khairy Fathy Takaaki Okude Hideki Omori hyun woo lee Mutsuo Nakaoka Kyungnam University Masan Korea Matsushita Electric Industrial Co.Ltd. Osaka Japan Matsushita Electric Industrial Co.Ltd. Osaka Japan Kyungnam University Masan Korea Kyungnam University Masan Korea Industrial College of TechnologyHyogoJapan

＜正＞In this paper, a novel type auxiliary active edge resonant snubber assisted zero current soft switching pulse modulation series load resonant inverter using IGBT power modules is proposed for cost effective consumer high-frequency induction heating （IH） appliances. Its operating principle in steady state is described by using each switching mode equivalent operating circuits. The new multi resonant high-frequency inverter with series load resonance and edge resonance can regulate its high frequency output power under a condition of a constant frequency zero current soft switching （ZCS） commutation principle on the basis of asymmetrical pulse width modulation （PWM） control scheme. The consumer brand-new IH products using proposed ZCS-PWM high-frequency inverter is evaluated and discussed as compared with conventional type inverter on the basis of experimental results. In order to extend ZCS operation ranges under a low power setting PWM as well as to improve efficiency, the high frequency pulse density modulation （PDM） strategy is demonstrated for high frequency multi resonant inverter. Its practical effectiveness is substantially proved from an application point of view.

关键词： Auxiliary switched capacitor snubber Consumer IH appliances Dual mode PWM and PDM control Lossless inductor snubbers Zero current soft switching.

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An Asymmetrical Switched Capacitor and Lossless Inductor Qua...