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Comparative evaluations of visualization onboarding methods

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Visual Informatics 2022年第4期6卷 34-50页

作者： Christina Stoiber Conny Walchshofer Margit Pohl Benjamin Potzmann Florian Grassinger Holger Stitz Marc Streit wolfgang Aigner St.Poelten University of Applied Sciences St.PoeltenAustria Johannes Kepler University Linz LinzAustria TU Wien ViennaAustria datavisyn GmbH LinzAustria

Comprehending and exploring large and complex data is becoming increasingly important for a diverse population of users in a wide range of application *** has proven to be well-suited in supporting this endeavor by tapping into the power of human visual ***,non-experts in the field of visual data analysis often have problems with correctly reading and interpreting information from visualization idioms that are new to *** support novices in learning how to use new digital technologies,the concept of onboarding has been successfully applied in other fields and first approaches also exist in the visualization ***,empirical evidence on the effectiveness of such approaches is ***,we conducted three studies with Amazon Mechanical Turk(MTurk)workers and students investigating visualization onboarding at different levels:(1)Firstly,we explored the effect of visualization onboarding,using an interactive step-by-step guide,on user performance for four increasingly complex visualization techniques with time-oriented data:a bar chart,a horizon graph,a change matrix,and a parallel coordinates *** performed a between-subject experiment with 596 participants in *** results showed that there are no significant differences between the answer correctness of the questions with and without ***,participants commented that for highly familiar visualization types no onboarding is ***,for the most unfamiliar visualization type—the parallel coordinates plot—performance improvement can be observed with onboarding.(2)Thus,we performed a second study with MTurk workers and the parallel coordinates plot to assess if there is a difference in user performances on different visualization onboarding types:step-by-step,scrollytelling tutorial,and video *** study revealed that the video tutorial was ranked as the most positive on average,based on a sentiment analysis,followed by the scrollyt

关键词： Visualization literacy User onboarding Learning Visual analytic

Insights into Theranostic Properties of Titanium Dioxide for Nanomedicine

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Nano-Micro Letters 2020年第2期12卷 102-136页

作者： Morteza Hasanzadeh Kafshgari wolfgang HGoldmann Department of Engineering Physics Polytechnique MontreálMontrealQC H3C3A7Canada Department of Physics Biophysics GroupUniversity of Erlangen-Nuremberg91052 ErlangenGermany

Titanium dioxide(TiO2)nanostructures exhibit a broad range of theranostic properties that make them attractive for biomedical ***2 nanostructures promise to improve current theranostic strategies by leveraging the enhanced quantum confinement,thermal conversion,specific surface area,and surface *** review highlights certain important aspects of fabrication strategies,which are employed to generate multifunctional TiO2 nanostructures,while outlining post-fabrication techniques with an emphasis on their suitability for *** biodistribution,toxicity,biocompatibility,cellular adhesion,and endocytosis of these nanostructures,when exposed to biological microenvironments,are examined in regard to their geometry,size,and surface *** final section focuses on recent biomedical applications of TiO2 nanostructures,specifically evaluating therapeutic delivery,photodynamic and sonodynamic therapy,bioimaging,biosensing,tissue regeneration,as well as chronic wound healing.

关键词： TiO2 nanostructures Drug delivery systems Bioimaging Biosensing Tissue regeneration

Near vision examination in presbyopia patients: Do we need good homologated near vision charts?

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Eye and Vision 2016年第1期3卷 222-230页

作者： wolfgang Radner Austrian Academy of Ophthalmology Mollgasse 11A-1180 ViennaAustria

Presbyopia correction is mainly concerned with the goal of regaining an uncorrected reading *** historic reading charts do not provide a unique standard that is applicable for the analysis of clinical and scientific reading performance,new standardized reading charts have been developed,in order to provide reading performance analyses analogous to modern single-optotype distance acuity measurements:the Bailey-Lovie Word Reading Chart,the Colenbrander English Continuous Text Near Vision Cards,the MNREAD Charts,and the RADNER Reading *** last three are also meant to measure reading speed,thus allowing detailed analysis of the reading capabilities of the patient’s functional ***,these reading charts can be declared homologated,based on the standards that were published for reading charts by the Visual Function Committee of the International Council of Ophthalmology(ICO)in *** research studies have shown that by analyzing the reading performance with homologated reading charts,valuable insight into the reading performance of patients suffering from various diseases can be *** reading charts have also been successfully used in presbyopia *** therefore seems evident that homologated,standardized reading charts facilitate not only research concerning functional vision in many fields of ophthalmology but also international communication about near visual *** reading charts are available in almost all languages and have become a valuable tool in analyzing reading *** argue in this review that homologated reading charts are clearly a necessity for presbyopia research.

