检索结果-南通市图书馆

Prolapse gastropathy syndrome may be a predictor of pathologic acid reflux

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2008年第36期14卷 5601-5605页

作者： Jin-Soo Kim Hyung-Keun Kim Young-seok Cho Hiun-Suk Chae Byung-Wook Kim Jin-Il Kim Sok-won Han Kyu-Yong choi Department of Internal Medicine College of Medicine The Catholic University of Korea Uijeongbu St. Mary's Hospital Gyeonggi-do 480-717 South Korea Department of Internal Medicine College of Medicine The Catholic University of Korea Uijeongbu St. Mary’s Hospital Gyeonggi-do 480-717 South Korea Department of Internal Medicine College of Medicine The Catholic University of Korea Our Lady of Mercy Hospital Gyeonggi-do 403-720 South Korea Department of Internal Medicine College of Medicine The Catholic University of Korea Yeoeuido St. Mary’s Hospital Seoul 150-713 South Korea Department of Internal Medicine College of Medicine The Catholic University of Korea Holy Family Hospital Gyeonggi-do 420-717 South Korea

AIM： To assess the occurrence of gastric acid reflux into the esophagus in endoscopically confirmed prolapse gastropathy syndrome （PGS）. METHODS： Using ambulatory esophageal pH measurement （BRAVOTM wireless esophageal pH monitoring system）, twenty-six patients with PGS were compared with twenty-one patients with erosive esophagitis （EE） as controls. We assessed several reflux parameters, including the percentage of total time at pH 〈 4, and the DeMeester score. RESULTS： There were no statistical differences between the PGS group and the EE group as to mean age, sex ratio and pH recording time. The EE group showed more severe reflux than the PGS group, as evaluated in terms of the longest duration of reflux, the number of reflux episodes, the number of reflux episodes lasting 〉 5 min, the total time with pH 〈 4 during acid reflux episodes, and the DeMeester score, but none of these parameters showed statistically significant difference. Although 53.8% （14/26） of the PGS group and 76.2% （16/22） of the EE group demonstrated pathologic acid reflux （DeMeester score 〉 14.72）, there was no statistically significant difference between the two groups in the incidence of pathologic acid reflux （P = 0.11）. CONCLUSION： There was no statistically significant difference in pathologic acid reflux between the PGS and EE group. These data suggest that endoscopically diagnosed PGS might be a predictor of pathologic acid reflux.

关键词： Prolapse gastropathy syndrome Pathologic acid reflux Erosive esophagitis Ambulatory esophageal pH monitoring Retching

Fe-based high-entropy alloy with excellent mechanical properties enabled by nanosized precipitates and heterogeneous grain distribution

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Materials Science & Technology 2024年第14期181卷 71-81页

作者： Heechan Jung Sangwon Lee Taehyeok Kang Alireza Zargaran Pyuck-Pa choi seok Su Sohn Department of Materials Science and Engineering Korea UniversitySeoul 02841Republic of Korea Department of Materials Science and Engineering Korea Advanced Institute of Science and TechnologyDaejeon 34141Republic of Korea Graduate Institute of Ferrous and Energy Materials Technology Pohang University of Science and TechnologyPohang 37673Republic of Korea

High-entropy alloys(HEAs)consisting of CoCrFeNiAlTi systems,with a face-centered cubic(FCC)matrix reinforced by ordered L12 precipitates,have demonstrated exceptional strength-ductility ***,the current compositional design of HEAs heavily relies on high Ni and Co contents,compro-mising the balance between properties and ***,it is crucial to optimize the cost-performance trade-offby fine-tuning the range of Fe,Co,and Ni,while maintaining excellent strength-ductility *** this study,we propose a novel Fe-based HEA with nanosized precipitates and a heteroge-neous grain distribution,achieving a strength-ductility combination comparable to state-of-the-art Ni-or Co-based *** alloy benefits from both precipitation hardening and hetero-deformation-induced strengthening attributed to the heterogeneous grain distribution,resulting in excellent yield strength of 1433 MPa,tensile strength of 1599 MPa,and ductility of 22%.The microstructural evolution and its in-fluence on mechanical properties are unraveled with respect to the observation of precipitate-dislocation interaction and hetero-deformation-induced stress(HDI stress)*** study suggests that the challenge of balancing properties and cost can be addressed through optimized compositional and mi-crostructural design.

