检索结果-南通市图书馆

Light(Science & Applications) 2019年第1期8卷 766-775页

作者： Jing-Xiang Zhang Wai-Lun Chan Chen Xie Yan Zhou Ho-fai Chau Partha Maity George T.Harrison Aram Amassian Omar F.Mohammed Peter A.Tanner Wai-Kwok wong Ka-Leung wong Department of Chemistry Hong Kong Baptist UniversityKowloon TongHong Kong S.A.R.China Hanshan Normal University ChaozhouGuangdong ProvinceChina Department of Biology Hong Kong Baptist UniversityKowloon TongHong Kong S.A.R.China KAUST Solar Center Division of Physical Science and EngineeringKing Abdullah University of Science and Technology(KAUST)Thuwal 23955-6900Saudi Arabia

Although lanthanide double-decker complexes with hetero-macrocyclic ligands as functional luminescent and magnetic materials have promising properties,their inferior water solubility has negated their biomedical ***,four water-soluble homoleptic lanthanide(Ln=Gd,Er,Yb and La)sandwiches with diethylene-glycoldisubstituted porphyrins(DD)are reported,with their structures proven by both quantum chemical calculations and scanning tunneling *** findings demonstrate that the near-infrared emission intensity and singlet oxygen(1O2)quantum yields of YbDD and GdDD in aqueous media are higher than those of the reported capped lanthanide monoporphyrinato analogues,YbN and GdN;the brightness and luminescence lifetime in water of YbDD are greater than those of *** work provides a new dimension for the future design and development of molecular theranostics-based water-soluble double-decker lanthanide bisporphyrinates.

关键词： lanthanide porphyrin complexes

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

静电相互作用有助于蛋白质的热稳定性

静电相互作用有助于蛋白质的热稳定性

中国晶体学会第四届全国会员代表大会暨学术会议

作者： kam-Bo wong Department of Biochemistry The Chinese University of Hong Kong

＜正＞It has been long assumed that protein is stabilized mainly by the hydrophobic interaction among core residues,while the surface *** interactions contribute little to protein *** we use a ribosomal protein L30e from Thermococcus celer as a model to investigate the electrostatic contributions to protein *** of *** L30e determined by both NMR spectroscopy and X-ray crystallography reveals that the thermophilic homologue has more charge-charge ***-directed mutagenesis studies demonstrated that charge-charge interactions contribute to the thermostability of T.

关键词：

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

曼彻斯特城市更生——曼城水系的再利用

城市建筑 2005年第3期2卷 76-80页

作者：戴锦辉英国AEDAS建筑设计事务所

本文从城市规划与城市设计的角度介绍了曼彻斯特的城市更生,并选取了三个具有代表性的区域加以说明。通过阐述水系的再利用,分析了历史建筑的保护、改扩建和重建在城市改造中的实践意义以及其点、线、面的发展策略。

关键词：城市更生建筑保护改扩建运河再利用

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

高层建筑外围护系统设计浅析

城市建筑 2008年第10期5卷 20-22页

作者：戴锦辉荷兰大都会建筑事务所 oma北京100022

本文以中央电视台新址办公楼外围护系统的设计与建造为切入点,从建筑与环境的关系、外围护与建筑本质的关系、外围护技术与构造三个不同角度探讨我国高层建筑外围护系统设计。

关键词：高层建筑外围护幕墙物理环境人文环境建筑本质

金、银、铜等典型高反射率材料的激光增材制造

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

中国科学：物理学、力学、天文学 2020年第3期50卷 40-53页

作者：顾瑞楠 wong kam Sing 严明南方科技大学材料科学与工程系深圳市高机能材料增材制造重点实验室深圳518055 香港科技大学物理系香港999077

激光增材制造金银材料可用于艺术品、首饰、手表等的定制化制造.铜是传统工业的重要材料,具有良好的导电性和导热性;铜的激光增材制造材料被广泛用于电子设备、热管理系统、交通运输、工业制造等领域.金、银、铜的激光增材制造具有广阔... 详细信息

激光增材制造金银材料可用于艺术品、首饰、手表等的定制化制造.铜是传统工业的重要材料,具有良好的导电性和导热性;铜的激光增材制造材料被广泛用于电子设备、热管理系统、交通运输、工业制造等领域.金、银、铜的激光增材制造具有广阔的应用前景,但也面临着重要问题:金、银、铜材料对激光的吸收率很低.理论分析表明,光吸收率受材料的电导率和激光波长的直接影响.用合金化粉末或表面改性的粉末替代原始粉末打印,或用短波长蓝光或绿光激光打印,可以提高粉体对激光的吸收率,得到更好的打印态样品.本文总结了铜、金等高反射率材料的激光增材制造的激光成型现状和原料端现状,亦对铜、金等高反射率材料的激光增材制造的未来发展趋势做出了展望.

