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Chinese medicine practitioner turnover rate and the development of Chinese medicine in Hong Kong,China

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Journal of Traditional Chinese Medical Sciences 2021年第2期8卷 145-149页

作者： Ka-Kit Chua Vivien Lau wing-yan lee Chun-Pong Lam School of Chinese Medicine Hong Kong Baptist UniversityHong KongChina Sin-Hua Herbalist's&Herb Dealer's Promotion Society Limited Hong KongChina Alumni Association of Full-time Chinese Medicine Undergraduate Hong Kong Baptist UniversityHong KongChina

Objective:To establish that the Hong Kong Special Administrative Region(HKSAR)government is actively promoting Chinese medicine(CM)and to examine turnover rate of Chinese medicine practitioners(CMPs)in Hong Kong,China in light of this governmental ***:This study covered two major areas:reviewing CM development in Hong Kong,and assessing the turnover rate of CMPs in Hong *** first part of the paper is a historical *** investigation of turnover rate had two *** 1,quantitative method,involved online questionnaires;Section 2,qualitative method comprised interviews with CMPs from different types of CM clinics to ascertain the reasons for the turnover among ***:A total of 123 online questionnaires were received in Section 1(55 from male CMPs;66 from female CMPs;2 respondents were unwilling to disclose their sex).The proportion of CMPs who had resigned in 2018e19 was 22.8%(28),of whom 5.7%(7)had resigned twice in one *** rates of resignation in 3 years and 5 years were up to 40.7%(50)and 56.9%(70),*** CMPs were interviewed in Section *** CMPs were more likely to resign than *** large gap between actual salary and expectations appeared to be the main reason for the high rate of ***:HKSAR government keenly desires to promote CM in Hong Kong,however,high turnover rate of CMPs was detected even under this positive governmental *** is an urgent need to conduct a more representative study of the reasons for the inclination of CMPs in Hong *** study highlights an important issue in CM development,and these results should remind different stakeholders in the CM industry and the government that CMPs need better career prospects and support in various areas.

关键词： Chinese medicine development Chinese Medicine Turnover rate Hong Kong SAR Career prospect Salary

Heterogeneous Cu_(x)O Nano‑Skeletons from Waste Electronics for Enhanced Glucose Detection

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Nano-Micro Letters 2024年第11期16卷 554-568页

作者： Yexin Pan Ruohan Yu Yalong Jiang Haosong Zhong Qiaoyaxiao Yuan Connie Kong Wai lee Rongliang yang Siyu Chen Yi Chen wing yan Poon Mitch Guijun Li Center on Smart Manufacturing Division of Integrative Systems and DesignThe Hong Kong University of Science and TechnologyClear Water BayKowloonHong Kong SAR 999077People’s Republic of China The Sanya Science and Education Innovation Park of Wuhan University of Technology Sanya 572000People’s Republic of China State Key Laboratory of New Textile Materials and Advanced Processing Technologies Wuhan Textile UniversityWuhan 430200People’s Republic of China

Electronic waste(e-waste)and diabetes are global challenges to modern ***,solving these two challenges together has been challenging until ***,we propose a laser-induced transfer method to fabricate portable glucose sensors by recycling copper from *** bring up a laser-induced full-automatic fabrication method for synthesizing continuous heterogeneous Cu_(x)O(h-Cu_(x)O)nano-skeletons electrode for glucose sensing,offering rapid(<1 min),clean,air-compatible,and continuous fabrication,applicable to a wide range of Cu-containing *** this approach,h-Cu_(x)O nanoskeletons,with an inner core predominantly composed of Cu_(2)O with lower oxygen content,juxtaposed with an outer layer rich in amorphous Cu_(x)O(a-Cu_(x)O)with higher oxygen content,are derived from discarded printed circuit *** employed in glucose detection,the h-Cu_(x)O nano-skeletons undergo a structural evolution process,transitioning into rigid Cu_(2)O@CuO nano-skeletons prompted by electrochemical *** transformation yields exceptional glucose-sensing performance(sensitivity:9.893 mA mM^(-1) cm^(-2);detection limit:0.34μM),outperforming most previously reported glucose *** functional theory analysis elucidates that the heterogeneous structure facilitates gluconolactone *** glucose detection device has also been downsized to optimize its scalability and portability for convenient integration into people’s everyday lives.