关键词： High-entropy alloys Precipitation Heterogeneous microstructure Mechanical property HDI stress

Effects of inter-electrode insertion on the performance and thermal flow fields of a hollow-electrode plasma torch

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Plasma Science and Technology 2020年第1期22卷 33-44页

作者： In-Mok YANG Jun-seok NAM Min-Kyu choi Jun-Ho SEO Shi-Young YANG Department of Applied Plasma Engineering Chonbuk National UniversityJeonju 54896Republic of Korea Graduate School of Flexible&Printable Electronics Chonbuk National UniversityJeonju 54896Republic of Korea

The effects of lntcr-ckxttxxk insertion on the performance of a hollow--electrode plasma torch have been investigated by numerical *** results revealed that when inter-dcctrodes arc inserted,the arc voltages and plasma powers increase due to the increase in the arc *** addition,it was predicted that thermal efficiency can be improved with the increase in plasma power by injecting plasma gases through the gaps between *** unique effects of inter-electrode insertion arc a result of the plasma temperatures adjusting themselves to increase arc voltages when the arc column is contracted radially by increasing gas-flow rate or decreasing inter-electrcxk diameter.

关键词： hollow-electrode plasma torch inter-electrodes numerical analysis torch performance

Endoscopic band ligation and endoscopic hemoclip placement for patients with Mallory-Weiss syndrome and active bleeding

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2008年第13期14卷 2080-2084页

作者： Young-seok Cho Hiun-Suk Chae Hyung-Keun Kim Jin-Soo Kim Byung-Wook Kim Sung-Soo Kim Sok-won Han Kyu-Yong choi Department of Internal Medicine Uijeongbu St. Mary's Hospital The Catholic University of Korea Ujeongbu 480-717 Korea Department of Internal Medicine Our Lady Mercy Hospital The Catholic University of Korea Bupyeong 403720 Korea Department of Internal Medicine Uijeongbu St. Mary’s Hospital The Catholic University of Korea Ujeongbu 480-717 Korea Department of Internal Medicine Holy Family Hospital The Catholic University of Korea Bucheon 420717 Korea

AIM: To compare the hemostatic efficacy and safety of two mechanical endoscopic methods: endoscopic band ligation (EBL) and endoscopic hemoclip placement (EHP) in patients with actively bleeding Mallory-Weiss syndrome (MWS). METHODS: A prospective randomized study to compare the efficacy and safety of EHP with EBL was performed from January 2002 to August 2005. Forty-one patients with active bleeding from MWS were treated with EHP (n = 21) or EBL (n = 20). RESULTS: There were no significant differences between groups with respect to clinical and endoscopic characteristics. The mean number of hemoclips applied was 3.2 ± 1.5 and the mean number of bands applied was 1.2 ± 0.4. Primary hemostasis was achieved in all patients. Recurrent bleeding was observed in one patient from the EHP group and two from the EBL group. Patients with recurrent bleeding were treated by the same modality as at randomization and secondary hemostasis was achieved in all. There were no significant differences between the two groups in total transfusion amount or duration of hospital stay. No complications or bleeding-related death resulted. CONCLUSION: EHP and EBL are equally effective and safe for the management of active bleeding in patients with Mallory-Weiss syndrome, even in those with shock or comorbid diseases.

关键词： Mallory-Weiss syndrome Hemostasis Endoscopic band ligation Endoscopic clipping

Changing trends and characteristics of peptic ulcer disease:A multicenter study from 2010 to 2019 in Korea

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2023年第44期29卷 5882-5893页

作者： Yoon Jin choi Tae Jun Kim Chang seok Bang Yong Kang Lee Moon won Lee Su Youn Nam Woon Geon Shin Seung In Seo Department of Internal Medicine National Cancer CenterGoyang-si 13620South Korea Department of Internal Medicine Samsung Medical CenterSeoul 06351South Korea Department of Internal Medicine Chuncheon Sacred Heart HospitalChuncheon 24253South Korea Department of Internal Medicine National Health Insurance Service Ilsan HospitalGoyang-si 10444South Korea Department of Internal Medicine Pusan National University School of MedicineBusan 50463South Korea Division of Gastroenterology and Hepatology Department of Internal MedicineKyungpook National University Chilgok HospitalDaegu 41404South Korea Department of Internal Medicine Kangdong Sacred Heart HospitalHallym University College of MedicineSeoul 05355South Korea Institute for Liver and Digestive Diseases Hallym UniversityChuncheon 24253South Korea Division of Gastroenterology Department of Internal MedicineKangdong Sacred Heart HospitalSeoul 05355South Korea