关键词：激光增材制造高反射率金银铜

Probabilistic Models for RFID Detection

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Probabilistic Models for RFID Detection

NOD2 and TLR2 ligands trigger the activation of basophils and eosinophils by interacting with dermal fibroblasts in atopic dermatitis-like skin inflammation

2011 2nd Asia-Pacific Conference on Wearable Computing Systems

作者： Chi-Kong Chan kam-Shing Ng Cho-Tak wong Henry C.B.Chan Department of Computing The Hong Kong Polytechnic University

Radio Frequency Identification（RFID） technology allows items with an RFID tag to be detected effectively and efficiently for identification and other purposes（e.g., for location management and movement detection）. In this paper, we study two probabilistic models, namely a binomial model and a Markov model for RFID detection. These models make use of RFID signals detected by antennas（i.e., RFID detection events）. Based on these models, the detection events can be analyzed or processed to facilitate the development of RFID applications（e.g., integrated RFID gateway and location management）. Our preliminary experimental results show that the models should be effective.

关键词： RFID RFID gateway RFID location management

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

Cellular & Molecular Immunology 2016年第4期13卷 535-550页

作者： Delong Jiao Chun-Kwok wong Huai-Na Qiu Jie Dong Zhe Cai Man Chu kam-Lun Hon Miranda Sin-Man Tsang Christopher Wai-Kei Lam Department of Chemical Pathology The Chinese University of Hong Kong Prince of Wales Hospital Shatin NT Hong Kong China Institute of Chinese Medicine and State Key Laboratory of Phytochemistry and Plant Resources in West China The Chinese University of Hong Kong Hong Kong China Department of Paediatrics The Chinese University of Hong Kong Prince of Wales Hospital Shatin NT Hong Kong China State Key Laboratory of Quality Research in Chinese Medicine Macao institute for Applied Research in Medicine and Health Macao University of Science and Technology Taipa Macao People's Republic of China

The skin of patients with atopic dermatitis （AD） has a unique predisposition for colonization by Staphylococcus aureus （S. aureus）, which contributes to the inflammation and grim prognosis of AD. Although the mechanism underlying the S. aureus-induced exacerbation of AD remains unclear, recent studies have found a pivotal role for pattern recognition receptors in regulating the inflammatory responses in S. aureus infection. In the present study, we used a typical mouse model of AD-like skin inflammation and found that S. aureus-associated nucleotide-binding oligomerization domain-containing protein 2 （NOD2） and toll-like receptor 2 （TLR2） ligands exacerbated AD-like symptoms, which were further deteriorated by the in vivo expansion of basophils and eosinophils. Subsequent histological analyses revealed that dermal fibroblasts were pervasive in the AD-like skin lesions, Co-culture of human dermal fibroblasts with basophils and eosinophils resulted in a vigorous cytokine/chemokine response to the NOD2/TLR2 ligands and the enhanced expression of intercellular adhesion molecule-1 on the dermal fibroblasts. Basophils and eosinophils were primarily responsible for the AD-related cytokine/chemokine expression in the co-cultures. Direct intercellular contact was necessary for the crosstalk between basophils and dermal fibroblasts, while soluble mediators were sufficient to mediate the eosinophil-fibroblast interactions. Moreover, the intracellular p38 mitogen-activated protein kinase, extracellular signal-regulated kinase, and nuclear factor-kappa B signaling pathways were essential for NOD2/TLR2 ligand-mediated activation of basophils, eosinophils, and dermal fibroblasts in AD-related inflammation. This study provides the evidence of NOD2/TLR2-mediated exacerbation of AD through activation of innate immune cells and therefore sheds light on a novel mechanistic pathway bv which S. aureus contributes to the DathoDhvsiology of AD.

关键词： atopic dermatitis basophils, eosinophils NOD2 TLR2

Flexible Implementation of Front-end Acquisition System for Bio-signal using FPAA

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Flexible Implementation of Front-end Acquisition System for ...