关键词： Copper oxide Electron 3D tomography E-waste Glucose detection Electrochemical activation

Epitranscriptomic Regulation of NMDA Receptors Rears its Ugly Head in Chemotherapy-Induced Neuropathic Pain

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Neuroscience Bulletin 2024年第8期40卷 1209-1211页

作者： wing Lam Yu Gerald W.Zamponi Department of Clinical Neurosciences Hotchkiss Brain InstituteAlberta Children's Hospital Research InstituteUniversity of CalgaryCalgaryAB T2N 4N1Canada

A number of different cancer chemotherapy agents such as cisplatin,oxaliplatin,and paclitaxel can lead to nerve damage,thereby giving rise to neuropathic pain states that present with mechanical and cold allodynia[1].Although these pain conditions often resolve after completion of the chemotherapy,a significant portion of patients exhibit longlasting pain that can persist longer than 12 months with a negative impact on the quality of life of affected individuals[1].

关键词： chemotherapy pain damage

A study of the effect of local scour on the flow field near the spur dike

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Theoretical & Applied Mechanics Letters 2024年第2期14卷 98-105页

作者： Yu-Tian Li Jie-Min Zhan wing-Hong Onyx Wai Department of Industrial Design School of Industrial Design and Ceramic ArtFoshan UniversityFoshan 528000China Department of Applied Mechanics and Engineering Shenzhen Campus of Sun Yat-sen UniversityShenzhen 518107China Department of Civil and Environmental Engineering The Hong Kong Polytechnic UniversityHong Kong 999077China

The flow field near a spur dike such as down flow and horseshoe vortex system(HVS)are susceptible to the topographic changes in the local scouring process,resulting in variation of the sediment transport with *** this study,large eddy simulations with fixed-bed at different scouring stages were conducted to investigate the changes in flow *** results imply that the bed deformation leads to an increase in flow rate per unit area,which represent the capability of sediment transportation by water,in the scour ***,the intensity of turbulent kinetic energy and bimodal motion near the sand bed induced by the HVS were also ***,the peak moments between the two sediment transport mechanisms were ***,understanding the complex feedback mechanism between topography and flow field is essential for the local scour problem.

关键词： Spur dike Local scour Large eddy simulation Down flow Horseshoe vortex system

Optimal investment and consumption with forward preferences and uncertain parameters

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Probability, Uncertainty and Quantitative Risk 2024年第1期9卷 65-84页

作者： wing Fung Chong Gechun Liang Marwell Institute for Mathematical Sciences and Department of Actuarial Mathematics and Statistics Heriot-Watt UniversityEdinburgh EH144ASUK Department of Statistics The University of WarwickCoventry CV47ALUK

We introduce and analyze a class of forward performance criteria in incomplete markets in the presence of model *** stems from general investment constraints,while model uncertainty is represented by a convex and compact set of plausible model parameter *** the max-min criteria in traditional(backward)robust control,we formulate similar criteria for the robust forward performance processes and focus on the rich class of time-monotone *** provide a novel PDE characterization and a semi-explicit saddle-point construction of the robust forward performance criteria and their optimal ***,we present additional results within the class of homothetic constant relative risk aversion(CRRA)*** this class,we investigate the relationship between forward performance processes on wealth and those on consumption,establishing an interesting dominance through time.