BACKGROUND The clinical trend and characteristics of peptic ulcer disease(PUD)have not fully been investigated in the past *** To evaluate the changing trends and characteristics of PUD according to age and METHODS We analyzed seven hospital databases converted into the Observational Medical Outcomes Partnership-Common Data Model between 2010 and *** classified patients with PUD who underwent rapid urease tests or Helicobacter pylori(***)serology into three groups:***-related,drug[nonsteroidal anti-inflammatory drugs(NSAIDs)or aspirin]-related,and idiopathic(***/NSAID/aspirin-negative)PUD and compared the yearly trends and characteristics among the three *** We included 26785 patients in 7 databases,and the proportion of old age(≥65 years)was 38.8%.The overall number of PUD exhibited no decrease,whereas PUD in old age revealed an increasing trend(P=0.01 for trend).Of the 19601 patients,41.8%had ***-related,36.1%had drug-related,and 22.1%had idiopathic *** PUD exhibited a decreasing trend after 2014(P=0.01),drug-related PUD demonstrated an increasing trend(P=0.04),and idiopathic PUD showed an increasing trend in the old-age group(P=0.01)during 10 *** with drug-related PUD had significantly more comorbidities and concomitant ulcerogenic *** idiopathic PUD group had a significantly higher number of patients with chronic liver *** With the aging population increase,the effects of concomitant ulcerogenic drugs and preventive strategies should be investigated in drug-induced *** studies are required to clarify the relationship between idiopathic PUD and chronic liver disease.

关键词： Peptic ulcer disease Drug Idiopathic Trend Characteristics

Cancer stem cell markers CD133 and CD24 correlate with invasiveness and differentiation in colorectal adenocarcinoma

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2009年第18期15卷 2258-2264页

作者： Dongho choi Hyo won Lee Kyung Yul Hur Jae Joon Kim Gyeong-Sin Park Si-Hyong Jang Young Soo Song Ki-seok Jang Seung Sam Paik Department of Surgery College of MedicineSoonchunhyang University140-743 SeoulSouth Korea Department of Surgery Chi Hang Hospital140-741 SeoulSouth Korea Department of Pathology College of MedicineCatholic University137-040 SeoulSouth Korea Department of Pathology College of MedicineHanyang University133-790 SeoulSouth Korea

AIM:To verify that CD markers are available for detecting cancer stem cell populations and to evaluate their clinical significance in colon ***:Immunohistochemistry for CD133,CD24 and CD44 was performed on the tissue microarray of 523 colorectal *** records were reviewed and clinicopathological analysis was ***:In colorectal adenocarcinoma,128 of 523 cases(24.5%) were positive and 395 cases(75.5%) were negative for CD133 *** hundred and sixty-four of 523 cases(50.5%) were positive and 259 cases(49.5%) were negative for CD24 *** hundred and two of 523 cases(96%) were negative and 21 cases(4%) were positive for CD44 *** clinicopathological analysis,CD133 expression was present more in male patients(P = 0.002) and in advanced T stage cancer(P = 0.024).Correlation between CD24 expression and clinicopathological factors was seen in the degree of differentiation(P = 0.006).Correlation between CD44 expression and clinicopathological factors was seen in the tumor size(P = 0.001).Survival was not significantly related to CD133,CD24 and CD44 ***:CD markers were related to invasiveness and differentiation of colorectal ***,CD expression was not closely related to survival.

关键词： CD133 CD24 CD44 Colon cancer stemcells Colorectal adenocarcinoma

Zircon U-Pb ages and O-Hf isotopes of Quaternary trachytes from the East Sea:Implications for the genesis of low-δ^(18)O magmas

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Geoscience Frontiers 2024年第2期15卷 41-54页

作者： Hyun-Ok choi Jihye Oh Chang Hwan Kim Soon Young choi won Hyuck Kim Chan Hong Park Dokdo Research Center East Sea Research InstituteKorea Institute of Ocean Science and TechnologyUljin 36315Republic of Korea Deep-Sea and Seabed Mineral Resources Research Center Korea Institute of Ocean Science and TechnologyBusan 49111Republic of Korea Division of Science Education Kangwon National University1 Gangwondaehak-gilChuncheon-siGangwon-do 24341Republic of Korea