Long-Term Treatment with an Herbal Formula MCC Reduces the Weight Gain in High Fat Diet-Induced Obese Mice

2007中国生物医学工程联合学术年会

作者： Chan Wai wong Chan U fai Pun Sio Hang Vai Mang I Mak Peng Un Department of Electrical and Electronics Engineering Faculty of Science and TechnologyUniversity of MacauMacau SARChina Department of Electrical and Electronics Engineering Faculty of Science and TechnologyUniversity of MacauMacau SARChina Department of Electrical and Electronics Engineering Faculty of Science and TechnologyUniversity of MacauMacau SARChina Department of Electrical and Electronics Engineering Faculty of Science and TechnologyUniversity of MacauMacau SARChina Department of Electrical and Electronics Engineering Faculty of Science and TechnologyUniversity of MacauMacau SARChina

＜正＞This paper introduces the implementation principles of a general front-end acquisition system suitable for various bioelectric signals based on FPAA technology and chose the ECG signal as a test-bed for initial verification of our system. The implemented electronic system owns high CMRR characteristics to meet the requirement of bio-signal. The system is tested by a simulated cardiac signal generated from a patient simulator （Metron PS-420）, and ECG signal from a healthy male subject （aged 23）..

关键词： FPAA CMRR ECG Bioelectric Signal

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

Chinese Medicine 2013年第3期4卷 63-71页

作者： Pou Kuan Leong Hoi Yan Leung Hoi Shan wong Jihang Chen Chung Wah Ma Yiting Yang kam Ming Ko Division of Life Science Hong Kong University of Science and Technology Hong Kong China Infinitus (China) Company Ltd. Guangzhou China

Obesity is a risk factor for metabolic disorders, with its prevalence being increased in the world over the past several decades. Therapeutical interventions for obesity are thus urgently needed. In the present study, we investigated the effect of long-term treatment (0.51 and 5.1 g/kg/day, 5 days per week for a total of 40 doses) with an herbal formula MCC [which comprises the fruit of Momordica charantia (MC), the pericarpium of Citri reticulata and L-carnitine] in normal diet (ND) and high fat diet (HFD)-fed female ICR mice. Body weight change was monitored during the course of the experiment. Fat pad indices, plasma glucose and lipid contents, as well as metabolic enzyme activities and mitochondrial coupling efficiency in skeletal muscle were measured at 24 hours after the last dosing. Results showed that HFD increased the body weight, fat pad indices, plasma glucose and lipid contents as well as β-hydroxyacyl-Co A dehydrogenase (β-HAD) and carnitine palmitoyl CoA transferase (CPT) activities in skeletal muscle. However, the phosphofructokinase (PFK) activity was decreased in skeletal muscle. MCC treatment reduced the HFD-induced increases in body weight, fat pad indices and plasma lipid contents. MCC treatment only partially reversed the HFD-induced changes in β-HAD and CPT activities, but did not restore the HFD-induced decrease in PFK activity. MCC did not alter the plasma glucose level and mitochondrial coupling efficiency in skeletal muscle of ND and HFD-fed mice. Since MCC formula did not increase activities of energy metabolic enzymes or induce mitochondrial uncoupling, the weight loss effect of MCC is likely related to the reduction of intestinal lipid absorption in HFD-fed mice.

关键词： Obesity Weight Control Momordica Charantia Citri Reticulata L-Carnitine

Defects properties and vacancy diffusion in Cu_(2)MgSnS_(4)

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Semiconductors 2022年第2期43卷 47-53页

作者： Kin fai Tse Shengyuan Wang Man Hoi wong Junyi Zhu Department of Physics The Chinese University of Hong KongHong KongChina

Cu_(2)Mg_(Sn)S_(4)(CZTS)is a promising photovoltaic absorber material,however,efficiency is largely hindered by potential fluctuation and a band tailing problem due to the abundance of defect complexes and low formation energy of an intrinsic Cu_(Zn)*** to CZTS by group I,II,or IV element replacement to circumvent this challenge has grown research *** this work,using a hybrid(HSE06)functional,we demonstrated the qualitative similarity of defect thermodynamics and electronic properties in Cu_(2)Mg_(Sn)S_(4)(CMTS)to *** show Sn_(Mg)to be abundant when in Sn-and Cu-rich condition,which can be detrimental,while defect properties are largely similar to CZTS in Sn-and *** Sn-and Cu-poor chemic-al potential,there is a general increase in formation energy in most defects except Sn_(Mg),Cu_(Mg)remains as the main contribu-tion to p-type carriers,and Sn_(Mg)may be detrimental because of a deep defect level in the mid gap and the possibility of form-ing defect complex Sn_(Mg)+Mg_(Sn).Vacancy diffusion is studied using generalized gradient approximation,and we find similar va-cancy diffusion properties for Cu vacancy and lower diffusion barrier for Mg vacancy,which may reduce possible Cu-Mg dis-order in *** findings further confirm the feasibility of CMTS as an alternative absorber material to CZTS and suggest the possibility for tuning defect properties of CZTS,which is crucial for high photovoltaic performance.

关键词： CMTS CZTS defect hybrid functional diffusion