关键词： Robust forward performance criteria Portfolio constraints Consumption Saddle points Constant relative risk aversion

Matrine-loaded self-adhesive swelling microneedle for inflammation regulation to improve eczema treatment

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Marine Life Science & Technology 2024年第3期6卷 535-546页

作者： Jiale Shen Jiarui Wang Meng Wu yan Shi Minhyeock lee Zhiguo Wang Ming Kong College of Marine Life Sciences Ocean University of ChinaQingdao 266003China Department of Burn and Plastic Surgery the Affiliated Hospital of Qingdao UniversityQingdao UniversityQingdao 266021China Department of Biotechnology College of Life Sciences and BiotechnologyKorea UniversitySeoul 02841Republic of Korea

Eczema is a common chronic dermatological *** treatments exhibit limited efficacy due to fast drug release resulting in short-term *** of a new treatment strategy that enables sustained drug release and longterm maintenance on the skin surface is necessary.A self-adhesive swelling microneedle patch(SDSMNs)was designed and constructed using a two-step casting *** adhesive substrate was prepared by blending gelatin and dopamine via oxidation of NaIO4,so it could adhere onto the skin surface as well as withstand repeated bending movement without *** swelling needles were fabricated using polyvinyl alcohol(PVA)and polyvinylpyrrolidone(PVP),which could swell by absorbing interstitial fluid and release the drug in a controlled *** also showed desirable antibacterial activities toward *** and *** adhesive microneedles loaded with matrine(MAT-SDSMNs),an antiinflammatory Chinese medicine,dramatically relieved eczema symptoms through IL-17 mediated inflammation *** use of MAT-SDSMNs significantly decreased the infiltration of inflammation cells and level of inflammatory cytokines,reduced the skin thickness,and increased collagen deposition fraction compared with conventional ointment or subcutaneous *** results suggested that MAT-SDSMNs can improve eczema treatment by regulating the local inflammatory microenvironment,providing a simple,self-administered sustainable strategy for eczema treatment.

关键词： Self-adhesive swelling microneedle Eczema Matrine Inflammation regulation

Association of accelerometer-measured sleep duration and different intensities of physical activity with incident type 2 diabetes in a population-based cohort study

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Journal of Sport and Health Science 2024年第2期13卷 222-232页

作者： Xinyi Jin Yilin Chen Hongliang Feng Mingqing Zhou Joey W.Y.Chang Yaping Liu Alice Pik Shan Kong Xiao Tan Yun-Kwok wing yannis yan Liang Jihui Zhang Guangdong Cardiovascular Institute Guangdong Provincial People’s HospitalGuangdong Academy of Medical SciencesGuangzhou 510080China Guangdong Provincial Key Laboratory of Coronary Heart Disease Prevention Guangdong Cardiovascular InstituteGuangdong Provincial People’s Hospital(Guangdong Academy of Medical Sciences)Southern Medical UniversityGuangzhou 510080China School of Medicine South China University of TechnologyGuangzhou 510641China Center for Sleep and Circadian Medicine The Affiliated Brain Hospital of Guangzhou Medical UniversityGuangzhou 510180China The Second School of Clinical Medicine Southern Medical UniversityGuangzhou 510282China Guangdong Mental Health Center Guangdong Provincial People’s Hospital(Guangdong Academy of Medical Sciences)Southern Medical UniversityGuangzhou 510120China Li Chiu Kong Family Sleep Assessment Unit Department of PsychiatryFaculty of MedicineThe Chinese University of Hong KongHong Kong 999077China Department of Psychiatry Faculty of MedicineThe Chinese University of Hong KongHong Kong 999077China Department of Medicine and Therapeutics Faculty of MedicineThe Chinese University of Hong KongHong Kong 999077China Department of Medical Sciences Uppsala UniversityUppsala 75185Sweden Department of Big Data in Health Science Zhejiang University School of Public HealthHangzhou 310058China Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China Guangzhou 510260China