Quaternary intraplate magmatism formed several volcanic islands and seamounts,including Dokdo(DD),Ulleungdo(UD),Simheungtack(ST),Anyongbok,and Isabu in the southwest of the East Sea back-arc *** this study,we present whole-rock geochemical,zircon U–Pb age,and in situ O–Hf isotope data for the submerged volcanic rocks from DD,UD,and ST to provide new insights into the eruption timing of these volcanoes and constrain the magma evolution *** samples used in this study were trachytes and exhibited ferroan,alkalic,and metaluminous to weakly peraluminous *** showed light rare earth element(REE)-enriched patterns with(La/Yb)N ratios of 25.3–31.7 and mostly negative Eu anomalies in a chondrite-normalized REE *** addition,they were enriched in large-ion lithophile elements and high field strength elements;they exhibited positive Pb anomalies and strongly negative Ba,Sr,P,and Ti *** zircons yielded a weighted-mean 206Pb/238U age of 2.61,0.348–0.704,and 2.76–2.94 Ma for the DD,UD,and ST trachytes,*** zircons exhibited lowerδ^(18)O values than normal depleted mantle values,regardless of the crystallization age and spatial distribution of ***δ^(18)O values showed no correlation with U contents or Th/U ratios,indicating that the lowδ^(18)O signatures were of primary magmatic *** Hf isotopic compositions of the zircons were relatively heterogeneous but predominately characterized by positive eHf *** O–Hf mixing modeling revealed that low-δ^(18)O rocks with positive eHf values from the UD and ST volcanoes were derived from a hybrid source of recycled juvenile crustal materials with low-δ^(18)O and positive eHf signatures and an enriched mantle source with normalδ^(18)O and negative eHf *** juvenile oceanic crust in the source was likely metasomatized by seawater at high temperatures prior to *** contrast,the felsic magma that formed the DD volcanoes may have assimilated with regional

关键词： Quaternary intraplate volcanism East Sea Zircon O-Hf isotopes Low-δ^(18)O magma Recycled juvenile oceanic crust

Functions of hepatic non-parenchymal cells in alcoholic liver disease

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Liver Research 2019年第2期3卷 80-87页

作者： won-Mook choi Myung-Ho Kim won-Il Jeong Laboratory of Liver Research Graduate School of Medical Science and EngineeringKorea Advanced Institute of Science and Technology(KAIST)DaejeonRepublic of Korea Department of Gastroenterology Liver CenterAsan Medical CenterUniversity of Ulsan College of MedicineSeoulRepublic of Korea

Alcoholic liver disease(ALD)represents a wide spectrum of disease from simple steatosis to *** there have been multiple attempts to treat ALD,its treatment is still based on abstinence from alcohol and using corticosteroids in specified ***,nearly 40%of patients with ALD who are in need of treatment are unresponsive to the current treatments,which implies a new paradigm shift for the treatment of ***,earlier studies have focused on the abnormal metabolism occurring in the hepatocytes as a protagonist in the pathogenesis of ***,increasing evidence suggests that non-parenchymal cells,such as hepatic stellate cells(HSCs),Kupffer cells,liver sinusoidal endothelial cells,and immune cells around the hepatocytes have critical roles in multiple stages of ALD either by direct or indirect cell-to-cell *** instance,in the early stage of ALD,Kupffer cells and HSCs located closely to hepatocytes contribute to the development of alcoholic steatosis and inflammation through the secretion of various inflammatory cytokines(immunologic pathways)and the activation of the endocannabinoid system(metabolic pathways).While the stage of ALD progresses to alcoholic hepatitis and fibrosis,various cell-to-cell interactions with infiltrating immune cells become highly significant at the multicellular *** review explains the diverse roles of non-parenchymal cells in the progression of ALD,as well as potential therapeutic strategies to treat ALD.

关键词： Alcoholic liver disease(ALD) Hepatic stellate cell(HSC) Immune cell Kupffer cell Natural killer(NK)cell Steatosis Steatohepatitis Fibrosis

Influence of the h TERT rs2736100 polymorphism on telomere length in gastric cancer

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2015年第31期21卷 9328-9336页

作者： Byung Joon choi Jung Hwan Yoon Olga Kim won Suk choi Suk Woo Nam Jung Young Lee won Sang Park Department of Pediatrics College of MedicineThe Catholic University of Korea Department of Pathology College of MedicineThe Catholic University of Korea Functional Rnomics Research Center College of MedicineThe Catholic University of Korea

AIM: To investigate the functional consequences of rs2736100 polymorphism in telomere length and examine its link to gastric cancer ***: Telomere length and human telomerase reverse transcriptase(h TERT) m RNA expression were measured in 35 gastric cancer tissues and 5 cell lines and correlated to rs2736100 polymorphism. The relationship between rs2736100 polymorphism and the risk of gastric cancer were examined in 243 gastric cancer patients and 246 healthy ***: The rs2736100 A allele carrier is closely associated with reduced h TERT m RNA expression and shortened telomere length in gastric cancer tissue and cell lines. When gastric cancers were stratified by histological subtype,telomere length and h TERT m RNA levels were significantly increased in those with the C/C genotype in intestinal-type gastric cancer,but not in diffuse-type gastric cancer. Interestingly,there was no significant difference in the genotype and allele frequencies of the rs2736100 polymorphism between the patients with gastric cancer and healthy ***: The rs2736100 polymorphism of the h TERT gene is involved in the regulation of h TERT expression and telomere length,but not in the risk of gastric cancer.

关键词： Human telomerase reverse transcriptase Telomere Ga