关键词： Reading charts Reading test Reading acuity Reading speed Reading performance Functional vision

Esophageal lichen planus:Current knowledge,challenges and future perspectives

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World Journal of Gastroenterology 2022年第41期28卷 5893-5909页

作者： Annegrit Decker Franziska Schauer Adhara Lazaro Carmen Monasterio Arthur Robert Schmidt Annette Schmitt-Graeff wolfgang Kreisel Department of Medicine II GastroenterologyHepatologyEndocrinology and Infectious DiseasesMedical Center-University of FreiburgFaculty of MedicineFreiburg 79106Germany Department of Dermatology Medical Center-University of FreiburgFaculty of MedicineFreiburg 79104Germany Department of Medicine Institute of Exercise and Occupational MedicineMedical Center–University of FreiburgFaculty of MedicineUniversity of FreiburgFreiburg 79106Germany Institute for Dermatohistology Pathologyand Molecular Pathology Prof.Dr.LaafFreiburgGermany and:University of FreiburgFreiburg 79106Germany

Lichen planus(LP)is a frequent,chronic inflammatory disease involving the skin,mucous membranes and/or skin *** involvement in lichen planus(ELP)is a clinically important albeit underdiagnosed inflammatory *** narrative review aims to give an overview of the current knowledge on ELP,its prevalence,pathogenesis,clinical manifestation,diagnostic criteria,and therapeutic options in order to provide support in clinical *** on ELP were collected using PubMed/*** clinical and therapeutical characteristics from published patient cohorts including our own cohort were extracted and *** mainly affects middle-aged *** principal symptom is ***,asymptomatic cases despite progressed macroscopic esophageal lesions may *** pathogenesis is unknown,however an immune-mediated mechanism is ***,ELP is characterized by mucosal denudation and tearing,trachealization,and *** esophageal stenosis may occur in chronic *** findings include mucosal detachment,T-lymphocytic infiltrations,epithelial apoptosis(Civatte bodies),dyskeratosis,and *** immuno-fluorescence shows fibrinogen deposits along the basement membrane *** date,there is no established ***,treatment with topical steroids induces symptomatic and histologic improvement in two thirds of ELP patients in *** severe cases may require therapy with *** symptomatic esophageal stenosis,endoscopic dilation may be *** may be regarded as a precancerous condition as transition to squamous cell carcinoma has been documented in *** is an underdiagnosed yet clinically important differential diagnosis for patients with unclear dysphagia or *** diagnosis and therapy might prevent potential sequelae such as esophageal stenosis or development of invasive squamous cell *** studies are needed to gain

关键词： Lichen planus Esophagitis T-lymphocytes Budesonide Dysphagia Precancerosis

THREE-DIMENSIONAL MATHEMATICAL MODEL AND ITS APPLICATION IN THE NEIGHBORHOOD OF THE THREE GORGES RESERVOIR DAM IN THE YANGTZE RIVER

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Acta Mechanica Sinica 2002年第3期18卷 235-243页

作者：方红卫 wolfgang Rodi Department of Hydraulic Engineering Tsinghua University Beijing China 100084 Institute for Hydromechanics University of Karlsruhe Karlsruhe 76128 Germany

The calculation of flow and sediment transport is one of the most important tasks in river engineering. The task is particularly difficult because a number of complex physical phenomena should be accounted for more realistically in a model with a predictive power. Three-dimensional calculations of river flow and suspended sediment transport are performed in this paper with application in the Three Gorges Reservoir in the Yangtze River. A period of 76 years after the dam is built is simulated and the results are compared with laboratory measurements obtained by Tsinghua University whereby the model is verified and calibrated. Generally speaking, the calculated results agree well with the experiments, demonstrating that the present model can be used for flow and sediment transport prediction in rivers.

关键词： three-dimensional mathematical model sediment transport Three Gorges Project (TGP)

COVID-19:Masks do not influence neurocognitive performance during a shift at the emergency department

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World Journal of Emergency Medicine 2023年第4期14卷 317-321页

作者： Jürgen Grafeneder Verena Fuhrmann Katharina Tscherny Maximilian Niederer wolfgang Schreiber Harald Herkner Dominik Roth Calvin Lukas Kienbacher Department of Emergency Medicine Medical University of ViennaWien 1090Austria Department of Anaesthesiology and Intensive Care Hospital ScheibbsScheibbs 3270Austria

The COVID-19 pandemic has led to the widespread mandatory use of personal protective equipment(PPE),including filtering face pieces(FFP).Emergency medical care providers now commonly use this equipment.