Purpose:The aim of the current study was to investigate the association of accelerometer-measured sleep duration and different intensities of physical activity(PA)with the risk of incident type 2 diabetes in a population-based prospective cohort ***:Altogether,88,000 participants(mean age=62.2±7.9 years,mean±SD)were included from the UK *** duration(short:8 h/day)and PA of different intensities were measured using a wrist-won accelerometer over a 7-day period between 2013 and *** was classified according to the median or World Health Organization-recommendation:total volume of PA(high,low),moderate-to-vigorous PA(MVPA)(recommended,not recommended),and light-intensity PA(high,low).Incidence of type 2diabetes was ascertained using hospital records or death ***:During a median follow-up of 7.0 years,1615 incident type 2 diabetes cases were *** with normal sleep duration,short(hazard ratio(HR)=1.21,95%confidence interval(95%CI):1.03-1.41)but not long sleep duration(HR=1.01,95%CI:0.89-1.15)was associated with excessive type 2 diabetes *** increased risk among short sleepers seems to be protected against by *** with normal sleepers with high or recommended PA,short sleepers with low volume of PA(HR=1.81,95%CI:1.46-2.25),not recommended(below the World Health Organization-recommended level of)MVPA(HR=1.92,95%CI:1.55-2.36),or low light-intensity PA(HR=1.49,95%CI:1.13-1.90)had a higher risk of type 2 diabetes,while short sleepers with a high volume of PA(HR=1.14,95%CI:0.88-1.49),recommended MVPA(HR=1.02,95%CI:0.71-1.48),or high light-intensity PA(HR=1.14,95%CI:0.92-1.41)did ***:Accelerometer-measured short but not long sleep duration was associated with a higher risk of incident type 2 diabetes.A higher level of PA,regardless of intensity,potentially ameliorates this excessive risk.

关键词： Light physical activity Sleep duration Triaxial accelerometer Type 2 diabetes UK Biobank

Mathematical Modeling of Cell Polarity Establishment of Budding Yeast

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Communications on Applied Mathematics and Computation 2024年第1期6卷 218-235页

作者： Yue Liu Jun Xie Hay-Oak Park wing-Cheong Lo Department of Mathematics City University of Hong KongTat Chee AvenueKowloonHong KongChina Department of Molecular Genetics The Ohio State UniversityColumbusOHUSA

The budding yeast Saccharomyces cerevisiae is a powerful model system for studying the cell polarity *** cell polarization process is regulated by signaling molecules,which are initially distributed in the cytoplasm and then recruited to a proper location on the cell membrane in response to spatial cues or *** of these signaling molecules involves complex regulation,so the mathematical models become a useful tool to investigate the mechanism behind the *** this review,we discuss how mathematical modeling has shed light on different regulations in the cell *** also propose future applications for the mathematical modeling of cell polarization and morphogenesis.

关键词： Budding yeast Cdc42 Morphogenesis Septin Mathematical models

Towards Data-Driving Multi-View Evaluation Framework for Scratch

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Tsinghua Science and Technology 2024年第2期29卷 517-528页

作者： Xiaolin Chai yan Sun yan Gao Department of Computer Science Beijing University of Posts and TelecommunicationBeijing 100876China Intellectual Property Institute Shandong Polytechnic CollegeJining 272067China

As one of the most popular visual programming languages,Scratch has a lot of evaluation around *** evaluation can help programmers understand their projects *** the same time,it can also provide a reference for them to browse other projects in the online *** of the existing evaluations on Scratch are carried from three perspectives:Computational Thinking(CT)ability,visual presentation aesthetics,and code *** them,the assessment of CT and code quality is mainly carried out from the program script,while the evaluation of visual aesthetics is analyzed from the perspective of image sequences generated by project *** single-view evaluation focuses on the performance of a program in a certain aspect and is *** this paper,we propose a multi-view evaluation framework to integrate various evaluations using different *** quantitatively analyze the assessment of different views driven by *** with overall evaluations that represent human opinions,we analyze their differences and *** experiments,we determine the weights of different integration policies,the proposed multi-view evaluation method can generate evaluation results similar to human opinions.

关键词： Scratch Computational Thinking(CT) visual aesthetic static analysis integration policy machine learning