关键词： COV Mask protective

The Austrian node of the natural resources satellite remote sensing cloud service platform:examples of Sino-Austrian cooperation

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Geo-Spatial Information Science 2021年第1期24卷 145-151,I0015页

作者： wolfgang Kainz Xinming Tang Yucai Xue Department of Geography and Regional Research University of ViennaViennaAustria Land Satellite Remote Sensing Application Center Ministry of Natural Resources of the Peoples Republic of ChinaBeijingChina

The Austrian node of the Natural Resources Satellite Remote Sensing Cloud Service Platform was established in 2016 through a cooperation agreement between the Land Satellite Remote Sensing Application Center(LASAC),Ministry of Natural Resources of the Peoples Republic of China and the University of Vienna,*** this agreement panchromatic and multi-spectral data of the Chinese ZY-3 satellite are pushed to the server at the University of Vienna for use in education and *** far,nearly 500 GB of data have been uploaded to the *** technical note briefly introduces the ZY-3 system and illustrates the implementation of the agreement by the first China-Sat Workshop and several case *** of them are already completed,others are still *** include a geometric accuracy validation of ZY-3 data,an animated visualization of image quick views on a spherical display to demonstrate the time series of the image coverage for Austria and Laos,and the use of ZY-3 data to study the spread of bark beetle in the province of Lower *** accuracy study of DTMs from ZY-3 stereo data,as well as a land cover analysis and comparison of Austria with ZY-3 and other sensors are still ongoing.

关键词： Remote sensing geographic information systems ZY-3 satellite hyperglobe Land Satellite Remote Sensing Application Center(LASAC)

Implementing the GEOSS water strategy: from observations to decisions

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International Journal of Digital Earth 2023年第1期16卷 1439-1468页

作者： Richard Lawford Sushel Unninayar George J.Huffman wolfgang Grabs Angélica Gutiérrez Chu Ishida-Watanabe Toshio Koike Morgan State University BaltimoreUSA NASA Goddard Space Flight Center GreenbeltUSA International Water Affairs Federal Institute of HydrologyKoblenz National Oceanic and Atmospheric Administration Silver SpringUSA Japan Aerospace Exploration Agency Tsukuba International Centre for Water Hazard and Risk Management Tsukuba

In 2014,The GEOSS Water Strategy–From Observations to Decisions was published and steps were taken to implement the Strategy’s *** Strategy highlighted priority areas where the application of Earth observations to water research and water management decisions would have significant scientific and societal *** article reviews the implementation of the Strategy’s recommendations over the past eight *** a review of the Strategy’s assessment of the needs for water observations and their applications,it then reviews actions taken in response to the Strategy’s recommendations in its four major themes:improved data acquisition for Essential Water Variables,research and product development,interoperability,and capacity *** highlights significant achievements in the implementation of the Strategy including some motivated by factors beyond this Strategy,reviews actions taken by participating agencies and programs for each of the main themes and summarizes the remaining challenges in achieving the Strategy’s full *** article not only is an update for the Water Community regarding the GEOSS Water Strategy,but it is also an example of how other communities could develop and promulgate a set of strategic recommendations,monitor progress,and carry out assessments of their effectiveness.

关键词： Earth observations water essential water variables research interoperability capacity development

Wntl-regu｜ated genetic networks in midbrain dopaminergic neuron development

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Journal of Molecular Cell Biology 2014年第1期8卷 34-41页

作者： wolfgang Wurst Nilima Prakash Institute of Developmental Genetics Helmholtz Zentrum MCinchen German Research Center for Environmental Health and Technische Universit~it MCinchen-Weihenstephan Lehrstuhl for Entwicklungsgenetik Ingolst~idter Landstr. I 85764 Neuherberg Germany Deutsches Zentrum fiJr Neurodegenerative Erkrankungen (DZNE) Standort MiJnchen Schinerstr. 44 80336 MCinchen Germany Max Planck Institute of Psychiatry Kraepelinstrasse 2-10 80804 MiJnchen Germany

Neurons synthesizing the neurotransmitter dopamine exert crucial functions in the mammalian brain. The biggest and most important population of dopamine-synthesizing neurons is located in the mammalian ventral midbrain (VM), and controls and modulates the execution of motor, cognitive, affective, motivational, and rewarding behaviours. Degeneration of these neurons leads to motor deficits that are characteristic of Parkinson's disease, while their dysfunction is involved in the pathogenesis of psychiatric disorders including schizophrenia and addiction. Because the aetiology and therapeutic prospects for these diseases include neurodevelopmental aspects, substantial scientific interest has been focused on deciphering the mechanistic pathways that control the generation and survival of these neurons during embryonic development. Researches during the last decade revealed the pivotal role of the secreted Wnt1 ligand and its signalling cascade in the generation of the dopamine-synthesizing neurons in the mammalian VM. Here, we summarize the initial and more recent findings that have unravelled several Wnt1-controlled genetic networks required for the proliferation and commitment of VM progenitors to the dopaminergic cell fate during midgestational embryonic stages, and for the correct differentiation of these progenitors into postmitotic dopamine-synthesizing neurons at late midgestational embryonic and foetal stages.

关键词：多巴胺神经元神经元发育基因网络中脑胚胎发育过程哺乳动物运动障碍发病机制